Entry |
|
Name |
L-3-cyanoalanine synthase;
beta-cyanoalanine synthase;
beta-cyanoalanine synthetase;
beta-cyano-L-alanine synthase;
L-cysteine hydrogen-sulfide-lyase (adding HCN)
|
Class |
Lyases;
Carbon-sulfur lyases;
Carbon-sulfur lyases (only sub-subclass identified to date)
|
Sysname |
L-cysteine hydrogen-sulfide-lyase (adding hydrogen cyanide; L-3-cyanoalanine-forming)
|
Reaction(IUBMB) |
L-cysteine + hydrogen cyanide = L-3-cyanoalanine + hydrogen sulfide [RN: R03524]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
L-3-cyanoalanine [CPD: C02512];
hydrogen sulfide [CPD: C00283]
|
Comment |
Contains pyridoxal phospate.
|
History |
EC 4.4.1.9 created 1972, deleted 1976, reinstated 1978
|
Pathway |
ec01110 | Biosynthesis of secondary metabolites |
|
Orthology |
K13034 | L-3-cyanoalanine synthase/ cysteine synthase |
|
Genes |
» show all
|
Reference |
|
Authors |
Akopyan TN, Braunstein AE, Goryachenkova EV. |
Title |
Beta-cyanoalanine synthase: purification and characterization. |
Journal |
|
Reference |
|
Authors |
Castric PA, Conn EE. |
Title |
Formation of -cyanoalanine by O-acetylserine sulfhydrylase. |
Journal |
|
Reference |
3 |
Authors |
Hendrickson, H.R. |
Title |
The beta-cyanoalanine synthase of blue lupine. |
Journal |
Fed Proc 27:593 (1968) |
Reference |
|
Authors |
Hendrickson HR, Conn EE. |
Title |
Cyanide metabolism in higher plants. IV. Purification and properties of the beta-cyanolanine synthase of blue lupine. |
Journal |
J Biol Chem 244:2632-40 (1969) |
Other DBs |
ExplorEnz - The Enzyme Database: | 4.4.1.9 |
ExPASy - ENZYME nomenclature database: | 4.4.1.9 |
BRENDA, the Enzyme Database: | 4.4.1.9 |
|
LinkDB |
|