Equus caballus (horse): 100051295 Help Entry 100051295         CDS       T01058                                  Gene name ADCY6 Definition (RefSeq) adenylate cyclase type 6 isoform X2   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism ecb  Equus caballus (horse) Pathway ecb00230   Purine metabolism ecb01100   Metabolic pathways ecb01522   Endocrine resistance ecb04015   Rap1 signaling pathway ecb04022   cGMP-PKG signaling pathway ecb04024   cAMP signaling pathway ecb04062   Chemokine signaling pathway ecb04072   Phospholipase D signaling pathway ecb04114   Oocyte meiosis ecb04211   Longevity regulating pathway ecb04213   Longevity regulating pathway - multiple species ecb04261   Adrenergic signaling in cardiomyocytes ecb04270   Vascular smooth muscle contraction ecb04371   Apelin signaling pathway ecb04540   Gap junction ecb04611   Platelet activation ecb04713   Circadian entrainment ecb04714   Thermogenesis ecb04723   Retrograde endocannabinoid signaling ecb04724   Glutamatergic synapse ecb04725   Cholinergic synapse ecb04727   GABAergic synapse ecb04742   Taste transduction ecb04750   Inflammatory mediator regulation of TRP channels ecb04911   Insulin secretion ecb04912   GnRH signaling pathway ecb04913   Ovarian steroidogenesis ecb04914   Progesterone-mediated oocyte maturation ecb04915   Estrogen signaling pathway ecb04916   Melanogenesis ecb04918   Thyroid hormone synthesis ecb04921   Oxytocin signaling pathway ecb04923   Regulation of lipolysis in adipocytes ecb04924   Renin secretion ecb04925   Aldosterone synthesis and secretion ecb04926   Relaxin signaling pathway ecb04927   Cortisol synthesis and secretion ecb04928   Parathyroid hormone synthesis, secretion and action ecb04934   Cushing syndrome ecb04935   Growth hormone synthesis, secretion and action ecb04961   Endocrine and other factor-regulated calcium reabsorption ecb04962   Vasopressin-regulated water reabsorption ecb04970   Salivary secretion ecb04971   Gastric acid secretion ecb04972   Pancreatic secretion ecb04976   Bile secretion ecb05032   Morphine addiction ecb05163   Human cytomegalovirus infection ecb05166   Human T-cell leukemia virus 1 infection ecb05200   Pathways in cancer ecb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ecb00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100051295 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100051295 (ADCY6)    04371 Apelin signaling pathway     100051295 (ADCY6)    04072 Phospholipase D signaling pathway     100051295 (ADCY6)    04024 cAMP signaling pathway     100051295 (ADCY6)    04022 cGMP-PKG signaling pathway     100051295 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100051295 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     100051295 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100051295 (ADCY6)    04062 Chemokine signaling pathway     100051295 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     100051295 (ADCY6)    04923 Regulation of lipolysis in adipocytes     100051295 (ADCY6)    04912 GnRH signaling pathway     100051295 (ADCY6)    04913 Ovarian steroidogenesis     100051295 (ADCY6)    04915 Estrogen signaling pathway     100051295 (ADCY6)    04914 Progesterone-mediated oocyte maturation     100051295 (ADCY6)    04921 Oxytocin signaling pathway     100051295 (ADCY6)    04926 Relaxin signaling pathway     100051295 (ADCY6)    04935 Growth hormone synthesis, secretion and action     100051295 (ADCY6)    04918 Thyroid hormone synthesis     100051295 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     100051295 (ADCY6)    04916 Melanogenesis     100051295 (ADCY6)    04924 Renin secretion     100051295 (ADCY6)    04925 Aldosterone synthesis and secretion     100051295 (ADCY6)    04927 Cortisol synthesis and secretion     100051295 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100051295 (ADCY6)    04270 Vascular smooth muscle contraction     100051295 (ADCY6)   09154 Digestive system    04970 Salivary secretion     100051295 (ADCY6)    04971 Gastric acid secretion     100051295 (ADCY6)    04972 Pancreatic secretion     100051295 (ADCY6)    04976 Bile secretion     100051295 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     100051295 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     100051295 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     100051295 (ADCY6)    04727 GABAergic synapse     100051295 (ADCY6)    04725 Cholinergic synapse     100051295 (ADCY6)    04723 Retrograde endocannabinoid signaling     100051295 (ADCY6)   09157 Sensory system    04742 Taste transduction     100051295 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     100051295 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     100051295 (ADCY6)    04213 Longevity regulating pathway - multiple species     100051295 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     100051295 (ADCY6)    04714 Thermogenesis     100051295 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100051295 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     100051295 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100051295 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100051295 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100051295 (ADCY6)    05163 Human cytomegalovirus infection     100051295 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100051295 (ADCY6) Enzymes [BR:ecb01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100051295 (ADCY6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD Shisa Motif Other DBs NCBI-GeneID:  100051295 NCBI-ProteinID:  XP_001504149 Ensembl:  ENSECAG00000022288 VGNC:  15091 LinkDB All DBs Position 6 AA seq 1166 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRQRRGTRTSGFCAPRYISCLQDAQPPSPTPAAPA QCRWQDEAFIRRGGPGKGKELGLRAVALAFEDTEAAAVARAAEVAPDVAPRSRRSCWRRL VQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPAPPQPAYVA LLACAAALFVALMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPHSPSVGLWCP VFFVYITYTLLPIRMRAAVFSGLGLSTLHLILAWQLNRGDAFLWKQLGANMMLFLCTNVI GICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKK EDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLR IKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHC GVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYL KEQHIETFLILGASQKRKEEKAMLAKLQRTRANSVEGLMPRWVPDRAFSRAKDSKAFRQM GIDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYS RKVDPRFGAYVACALLVFCFICFIQLLIFPHSTLMLGIYASIFLLLLITVLTCAVYSCGS LFPKALQRLSRSIVRSRAHSTVVGIFSVLLVFTSAIANMFTCNHTPIRTCAARMLNLTPA DITACHLQQLNYSLGLDAPLCEDTAPTCSFPEYLVGNMLLSLLASSVFLHISSIGKLAMI FVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTPVIL LVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLA RERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEE RFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQ MKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQ LECRGVVKVKGKGEMTTYFLNGGPSS NT seq 3501 nt NT seq  +upstreamnt  +downstreamnt atgtcgtggtttagtggcctcctggtccccaaagtggatgaacggaaaacagcctggggt gaacgcaatgggcagaagcgacaacgccgcggcacacggaccagtggtttctgtgcaccc cgctacataagctgcctccaggatgcacagccacccagccccacccctgcagctcccgct cagtgccgctggcaggatgaggccttcatccggaggggtggcccaggcaagggcaaggag ctggggctgcgggccgtggccctggcctttgaggacactgaggcagcagcagtggccagg gcggctgaggtggcgcctgatgtggcccccaggagcagacgatcctgctggcgccgtctg gtgcaggtgttccagtcgaagcagttccgctcagccaagctggagcgcctgtaccagcgg tacttctttcagatgaaccagagcagcctgacgctgctgatggcggtgctcgtgctgctc acagctgtgctgctggccttccatgctgcgcctgcccctcctcagcctgcctacgtggcc ctgctggcctgtgccgctgccctctttgtggcacttatggtggtgtgtaaccgacacagc ttccgccaggactccatgtgggtggtaagctacgtggtgctaggcatcctggcagccgtg caggtcggcggtgccctggcagccaacccccacagcccctctgtaggcctctggtgccct gtgttctttgtctacatcacctacacgctcctacccatccgcatgcgggcagctgtcttc agcggcctgggcctctccaccctgcatttgatcttggcctggcaactcaaccgtggtgac gccttcctctggaagcagctcggtgccaacatgatgctgttcctctgcaccaacgtcatc ggcatctgcacacactacccagctgaggtgtctcagcgccaggcctttcaggagacccgc ggttatatccaggcccggttgcacctgcagcatgagaatcggcagcaggagcggctgctg ctgtcggtgttgccccagcacgttgccatggagatgaaagaagacatcaacacaaagaaa gaagacatgatgttccacaagatctacatccagaagcatgacaatgtcagcatcctgttt gcggacattgaaggcttcaccagcctggcatcccagtgtactgcacaggagctggtcatg accctgaatgagctctttgcccgctttgacaagctggctgcggaaaatcattgcctgagg atcaagatcttaggggactgttattactgtgtgtcagggctgccagaggcccgggcagac cacgcccactgctgtgtggagatgggggtggacatgattgaggccatctcgctggtacgt gaggtgacaggtgtgaatgtgaacatgcgcgtgggcatccacagtgggcgcgtgcactgc ggtgtccttggcctgcggaaatggcagttcgatgtgtggtccaatgatgtgactttggcc aaccacatggaagctgggggccgggctggccggatccacatcactcgagccacactgcag tacctgaatggggactatgaggtggagccgggccgtggtggcgagcgcaatgcatacctc aaggagcagcacatcgagaccttcctcatcctgggagccagccagaaacggaaggaggag aaggccatgctggccaagctgcagcgaacgcgggccaactccgtggaagggctgatgcca cgctgggtgcctgaccgtgccttctcccgggccaaggactccaaagctttccgccagatg ggcattgatgattccagcaaagacaaccggggtgctcaagatgccctgaaccctgaggat gaggtagacgaattcctgggccgtgccattgatgcccgcagcatcgatcagctgcgcaag gaccatgtgcgccgtttcctgctcaccttccagagagaggaccttgaaaagaagtactcg cggaaggtggacccccgcttcggagcctatgtggcctgtgccctgttggtgttctgcttc atctgcttcatccagctcctcatcttcccacattcaaccctgatgcttgggatctatgcc agtatcttcttgctgttgctgatcactgtgctgacctgtgccgtgtactcctgtggctct ctcttccctaaggcgctgcaacgtctgtcgcgcagcattgtccgctcgcgggcacacagc accgtggttggcatcttttcagtcctgcttgtgttcacctccgccatcgccaacatgttc acctgtaaccacaccccaatacggacctgcgcagcccggatgctgaatttaacacctgcc gacatcactgcctgccacctgcagcaactcaattactctctgggcctggatgctcccctc tgtgaggacaccgcacctacctgcagcttccctgagtacttggtcgggaacatgctgctg agtctcttggccagctctgtcttcctgcacatcagtagcatcgggaagttggccatgatc tttgtcctggggctcatctacttggtgctgcttctgctgggtcccccagccaccatcttt gacaactatgacctgctgcttggcgtccatggcttggcttcttccaatgagaccttcgat gggctggactgcccagctgcagggagggtggcactcaaatacatgactcccgtgattctg ctggtgttcgcgctggcgctctatctgcatgcccagcaggtggaatcaactgcccgcctg gacttcctctggaaactgcaggcaacaggggagaaggaggagatggaggagctccaggca tacaaccggcggctgctgcataacattctgcccaaggacgtggctgcccacttcctggcc cgggagcgccggaacgatgaactctactatcagtcttgtgagtgtgtggctgtcatgttc gcctccattgccaacttctctgagttctacgtggagctggaggcaaacaatgagggcgtc gagtgcttgcggctgctcaatgagatcattgctgactttgatgagatcatcagcgaggag cggttccggcagctggagaagatcaagacgattggtagcacctacatggctgcctccggg ctgaacgccagcacctatgatcaggtgggccgctcccacatcactgccctcgccgactat gccatgcggctcatggagcagatgaagcacatcaatgagcactccttcaacaatttccag atgaagattgggctgaacatgggcccagttgtggcaggcgtcattggggctcggaagccg cagtatgacatctgggggaacacagtgaatgtctctagccgtatggacagcacgggggtc cctgaccgaattcaggtgaccacggacctgtaccaggttctagctgccaagggctaccag ctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctacttcctc aatgggggccccagcagttag

Equus caballus (horse): 100054305 Help Entry 100054305         CDS       T01058                                  Gene name ADCY4 Definition (RefSeq) adenylate cyclase type 4 isoform X1   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism ecb  Equus caballus (horse) Pathway ecb00230   Purine metabolism ecb01100   Metabolic pathways ecb01522   Endocrine resistance ecb04015   Rap1 signaling pathway ecb04020   Calcium signaling pathway ecb04022   cGMP-PKG signaling pathway ecb04024   cAMP signaling pathway ecb04062   Chemokine signaling pathway ecb04072   Phospholipase D signaling pathway ecb04114   Oocyte meiosis ecb04211   Longevity regulating pathway ecb04213   Longevity regulating pathway - multiple species ecb04261   Adrenergic signaling in cardiomyocytes ecb04270   Vascular smooth muscle contraction ecb04371   Apelin signaling pathway ecb04540   Gap junction ecb04611   Platelet activation ecb04713   Circadian entrainment ecb04714   Thermogenesis ecb04723   Retrograde endocannabinoid signaling ecb04724   Glutamatergic synapse ecb04725   Cholinergic synapse ecb04727   GABAergic synapse ecb04742   Taste transduction ecb04750   Inflammatory mediator regulation of TRP channels ecb04911   Insulin secretion ecb04912   GnRH signaling pathway ecb04913   Ovarian steroidogenesis ecb04914   Progesterone-mediated oocyte maturation ecb04915   Estrogen signaling pathway ecb04916   Melanogenesis ecb04918   Thyroid hormone synthesis ecb04921   Oxytocin signaling pathway ecb04923   Regulation of lipolysis in adipocytes ecb04925   Aldosterone synthesis and secretion ecb04926   Relaxin signaling pathway ecb04927   Cortisol synthesis and secretion ecb04928   Parathyroid hormone synthesis, secretion and action ecb04934   Cushing syndrome ecb04935   Growth hormone synthesis, secretion and action ecb04970   Salivary secretion ecb04971   Gastric acid secretion ecb04972   Pancreatic secretion ecb04976   Bile secretion ecb05032   Morphine addiction ecb05163   Human cytomegalovirus infection ecb05166   Human T-cell leukemia virus 1 infection ecb05200   Pathways in cancer ecb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ecb00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100054305 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100054305 (ADCY4)    04371 Apelin signaling pathway     100054305 (ADCY4)    04020 Calcium signaling pathway     100054305 (ADCY4)    04072 Phospholipase D signaling pathway     100054305 (ADCY4)    04024 cAMP signaling pathway     100054305 (ADCY4)    04022 cGMP-PKG signaling pathway     100054305 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100054305 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     100054305 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100054305 (ADCY4)    04062 Chemokine signaling pathway     100054305 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     100054305 (ADCY4)    04923 Regulation of lipolysis in adipocytes     100054305 (ADCY4)    04912 GnRH signaling pathway     100054305 (ADCY4)    04913 Ovarian steroidogenesis     100054305 (ADCY4)    04915 Estrogen signaling pathway     100054305 (ADCY4)    04914 Progesterone-mediated oocyte maturation     100054305 (ADCY4)    04921 Oxytocin signaling pathway     100054305 (ADCY4)    04926 Relaxin signaling pathway     100054305 (ADCY4)    04935 Growth hormone synthesis, secretion and action     100054305 (ADCY4)    04918 Thyroid hormone synthesis     100054305 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     100054305 (ADCY4)    04916 Melanogenesis     100054305 (ADCY4)    04925 Aldosterone synthesis and secretion     100054305 (ADCY4)    04927 Cortisol synthesis and secretion     100054305 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100054305 (ADCY4)    04270 Vascular smooth muscle contraction     100054305 (ADCY4)   09154 Digestive system    04970 Salivary secretion     100054305 (ADCY4)    04971 Gastric acid secretion     100054305 (ADCY4)    04972 Pancreatic secretion     100054305 (ADCY4)    04976 Bile secretion     100054305 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     100054305 (ADCY4)    04727 GABAergic synapse     100054305 (ADCY4)    04725 Cholinergic synapse     100054305 (ADCY4)    04723 Retrograde endocannabinoid signaling     100054305 (ADCY4)   09157 Sensory system    04742 Taste transduction     100054305 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     100054305 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     100054305 (ADCY4)    04213 Longevity regulating pathway - multiple species     100054305 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     100054305 (ADCY4)    04714 Thermogenesis     100054305 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100054305 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     100054305 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100054305 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100054305 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100054305 (ADCY4)    05163 Human cytomegalovirus infection     100054305 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100054305 (ADCY4) Enzymes [BR:ecb01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100054305 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N Motif Other DBs NCBI-GeneID:  100054305 NCBI-ProteinID:  XP_005603310 Ensembl:  ENSECAG00000013004 VGNC:  15089 UniProt:  F6ZH58 LinkDB All DBs Position 1 AA seq 1077 aa AA seqDB search MARLFSPRPQPSEDLFYETYYSLSQQYPLLLMLLAIVLCALLALLAVAWASGRELASDTG FLTTVLCALGGFSLLLGLASREHRLQRWTRPLSGLVWAALLALGYSFLFTGGVVSAWDQV SFFLFVIFTVYAMLPLGMRDATAAGLASSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAQEMK AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG AYAVEDAAMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR YLESWGAAKPFAHLSHVESPVSTSTPLPEKALASFSPQWSLDRSRTPRGLDEELDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFKYYTACTFLVFLSIFI VQMLVTNRPPALAITYSITFLLFLLLLFICFSEHLTRCVLKGPKVLHWLPALSGLVSTRP GLRVALGTATILLVFAMAITSLFFLPPASKCPFQAPNVSSMALNLSWELPGSLPLISIPY SMHCCVLGFLSCSLFLHMSFELKLLLLLLWLTASCSLFLHSHAWLSDCLIARLYLGPADS RPGVLKEPKMMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMV EFTVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETARALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGPPSAALG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagtccccggccgcagcccagcgaagacctcttctacgagacctac tacagcctgagccagcagtacccactgctgctaatgctgctggccatcgtgctctgcgcg ctcctggcgctgctcgcggtcgcctgggccagtggcagggagctggcctctgacacgggc ttcctgaccactgtgctgtgcgcgttgggcggcttctcgttgctgctgggcttggcttcc cgcgagcaccgactgcagcgctggacgcgtcccctgtccggcctcgtgtgggcagcgctg cttgcgctaggctacagcttcctgttcaccgggggcgtggtgagcgcctgggaccaggta tcctttttcctctttgtcatcttcacggtctatgccatgctgcccttgggcatgcgggac gccaccgccgcgggcctcgcctcctcactctcacatctgctggttcttgggctgtatctt gggcctcaacccgactctaggcccgcgctgctgcctcagctggcagcaaacgcggtattg ttcctgtgcgggaacgtggctggagcgtaccacaaggcgctgatggagcgcgccctgcgc gccacgttccgggaggcgctgagttccctgcactcgcgccggcggctggacaccgagaag aagcaccaggaacaccttctcttgtccatccttcctgcctacttggcccaagagatgaag gcagagatcatggcacggctgcaggctggacaggggtcacggccagagagcaccaacaac ttccatagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg ggcttcacgaggctggccagtgagtgctcccctaaagagttggtgctcatgctcaacgag ctctttggcaagttcgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctg ggagactgttactactgtgtctccgggctgccactctcgctgccagaccacgccatcaac tgcgtgcgcatggggctggacatgtgccgggccatcaggaaacttcgggcagccactggt gtggacatcaacatgcgtgtgggtgtgcactcaggcagcgtgctctgcggagtcatcggg ctgcagaagtggcagtacgatgtctggtcgcatgacgtcacactggccaaccacatggag gccggtggcgtgccagggcgcgtacatatcacaggggctaccctggccctgctggcaggg gcttatgctgtggaggatgcagccatggaacaccgagacccgtaccttcgggagctaggg gagcctacctacctggtcatcgatccccgggctgaggaagaggatgagaagggcactgca ggagggttgctgtcctctcttgagggccccaagatgcgtccatcactgctgatgacccgc tacctggagtcctggggtgcagccaagccttttgcccacctgagccacgtagagagccca gtgtccacctccactcctctcccggagaaggccctggcttccttcagcccccagtggagc ctggaccggagccgtaccccccggggactagatgaggaattggacaccggggatgccaag ttcttccaggtcattgaacagctcaactctcagaaacagtggaagcagtcgaaggacttc aacccactgacactgtacttccgagagaaggagatggagaaagagtatcgactctctgca ctccccgccttcaaatactacacagcctgcaccttcctggtttttctctccatcttcatc gtccagatgctggtgacaaacaggcccccagctctggccatcacctatagtatcaccttc ctcctcttcctcctcctcctcttcatctgtttctcagagcacctgacgaggtgtgtcttg aaaggccccaaggtgctacactggctgcctgcactgtctggcctggtgtccacacggccc ggactgcgagtcgccctgggcaccgccaccatccttctcgtcttcgccatggccattacc agcctgttcttcttaccgccagcatcgaagtgccctttccaggctcccaatgtgtcctcc atggctttgaacctctcctgggagctccctgggtccctgcctctcatcagcatcccatac tccatgcactgctgcgtgctgggtttcctctcctgctccctctttctgcacatgagcttc gaactgaagctgctgctgctcctgctgtggctgacggcctcctgctccctcttcttgcac tcccacgcctggctgtctgactgcctcatcgcccgcctctatctgggccccgcggattcc aggccaggggtgctgaaggagcccaaaatgatgggcgctatctccttcttcatcttcttc tttaccctccttgtcctggctcggcagaatgaatattactgccgcctggacttcctgtgg aagaagaagctgaggcaggagcgggaggagacagagacaatggagaacctgacccggctg ctcttggagaatgtgctccctgcgcacgtggccccccagttcattggccagaaccggcgc aacgaggatctctaccaccagtcgtacgagtgtgtttgtgtcctcttcgcctccgtccca gacttcaaggagttttactctgaatccaatatcaaccacgagggcctagagtgtctgcgg ctgctcaatgagataattgctgattttgatgagctgctctccaagcccaaattcagtggc gtggagaagatcaaaaccattggcagcacctacatggcagctacaggcttaaatgccacc tctggacaggacgcacagcaggatgctgagcgaagttgcagccaccttggcaccatggtg gaattcacggtggccctcgggtctaagctagatgtcatcaacaagcactcattcaacaac ttccgcttgcgtgtgggattgaaccacggaccagtagtggctggagtgattggggcccag aagccacaatacgacatctggggcaacacggtgaacgtggccagccgcatggagagtaca ggagtcctgggcaagatccaagtgactgaagagacagctcgggccctgcagtctttaggc tacacctgctacagccggggtgtcatcaaggtcaaaggcaaagggcagctctgcacctac ttcctgaacacagatttgacacgaactggacctccctctgccgccctgggctga

Equus caballus (horse): 100055961 Help Entry 100055961         CDS       T01058                                  Gene name ADCY3 Definition (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism ecb  Equus caballus (horse) Pathway ecb00230   Purine metabolism ecb01100   Metabolic pathways ecb01522   Endocrine resistance ecb04015   Rap1 signaling pathway ecb04020   Calcium signaling pathway ecb04022   cGMP-PKG signaling pathway ecb04024   cAMP signaling pathway ecb04062   Chemokine signaling pathway ecb04072   Phospholipase D signaling pathway ecb04114   Oocyte meiosis ecb04211   Longevity regulating pathway ecb04213   Longevity regulating pathway - multiple species ecb04261   Adrenergic signaling in cardiomyocytes ecb04270   Vascular smooth muscle contraction ecb04371   Apelin signaling pathway ecb04540   Gap junction ecb04611   Platelet activation ecb04713   Circadian entrainment ecb04714   Thermogenesis ecb04723   Retrograde endocannabinoid signaling ecb04724   Glutamatergic synapse ecb04725   Cholinergic synapse ecb04727   GABAergic synapse ecb04740   Olfactory transduction ecb04750   Inflammatory mediator regulation of TRP channels ecb04911   Insulin secretion ecb04912   GnRH signaling pathway ecb04913   Ovarian steroidogenesis ecb04914   Progesterone-mediated oocyte maturation ecb04915   Estrogen signaling pathway ecb04916   Melanogenesis ecb04918   Thyroid hormone synthesis ecb04921   Oxytocin signaling pathway ecb04923   Regulation of lipolysis in adipocytes ecb04925   Aldosterone synthesis and secretion ecb04926   Relaxin signaling pathway ecb04927   Cortisol synthesis and secretion ecb04928   Parathyroid hormone synthesis, secretion and action ecb04934   Cushing syndrome ecb04935   Growth hormone synthesis, secretion and action ecb04962   Vasopressin-regulated water reabsorption ecb04970   Salivary secretion ecb04971   Gastric acid secretion ecb04972   Pancreatic secretion ecb04976   Bile secretion ecb05032   Morphine addiction ecb05163   Human cytomegalovirus infection ecb05166   Human T-cell leukemia virus 1 infection ecb05200   Pathways in cancer ecb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ecb00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100055961 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100055961 (ADCY3)    04371 Apelin signaling pathway     100055961 (ADCY3)    04020 Calcium signaling pathway     100055961 (ADCY3)    04072 Phospholipase D signaling pathway     100055961 (ADCY3)    04024 cAMP signaling pathway     100055961 (ADCY3)    04022 cGMP-PKG signaling pathway     100055961 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100055961 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     100055961 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100055961 (ADCY3)    04062 Chemokine signaling pathway     100055961 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     100055961 (ADCY3)    04923 Regulation of lipolysis in adipocytes     100055961 (ADCY3)    04912 GnRH signaling pathway     100055961 (ADCY3)    04913 Ovarian steroidogenesis     100055961 (ADCY3)    04915 Estrogen signaling pathway     100055961 (ADCY3)    04914 Progesterone-mediated oocyte maturation     100055961 (ADCY3)    04921 Oxytocin signaling pathway     100055961 (ADCY3)    04926 Relaxin signaling pathway     100055961 (ADCY3)    04935 Growth hormone synthesis, secretion and action     100055961 (ADCY3)    04918 Thyroid hormone synthesis     100055961 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     100055961 (ADCY3)    04916 Melanogenesis     100055961 (ADCY3)    04925 Aldosterone synthesis and secretion     100055961 (ADCY3)    04927 Cortisol synthesis and secretion     100055961 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100055961 (ADCY3)    04270 Vascular smooth muscle contraction     100055961 (ADCY3)   09154 Digestive system    04970 Salivary secretion     100055961 (ADCY3)    04971 Gastric acid secretion     100055961 (ADCY3)    04972 Pancreatic secretion     100055961 (ADCY3)    04976 Bile secretion     100055961 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     100055961 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     100055961 (ADCY3)    04727 GABAergic synapse     100055961 (ADCY3)    04725 Cholinergic synapse     100055961 (ADCY3)    04723 Retrograde endocannabinoid signaling     100055961 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     100055961 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     100055961 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     100055961 (ADCY3)    04213 Longevity regulating pathway - multiple species     100055961 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     100055961 (ADCY3)    04714 Thermogenesis     100055961 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100055961 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     100055961 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100055961 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100055961 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100055961 (ADCY3)    05163 Human cytomegalovirus infection     100055961 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100055961 (ADCY3) Enzymes [BR:ecb01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100055961 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N NCE101 Motif Other DBs NCBI-GeneID:  100055961 NCBI-ProteinID:  XP_023475169 Ensembl:  ENSECAG00000008344 VGNC:  15088 LinkDB All DBs Position 15 AA seq 1143 aa AA seqDB search MPRNQGFSDPEYSAEYSAEYSVSLPSDPDRRVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLVVAGIGLVLDLI LFVLCKKGLLPDRVTRRVVPYLLWLLLTAQIFSYLGLNFSRAHAASDTVGWQAFFVFSFF ITLPLSLSPIVIISVVSCGVHTLVLGVTVAQQQQDGLKGMQLLREILANVFLYLCAIIVG VMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCD YLEEKGIETYLIIASKPEVKKTATQNGLNGSALPNGAPTSSKPSSPALIETKEPNGSVHT SGSTSEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVGASEDEHELNQLLSEALLERESA QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCAALVEILIDPWLMTN YVTFVVGEVLLLVLTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYYTGPNNSTMGMEVDDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLVTGAVAVINIYAWRPIFDEYDHKRFQEHELIALEKMQVFSTPGLNGTDRLPLVPSKYS MTVMVFIMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVA RHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDS LLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKEEKSDKERWQHLADLADFAL AMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMG NIQVVEETQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPAAFPNGSSVTLPHQVV DNS NT seq 3432 nt NT seq  +upstreamnt  +downstreamnt atgccgaggaaccagggcttctccgaccctgagtactctgctgagtactcggctgagtac tctgtcagcctgccctctgaccctgaccgcagggtgggccggacccatgaaatctctgtc cggaactcgggctcctgcctctgcctgcctcgcttcatgcggctgaccttcgtgcccgag tccttggagaacctgtaccagacctacttcaagaggcagcgccacgagaccctgctggtg ctggtggtcttcgcagccctcttcgactgctacgtggtggtcatgtgtgcagtggtcttc tccagcgacaagctggctcccctggtcgtggccgggatcggcctggtgttggacctcatc ctcttcgtgctctgcaaaaaggggctgctccccgaccgggtcacccggagagtggtgccc tacctgctgtggctgctgctaacagctcagatcttctcctacctgggcctgaacttctcc cgcgcccacgcggccagcgacacggtgggctggcaggcgttctttgtcttctccttcttc atcacgctgcccctcagcctcagccccatcgtcatcatctctgtggtctcctgtggcgtg cacacgctcgtcctcggggtcactgtggcccagcaacagcaggatgggctgaaggggatg cagttgctgagggagatcctggccaacgtcttcctctacctgtgcgccatcatcgtgggc gtcatgtcctactacatggcggaccgcaagcaccgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaaccttatgctt tccatcctgcccaagcacgtggccgacgagatgctaaaggacatgaagaaggacgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccgccatgagaacgtcagcatc ctctttgcggacatcgtgggcttcacccagctgtcgtctgcctgcagtgcccaggagctc gtgaaactgctcaacgagctctttgcccgcttcgacaagctggcagccaaataccaccag ctgcggattaagatcctgggcgactgttactactgcatctgtggcctgccggactaccgg gaggaccacgctgtctgctccatcctcatggggctcgccatggtggaggccatctcgtac gtgcgggagaagacgaagactggggtggacatgcgtgtgggggtgcacacgggcactgtg ctggggggcgtcctgggccagaagcgctggcagtacgacgtgtggtccactgacgtcact gtggccaacaagatggaggctggcggcatccctgggcgcgtgcacatctcccagagcacc atggactgcctgaaaggagagtttgacgtggagccaggcgacgggggcagccgctgcgat tacctagaagagaagggcatcgaaacctacctcatcatcgcgtccaagccggaagtgaag aaaacagccacccaaaatggcctcaacggctcggccctcccaaatggagcaccaacttct tcaaagcccagctcccctgccctcattgagaccaaggaacccaatgggagtgtccacacc agcggttccacatctgaggagcccgaagagcaagatgcccaggctgacaacccctccttc cccaatcctcgccggaggctgcgccttcaggacctggccgatcgagtggtgggtgcctct gaggacgagcatgaactcaaccagctgctcagtgaggcgctgctcgagcgcgagtctgcc caggtagtgaagaagagaaacacctttctcctatccatgcggttcatggaccctgagatg gaaacccgctactcggtggagaaggaaaagcagagtggggctgccttcagctgctcctgc gttgtcctgctctgtgcggccctggtcgagatactcattgacccttggctaatgacaaac tatgtgacctttgtggttggggaggttctgcttctggtcctgacaatctgctcgctggct gctatctttccccgggcctttcctaagaagctcgtggccttctcaacatggatcgaccgg acccgctgggccaggaacacctgggccatgttagccatcttcattttggttatggccaac gttgtggacatgcttagctgtctccagtactacactggacccaacaacagcaccatgggg atggaggtggacgatggctgcgtggagaaccccaagtattacaactatgtcgctgtgctg tctctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacactcatg ctgctcgtcacgggtgctgtggccgtcatcaacatctatgcctggcgccccatctttgat gaatatgaccacaaacgttttcaggaacatgaattgattgccttagagaagatgcaagtg ttttccacccctgggctcaatggcactgacaggctccccctggtgccttctaagtactcg atgacagtgatggtcttcatcatgatgctgagcttttactacttctcccgccacgtggaa aaactggcacggacactgttcttgtggaagattgaggtccatgaccagaaggaacgtgtc tatgagatgcgacgctggaacgaggccttggtcaccaacatgttgcctgagcacgtggca cgccatttcctggggtccaagaagagagatgaggagctgtacagccagtcttacgatgag attggagtcatgtttgcctccctgcccaactttgctgacttctacacagaggagagcatc aataatggcggcatcgagtgtctgcgcttcctcaatgagatcatctcagactttgactct ctcctggacaatcctaaattccgggtcatcaccaagatcaaaaccattggcagcacctat atggcagcttcaggagtcaccccagatgtcaacaccaacggctttaccagctccaacaag gaggaaaagtcggacaaggagcgctggcagcacctggctgatctggctgactttgcatta gccatgaaggatacacttacaaacatcaacaaccagtccttcaacaatttcatgctgcgt ataggcatgaacaaaggaggggtactggctggggtcattggagcccggaaaccgcactat gacatctggggcaatacagtcaacgtagccagcaggatggagtccacaggggtcatgggc aacattcaggtggtggaagaaacacaagccatccttcgagagtacggcttccgatttgtg aggcgagggcccatctttgtgaaagggaagggggagctgctgacctttttcttgaaggga cgtgacaagccagctgccttccctaacggctcctctgttacactgccccaccaggtggta gacaactcctga

Equus caballus (horse): 100057796 Help Entry 100057796         CDS       T01058                                  Gene name ADCY8 Definition (RefSeq) adenylate cyclase type 8 isoform X1   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism ecb  Equus caballus (horse) Pathway ecb00230   Purine metabolism ecb01100   Metabolic pathways ecb01522   Endocrine resistance ecb04015   Rap1 signaling pathway ecb04020   Calcium signaling pathway ecb04022   cGMP-PKG signaling pathway ecb04024   cAMP signaling pathway ecb04062   Chemokine signaling pathway ecb04072   Phospholipase D signaling pathway ecb04114   Oocyte meiosis ecb04211   Longevity regulating pathway ecb04213   Longevity regulating pathway - multiple species ecb04261   Adrenergic signaling in cardiomyocytes ecb04270   Vascular smooth muscle contraction ecb04371   Apelin signaling pathway ecb04540   Gap junction ecb04611   Platelet activation ecb04713   Circadian entrainment ecb04714   Thermogenesis ecb04720   Long-term potentiation ecb04723   Retrograde endocannabinoid signaling ecb04724   Glutamatergic synapse ecb04725   Cholinergic synapse ecb04727   GABAergic synapse ecb04742   Taste transduction ecb04750   Inflammatory mediator regulation of TRP channels ecb04911   Insulin secretion ecb04912   GnRH signaling pathway ecb04913   Ovarian steroidogenesis ecb04914   Progesterone-mediated oocyte maturation ecb04915   Estrogen signaling pathway ecb04916   Melanogenesis ecb04918   Thyroid hormone synthesis ecb04921   Oxytocin signaling pathway ecb04923   Regulation of lipolysis in adipocytes ecb04925   Aldosterone synthesis and secretion ecb04926   Relaxin signaling pathway ecb04927   Cortisol synthesis and secretion ecb04928   Parathyroid hormone synthesis, secretion and action ecb04934   Cushing syndrome ecb04935   Growth hormone synthesis, secretion and action ecb04970   Salivary secretion ecb04971   Gastric acid secretion ecb04972   Pancreatic secretion ecb04976   Bile secretion ecb05032   Morphine addiction ecb05163   Human cytomegalovirus infection ecb05166   Human T-cell leukemia virus 1 infection ecb05200   Pathways in cancer ecb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ecb00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100057796 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100057796 (ADCY8)    04371 Apelin signaling pathway     100057796 (ADCY8)    04020 Calcium signaling pathway     100057796 (ADCY8)    04072 Phospholipase D signaling pathway     100057796 (ADCY8)    04024 cAMP signaling pathway     100057796 (ADCY8)    04022 cGMP-PKG signaling pathway     100057796 (ADCY8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100057796 (ADCY8)   09144 Cellular community - eukaryotes    04540 Gap junction     100057796 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100057796 (ADCY8)    04062 Chemokine signaling pathway     100057796 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     100057796 (ADCY8)    04923 Regulation of lipolysis in adipocytes     100057796 (ADCY8)    04912 GnRH signaling pathway     100057796 (ADCY8)    04913 Ovarian steroidogenesis     100057796 (ADCY8)    04915 Estrogen signaling pathway     100057796 (ADCY8)    04914 Progesterone-mediated oocyte maturation     100057796 (ADCY8)    04921 Oxytocin signaling pathway     100057796 (ADCY8)    04926 Relaxin signaling pathway     100057796 (ADCY8)    04935 Growth hormone synthesis, secretion and action     100057796 (ADCY8)    04918 Thyroid hormone synthesis     100057796 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     100057796 (ADCY8)    04916 Melanogenesis     100057796 (ADCY8)    04925 Aldosterone synthesis and secretion     100057796 (ADCY8)    04927 Cortisol synthesis and secretion     100057796 (ADCY8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100057796 (ADCY8)    04270 Vascular smooth muscle contraction     100057796 (ADCY8)   09154 Digestive system    04970 Salivary secretion     100057796 (ADCY8)    04971 Gastric acid secretion     100057796 (ADCY8)    04972 Pancreatic secretion     100057796 (ADCY8)    04976 Bile secretion     100057796 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     100057796 (ADCY8)    04727 GABAergic synapse     100057796 (ADCY8)    04725 Cholinergic synapse     100057796 (ADCY8)    04720 Long-term potentiation     100057796 (ADCY8)    04723 Retrograde endocannabinoid signaling     100057796 (ADCY8)   09157 Sensory system    04742 Taste transduction     100057796 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     100057796 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     100057796 (ADCY8)    04213 Longevity regulating pathway - multiple species     100057796 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     100057796 (ADCY8)    04714 Thermogenesis     100057796 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100057796 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     100057796 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100057796 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100057796 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100057796 (ADCY8)    05163 Human cytomegalovirus infection     100057796 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100057796 (ADCY8) Enzymes [BR:ecb01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100057796 (ADCY8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N DUF1053 TBK1_ULD Motif Other DBs NCBI-GeneID:  100057796 NCBI-ProteinID:  XP_001916535 Ensembl:  ENSECAG00000024601 VGNC:  15092 UniProt:  F6R859 LinkDB All DBs Position 9 AA seq 1252 aa AA seqDB search MELSDVRCLSGSEELYTIHPTPPAGDGGSASRPQRLLWQTAVRHITEQRFIHGHRGSGGG GGSGGSGKASDPTGGGPNHHASQLSSDSALPLYSLGPGERAHSSGGTKVFPERSGSGSGS GSGGGGDLGFLHLDCAPSNSDFFLSGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRR KSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSH TYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGT SLLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEA RLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFAD VKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHA HCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANK LESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPE DIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALH VQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCA FIVLLFITAIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWIN ETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFT GVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKE ASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHV ARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFD ELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQHCEDKWGHLCALADFSLALTESIQEINK HSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLI LKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRMPGQYSLAAVVLGL VQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLTPSGPEPGTQAEGTDKSDLP NT seq 3759 nt NT seq  +upstreamnt  +downstreamnt atggagctctccgatgtgcgctgccttagcggcagcgaggaactctacaccatccacccg acgcccccggccggcgacggcgggagcgcctctcggccgcagcggctgctgtggcagacg gcggtgaggcacatcaccgagcagcgcttcattcacgggcaccggggcagcggcggcggc ggcggaagcggaggctccggcaaagcctcggaccctacaggcggcggccccaatcaccat gcgtcgcagctgtccagcgactccgcgctgcccctctactcgctgggccccggggagaga gcgcacagcagcggcggcaccaaagtcttcccggaacgcagcgggagcgggagcggcagc ggcagcgggggcgggggcgacctgggcttcctgcacctcgactgcgccccgagcaactcg gatttcttcctcagtgggggctatagctaccgaggggtcatttttcctaccctgcgcaac tccttcaagtcccgggatctggagcgcctctaccagcgctatttcctgggccagagacgc aaatctgaggtggtgatgaacgtgctggacgtgctcaccaaactcaccctcttggttctc cacttgagcctggcctcagcccccatggacccgctcaagggtatcctgctgggtttcttc actggcatcgaggtcgtgatttgcgccctggtggtggtcaggaaggacaccacctcgcac acgtacctgcaatacagcggcgtggtcacctgggtggccatgaccacccagatcctggca gcaggcctgggctacgggctcctgggtgatggcatcggctacgtgctctttacactcttc gccacctacagcatgctgccactgcccctcacctgggccatcctggccggcctgggcacc tcgctgctgcaggtcatcctccaagtggtcatcccccggctggcggtcatttccatcaac caggttgtggcccaggcagtgttattcatgtgtatgaacacagctggaatctttatcagt tacctgtcagaccgggcccagcgccaagccttcctggagacacggaggtgtgtggaggcc aggctgcgcctggaaacggaaaaccaaagacaggagcggctggtgctatctgtgctcccc cggtttgtcgtcctggaaatgatcaacgacatgaccaatgtggaagacgagcacctgcag caccagttccatcggatctacatccatcgctacgagaacgtcagtattctttttgcagat gttaaaggatttaccaacctctccacgaccttgtccgctcaggagctggtcaggatgctc aacgagctctttgccagatttgatcgactagcccatgagcatcactgccttcgcatcaaa atcctgggagactgctactactgtgtttccggacttcctgagccccgccaggaccacgcc cactgctgcgtggaaatgggcctcagcatgatcaaaaccatcaggtatgtacggtcaagg acaaagcatgatgttgacatgaggatcggaattcactcaggctcagtgctatgtggcgtt ttgggactacggaagtggcagtttgatgtctggtcttgggatgtggacattgcaaacaaa cttgaatctggaggaatcccggggaggattcacatttccaaagccacgctggactgtctc aacggtgactataacgtggaagagggtcacgggaaagagaggaacgaattcttgaggaag cataatatagagacctatttaattaagcagcctgaagagagtctgctgtccttgcccgaa gacattgtcaaggagtctgtgagctcctcagacaggagaaacagtggggcgacgttcacg gaaggatcttggagccccgaactgcccttcgataacatagtggggaaacagaacactctg gctgccctaacaagaaattcaataaatctacttccaaaccatcttgcacaagctttgcat gtccagtctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagt ggcgataaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagc ctggagcacaagtattctcaaatgagagatgaagtattcaagtcaaacttggtctgtgcg ttcatcgttcttctatttatcacggcaatacaaagtttgcttccttcttcaagggtgatg ccaatgaccatccagttttccatcctgattatgctgcactcagctctggtcctcatcacc acagcagaggactataagtgtttgcccctcgtcctccggaaaacttgctgttggattaac gagacttatttggcccggaatgtcatcatctttgcatccatcttgattaatttcctggga gccatcctaaatattctgtggtgtgattttgacaagtcgatacccttgaagaacctgact ttcaattcctcagctgtgtttacagatatctgctcctacccagagtactttgtcttcact ggggtgctggccatggtgacctgtgcggttttcctccgactgaactctgtcctgaagctg gccgtgctgctgatcatgatcgccatctacgccctgctgaccgagaccatctatgcaggt ctctttctgcgctacgacaacctgaaccacagtggagaagatttcctggggaccaaggag gcgtcgctgctgctgatggccatgttcctccttgctgtgttctaccacggacagcagctg gagtacacagcccgcctggacttcctttggcgagtacaggccaaagaggagatcaatgag atgaaggagctgagggaacacaatgagaacatgctccggaacatcttacccagtcacgtg gcccgccatttcctggagaaagaccgagacaatgaggagctgtattctcaatcctatgat gccgttggggtgatgttcgcctccatcccagggtttgcagacttttactctcagaccgaa atgaataaccaaggagtggaatgcctgcgcctcctgaatgagatcattgctgactttgat gagctgctcggcgaagaccggtttcaagacattgaaaaaattaagaccattggcagcacc tacatggctgtgtcaggcttgtcacctgaaaaacagcactgtgaagacaagtggggccat ctgtgtgctctggctgacttctccctcgccctgaccgaaagcatacaggagatcaacaag cattccttcaacaactttgaactccggattggcatcagccacggctcagtggtagctggt gtaattggcgctaagaaacctcagtatgacatttggggcaaaaccgtgaacctggcaagt cgaatggacagcacgggggtcagcggcaggatccaagtcccagaggagacctatctcatc ctgaaggaccagggctttgcctttgactaccgaggggagatctacgtgaaaggtatcagc gaacaggagggaaagatcaaaacgtactttctcctgggaagagtccagcccaacccgttc atcttgcccccgagaagaatgcccgggcagtactccttggccgcggtcgtcctgggcctc gtccagtccctcaacaggcaaaggcagaagcagctactcaacgagaacaacaacacgggc atcatcaagggccattacaaccggcggactttgttgacacccagtgggccagagcctgga acccaagccgaaggcaccgacaagtccgatttgccataa

Equus caballus (horse): 100058891 Help Entry 100058891         CDS       T01058                                  Gene name ADCY7 Definition (RefSeq) adenylate cyclase type 7 isoform X1   KO K08047   adenylate cyclase 7 [EC:4.6.1.1] Organism ecb  Equus caballus (horse) Pathway ecb00230   Purine metabolism ecb01100   Metabolic pathways ecb01522   Endocrine resistance ecb04015   Rap1 signaling pathway ecb04020   Calcium signaling pathway ecb04022   cGMP-PKG signaling pathway ecb04024   cAMP signaling pathway ecb04062   Chemokine signaling pathway ecb04072   Phospholipase D signaling pathway ecb04114   Oocyte meiosis ecb04211   Longevity regulating pathway ecb04213   Longevity regulating pathway - multiple species ecb04261   Adrenergic signaling in cardiomyocytes ecb04270   Vascular smooth muscle contraction ecb04371   Apelin signaling pathway ecb04540   Gap junction ecb04611   Platelet activation ecb04713   Circadian entrainment ecb04714   Thermogenesis ecb04723   Retrograde endocannabinoid signaling ecb04724   Glutamatergic synapse ecb04725   Cholinergic synapse ecb04727   GABAergic synapse ecb04750   Inflammatory mediator regulation of TRP channels ecb04911   Insulin secretion ecb04912   GnRH signaling pathway ecb04913   Ovarian steroidogenesis ecb04914   Progesterone-mediated oocyte maturation ecb04915   Estrogen signaling pathway ecb04916   Melanogenesis ecb04918   Thyroid hormone synthesis ecb04921   Oxytocin signaling pathway ecb04923   Regulation of lipolysis in adipocytes ecb04925   Aldosterone synthesis and secretion ecb04926   Relaxin signaling pathway ecb04927   Cortisol synthesis and secretion ecb04928   Parathyroid hormone synthesis, secretion and action ecb04934   Cushing syndrome ecb04935   Growth hormone synthesis, secretion and action ecb04970   Salivary secretion ecb04971   Gastric acid secretion ecb04972   Pancreatic secretion ecb04976   Bile secretion ecb05032   Morphine addiction ecb05163   Human cytomegalovirus infection ecb05166   Human T-cell leukemia virus 1 infection ecb05200   Pathways in cancer ecb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ecb00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100058891 (ADCY7)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100058891 (ADCY7)    04371 Apelin signaling pathway     100058891 (ADCY7)    04020 Calcium signaling pathway     100058891 (ADCY7)    04072 Phospholipase D signaling pathway     100058891 (ADCY7)    04024 cAMP signaling pathway     100058891 (ADCY7)    04022 cGMP-PKG signaling pathway     100058891 (ADCY7)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100058891 (ADCY7)   09144 Cellular community - eukaryotes    04540 Gap junction     100058891 (ADCY7)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100058891 (ADCY7)    04062 Chemokine signaling pathway     100058891 (ADCY7)   09152 Endocrine system    04911 Insulin secretion     100058891 (ADCY7)    04923 Regulation of lipolysis in adipocytes     100058891 (ADCY7)    04912 GnRH signaling pathway     100058891 (ADCY7)    04913 Ovarian steroidogenesis     100058891 (ADCY7)    04915 Estrogen signaling pathway     100058891 (ADCY7)    04914 Progesterone-mediated oocyte maturation     100058891 (ADCY7)    04921 Oxytocin signaling pathway     100058891 (ADCY7)    04926 Relaxin signaling pathway     100058891 (ADCY7)    04935 Growth hormone synthesis, secretion and action     100058891 (ADCY7)    04918 Thyroid hormone synthesis     100058891 (ADCY7)    04928 Parathyroid hormone synthesis, secretion and action     100058891 (ADCY7)    04916 Melanogenesis     100058891 (ADCY7)    04925 Aldosterone synthesis and secretion     100058891 (ADCY7)    04927 Cortisol synthesis and secretion     100058891 (ADCY7)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100058891 (ADCY7)    04270 Vascular smooth muscle contraction     100058891 (ADCY7)   09154 Digestive system    04970 Salivary secretion     100058891 (ADCY7)    04971 Gastric acid secretion     100058891 (ADCY7)    04972 Pancreatic secretion     100058891 (ADCY7)    04976 Bile secretion     100058891 (ADCY7)   09156 Nervous system    04724 Glutamatergic synapse     100058891 (ADCY7)    04727 GABAergic synapse     100058891 (ADCY7)    04725 Cholinergic synapse     100058891 (ADCY7)    04723 Retrograde endocannabinoid signaling     100058891 (ADCY7)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100058891 (ADCY7)   09149 Aging    04211 Longevity regulating pathway     100058891 (ADCY7)    04213 Longevity regulating pathway - multiple species     100058891 (ADCY7)   09159 Environmental adaptation    04713 Circadian entrainment     100058891 (ADCY7)    04714 Thermogenesis     100058891 (ADCY7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100058891 (ADCY7)   09165 Substance dependence    05032 Morphine addiction     100058891 (ADCY7)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100058891 (ADCY7)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100058891 (ADCY7)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100058891 (ADCY7)    05163 Human cytomegalovirus infection     100058891 (ADCY7)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100058891 (ADCY7) Enzymes [BR:ecb01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100058891 (ADCY7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N PsbI Motif Other DBs NCBI-GeneID:  100058891 NCBI-ProteinID:  XP_023492707 LinkDB All DBs Position 3 AA seq 1079 aa AA seqDB search MPAKGRYFLNEGEEDPDEHALYEKYRLTSQHGPLLLTLLLVAIAACVALIVITFSQGDPS RNPAVLGTVFLMLAVFVALYVLVYVECLVRRWLRASALLIWACLVTLGYVLVFDSWRKAA CAWQQVPFFLFVVFVVYTLLPFSMQGAIMVGVISSTSHLLVLGTVMEIFTKPSVSVGLQL LAVAVVFLCVNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH ISMGMKLAIIEKLKERGDRRCVPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCEAIKQ VREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT LNHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPKPKGDAALKMRA SVRMTRYLESWGAARPFAHLNHRESVSSSEPPVPSGRRPKAIPLRRHRTPDRSTSPKGRS EDDSYDDEMLSAIEGLSSTRPCCSTSDDFHACGFIFQEKGSEREYRLAPIPRARHYFACA SLVFVCILLVHVLLMPRMAALGVSFGLVACVLGLVLGLCFADEILRCCPAWGTLRAISER VETHPLLRLSLAVLTIGSLLTIAIVNLPLTPFPAMELPAGNETNLRSVSSREKALCELLL YYTCSCILAFVACSVFLRMSLELKVVLLTVALVAYLVLLNIAPCWQWGCCGHSLGNVTKT NSTLSSPSCSWRDLQTTINFALVLFYVTLALLSRQIDYYCRLDCLWKKKFKKEHEEFETM ENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKEG LECLRLLNEIVADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVPSGHDNQDLERQHAHI GIMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASR MESTGELGKIQVTEETSAILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKFQGLGPN NT seq 3240 nt NT seq  +upstreamnt  +downstreamnt atgccggccaaggggcgctacttcctcaacgagggcgaggaggacccggacgaacacgca ctctacgagaagtaccgcctcaccagccagcacgggccgctgctgctcacgctcctgctg gtggccatcgccgcctgcgttgcactcatcgtcatcaccttcagccagggggacccctcc agaaacccggctgtcctggggacagtattcttaatgctcgccgtgtttgtggctctctat gtgctggtgtatgtcgagtgcctcgtccggcggtggctcagggcctcagcactgctcatc tgggcctgccttgtgacgctgggctacgtgctggtgtttgactcgtggaggaaggcggcc tgtgcgtggcagcaggtgcccttcttcctgttcgttgtcttcgtggtgtacacactgctg cccttcagcatgcagggggccataatggtgggggtcatctccagcacctcccacctcctg gtgcttggcactgtcatggagatcttcacaaagcccagcgtcagcgtggggctgcagctg ctggctgttgccgttgtcttcctgtgcgtgaacctcacgggcgccttccataagcaccag atgcaggacgcctcccgtgacctcttcacctacactgtgaagtgcatccagatcaggcgt aagctgcgcattgagaagcgccagcaggagaacttgctgctgtcagtgctgccggcgcac atctccatgggcatgaagctggccatcatcgagaagctcaaggagcggggggaccgccgc tgtgtgccggacaacaacttccacagcctctacgtgaagcggcaccagaacgtcagcatc ctctacgctgacatcgtgggcttcacgcagctggccagcgactgttcccctaaggagctg gtggtggtgctgaacgagctcttcggcaagttcgaccagatcgccaaggccaatgagtgc atgcggatcaagatcctgggcgactgctactactgcgtgtcgggcctgcccgtgtccctg cccacccatgcccggaactgtgtgaagatggggctcgacatgtgcgaggccattaagcag gtgcgggaggccacgggcgtggacatcagcatgcgtgtgggtatacattcaggaaacgtg ctgtgtggtgttattgggctgcgcaagtggcagtacgacgtgtggtcccatgacgtgtcc ctggccaaccggatggaggcggctggagtccccggccgggtgcacatcacagaggcgacg ctgaaccacctggacaaggcgtacgaggtggaagatgggcacgggcagcagcgagacccc tacctgaaagagatgaacattcgcacctacctggtcatcgacccccggagccagcagcca cccccgcccagccaacacctccccaagcccaagggggatgcggccctgaagatgcgggcg tccgtgcgcatgacccgctacctcgagtcctggggggcggcacggcccttcgcacacctc aaccaccgcgagagcgtgagcagcagcgagcctcctgtccccagcgggcggaggcccaag gccattcccctgcggcgccatcggacccctgacagaagtacatcccccaaggggcggtct gaggacgactcctacgatgacgagatgctctcagccatcgaagggctcagctccaccagg ccctgctgctccacgtccgacgacttccatgcctgcgggttcatcttccaggagaagggc tccgagcgagagtaccgcctggcgcccatcccccgggcccgtcactactttgcctgtgcc agtctcgtcttcgtctgcatcctgctcgtccatgtcctgctgatgcccaggatggcagct ctgggcgtgtccttcgggctggtggcctgcgtgctggggttggtgctgggcctgtgcttt gctgacgagatcttgaggtgctgcccagcctgggggacactccgggccatctctgagagg gtggagacgcatcccctgctgcggctgtccctggctgtgctgaccatcggcagcctgctc accattgccatcgtcaacctgccgctgactccgttcccagccatggagctgcctgctggc aatgagacaaacctgaggtctgtgagcagcagggagaaggccctgtgcgagctcctcctg tattacacctgcagctgcatcctggcctttgtggcttgctctgttttcctgcggatgagc ctggagctgaaggtcgtgcttttgacagtggccttggtggcctacctggtgcttctcaac atcgccccatgctggcagtggggctgctgtggccacagcctgggcaacgtcaccaagacc aacagcaccctcagctccccttcctgctcgtggagggacctgcagacgacgatcaacttc gccctggttctgttttacgtcaccctcgccttgctgtcccgacagattgactattactgc cgcttggattgtttgtggaagaagaagttcaagaaggagcacgaggagtttgaaaccatg gagaacgtgaaccgcctgcttctggagaatgtgctgccagcccacgtggccgcccacttc attggtgacaagttaaacgaggactggtaccatcagtcgtacgactgcgtctgtgtcatg tttgcgtccgtgccagacttcaaagtgttctacactgagtgtgacgtcaacaaggaaggc ctggagtgtctgcgcctgctgaacgagattgtcgctgactttgacgagctcctgctaaag cccaagttcagtggtgtggagaagatcaagaccatcggcagcacgtacatggcagctgca gggctcagtgtcccctcagggcacgacaaccaggacctggagcgccagcatgcccacatt ggcatcatggtggagttcagcatcgccctgatgagcaagctggacggcatcaacaggcac tccttcaactccttccgcctccgagtcggcataaaccacgggcctgtgattgctggagtg atcggggcgcgaaaacctcagtatgacatctggggaaacacggttaacgttgccagccga atggagagcactggggaacttgggaaaatccaggttaccgaagagacaagtgccatcctc cagggactaggttattcttgtgaatgccgtggactgatcaacgtcaaaggcaaaggcgag ctgaggacttactttgtctgtacagacactgccaagtttcaagggctggggcccaactga

Equus caballus (horse): 100065563 Help Entry 100065563         CDS       T01058                                  Gene name ADCY1 Definition (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism ecb  Equus caballus (horse) Pathway ecb00230   Purine metabolism ecb01100   Metabolic pathways ecb01522   Endocrine resistance ecb04015   Rap1 signaling pathway ecb04020   Calcium signaling pathway ecb04022   cGMP-PKG signaling pathway ecb04024   cAMP signaling pathway ecb04062   Chemokine signaling pathway ecb04072   Phospholipase D signaling pathway ecb04114   Oocyte meiosis ecb04211   Longevity regulating pathway ecb04213   Longevity regulating pathway - multiple species ecb04261   Adrenergic signaling in cardiomyocytes ecb04270   Vascular smooth muscle contraction ecb04371   Apelin signaling pathway ecb04540   Gap junction ecb04611   Platelet activation ecb04713   Circadian entrainment ecb04714   Thermogenesis ecb04720   Long-term potentiation ecb04723   Retrograde endocannabinoid signaling ecb04724   Glutamatergic synapse ecb04725   Cholinergic synapse ecb04727   GABAergic synapse ecb04750   Inflammatory mediator regulation of TRP channels ecb04911   Insulin secretion ecb04912   GnRH signaling pathway ecb04913   Ovarian steroidogenesis ecb04914   Progesterone-mediated oocyte maturation ecb04915   Estrogen signaling pathway ecb04916   Melanogenesis ecb04918   Thyroid hormone synthesis ecb04921   Oxytocin signaling pathway ecb04923   Regulation of lipolysis in adipocytes ecb04925   Aldosterone synthesis and secretion ecb04926   Relaxin signaling pathway ecb04927   Cortisol synthesis and secretion ecb04928   Parathyroid hormone synthesis, secretion and action ecb04934   Cushing syndrome ecb04935   Growth hormone synthesis, secretion and action ecb04970   Salivary secretion ecb04971   Gastric acid secretion ecb04972   Pancreatic secretion ecb04976   Bile secretion ecb05032   Morphine addiction ecb05142   Chagas disease ecb05146   Amoebiasis ecb05163   Human cytomegalovirus infection ecb05166   Human T-cell leukemia virus 1 infection ecb05200   Pathways in cancer ecb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ecb00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100065563 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100065563 (ADCY1)    04371 Apelin signaling pathway     100065563 (ADCY1)    04020 Calcium signaling pathway     100065563 (ADCY1)    04072 Phospholipase D signaling pathway     100065563 (ADCY1)    04024 cAMP signaling pathway     100065563 (ADCY1)    04022 cGMP-PKG signaling pathway     100065563 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100065563 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     100065563 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100065563 (ADCY1)    04062 Chemokine signaling pathway     100065563 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     100065563 (ADCY1)    04923 Regulation of lipolysis in adipocytes     100065563 (ADCY1)    04912 GnRH signaling pathway     100065563 (ADCY1)    04913 Ovarian steroidogenesis     100065563 (ADCY1)    04915 Estrogen signaling pathway     100065563 (ADCY1)    04914 Progesterone-mediated oocyte maturation     100065563 (ADCY1)    04921 Oxytocin signaling pathway     100065563 (ADCY1)    04926 Relaxin signaling pathway     100065563 (ADCY1)    04935 Growth hormone synthesis, secretion and action     100065563 (ADCY1)    04918 Thyroid hormone synthesis     100065563 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     100065563 (ADCY1)    04916 Melanogenesis     100065563 (ADCY1)    04925 Aldosterone synthesis and secretion     100065563 (ADCY1)    04927 Cortisol synthesis and secretion     100065563 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100065563 (ADCY1)    04270 Vascular smooth muscle contraction     100065563 (ADCY1)   09154 Digestive system    04970 Salivary secretion     100065563 (ADCY1)    04971 Gastric acid secretion     100065563 (ADCY1)    04972 Pancreatic secretion     100065563 (ADCY1)    04976 Bile secretion     100065563 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     100065563 (ADCY1)    04727 GABAergic synapse     100065563 (ADCY1)    04725 Cholinergic synapse     100065563 (ADCY1)    04720 Long-term potentiation     100065563 (ADCY1)    04723 Retrograde endocannabinoid signaling     100065563 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100065563 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     100065563 (ADCY1)    04213 Longevity regulating pathway - multiple species     100065563 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     100065563 (ADCY1)    04714 Thermogenesis     100065563 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100065563 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     100065563 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100065563 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100065563 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100065563 (ADCY1)    05163 Human cytomegalovirus infection     100065563 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     100065563 (ADCY1)    05142 Chagas disease     100065563 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100065563 (ADCY1) Enzymes [BR:ecb01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100065563 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N DUF1053 HNOBA Motif Other DBs NCBI-GeneID:  100065563 NCBI-ProteinID:  XP_005614918 Ensembl:  ENSECAG00000025044 VGNC:  15086 LinkDB All DBs Position 4 AA seq 907 aa AA seqDB search MFGVFVRILAERSQRKSFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK PPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR RIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSF LKAHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFS NVMTCEDDDKRRALRTASEKLRNRSSFSANVVYTTPGTRVNRYISRLLEARQPELEMADL NFFTLKYKQAERERKYHQLQDEYFTSAVVLALALAALFSLVYLLIIPQNLAVLLLLVFSI CFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSSPNG SLVFLSSGGRSPVLPAPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLSVLTASYIL VLELSGYTKAVGGGTVSGRSFEPIVAILLFSCTLALHARQVDVKLRLDYLWAVQAEEERD DMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIEL DGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGAKAKKCI SSHLGTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVN VASRMDSTGVQGRIQVTEEVHRLLRRGAYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQ SRSLNSERKMYPYGRAGLQTRLATGHPPVPAVAGLPVTAGLGALQGSGIAPGPPGPPLPP GAAGKEA NT seq 2724 nt NT seq  +upstreamnt  +downstreamnt atgttcggcgtctttgtgaggatcctggccgagcgctcccagaggaagtccttcctgcag gcccgaaactgcatcgaggaccggctgcgactggaggacgagaatgagaagcaggagcgg ctgctcatgagtctcttgccccggaacgtcgccatggagatgaaggaggacttcctgaag ccccccgagaggattttccacaagatttacatccagcggcatgacaacgtgagcatcctc ttcgcagacatcgtgggcttcacgggcttggcgtctcagtgcacggcccaggagctggtg aaactcctcaacgagctcttcggcaagtttgatgaattggccacggagaaccactgccgc cgcatcaagatcctcggagactgttactactgcgtgtctggcctcacccagcccaagact gaccacgcccattgctgtgtggagatgggcctggacatgatcgacaccatcacgtccgtg gccgaggccaccgaggtggacctgaacatgcgtgtggggctgcacaccggcagggtcctc tgcggggtcctgggcctgcgcaagtggcagtatgatgtgtggtccaacgacgtgaccttg gccaatgtcatggaggccgccggcctgccggggaaggttcatatcacgaagaccaccctg gcgtgcttgaatggcgactacgaggtggaaccaggtcacggacacgagaggaacagtttt ctgaaagctcacaatatcgagaccttttttattgtgccatcgcatcggcgaaagatattt ccggggctgattctctcagacataaagccggccaagaggatgaagttcaagaccgtgtgc tacctgctggtgcagctcatgcactgccggaagatgttcaaggcggagatccccttctcc aacgtcatgacctgcgaggatgatgacaagcggagggctttgagaacagcctcggaaaaa ctcagaaaccgctcgtctttctctgcgaacgttgtgtacaccaccccgggcacgcgcgtc aataggtacatcagccgcctcctagaagcccgccagccagaactggagatggcagacctg aacttcttcaccctgaagtacaagcaagctgagcgagagcgaaagtaccaccagctccag gacgagtacttcaccagcgccgtcgtgctcgccctcgccctggccgccttattcagcctc gtctaccttctgatcatcccgcagaacttggctgtcctgctcctgctggtgttctccatc tgcttcctggtggcctgtgtcctgtacctgcacatcacccgggtccagtgttttccaggg tgcctgacgatccagattcgtaccgtcctgtgtattttcatagtggtcttaatctattct gtggcccaaggatgtgtggtgggctgtctgccctgggcctggagctccagtcccaacggg tctctggtgttcctgtcgtccggcggccggagcccagtgctgcctgccccgccctgcgag tctgcaccccacgccctgctctgtggcctggtgggcaccctcccgctggccatattcctg cgggtctcttccttgcccaaaatgatcctgctctccgtgctcacggcgtcctacatcctg gtcctggagctcagcgggtacaccaaggccgtggggggcggcactgtctctgggcgcagc ttcgagccgattgtggccatcctgctgttctcgtgcacgctggccctgcacgcccggcag gtggacgtcaagctgcggctggactacctctgggctgtgcaggcagaggaggagcgagac gacatggagcgggtgaagctggacaataagaggattctcttcaatctcctgccggcccac gtcgcccagcatttcctcatgtccaacccccggaacatggacctctactaccagtcgtac tcgcaggtgggcgtcatgttcgcctccatccccaacttcaacgacttctacatcgagctg gatggcaacaacatgggggtggagtgcctgcgcctcctgaacgagatcattgccgacttc gacgagctcatggacaaagacttttacaaggacctggagaagatcaagaccattgggagc acttatatggccgcggtgggattggcgcccacggctggggccaaggctaagaagtgtatc tcctcccacctcggcacgctggcggattttgccatcgagatgttcgacgtcctggatgag atcaactaccagtcttacaatgacttcgtgctccgtgtcggcatcaacgttggccccgtg gtggctggggtgattggggctcgcaggccgcagtatgacatctggggaaacactgtcaac gtggccagtcggatggacagcaccggggtccagggcagaatccaggtgacggaggaggtg caccggctgctgcggcggggtgcgtaccgtttcgtgtgccgaggcaaagtcagtgtcaag ggcaagggcgagatgctaacatacttcctggaaggcaggaccgacggaaatggctcccaa tccaggtccctgaactcggagcggaaaatgtatccttacggcagagctggcctccagacc agactggccacgggccacccccctgtgcccgccgtggctggcctcccggtcacagctggg ctgggggctctgcagggctcggggatcgcccctgggcctcccggcccacccctgccccct ggagcagctggaaaggaggcttag

Equus caballus (horse): 100066046 Help Entry 100066046         CDS       T01058                                  Gene name ADCY9 Definition (RefSeq) adenylate cyclase type 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism ecb  Equus caballus (horse) Pathway ecb00230   Purine metabolism ecb01100   Metabolic pathways ecb01522   Endocrine resistance ecb04015   Rap1 signaling pathway ecb04020   Calcium signaling pathway ecb04022   cGMP-PKG signaling pathway ecb04024   cAMP signaling pathway ecb04062   Chemokine signaling pathway ecb04072   Phospholipase D signaling pathway ecb04114   Oocyte meiosis ecb04211   Longevity regulating pathway ecb04213   Longevity regulating pathway - multiple species ecb04261   Adrenergic signaling in cardiomyocytes ecb04270   Vascular smooth muscle contraction ecb04371   Apelin signaling pathway ecb04540   Gap junction ecb04611   Platelet activation ecb04713   Circadian entrainment ecb04714   Thermogenesis ecb04723   Retrograde endocannabinoid signaling ecb04724   Glutamatergic synapse ecb04725   Cholinergic synapse ecb04727   GABAergic synapse ecb04750   Inflammatory mediator regulation of TRP channels ecb04911   Insulin secretion ecb04912   GnRH signaling pathway ecb04913   Ovarian steroidogenesis ecb04914   Progesterone-mediated oocyte maturation ecb04915   Estrogen signaling pathway ecb04916   Melanogenesis ecb04918   Thyroid hormone synthesis ecb04921   Oxytocin signaling pathway ecb04923   Regulation of lipolysis in adipocytes ecb04925   Aldosterone synthesis and secretion ecb04926   Relaxin signaling pathway ecb04927   Cortisol synthesis and secretion ecb04928   Parathyroid hormone synthesis, secretion and action ecb04934   Cushing syndrome ecb04935   Growth hormone synthesis, secretion and action ecb04961   Endocrine and other factor-regulated calcium reabsorption ecb04962   Vasopressin-regulated water reabsorption ecb04970   Salivary secretion ecb04971   Gastric acid secretion ecb04972   Pancreatic secretion ecb04976   Bile secretion ecb05032   Morphine addiction ecb05163   Human cytomegalovirus infection ecb05166   Human T-cell leukemia virus 1 infection ecb05200   Pathways in cancer ecb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ecb00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100066046 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100066046 (ADCY9)    04371 Apelin signaling pathway     100066046 (ADCY9)    04020 Calcium signaling pathway     100066046 (ADCY9)    04072 Phospholipase D signaling pathway     100066046 (ADCY9)    04024 cAMP signaling pathway     100066046 (ADCY9)    04022 cGMP-PKG signaling pathway     100066046 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100066046 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     100066046 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100066046 (ADCY9)    04062 Chemokine signaling pathway     100066046 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     100066046 (ADCY9)    04923 Regulation of lipolysis in adipocytes     100066046 (ADCY9)    04912 GnRH signaling pathway     100066046 (ADCY9)    04913 Ovarian steroidogenesis     100066046 (ADCY9)    04915 Estrogen signaling pathway     100066046 (ADCY9)    04914 Progesterone-mediated oocyte maturation     100066046 (ADCY9)    04921 Oxytocin signaling pathway     100066046 (ADCY9)    04926 Relaxin signaling pathway     100066046 (ADCY9)    04935 Growth hormone synthesis, secretion and action     100066046 (ADCY9)    04918 Thyroid hormone synthesis     100066046 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     100066046 (ADCY9)    04916 Melanogenesis     100066046 (ADCY9)    04925 Aldosterone synthesis and secretion     100066046 (ADCY9)    04927 Cortisol synthesis and secretion     100066046 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100066046 (ADCY9)    04270 Vascular smooth muscle contraction     100066046 (ADCY9)   09154 Digestive system    04970 Salivary secretion     100066046 (ADCY9)    04971 Gastric acid secretion     100066046 (ADCY9)    04972 Pancreatic secretion     100066046 (ADCY9)    04976 Bile secretion     100066046 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     100066046 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     100066046 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     100066046 (ADCY9)    04727 GABAergic synapse     100066046 (ADCY9)    04725 Cholinergic synapse     100066046 (ADCY9)    04723 Retrograde endocannabinoid signaling     100066046 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100066046 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     100066046 (ADCY9)    04213 Longevity regulating pathway - multiple species     100066046 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     100066046 (ADCY9)    04714 Thermogenesis     100066046 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100066046 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     100066046 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100066046 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100066046 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100066046 (ADCY9)    05163 Human cytomegalovirus infection     100066046 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100066046 (ADCY9) Enzymes [BR:ecb01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100066046 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF512 DUF1053 zf-C2HC_2 Complex1_LYR_1 AC_N Motif Other DBs NCBI-GeneID:  100066046 NCBI-ProteinID:  XP_001502298 Ensembl:  ENSECAG00000024355 VGNC:  15093 UniProt:  F6XFB9 LinkDB All DBs Position 13 AA seq 1353 aa AA seqDB search MASPPHQQLLQHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS AGVPRRVGVGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACMERCFPQTQRRFRYAL FYIGFACLLWSIYFGVHMRSKLIVMVAPALCFLVVCVGFFLFTFTKLYARHYVWTSLVLT LLVFALTLAAQFQVLTPLSGRVDSSNHTRAAKSTDTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLFLGVAYSVLFETFGYHFRDEDCFPSPGAGALHWELLSRALLHVCVHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGKVTERLGQSVVADQLKGLKTYLIAGQRAKESRCSCSEALLSGFEVIDGSRLS SGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAVQNGCQEEHKN STKASGGPNSKTQNGLLSPPQEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERNYRTSYQEEVIKNSPVKTF ASATFSSLLDVFLSTTVFLILSITCFLKYGAAAMPPPPAALAVFSTALLLEVLSLVVSVR MVFFLEDVMACTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHITSEFETNIHFTVFTGS AALIAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYISLCPDSSIVMSHLDAVQNFSSQR HPCNSSLLHDSRRPARLIGQEVALVFFLLLLLVWFLTREFEVSYRLHYHGDVEADLHRTT IQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKE CYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATRCQDGSHPQEHLQILFE FAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTT GVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCMDNGVVPHHQLSISP DIRVQVDGSIGRSPTDEIANLVPSVQNLDKTSLGSDNNTQAKDAHLSSKRPWKEPIKAEE RCRFGKAIEKSDCEEMGMEEANELTKLNVSKSV NT seq 4062 nt NT seq  +upstreamnt  +downstreamnt atggcttctccgccccaccagcagctgctgcagcaccacagcaccgaggtgagttgtgac tccagcggcgacagcaacagcgtgagggtcaaaatcaaccccaagcagctgtcctccaac agccaccccaaacactgcaagtacagcatctcctccagctgtagcagctccggggactcg gcgggggtcccccggagagtgggcgtcggaggccgcctgcgcaggcagaagaagctgccc cagctgttcgagagggcctccagccggtggtgggaccccaagttcgactcggtgaacctg gaggaggcttgcatggagcgctgcttcccgcagacgcagcgccgcttccggtatgcgctc ttctacatcggcttcgcctgccttctctggagcatctattttggggtccacatgagatcc aaactgattgtcatggtcgcccctgctctgtgcttcctcgtggtgtgtgtgggctttttt ctctttaccttcaccaagctgtatgcccggcattacgtgtggacctcgctggttctcacc ctcctggtgttcgccctgaccctggctgcccagtttcaggttttgacgcctctctcagga cgggttgacagctccaatcatacacgggcagccaagtccacagacacttgcttatctcaa gtggggagcttttccatgtgcatcgaagtgctctttttgctctacaccgtcatgcactta cctttgtacttgagcttgtttttgggagtggcgtattctgttctttttgagacctttggc tatcatttccgagatgaagattgtttcccctcgcctggggcaggggccctgcactgggag ctgctgagccgggccctgctccacgtctgcgttcacgccatcgggatccacctgttcatc atgtcccaggtgagatccagaagcaccttcctcaaggtgggacagtcaattatgcacggg aaggatctggaagtggaaaaagccctgaaagagaggatgattcattctgtgatgccaaga atcatagctgatgacctgatgaaacagggggatgaagagagcgagaattctgtcaaaagg catgccacctccagccccaagaacaggaagaaaaagtcttccatacagaaggcccctatt gcattccgcccgtttaagatgcagcagatcgaagaagtcagtattttatttgcagatatc gtgggcttcaccaagatgagtgccaacaagtctgctcacgccctggtgggtctcctcaat gatctcttcggtcgcttcgaccggttatgtgaagagaccaagtgtgagaaaatcagcacc ttgggggactgctactattgtgtggcagggtgccccgagccccgggccgaccatgcctac tgctgcatcgagatgggcttgggcatgataagagccattgagcagttctgccaggagaag aaggagatggtgaacatgcgcgttggggttcacacggggaccgtgttgtgcggcatcttg ggcatgaggaggtttaaatttgatgtgtggtccaatgacgtgaacttggccaatctcatg gagcagctgggagtggctggcaaggttcacatttctgaggccactgcaaaatacctagat gatcggtacgaaatggaagatgggaaggttactgaacgcctcggccagagtgttgttgcc gaccagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcgt tgcagctgttcagaggccttgctttctggctttgaggtcattgacggctcacggctgtcc tcaggccctaggggacaggggacagcatcgccagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacctgcccttcatgcggaatcacgtttgctcccaaa tcagaagctggtgcagaaggaggagcagtgcaaaatggctgtcaagaggagcataaaaac agtaccaaggcttctggaggacctaattccaaaacgcaaaacggacttctgagccctccc caggaagagaagctcaccaacagtcagacctccctgtgcgagatcttacaggaaaaggga aggtgggcaggtgtgagcttggaccagtcagctctccttccactgagattcaagaacatc cgggagaaaacagacgcccattttgttgatgttatcaaagaagacagcctgatgaaagat tatttttttaagccacccattaatcagttcagcttgaacttcctggatcaggagctagag cgaaactacaggaccagctatcaagaagaggttataaagaattctcccgtgaagactttt gccagtgccaccttcagctccctcctggatgtgtttctgtccacgacagtgtttctgatt ctctccatcacctgcttcctgaagtacggggccgccgccatgcctcccccgccggccgcc ctggccgtcttcagcactgccctgctgttggaggtgctgtccctcgtggtctccgtcagg atggtgtttttcctggaggatgtgatggcttgtaccaagcgcctgctagagtggatagcc ggctggctcccgcgccatttcatcggggccatcctggtgtccctccctgctctcgcagtc tattcacacatcacctctgaatttgagacaaacatacatttcaccgtgttcaccggctca gctgctctcatcgccgtcgtgcactattgtaacttctgccagctcagctcctggatgagg tcctccttggccaccgtcgtcggggcggggcccctgcttctgctctatatctccctctgt ccggacagttccatagtaatgtcacaccttgatgcagtacagaatttcagttcccagagg catccgtgcaatagttccttgctgcatgacagcaggagaccagcccgcctaattggccaa gaggtggctcttgtcttctttctcctgctcttgttggtctggttcctgacccgagaattc gaagtcagctaccgccttcactaccatggggacgtggaggcggaccttcaccgcaccacg atccagagcatgagggaccaagccgactggctgctgaggaacatcatcccctaccacgtg gccgagcagctgaaggtttcccagacctactccaagaaccatgacagcggaggagtcatc ttcgccagcatcgtcaacttcagtgagttctacgaggagaactacgagggaggcaaggag tgctaccgggtcctcaatgagctgatcggggacttcgacgagctcctgagcaagccagac tacagcagcatcgagaagatcaagaccatcggggccacatacatggcggcgtcggggctg aatgccacacggtgccaggacggtagccacccgcaggagcacctgcaaatcctgtttgag tttgccaaggagatgatgcgcgtggtggacgatttcaacaacaacatgctctggttcaac ttcaagctcagagttggcttcaaccatgggcccctcacagcaggggtcatcggcacgacc aagctgctgtacgacatctggggggacaccgtcaacatcgccagcaggatggacaccacg ggggtggagtgccgcatccaggtgagtgaagagagctaccgtgtcctaagcaagatgggc tacgactttgactacagagggacggtgaacgtaaaggggaaaggtcagatgaagacctac ctttacccaaagtgcatggacaacggggtcgtgccgcatcaccagctgtccatctcccca gacatccgagtccaggtggacggcagcatcggacggtctcccacggacgagattgccaac ctggtgccttctgtacagaacttggacaagacgtctctgggttctgataacaacacacag gccaaggatgctcacctgtcctctaagagaccctggaaagagcccatcaaagccgaagaa aggtgtcgatttggcaaagccatagagaagagcgactgtgaagaaatggggatggaagaa gccaacgagctcaccaagctcaacgtctcaaagagtgtgtga

Equus caballus (horse): 100070498 Help Entry 100070498         CDS       T01058                                  Gene name ADCY5 Definition (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism ecb  Equus caballus (horse) Pathway ecb00230   Purine metabolism ecb01100   Metabolic pathways ecb01522   Endocrine resistance ecb04015   Rap1 signaling pathway ecb04022   cGMP-PKG signaling pathway ecb04024   cAMP signaling pathway ecb04062   Chemokine signaling pathway ecb04072   Phospholipase D signaling pathway ecb04114   Oocyte meiosis ecb04211   Longevity regulating pathway ecb04213   Longevity regulating pathway - multiple species ecb04261   Adrenergic signaling in cardiomyocytes ecb04270   Vascular smooth muscle contraction ecb04371   Apelin signaling pathway ecb04540   Gap junction ecb04611   Platelet activation ecb04713   Circadian entrainment ecb04714   Thermogenesis ecb04723   Retrograde endocannabinoid signaling ecb04724   Glutamatergic synapse ecb04725   Cholinergic synapse ecb04726   Serotonergic synapse ecb04727   GABAergic synapse ecb04728   Dopaminergic synapse ecb04750   Inflammatory mediator regulation of TRP channels ecb04911   Insulin secretion ecb04912   GnRH signaling pathway ecb04913   Ovarian steroidogenesis ecb04914   Progesterone-mediated oocyte maturation ecb04915   Estrogen signaling pathway ecb04916   Melanogenesis ecb04918   Thyroid hormone synthesis ecb04921   Oxytocin signaling pathway ecb04923   Regulation of lipolysis in adipocytes ecb04924   Renin secretion ecb04925   Aldosterone synthesis and secretion ecb04926   Relaxin signaling pathway ecb04927   Cortisol synthesis and secretion ecb04928   Parathyroid hormone synthesis, secretion and action ecb04934   Cushing syndrome ecb04935   Growth hormone synthesis, secretion and action ecb04970   Salivary secretion ecb04971   Gastric acid secretion ecb04972   Pancreatic secretion ecb04976   Bile secretion ecb05012   Parkinson disease ecb05030   Cocaine addiction ecb05031   Amphetamine addiction ecb05032   Morphine addiction ecb05034   Alcoholism ecb05163   Human cytomegalovirus infection ecb05166   Human T-cell leukemia virus 1 infection ecb05200   Pathways in cancer ecb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ecb00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100070498 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100070498 (ADCY5)    04371 Apelin signaling pathway     100070498 (ADCY5)    04072 Phospholipase D signaling pathway     100070498 (ADCY5)    04024 cAMP signaling pathway     100070498 (ADCY5)    04022 cGMP-PKG signaling pathway     100070498 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100070498 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     100070498 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100070498 (ADCY5)    04062 Chemokine signaling pathway     100070498 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     100070498 (ADCY5)    04923 Regulation of lipolysis in adipocytes     100070498 (ADCY5)    04912 GnRH signaling pathway     100070498 (ADCY5)    04913 Ovarian steroidogenesis     100070498 (ADCY5)    04915 Estrogen signaling pathway     100070498 (ADCY5)    04914 Progesterone-mediated oocyte maturation     100070498 (ADCY5)    04921 Oxytocin signaling pathway     100070498 (ADCY5)    04926 Relaxin signaling pathway     100070498 (ADCY5)    04935 Growth hormone synthesis, secretion and action     100070498 (ADCY5)    04918 Thyroid hormone synthesis     100070498 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     100070498 (ADCY5)    04916 Melanogenesis     100070498 (ADCY5)    04924 Renin secretion     100070498 (ADCY5)    04925 Aldosterone synthesis and secretion     100070498 (ADCY5)    04927 Cortisol synthesis and secretion     100070498 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100070498 (ADCY5)    04270 Vascular smooth muscle contraction     100070498 (ADCY5)   09154 Digestive system    04970 Salivary secretion     100070498 (ADCY5)    04971 Gastric acid secretion     100070498 (ADCY5)    04972 Pancreatic secretion     100070498 (ADCY5)    04976 Bile secretion     100070498 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     100070498 (ADCY5)    04727 GABAergic synapse     100070498 (ADCY5)    04725 Cholinergic synapse     100070498 (ADCY5)    04728 Dopaminergic synapse     100070498 (ADCY5)    04726 Serotonergic synapse     100070498 (ADCY5)    04723 Retrograde endocannabinoid signaling     100070498 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100070498 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     100070498 (ADCY5)    04213 Longevity regulating pathway - multiple species     100070498 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     100070498 (ADCY5)    04714 Thermogenesis     100070498 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100070498 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     100070498 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     100070498 (ADCY5)    05031 Amphetamine addiction     100070498 (ADCY5)    05032 Morphine addiction     100070498 (ADCY5)    05034 Alcoholism     100070498 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100070498 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100070498 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100070498 (ADCY5)    05163 Human cytomegalovirus infection     100070498 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100070498 (ADCY5) Enzymes [BR:ecb01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100070498 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD Motif Other DBs NCBI-GeneID:  100070498 NCBI-ProteinID:  XP_001917101 Ensembl:  ENSECAG00000009948 VGNC:  15090 LinkDB All DBs Position 19 AA seq 1259 aa AA seqDB search MSSSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADSRANGYPHAPGGSARSSTKKPGGA VTPQQQQRLASRWRSDDDDDPPLSGDDPLVGGFGFSFRSKSAWQERGGDDCGRGSRRQRR GAAGGGSTRAPPAGGGGGSAAAAAAAGGREVRPRSVELGLEERRGKGRAADELEAGAVEG DEGSGDGGSSAGSDAGPGPVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSSL TMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAAFHQDHMGLAC YALIAVVLAVQVVGLLMPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHL AIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQ RENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLA SQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGM DMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG RIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQ RTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFLGR AIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQVTI VPHSVFMLSFYLTCFLLLTLAVFVSVIYSCVKLFPVPLQTLSRKIVRSKMNSTLLGVFSI ILVFLSAFVNMFMCNSRDLFSCLAEEHNISASQVNACHVVESAVNYSLGDEQGFCGSPWP NCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIVEVPGVTLFDNADLLV TANAIEFNNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQA TEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSE FYVELEANNEGVECLRLLNEIIADFDEIISEDRFKQLEKIKTIGSTYMAASGLNDSTYDK VGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNT VNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS NT seq 3780 nt NT seq  +upstreamnt  +downstreamnt atgtccagctccaaaagcgtgagccccccgggctacgcggcgcagacagcggcggcgccg gcgtcccggggaggcccggaacaccgctccgcgtggggggaggccgattcccgcgccaat ggctacccccacgcccccgggggttcggcccgcagctccaccaagaaacccgggggggcg gtgaccccgcaacagcagcagcgcctggccagccgctggcgcagcgacgacgatgacgat cctccgctgagtggcgacgaccccctggtcgggggcttcggcttcagcttccgctccaag tcagcctggcaggagcgcggcggcgacgactgcggtcgcggcagccgccggcagcggcgg ggcgcggccggcgggggcagcacccgggcgccccctgcgggcggcggcggcggctcggcg gccgcggcggccgcagcgggcgggagggaggtgcgcccccgctcggtggagctgggcctg gaggagcggcggggcaagggccgcgcggccgacgagctggaggccggcgccgtcgagggc gatgagggctccggggatggcggcagctcggcgggctcggacgcgggtcccggcccggtg ctgtcgctgggcgcctgctgcctggcgctgctgcagatattccgctccaagaagttcccg tcggacaagctggagcggctgtaccagcgctactttttccgtctgaaccagagcagcctc accatgctcatggccgtgctggtgctcgtgtgcctcgtcatgttggccttccacgcggcg cggcccccgctccagctgccctacctggccgtgctggcggccgccgtgggcgtgatcctg gtcatggcggtgctctgcaaccgcgccgccttccaccaggaccacatgggcctggcctgc tacgcgctcatcgccgtggtgctggccgtccaggtggtgggcctgctgatgccccagccg cgcagcgcctccgagggcatctggtggaccgtgttcttcatctacaccatctacacgctg ctgcctgtgcgcatgcgggccgcggtactaagcggggtgctcctgtctgccctgcatctg gccattgccctgcgcaccaacgcccaggaccagttcctgctcaagcagcttgtctccaat gtcctcattttctcctgcaccaacatcgtgggtgtctgcacccactacccggccgaggtc tcccagagacaggccttccaggagacccgggagtgcatccaggcgcggctccactcacag cgggagaaccagcagcaggagcggcttctgctgtctgtccttccccgtcatgttgccatg gagatgaaagcagacatcaatgccaaacaggaggatatgatgttccacaagatttacatc cagaaacatgacaacgtgagcatcctgtttgctgacatcgagggcttcaccagcctggcg tcccagtgcactgcccaggagctggtcatgaccctcaacgagctcttcgcccgcttcgac aagctggccgcggagaaccactgtttacgtattaagatcctgggggattgttattactgt gtttcggggctgcctgaagcgagggctgaccatgcccactgctgcgtggagatgggcatg gacatgattgaggccatctcgttggtccgggaggtgacaggggtgaacgtgaacatgcgc gtgggaatccacagcgggcgagtacactgcggtgtccttggtctcaggaagtggcagttc gacgtctggtctaacgacgtcacgctagccaaccacatggaggctggaggcaaggcggga cgcatccacatcaccaaggccacactcaactacctgaacggtgactacgaggtggagcca ggctgtgggggcgagcgcaacgcctacctcaaggagcacagcatcgagaccttcctcatc ctgcgctgcacccagaagcggaaagaagagaaggccatgatcgccaagatgaatcgccag agaaccaattccatcgggcacaacccgccacactggggggccgaacgccccttctacaac cacctgggtggcaaccaggtgtccaaggagatgaagcggatgggctttgaagaccccaag gacaagaacgcccaggaaagtgcaaaccctgaggatgaagtggacgaatttctgggccgt gccattgacgccaggagcatcgacaggctgcgatctgagcatgtccgcaagttcctcttg actttcagggaacctgacttagagaagaagtactccaagcaggtggatgaccgattcggt gcctacgtggcgtgtgcctcgctggtcttcctcttcatctgctttgtccaggtcaccatc gtgccccactccgtgttcatgttgagtttctacctgacgtgtttcctgctgctgaccttg gcggtgtttgtgtccgtgatctactcctgcgtgaagctcttcccggtgcccctgcagacc ctgtccaggaaaatcgtgcggtccaagatgaacagcaccctgctcggggtgttcagcatc atcctggtgttcctgtcggcttttgtcaacatgttcatgtgcaactccagggacctgttc agctgcctggcggaggagcacaacatcagtgccagccaggtcaacgcgtgccacgtggtg gagtccgccgtcaactacagcctgggcgatgaacagggcttctgcggcagcccctggccc aactgcaacttccccgagtacttcacctacagcgtgctgctcagcctgctggcctgctcc gtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatcgagctcatc tacgtgctcatcgtcgaggtgcccggtgtcacactctttgacaatgccgacctgctggtc accgccaacgccatcgagttcaacaacaacgggacctcccagtgccctgagcatgccacc aaggtggcgctgaaggtggtgacgcccatcatcatctcagtcttcgtgctggccctgtac ctgcacgcccagcaggtggagtccaccgcccgccttgacttcctctggaaactgcaggcc acagaggagaaggaggagatggaagagctgcaggcctacaaccgccggctgctgcacaac atcctgcccaaggacgtggccgcccacttcctggcccgcgagcggcgcaacgatgagctg tactatcagtcgtgcgagtgcgtggccgtcatgttcgcctccatcgccaacttctccgag ttctacgtggagctggaggccaacaacgagggcgtcgagtgcctgcggctgctcaacgag atcatcgccgactttgatgagatcatcagcgaggatcggttcaagcagctggaaaagatc aagaccatcggcagcacctacatggccgcctcgggcctcaacgactccacctacgacaaa gtgggcaagacccacatcaaggctctggccgacttcgccatgaagctgatggaccagatg aagtacatcaacgagcactccttcaacaacttccagatgaagatcgggctcaatatcggc cccgtggtggctggggtgatcggggcccgcaagcctcagtatgacatctggggcaatacg gtgaatgtggccagccgcatggacagcaccggtgtgcccgaccgcatccaggtcaccaca gacatgtaccaggtgctggccgccaacacttaccagctggagtgccggggtgtggtcaag gtcaagggcaaaggcgagatgatgacctacttcctcaatggagggcccccgctcagttag

Equus caballus (horse): 100071337 Help Entry 100071337         CDS       T01058                                  Gene name ADCY2 Definition (RefSeq) adenylate cyclase type 2 isoform X1   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism ecb  Equus caballus (horse) Pathway ecb00230   Purine metabolism ecb01100   Metabolic pathways ecb01522   Endocrine resistance ecb04015   Rap1 signaling pathway ecb04020   Calcium signaling pathway ecb04022   cGMP-PKG signaling pathway ecb04024   cAMP signaling pathway ecb04062   Chemokine signaling pathway ecb04072   Phospholipase D signaling pathway ecb04114   Oocyte meiosis ecb04211   Longevity regulating pathway ecb04213   Longevity regulating pathway - multiple species ecb04261   Adrenergic signaling in cardiomyocytes ecb04270   Vascular smooth muscle contraction ecb04371   Apelin signaling pathway ecb04540   Gap junction ecb04611   Platelet activation ecb04713   Circadian entrainment ecb04714   Thermogenesis ecb04723   Retrograde endocannabinoid signaling ecb04724   Glutamatergic synapse ecb04725   Cholinergic synapse ecb04727   GABAergic synapse ecb04750   Inflammatory mediator regulation of TRP channels ecb04911   Insulin secretion ecb04912   GnRH signaling pathway ecb04913   Ovarian steroidogenesis ecb04914   Progesterone-mediated oocyte maturation ecb04915   Estrogen signaling pathway ecb04916   Melanogenesis ecb04918   Thyroid hormone synthesis ecb04921   Oxytocin signaling pathway ecb04922   Glucagon signaling pathway ecb04923   Regulation of lipolysis in adipocytes ecb04925   Aldosterone synthesis and secretion ecb04926   Relaxin signaling pathway ecb04927   Cortisol synthesis and secretion ecb04928   Parathyroid hormone synthesis, secretion and action ecb04934   Cushing syndrome ecb04935   Growth hormone synthesis, secretion and action ecb04970   Salivary secretion ecb04971   Gastric acid secretion ecb04972   Pancreatic secretion ecb04976   Bile secretion ecb05032   Morphine addiction ecb05163   Human cytomegalovirus infection ecb05166   Human T-cell leukemia virus 1 infection ecb05200   Pathways in cancer ecb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ecb00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100071337 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100071337 (ADCY2)    04371 Apelin signaling pathway     100071337 (ADCY2)    04020 Calcium signaling pathway     100071337 (ADCY2)    04072 Phospholipase D signaling pathway     100071337 (ADCY2)    04024 cAMP signaling pathway     100071337 (ADCY2)    04022 cGMP-PKG signaling pathway     100071337 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100071337 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     100071337 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100071337 (ADCY2)    04062 Chemokine signaling pathway     100071337 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     100071337 (ADCY2)    04922 Glucagon signaling pathway     100071337 (ADCY2)    04923 Regulation of lipolysis in adipocytes     100071337 (ADCY2)    04912 GnRH signaling pathway     100071337 (ADCY2)    04913 Ovarian steroidogenesis     100071337 (ADCY2)    04915 Estrogen signaling pathway     100071337 (ADCY2)    04914 Progesterone-mediated oocyte maturation     100071337 (ADCY2)    04921 Oxytocin signaling pathway     100071337 (ADCY2)    04926 Relaxin signaling pathway     100071337 (ADCY2)    04935 Growth hormone synthesis, secretion and action     100071337 (ADCY2)    04918 Thyroid hormone synthesis     100071337 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     100071337 (ADCY2)    04916 Melanogenesis     100071337 (ADCY2)    04925 Aldosterone synthesis and secretion     100071337 (ADCY2)    04927 Cortisol synthesis and secretion     100071337 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100071337 (ADCY2)    04270 Vascular smooth muscle contraction     100071337 (ADCY2)   09154 Digestive system    04970 Salivary secretion     100071337 (ADCY2)    04971 Gastric acid secretion     100071337 (ADCY2)    04972 Pancreatic secretion     100071337 (ADCY2)    04976 Bile secretion     100071337 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     100071337 (ADCY2)    04727 GABAergic synapse     100071337 (ADCY2)    04725 Cholinergic synapse     100071337 (ADCY2)    04723 Retrograde endocannabinoid signaling     100071337 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100071337 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     100071337 (ADCY2)    04213 Longevity regulating pathway - multiple species     100071337 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     100071337 (ADCY2)    04714 Thermogenesis     100071337 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100071337 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     100071337 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100071337 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100071337 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100071337 (ADCY2)    05163 Human cytomegalovirus infection     100071337 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100071337 (ADCY2) Enzymes [BR:ecb01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100071337 (ADCY2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N HNOBA Motif Other DBs NCBI-GeneID:  100071337 NCBI-ProteinID:  XP_023481630 Ensembl:  ENSECAG00000016266 VGNC:  15087 LinkDB All DBs Position 21 AA seq 1095 aa AA seqDB search MWQEAMRRRRYLRDRAEAAAAAAAGGGDGLQRSRDWLYESYYCMSQQHPLIVFLLLIVMG ACLALLAVFFALRLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRVFSLVIWMC LVAMGYLFMCFGGTVSAWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVC LSATPGAKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFE KRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADI VGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAK NCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHM EAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQHL FRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQ NRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKILEKEYRATA LPAFKYYVTCACLIFFCIFIVQILVLPKTSVLGISFGAAFLSLAFILFVCFAGQLLQCSK KASASLLWLLKSSGIIANRPWPRICLTVVTTAIILTMAVFNMFFLSDSEETIPATANISN TSLSASSNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMAALVGYNTI LLHTHAHVLDDYSQVLFERPGIWKDLKTMGSVSLFIFFITLLVLGRQNEYYCRLDFLWKN KFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEDLYHQSYDCVCVMFASIPDF KEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPS QEHAQEPERQYMHIGTMVEFAFALVAKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKP QYDIWGNTVNVASRMDSTGVLDKIQVTEETSLILQTLGYTCTCRGIINVKGKGELKTYFV NTEMSRSLSQSNLAS NT seq 3288 nt NT seq  +upstreamnt  +downstreamnt atgtggcaggaggcgatgcggcgccgccgctacctgcgggaccgcgccgaggcggcggcg gcggcagcggcgggcggcggcgacgggctgcagcggtcccgggactggctctatgagtcc tactactgcatgagccagcagcacccgctcatcgtcttcctgctgctcatcgtcatgggc gcctgcctcgccctgctcgccgtcttcttcgcgctccggctggaagttgaagaccacgtg gcgtttttaataacagttcccactgccctggcgatcttctttgcgatattcatcctggtc tgcatcgagtctgtgtttaagaagctgctccgcgtcttctcattggtgatatggatgtgt ctcgtggccatggggtacttgttcatgtgttttggaggtaccgtctctgcctgggatcag gtatcattcttcctcttcatcatcttcgtggtgtacaccatgctgcccttcaacatgaga gatgccatcattgccagtgtgctcacctcctcctcccacaccatcgtgctgagcgtctgc ctgtctgcaacacccggggccaaggagcacctagtctggcagatcctggccaacgtgatc attttcatctgtgggaacctggctggagcataccataagcacctcatggagctcgcgctg cagcaaacatatcaggacacgtgcaattgcataaagtcccggatcaagttagaatttgaa aagcgtcagcaggagcggctcctgctgtccctgctgccggctcacatagccatggagatg aaggccgagatcatccagaggctgcagggccccaaagccggccaaatggaaaacacaaac aactttcacaacctgtacgtcaagcggcacaccaacgtcagtatcctctacgctgacatt gttggcttcacccggctggccagcgactgctcccccggagaactagtgcacatgctgaat gaactcttcggaaagttcgatcaaattgcaaaggagaatgaatgcatgagaataaaaatt ttaggagactgctactactgtgtgtctggactccctatatctctccctaaccacgccaaa aactgtgtgaaaatggggctggatatgtgtgaagccataaagaaagtgagggatgccact ggagttgatatcaacatgcgcgtgggagtgcattctgggaacgtcctctgcggtgtgatt ggtctgcagaagtggcagtacgatgtgtggtcacatgatgttaccttggccaaccacatg gaagctggaggggtccctggacgtgttcacatttcttcagtcaccctggagcacttgaat ggggcttataaagtggaggaaggagatggtgacatcagggacccatatttaaaacagcac ctggtgaaaacctactttgtaatcaaccccaagggagaacgacggagtccccagcacctc ttcagacctcgccacaccctcgatggagccaagatgagggcctccgtccgcatgacccgg tacctggaatcctggggggcggccaagccgtttgctcacctgcatcacagagacagcatg accacggagaacggcaagatcagcaccacggatgtaccaatgggtcagcataattttcaa aatcgcacattaagaaccaagtcacaaaagaaaaggtttgaagaggaactaaatgaaagg atgattcaagcaattgatggaattaatgcacaaaagcaatggctcaagtctgaagatatt cagagaatctcattgcttttctacaataaaatactagaaaaagaataccgagccactgca ctgccggcattcaagtactacgtgacttgcgcttgtctcatattcttctgcatctttatt gtgcagattctggtattaccaaaaacgtccgttctcgggatttcctttggagctgcattt ctctcgcttgcctttatccttttcgtctgctttgctggacagcttttgcaatgcagcaaa aaggcctctgcctctctcctatggcttctgaagtcatctggcatcatcgcgaaccgcccc tggccgcggatctgcctcacggtcgtcaccacggccatcatattaaccatggccgtgttc aacatgtttttcctgagtgactcagaggagaccatccctgcaactgccaatatatcaaac acaagtctttctgcctcaagtaatcaggcagcgattctgcgtgcgcaaaatttgtttttc cttccgtactttatctacagctgcattctgggattgatctcctgttcggttttcctgcgg gtgaattatgagttgaaaatgttgatcatgatggccgcattggtgggctacaataccatc ctccttcacactcacgcccacgtcctggatgactacagccaggtcttattcgagagacca ggcatttggaaagacctaaagaccatgggttcagtgtctctctttatattcttcatcaca ctgcttgttctggggagacagaatgaatattactgtaggttagacttcttatggaagaac aagttcaaaaaagagcgggaggagatagaaaccatggagaacctgaaccgcgtgctgctg gagaacgtgcttcccgcgcacgtggccgagcatttcctggcccggagtctgaagaatgag gacttataccaccagtcctatgactgtgtctgcgtcatgtttgcctccatcccggatttc aaagaattctatacggaatcagatgtgaacaaggagggcctggaatgccttcggctcctg aacgagatcatcgctgactttgatgatctgctgtccaagccaaagttcagtggagttgaa aagatcaagaccatcggcagcacatacatggctgcgacggggctgagcgccgtgcccagc caggagcacgcccaggagcccgagaggcagtacatgcacataggcaccatggtggagttc gcctttgcgctggtggccaaactggacgccatcaacaagcactccttcaacgacttcaag ttgcgagtgggtattaatcatggacctgtaatagctggtgtaattggagctcagaagcca caatatgatatctggggcaacactgtaaatgtggccagtaggatggatagcaccggagtt ctggacaaaatacaggttactgaggagacgagcctcattctgcagaccctgggatacacg tgcacatgtcgaggaataatcaacgtgaaaggaaagggggaactgaagacatactttgta aacacagaaatgtcgaggtccctctcccagagcaacctggcttcctga

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