Equus caballus (horse): 100056013
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Entry
100056013 CDS
T01058
Gene name
MET
Definition
(RefSeq) hepatocyte growth factor receptor precursor
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb01521
EGFR tyrosine kinase inhibitor resistance
ecb04010
MAPK signaling pathway
ecb04014
Ras signaling pathway
ecb04015
Rap1 signaling pathway
ecb04020
Calcium signaling pathway
ecb04151
PI3K-Akt signaling pathway
ecb04360
Axon guidance
ecb04510
Focal adhesion
ecb04520
Adherens junction
ecb05100
Bacterial invasion of epithelial cells
ecb05144
Malaria
ecb05200
Pathways in cancer
ecb05202
Transcriptional misregulation in cancer
ecb05205
Proteoglycans in cancer
ecb05206
MicroRNAs in cancer
ecb05211
Renal cell carcinoma
ecb05218
Melanoma
ecb05223
Non-small cell lung cancer
ecb05225
Hepatocellular carcinoma
ecb05226
Gastric cancer
ecb05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100056013 (MET)
04014 Ras signaling pathway
100056013 (MET)
04015 Rap1 signaling pathway
100056013 (MET)
04020 Calcium signaling pathway
100056013 (MET)
04151 PI3K-Akt signaling pathway
100056013 (MET)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100056013 (MET)
04520 Adherens junction
100056013 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
100056013 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100056013 (MET)
05202 Transcriptional misregulation in cancer
100056013 (MET)
05206 MicroRNAs in cancer
100056013 (MET)
05205 Proteoglycans in cancer
100056013 (MET)
05230 Central carbon metabolism in cancer
100056013 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100056013 (MET)
05226 Gastric cancer
100056013 (MET)
05218 Melanoma
100056013 (MET)
05211 Renal cell carcinoma
100056013 (MET)
05223 Non-small cell lung cancer
100056013 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
100056013 (MET)
09174 Infectious disease: parasitic
05144 Malaria
100056013 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100056013 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100056013 (MET)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100056013 (MET)
Protein kinases [BR:
ecb01001
]
Receptor tyrosine kinases (RTK)
MET family
100056013 (MET)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Sema
TIG
Pkinase
PSI
Pkinase_fungal
Kinase-like
Ninjurin
Motif
Other DBs
NCBI-GeneID:
100056013
NCBI-ProteinID:
NP_001107619
Ensembl:
ENSECAG00000010385
VGNC:
20111
UniProt:
Q2QLA9
LinkDB
All DBs
Position
4
AA seq
1381 aa
AA seq
DB search
MKAPAVLAPGILVLLFTLVQKSDGECKEALVKSEMNVNMKYQLPNFTAETPIQNVVLHKH
HIYLGATNYIYVLNDKDLQKVAEYKTGPVLEHPDCFPCQDCSRKANLSGGAWKDNINMAL
LVDTYYDDQLISCGSVHRGTCQRHVLPLNNVADIQSEVYCMYSPQAEEPHQCPDCVVSAL
GTKVLLSEKDRFVTFFVGNTINSSYLPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLPE
FRDSYPIKYIHAFESNHFIYFLTVQRETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECIL
TEKRRKRSTSEEVFNILQAAYVSKPGAHLAKQIGANLNDDILYGVFAQSKPDSAEPMNRS
AVCAFPVKYVNEFFNKIVNKNNVRCLQHFYGPHHEHCFNRTLLRNSSGCEVRNDEYRTEF
TTALQRVDLFMGQFNQVLLTSISTFIKGNLTIANLGTSEGRFMQVVVSRSGSSTPHVNFH
LDSHPVSPEVIVEHPLNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPPFVQCGW
CHDKCVRLEECHNGTWTQEICLPTIYKVFPTSAPLEGGTTLTVCGWDFGFRKNNKLDSKK
TKVLLGNESCTLTLSESTSNTLKCTVGPAMNERFNISITVSNSRGTARYSTFSYVDPIIT
SISPSYGPKTGGTLLTLTGKYLNSGNSRHISIGGKTCTLKSVSDSILECYTPAQTTPTEF
PVKLKIDLANREMNSFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVLRMVINVR
EAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNPV
FKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHSHSEAVLCTVPSDL
LKLNSELNIEWKQAVSSTILGKVIVQPDQNFTGLIVGVVSISIILLLLLGLFLWLKRRKQ
IKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGS
CRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHF
NEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL
SLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKF
VHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF
TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCW
HPKAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNVDGEVD
T
NT seq
4146 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcacctgctgtgcttgcacctggcatccttgtgcttctgtttaccttggtgcag
aagagcgatggggagtgtaaagaggcgctagtaaagtccgagatgaatgtgaacatgaag
tatcagcttcccaacttcactgcagaaacacccatccagaacgtcgttttacacaagcat
cacatttacctcggggccactaactacatttatgttttaaatgacaaagatcttcagaaa
gttgctgagtacaagactgggcccgtgctggaacacccagattgtttcccatgtcaggac
tgcagccgcaaagccaatttatcaggtggcgcttggaaagataacatcaacatggctctg
cttgttgacacatactatgacgatcaactcattagttgcggcagcgtccacagagggacc
tgccagcggcacgtccttccactcaacaatgttgctgacatacagtcagaagtttattgc
atgtactctccacaagcagaagagccccaccagtgtcctgactgtgtggtgagtgccctg
ggaaccaaagtcctgctgtctgaaaaggaccgatttgtcaccttcttcgtgggcaatacc
ataaattcttcttaccttccagatcattcattgcattcgatatcggtgagaaggctaaag
gaaacgcaagatggttttaagtttttgacagatcagtcctatattgatgttctacctgag
ttccgagattcttaccccattaagtatatccacgcctttgaaagcaaccattttatttac
tttttaacggtccaacgggaaactctagatgctcagacttttcacacaagaataatcagg
ttctgttccgtggactctggattgcattcctacatggaaatgcctctggagtgtattctc
acagaaaagagaagaaagagatccacaagtgaggaagtgtttaatatcctccaagctgcg
tatgtcagtaagcctggggctcatcttgctaagcaaataggtgccaacctgaatgatgac
attctctatggggtgtttgcacagagcaagccagattctgctgaaccaatgaatcgctct
gccgtctgtgcattccctgtcaaatatgtcaatgaattcttcaacaagattgtcaacaaa
aacaacgtgagatgtctccagcatttttatggaccccaccatgaacactgcttcaatagg
acacttttgagaaattcatcaggctgtgaagtgcgcaatgatgaatatcgaacggagttt
accacagctttgcagcgcgttgacttgttcatgggccaattcaaccaagtcctcttgaca
tctatatccaccttcattaaaggaaacctcactatagctaatcttgggacatcagaaggt
cgcttcatgcaggttgtggtttctcgatcaggatcgtcaacccctcatgtgaattttcac
ctggattcccaccctgtgtctccagaagtgattgtggaacacccattaaaccaaaatggt
tacacactggttgtcaccgggaaaaagatcaccaagatcccactgaatggcttgggctgt
gaacatttccagtcctgcagtcagtgtctctccgcccctccctttgtgcagtgtggctgg
tgccacgacaaatgtgtgcgattggaggaatgccacaacggaacatggactcaagagatc
tgtctgcctacaatctacaaggttttcccaaccagtgcccccctcgaaggagggacaacg
ctgacagtatgtggctgggactttggattcaggaagaataataaacttgattcaaagaaa
accaaagttctccttggaaatgagagctgcaccttgactttaagtgagagcacgtcaaat
acgttgaaatgcacagttggtcctgcaatgaatgagcgtttcaatatatccataactgtt
tccaacagtcgagggacagcacgatatagtacattttcctatgtggatcctataataaca
agtatttctccaagttatggtcctaagactggtggcactttacttactttaactggaaag
tacttaaacagtgggaattctagacacatttcaattggtggaaaaacatgtaccttaaaa
agtgtgtcagatagtattcttgaatgttatactccagcccaaaccactccaactgagttt
cccgttaaactgaaaattgacttagccaaccgagagatgaacagcttcagttaccgggaa
gaccccattgtctatgaaattcatccaaccaaatcttttattagtggtgggagcacaatt
acaggtgttggaaaaaatctgaattcggttagtgtcctgaggatggtgataaatgtgcgt
gaagcaggaaggaactttacagtggcatgtcagcatcgctctaattcagagataatctgc
tgtacaactccttcactacaacagctgaatttgcaactccctctgaaaaccaaagccttc
ttcatgttggacgggatccattccaaatactttgatctcatttatgtacataatcctgtg
tttaagccttttgaaaagccagtgatgatctcaataggcaatgaaaatgtactggaaatt
aagggaaatgatattgaccctgaagccgttaaaggtgaagtgttaaaagttggaaataag
agctgtgagaatatacactcacattctgaagccgttttatgtacagtccccagtgacctg
ctgaaattgaacagcgagctaaatatagagtggaagcaagcagtttcttcaaccatcctt
ggaaaagtaatagttcaaccagatcagaatttcacaggattgattgttggtgttgtctca
atatcaataatactcttattattactcgggcttttcctgtggctgaaaaggagaaagcaa
attaaagatctgggcagtgaattagttcgctatgatgcaagagtacacactcctcatttg
gataggcttgtaagtgcccgaagtgtaagcccaactacagaaatggtttcaaatgaatct
gtagactaccgagctacttttccagaagaccagtttcctaactcatctcagaatggatca
tgcagacaagtgcagtatcctctgacggacctatcccccatcctaactagtggggactct
gatatatccagtccattactgcaaaataccgtccacattgacctcagtgctctaaatcca
gagctggtgcaggcagtccagcacgtagtgattgggcctagtagtctgattgtgcatttc
aatgaagtcataggaagaggacattttgggtgtgtatatcatgggactttgttggacaat
gatgacaagaaaattcactgtgctgtgaaatccttgaatagaatcactgacataggagaa
gtttcccagtttctcaccgagggaattatcatgaaagattttagtcatcccaacgttctc
tcgctcttgggaatctgccttcgaagtgagggatctccactggtggttctaccgtacatg
aaacatggagaccttcgaaatttcattagaaatgagacccacaacccaactgtaaaagat
cttattggctttggtcttcaagtagccaaaggcatgaaatatcttgcaagcaaaaagttt
gtccacagagacttggctgcaagaaactgtatgctggatgaaaaattcactgtcaaggtt
gctgattttgggcttgccagagacatgtatgataaagaatactatagtgtgcacaacaaa
acaggtgcaaaactgcctgtgaagtggatggctttagagagtctgcaaactcagaagttt
accaccaagtcagatgtgtggtcctttggcgtgctcctctgggagctgatgacaagagga
gcaccaccttatcccgatgtcaacacctttgatataacagtttacttgttgcaaggcaga
aggctcttacaaccagagtactgcccagatcccttgtatgaagtgatgctaaaatgctgg
caccctaaagctgaactgcgcccatccttttctgaactggtctccaggatatcagcgata
ttctctactttcatcggggagcactacgtccatgtgaacgctacttatgtgaatgtgaaa
tgtgttgctccatatccttctctgttgtcatcacaagataacgttgatggcgaggtagat
acatga
DBGET
integrated database retrieval system
