KEGG   Equus caballus (horse): 100062208Help
Entry
100062208         CDS       T01058                                 

Gene name
HDAC6
Definition
(RefSeq) histone deacetylase 6 isoform X1
  KO
K11407  histone deacetylase 6 [EC:3.5.1.98]
Organism
ecb  Equus caballus (horse)
Pathway
ecb05034  Alcoholism
ecb05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09160 Human Diseases
  09161 Cancers: Overview
   05203 Viral carcinogenesis
    100062208 (HDAC6)
  09165 Substance dependence
   05034 Alcoholism
    100062208 (HDAC6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ecb01009]
    100062208 (HDAC6)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:ecb03019]
    100062208 (HDAC6)
   04131 Membrane trafficking [BR:ecb04131]
    100062208 (HDAC6)
   03036 Chromosome and associated proteins [BR:ecb03036]
    100062208 (HDAC6)
Enzymes [BR:ecb01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     100062208 (HDAC6)
Protein phosphatases and associated proteins [BR:ecb01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     100062208 (HDAC6)
Messenger RNA biogenesis [BR:ecb03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     100062208 (HDAC6)
Membrane trafficking [BR:ecb04131]
 Autophagy
  Aggrephagy
   Other aggrephagy associated proteins
    100062208 (HDAC6)
Chromosome and associated proteins [BR:ecb03036]
 Eukaryotic Type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class II HDACs
     100062208 (HDAC6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Hist_deacetyl zf-UBP zf-UBP_var
Motif
Other DBs
NCBI-GeneID: 100062208
NCBI-ProteinID: XP_005614176
Ensembl: ENSECAG00000000227
VGNC: 50595
LinkDB All DBs
Position
X
AA seq 1229 aa AA seqDB search
MEKKTSGTRGATGRREFGGGSQGRSLRKGLRSNVVRGEASPTMTSTGQDSTTTRQRRSRH
NPHSPPHDSSVASKRSVKKGATLRSSPNLAEVKKKGRMKKLSQAADQDLIMGLQGLDLNL
EAKTLSGTGLVFDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEK
EELMLVHSLEYIDLMETTQYMNERELRILADTYDSVYLHPNSYTCACLASGSVLRLVDAV
LGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHEIQRILIVDWDVHHGQ
GTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASDWSTIGFGQGRGYTINVPWNQVGMRDAD
YIAAFLHILLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAHLTHLLMGLAGGKL
ILSLEGGYNLRSLAEGVSASLHTLLGDPCPMLESPGAPCLSAKASLSCTLEALEPFWEVL
VRSVETMEEDIVEGDNVEEKEEGPWQPPALPILTWPVLQARTGLVYDQRMMGHYNLWDSH
HPEMPQRVSRIMRRLEELHLAERCLTLPARPATDAELLTCHSAEYVGRLRATEKMKTREL
HREGANFDSIYICPSTFACAQLATGAVCRLVEAVLAGEVLNGIAVVRPPGHHAEQDAACG
FCFFNSVAVAARHAQAISGHALRILIVDWDVHHGNGTQHIFEEDPSVLYISLHRYDHGTF
FPLGDEGASSQMGQAAGTGFTVNVTWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSA
GFDAARGDPLGGCQVSPEGYAHLTHLLMGLANGHIILILEGGYNLTSISESMAACTRSLL
GDPPPLLTLTRPPLAGALASITETIQVHRRYWRSLQITKVEDKEGPSSSLLITKKAPQPA
NPGSAKEMITPEGNILDAGRGKATSVSSVEESTAGQTKSETAVVELTQDKSLEAATEEAT
LDQTTSETATGEATLDQTTSEIATGEAKLDQATSETAMGGATLDQTTLGATPGVTTLDQT
TSEAVRGAELIQVPPASSTDNQTPPASPVEGDPPHISPSKLIGNLRTLELDNEAQEAPES
QSPEEERLLGEATGGQDMDDLVLMQSFGDNADTDQAMFYAVTPLPWCPHLVAVSPVPDTG
LDVTQPCQDCGALQENWVCLSCHQVYCGRYINAHMLQHHEGSGHPLVLSYVDLSTWCYYC
QAYVHHQALLDAKNVAHQNKFGEGMPHSH
NT seq 3690 nt NT seq  +upstreamnt  +downstreamnt
atggaaaagaagacctcgggcacccgcggcgccacaggtcgccgggaatttggcggcggg
agccaagggcggagtttgagaaaggggctgcgctcaaacgtcgtcaggggtgaagcctcc
ccgaccatgacctctaccggccaggattccaccacaaccaggcagcgaaggagtaggcac
aacccccactcccccccccacgactccagcgtcgcctcgaagaggagtgttaagaagggt
gccacactccgctccagccctaatctagcggaggtaaagaagaaaggcagaatgaagaag
ctcagccaagcagccgaccaagacctaatcatggggctgcaagggctggatctgaacctt
gaggccaagacgctgtctggcactggcttggtgtttgatgagcagctaaatgaatttcat
tgcctctgggatgacagcttccctgaaggccctgagcggctccatgccatcaaggagcag
ctgatccaggagggcctcttggaccgctgtgtgtcctttcaggcccggttcgccgaaaag
gaggagctgatgttggttcacagcctagaatatattgatctgatggagacgacccaatac
atgaatgaaagggaactccgcatcctagcagacacctatgactcagtttatctgcatccg
aactcatacacctgtgcctgcctggcctcaggctctgtcctcaggctggtggatgctgtc
ctgggggccgagatccggaatggcatggccatcatcaggcctcctggacaccatgcccag
cacagtcttatggatgggtattgcatgttcaaccatgtggccgtggctgcccgctacgct
caacagaagcatgaaattcagaggatccttatcgtggattgggatgtacaccatggtcaa
ggaacacagttcacctttgaccaggaccccagcgtcctctatttctccatccaccgctat
gagcagggtcggttctggccccaccttaaggcctctgactggtccaccataggttttggc
caaggccggggatacaccatcaatgtgccttggaaccaggtgggcatgcgagatgccgac
tacattgctgctttcctgcacatcctgctgccagtcgccctggagttccagccacagcta
gtcctggtggctgctggatttgatgccctccaaggggaccccaagggtgagatggctgcc
actccagcagggttcgcccacctgacccacctgctcatgggtctggcaggaggcaagctg
atcctgtctctggagggtggctacaacctccgctctctggctgagggtgtcagcgcctcg
ctccacacccttctgggagatccttgccccatgctggaatcccctggtgccccctgcctg
agtgccaaggcatcactctcctgcactctggaagccctggagcccttctgggaggtcctt
gtgagatcagttgagaccatggaggaggacattgtggagggggacaacgtggaggagaaa
gaggagggaccatggcagccccctgcactcccaatcctgacgtggcctgtgctgcaggct
cgcaccgggctggtctatgaccagcggatgatgggtcactacaacttgtgggacagccat
caccccgagatgcctcagcgtgtctcacggatcatgcgccgtctggaggagctgcacctt
gccgagcgctgccttaccctgcccgcacgtcccgccacagatgctgagcttcttacctgc
cacagtgctgaatatgtgggtcgtctacgggccacggagaagatgaaaacccgggagctg
caccgtgagggcgccaactttgactccatctacatctgccccagcaccttcgcctgcgcg
cagctggccactggcgctgtgtgccgcctggtggaggctgtgctggcgggagaggttttg
aatggtattgctgtggtgcgtcccccgggacaccacgcagagcaggatgccgcttgtggt
ttctgctttttcaactctgtagctgtggctgctcgccatgcccaggccatcagtgggcat
gcgctgcggatcctgatcgtagactgggacgtccatcacggtaatggaactcagcacata
tttgaggaggaccccagcgtgctgtacatttccctgcaccgctatgatcacggtaccttc
ttccccctgggggatgagggcgccagcagccagatgggccaggctgcaggcacaggcttc
actgtcaatgtgacctggaacgggccccgcatgggtgacgctgactacctggctgcctgg
catcgcctggtgcttcccattgcctatgagtttaacccagaactggtgctagtctcagct
ggctttgacgctgcacggggtgacccactgggtggttgccaggtgtcgcctgagggctat
gcccaccttacccacctgctgatgggccttgccaatggccacattatcctaatcctagag
ggtggctataatctgacatccatctcagagtccatggccgcttgcacccgctccctcctt
ggggacccaccacctctgctgaccctgacacggcccccactagcaggggccctggcctcc
atcactgagaccatccaagtccatcgcagatactggcgcagcttgcagatcacaaaggtc
gaagacaaggagggaccatccagttctttgttgatcaccaagaaggcaccccaaccagcc
aatcctgggtcagccaaggagatgatcacaccagaagggaacattctggatgcaggcagg
gggaaggccacctcagtatcatctgtagaagagtctactgcaggccagactaagtcagag
acagctgtggtggagctcactcaggacaagtccttggaggcagccacagaggaagccacg
ctggaccagaccacctcagagacagccacaggggaagccacgctggaccagaccacctca
gagatagccacgggggaagccaagctagaccaggccacctcagagacagccatgggggga
gccacgctggaccagaccaccttgggggcaaccccaggagtaaccacgctggatcagacc
acctcagaggctgtcaggggagctgagctgatccaagtccctccagcctcaagcactgac
aaccagactcccccagcctcacctgtggaaggagacccaccccacatatcccctagtaag
ctgattgggaatctcaggaccttggaactagacaacgaggctcaggaggcaccagaatct
cagagccctgaagaggagagactactaggagaggcaactggaggtcaagacatggatgat
ttagtgctgatgcagagctttggggacaatgctgacactgaccaggccatgttttatgcc
gtgacaccactgccctggtgtcctcatttggtggcagtaagccccgtacctgacacaggc
ctggacgtgacccaaccttgtcaggactgtggagcactccaggagaactgggtgtgtctg
tcttgccatcaggtctactgtggtcgttacatcaatgcccatatgctccaacaccatgaa
ggctcaggacaccctctggtcctcagctacgtcgacctgtctacctggtgttactactgt
caggcttatgtccaccaccaggctctcctagatgcgaagaacgtcgcccaccagaacaag
tttggggagggcatgccccactcacactaa

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