KEGG   Equus caballus (horse): 100034011
Entry
100034011         CDS       T01058                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3
  KO
K04692  signal transducer and activator of transcription 3
Organism
ecb  Equus caballus (horse)
Pathway
ecb01521  EGFR tyrosine kinase inhibitor resistance
ecb04062  Chemokine signaling pathway
ecb04066  HIF-1 signaling pathway
ecb04068  FoxO signaling pathway
ecb04217  Necroptosis
ecb04550  Signaling pathways regulating pluripotency of stem cells
ecb04630  JAK-STAT signaling pathway
ecb04659  Th17 cell differentiation
ecb04917  Prolactin signaling pathway
ecb04920  Adipocytokine signaling pathway
ecb04931  Insulin resistance
ecb04933  AGE-RAGE signaling pathway in diabetic complications
ecb04935  Growth hormone synthesis, secretion and action
ecb05145  Toxoplasmosis
ecb05160  Hepatitis C
ecb05161  Hepatitis B
ecb05162  Measles
ecb05163  Human cytomegalovirus infection
ecb05167  Kaposi sarcoma-associated herpesvirus infection
ecb05169  Epstein-Barr virus infection
ecb05200  Pathways in cancer
ecb05203  Viral carcinogenesis
ecb05205  Proteoglycans in cancer
ecb05206  MicroRNAs in cancer
ecb05212  Pancreatic cancer
ecb05221  Acute myeloid leukemia
ecb05223  Non-small cell lung cancer
ecb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ecb05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100034011 (STAT3)
   04066 HIF-1 signaling pathway
    100034011 (STAT3)
   04068 FoxO signaling pathway
    100034011 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100034011 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100034011 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100034011 (STAT3)
   04062 Chemokine signaling pathway
    100034011 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    100034011 (STAT3)
   04917 Prolactin signaling pathway
    100034011 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    100034011 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100034011 (STAT3)
   05206 MicroRNAs in cancer
    100034011 (STAT3)
   05205 Proteoglycans in cancer
    100034011 (STAT3)
   05203 Viral carcinogenesis
    100034011 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100034011 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100034011 (STAT3)
   05221 Acute myeloid leukemia
    100034011 (STAT3)
   05223 Non-small cell lung cancer
    100034011 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100034011 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100034011 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100034011 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    100034011 (STAT3)
   05161 Hepatitis B
    100034011 (STAT3)
   05160 Hepatitis C
    100034011 (STAT3)
   05163 Human cytomegalovirus infection
    100034011 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100034011 (STAT3)
   05169 Epstein-Barr virus infection
    100034011 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100034011 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100034011 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ecb03000]
    100034011 (STAT3)
Transcription factors [BR:ecb03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    100034011 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 DUF4795 Syntaxin-6_N AP1AR Fib_alpha
Other DBs
NCBI-GeneID: 100034011
NCBI-ProteinID: NP_001296441
Ensembl: ENSECAG00000016439
VGNC: 23665
UniProt: A0A3Q2L9H8
LinkDB
Position
11
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctgcagcagctcgacacccggtacctggagcagctccatcag
ctgtacagtgacagcttcccgatggagctgcggcaatttctggccccttggattgagagt
caagattgggcgtatgcggccagcaaagaatcacatgccactttggtgtttcataatctc
ttgggtgagattgaccagcagtacagccgcttcctccaagagtcaaacgtcctctatcag
cacaatctgcgaagaatcaagcagttccttcagagcaggtatctcgagaagccaatggag
attgcccgaattgtggcccgatgcctgtgggaagagtcccgcctcctccagactgcagcc
actgcagcccagcaagggggccaggccaatcaccccaccgcggccgtggtgacggagaag
cagcagatgctggagcagcacctgcaggatgttcggaagcgagtacaggatctagaacag
aaaatgaaagtggtagagaatctccaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaggatctgaatggaaacaaccagtcagtgaccaggcagaagatg
cagcagctggaacagatgcttactgcgctggaccagatgcggcgaagcatcgtgagtgag
ttggcggggcttctgtcagctatggagtatgtgcagaagactctcacggatgaagagctg
gctgactggaagaggcgacaacagattgcttgcatcggaggccctcccaacatctgccta
gatcgtctagaaaactggataacctcattagcagaatctcaacttcagacccgccaacaa
attaagaaactggaggagttgcagcagaaagtttcctataaaggagaccccatcgtacag
caccggcccatgctcgaggagagaattgtggagctgtttagaaacttaatgaaaagtgcc
tttgtggttgagcggcagccctgcatgcccatgcatcccgaccggcccttagtcatcaag
accggtgtccagtttactactaaagtcagattgctggtcaaatttccggaattaaattat
cagcttaaaattaaagtgtgcattgacaaagactccggggacgttgcagctctcagagga
tcccggaaatttaacattctgggcacaaacacaaaagtgatgaacatggaagagtccaac
aacggcagcctctctgcagagttcaaacacttgaccctgagagagcaaagatgtggtaac
gggggccgagccaattgtgacgcctccctgattgtgaccgaggagctgcacctgatcacc
tttgagactgaagtgtatcaccaaggcctcaagattgaccttgagacccactccctgcca
gttgtggtgatctccaacatctgtcagatgccaaatgcctgggcctcaatcttgtggtat
aacatgctgaccaacaaccccaagaacgtgaactttttcaccaagcccccaattggaacc
tgggatcaagtggccgaggtgctgagctggcagttctcctccaccaccaagcggggactg
agcatcgagcagttgaccacgctggcagagaaactcttagggccgggtgtgaactattca
gggtgtcagatcacgtgggctaaattttgcaaagaaaacatggctggcaagggcttctcc
ttctgggtctggctggacaatatcattgatcttgtgaaaaagtacatcctggccctctgg
aatgaagggtacataatgggctttatcagtaaggagcgggagcgggccatcttgagcacc
aagcccccaggcaccttcctgctgagattcagtgaaagcagcaaagaaggaggcgtcacc
ttcacttgggtggagaaggacatcagcggtaagactcagatccagtcagtagaaccatat
accaagcagcagctgaacaacatgtcgtttgctgagatcatcatgggctacaagatcatg
gatgccaccaatatcctggtgtctccgctggtctatctctaccccgacattccaaaggag
gaggccttcggaaagtactgtcggccagagagccaggagcatcctgaagccgacccaggt
agtgctgccccatacctgaagaccaagtttatctgtgtgacaccaacgacctgcagtaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgagccctcagcaggagggcagtttgagtccctcacattcgacatggag
ttgacctcggagtgcgctacctcccccatgtga

DBGET integrated database retrieval system