KEGG   ENZYME: 4.2.1.146Help
Entry
EC 4.2.1.146                Enzyme                                 

Name
L-galactonate dehydratase;
LGD1
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
L-galactonate hydro-lyase (2-dehydro-3-deoxy-L-galactonate-forming)
Reaction(IUBMB)
L-galactonate = 2-dehydro-3-deoxy-L-galactonate + H2O [RN:R10532]
Reaction(KEGG)
Substrate
L-galactonate [CPD:C15930]
Product
2-dehydro-3-deoxy-L-galactonate [CPD:C20680];
H2O [CPD:C00001]
Comment
The enzyme takes part in a D-galacturonate degradation pathway in the fungi Trichoderma reesei (Hypocrea jecorina) and Aspergillus niger.
History
EC 4.2.1.146 created 2013
Pathway
ec00040  Pentose and glucuronate interconversions
ec01100  Metabolic pathways
Orthology
K18102  L-galactonate dehydratase
Genes
QSU: 111983292 111987843
PPA: PAS_chr4_0572
PGU: PGUG_05189
CTEN: CANTEDRAFT_135663
SLB: AWJ20_3253 AWJ20_3295
NCR: NCU07064
NTE: NEUTE1DRAFT131658(NEUTE1DRAFT_131658)
SMP: SMAC_03881
PAN: PODANSg3017
TTT: THITE_2153466
MGR: MGG_01300
MAW: MAC_03404
MAJ: MAA_02004
CMT: CCM_00320
BFU: BCIN_01g09450(Bclgd1)
MBE: MBM_09691
ANI: AN6035.2
ANG: ANI_1_1784144(An16g05390)
ABE: ARB_05174
TVE: TRV_03587
PTE: PTT_15544
 » show all
Taxonomy
Reference
1  [PMID:16879654]
  Authors
Kuorelahti S, Jouhten P, Maaheimo H, Penttila M, Richard P
  Title
L-galactonate dehydratase is part of the fungal path for D-galacturonic acid catabolism.
  Journal
Mol Microbiol 61:1060-8 (2006)
DOI:10.1111/j.1365-2958.2006.05294.x
  Sequence
Reference
2  [PMID:18768163]
  Authors
Martens-Uzunova ES, Schaap PJ
  Title
An evolutionary conserved d-galacturonic acid metabolic pathway operates across filamentous fungi capable of pectin degradation.
  Journal
Fungal Genet Biol 45:1449-57 (2008)
DOI:10.1016/j.fgb.2008.08.002
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.146
IUBMB Enzyme Nomenclature: 4.2.1.146
ExPASy - ENZYME nomenclature database: 4.2.1.146
BRENDA, the Enzyme Database: 4.2.1.146
LinkDB All DBs

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