Entry |
|
Name |
maleylacetoacetate isomerase;
maleylacetoacetic isomerase;
maleylacetone isomerase;
maleylacetone cis-trans-isomerase
|
Class |
Isomerases;
cis-trans-Isomerases;
cis-trans Isomerases (only sub-subclass identified to date)
|
Sysname |
4-maleylacetoacetate cis-trans-isomerase
|
Reaction(IUBMB) |
4-maleylacetoacetate = 4-fumarylacetoacetate [RN: R03181]
|
Reaction(KEGG) |
|
Substrate |
4-maleylacetoacetate [CPD: C01036]
|
Product |
4-fumarylacetoacetate [CPD: C01061]
|
Comment |
Also acts on maleylpyruvate.
|
History |
EC 5.2.1.2 created 1961
|
Pathway |
ec01120 | Microbial metabolism in diverse environments |
|
Orthology |
K01800 | maleylacetoacetate isomerase |
|
Genes |
» show all
|
Reference |
|
Authors |
EDWARDS SW, KNOX WE. |
Title |
Homogentisate metabolism: the isomerization of maleylacetoacetate by an enzyme which requires glutathione. |
Journal |
J Biol Chem 220:79-91 (1956) |
Reference |
|
Authors |
LACK L. |
Title |
Enzymic cis-trans isomerization of maleylpyruvic acid. |
Journal |
J Biol Chem 236:2835-40 (1961) |
Reference |
|
Authors |
Seltzer S. |
Title |
Purification and properties of maleylacetone cis-trans isomerase from vibrio 01. |
Journal |
J Biol Chem 248:215-22 (1973) |
Other DBs |
ExplorEnz - The Enzyme Database: | 5.2.1.2 |
ExPASy - ENZYME nomenclature database: | 5.2.1.2 |
UM-BBD (Biocatalysis/Biodegradation Database): | 5.2.1.2 |
BRENDA, the Enzyme Database: | 5.2.1.2 |
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LinkDB |
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