Equus caballus (horse): 100033860
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Entry
100033860 CDS
T01058
Gene name
TGFBR2
Definition
(RefSeq) TGF-beta receptor type-2
KO
K04388
TGF-beta receptor type-2 [EC:
2.7.11.30
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb04010
MAPK signaling pathway
ecb04060
Cytokine-cytokine receptor interaction
ecb04068
FoxO signaling pathway
ecb04144
Endocytosis
ecb04218
Cellular senescence
ecb04350
TGF-beta signaling pathway
ecb04380
Osteoclast differentiation
ecb04390
Hippo signaling pathway
ecb04520
Adherens junction
ecb04659
Th17 cell differentiation
ecb04926
Relaxin signaling pathway
ecb04933
AGE-RAGE signaling pathway in diabetic complications
ecb05142
Chagas disease
ecb05161
Hepatitis B
ecb05166
Human T-cell leukemia virus 1 infection
ecb05200
Pathways in cancer
ecb05202
Transcriptional misregulation in cancer
ecb05210
Colorectal cancer
ecb05212
Pancreatic cancer
ecb05220
Chronic myeloid leukemia
ecb05225
Hepatocellular carcinoma
ecb05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100033860 (TGFBR2)
04350 TGF-beta signaling pathway
100033860 (TGFBR2)
04390 Hippo signaling pathway
100033860 (TGFBR2)
04068 FoxO signaling pathway
100033860 (TGFBR2)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
100033860 (TGFBR2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100033860 (TGFBR2)
09143 Cell growth and death
04218 Cellular senescence
100033860 (TGFBR2)
09144 Cellular community - eukaryotes
04520 Adherens junction
100033860 (TGFBR2)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
100033860 (TGFBR2)
09152 Endocrine system
04926 Relaxin signaling pathway
100033860 (TGFBR2)
09158 Development and regeneration
04380 Osteoclast differentiation
100033860 (TGFBR2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100033860 (TGFBR2)
05202 Transcriptional misregulation in cancer
100033860 (TGFBR2)
09162 Cancer: specific types
05210 Colorectal cancer
100033860 (TGFBR2)
05212 Pancreatic cancer
100033860 (TGFBR2)
05225 Hepatocellular carcinoma
100033860 (TGFBR2)
05226 Gastric cancer
100033860 (TGFBR2)
05220 Chronic myeloid leukemia
100033860 (TGFBR2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100033860 (TGFBR2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100033860 (TGFBR2)
05161 Hepatitis B
100033860 (TGFBR2)
09174 Infectious disease: parasitic
05142 Chagas disease
100033860 (TGFBR2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100033860 (TGFBR2)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
100033860 (TGFBR2)
Protein kinases [BR:
ecb01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
100033860 (TGFBR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ecTbetaR2
PK_Tyr_Ser-Thr
Pkinase
Pkinase_fungal
APH
Motif
Other DBs
NCBI-GeneID:
100033860
NCBI-ProteinID:
NP_001288076
Ensembl:
ENSECAG00000015269
VGNC:
24056
LinkDB
All DBs
Position
16
AA seq
531 aa
AA seq
DB search
MVTDNDGAVKFPQFCKFCNVSSSICDNQKSCMSNCSITSRCEKPREVCVAVWRKNDKNIT
LETVCHDPKLTYHGFVLEDAASPKCIMKEKKVSGETFFMCSCSSDECNDHIIFSEEYATN
NPDLLLVIFQVTGVSLLPPLGIAIAVIITFYCYRVHRQQKLSPSWETSKPRKLMEFSEHL
AIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAV
KIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEY
LTRHVISWEDLRKLGSSLARGIAHLHSDHTLCGRPKMPIVHRDLKSSNILVKNDLTCCLC
DFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWE
MTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSSWLNHQGIQMVCET
LTECWDHDPEARLTAQCVAERFSELEHMDRLSGRSCSEEKIPEDGSLNTTK
NT seq
1596 nt
NT seq
+upstream
nt +downstream
nt
atggtcactgacaacgacggtgcagtcaagtttccacaattttgtaaattttgcaacgtg
agctcttccatctgtgacaaccagaaatcctgcatgagcaactgcagcatcacgtccaga
tgtgagaagccacgcgaagtctgtgtggctgtctggagaaagaatgataagaacataaca
ctagagacggtttgccatgaccccaagctcacctaccatggatttgttcttgaagatgct
gcttctccaaagtgtattatgaaggaaaaaaaagtgtctggcgagactttctttatgtgt
tcctgtagctctgatgagtgcaacgaccacatcatcttctcagaagaatatgccaccaac
aaccctgacttgttgttagtcatattccaagtgacaggcgtcagcctcctgccaccgctg
ggaattgccattgcggtcatcatcaccttctactgctaccgcgttcaccggcagcagaag
ctgagcccgtcctgggagaccagcaagccacggaagctcatggagttcagcgagcacctt
gccatcattctggaagacgaccgctccgacatcagctctacgtgtgccaacaatatcaac
cacaacacagagctgctgcccattgagctggacaccctggtggggaaaggtcgctttgct
gaggtctacaaggccaagctgaagcagaacacttcagagcagtttgagaccgtggcagtc
aagatctttccttatgaggagtacgcctcctggaagacagagaaggacattttttcagac
atcaacctgaagcatgagaacatactccagttcctgacagctgaggagcgaaagacagaa
ctgggaaagcaatattggctgatcaccgctttccatgccaagggcaacctacaggaatac
cttacacggcatgtcatcagctgggaggacctgcgcaagctaggcagctccctagcccgg
ggcattgctcacctgcacagtgaccacaccctgtgcgggaggcccaagatgcccattgtg
cacagggacctcaagagctccaacatcctcgtgaagaatgacctgacctgctgcctgtgt
gactttgggctttccctgcgtttggacccgaccctgtctgtggatgacctggccaacagt
gggcaggtgggaactgcaagatacatggccccagaagtcctggagtccaggatgaatttg
gagaatgttgagtccttcaagcagacagatgtctactccatggctctggtgctctgggaa
atgacatctcgctgtaacgcagtgggagaagtgaaagattatgagcctccatttggttcc
aaggtgcgggagcatccctgtgtcgaaagcatgaaggacaatgtcttgagagatcgagga
cgaccagaaattcccagctcctggctcaaccaccagggcatccagatggtgtgtgagact
ctgaccgagtgctgggaccacgacccggaggcccgtctcacggcccagtgcgtggcggaa
cgcttcagcgagctggagcacatggacagactctcggggaggagctgctccgaggagaag
attcccgaagacggctcgctgaacactaccaaatag
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