Equus caballus (horse): 100062549 Help Entry 100062549         CDS       T01058                                  Gene name PRKCG Definition (RefSeq) protein kinase C gamma type   KO K19663   classical protein kinase C gamma type [EC:2.7.11.13] Organism ecb  Equus caballus (horse) Pathway ecb01521   EGFR tyrosine kinase inhibitor resistance ecb04010   MAPK signaling pathway ecb04012   ErbB signaling pathway ecb04014   Ras signaling pathway ecb04015   Rap1 signaling pathway ecb04020   Calcium signaling pathway ecb04066   HIF-1 signaling pathway ecb04070   Phosphatidylinositol signaling system ecb04071   Sphingolipid signaling pathway ecb04150   mTOR signaling pathway ecb04270   Vascular smooth muscle contraction ecb04310   Wnt signaling pathway ecb04370   VEGF signaling pathway ecb04510   Focal adhesion ecb04540   Gap junction ecb04613   Neutrophil extracellular trap formation ecb04650   Natural killer cell mediated cytotoxicity ecb04666   Fc gamma R-mediated phagocytosis ecb04670   Leukocyte transendothelial migration ecb04713   Circadian entrainment ecb04720   Long-term potentiation ecb04723   Retrograde endocannabinoid signaling ecb04724   Glutamatergic synapse ecb04725   Cholinergic synapse ecb04726   Serotonergic synapse ecb04727   GABAergic synapse ecb04728   Dopaminergic synapse ecb04730   Long-term depression ecb04750   Inflammatory mediator regulation of TRP channels ecb04911   Insulin secretion ecb04916   Melanogenesis ecb04918   Thyroid hormone synthesis ecb04919   Thyroid hormone signaling pathway ecb04921   Oxytocin signaling pathway ecb04925   Aldosterone synthesis and secretion ecb04928   Parathyroid hormone synthesis, secretion and action ecb04929   GnRH secretion ecb04935   Growth hormone synthesis, secretion and action ecb04960   Aldosterone-regulated sodium reabsorption ecb04961   Endocrine and other factor-regulated calcium reabsorption ecb04970   Salivary secretion ecb04971   Gastric acid secretion ecb04972   Pancreatic secretion ecb05017   Spinocerebellar ataxia ecb05022   Pathways of neurodegeneration - multiple diseases ecb05031   Amphetamine addiction ecb05032   Morphine addiction ecb05143   African trypanosomiasis ecb05146   Amoebiasis ecb05161   Hepatitis B ecb05163   Human cytomegalovirus infection ecb05170   Human immunodeficiency virus 1 infection ecb05171   Coronavirus disease - COVID-19 ecb05200   Pathways in cancer ecb05205   Proteoglycans in cancer ecb05206   MicroRNAs in cancer ecb05214   Glioma ecb05223   Non-small cell lung cancer ecb05225   Hepatocellular carcinoma ecb05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ecb00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100062549 (PRKCG)    04012 ErbB signaling pathway     100062549 (PRKCG)    04014 Ras signaling pathway     100062549 (PRKCG)    04015 Rap1 signaling pathway     100062549 (PRKCG)    04310 Wnt signaling pathway     100062549 (PRKCG)    04370 VEGF signaling pathway     100062549 (PRKCG)    04066 HIF-1 signaling pathway     100062549 (PRKCG)    04020 Calcium signaling pathway     100062549 (PRKCG)    04070 Phosphatidylinositol signaling system     100062549 (PRKCG)    04071 Sphingolipid signaling pathway     100062549 (PRKCG)    04150 mTOR signaling pathway     100062549 (PRKCG)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100062549 (PRKCG)    04540 Gap junction     100062549 (PRKCG)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     100062549 (PRKCG)    04650 Natural killer cell mediated cytotoxicity     100062549 (PRKCG)    04666 Fc gamma R-mediated phagocytosis     100062549 (PRKCG)    04670 Leukocyte transendothelial migration     100062549 (PRKCG)   09152 Endocrine system    04911 Insulin secretion     100062549 (PRKCG)    04929 GnRH secretion     100062549 (PRKCG)    04921 Oxytocin signaling pathway     100062549 (PRKCG)    04935 Growth hormone synthesis, secretion and action     100062549 (PRKCG)    04918 Thyroid hormone synthesis     100062549 (PRKCG)    04919 Thyroid hormone signaling pathway     100062549 (PRKCG)    04928 Parathyroid hormone synthesis, secretion and action     100062549 (PRKCG)    04916 Melanogenesis     100062549 (PRKCG)    04925 Aldosterone synthesis and secretion     100062549 (PRKCG)   09153 Circulatory system    04270 Vascular smooth muscle contraction     100062549 (PRKCG)   09154 Digestive system    04970 Salivary secretion     100062549 (PRKCG)    04971 Gastric acid secretion     100062549 (PRKCG)    04972 Pancreatic secretion     100062549 (PRKCG)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100062549 (PRKCG)    04961 Endocrine and other factor-regulated calcium reabsorption     100062549 (PRKCG)   09156 Nervous system    04724 Glutamatergic synapse     100062549 (PRKCG)    04727 GABAergic synapse     100062549 (PRKCG)    04725 Cholinergic synapse     100062549 (PRKCG)    04728 Dopaminergic synapse     100062549 (PRKCG)    04726 Serotonergic synapse     100062549 (PRKCG)    04720 Long-term potentiation     100062549 (PRKCG)    04730 Long-term depression     100062549 (PRKCG)    04723 Retrograde endocannabinoid signaling     100062549 (PRKCG)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100062549 (PRKCG)   09159 Environmental adaptation    04713 Circadian entrainment     100062549 (PRKCG)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100062549 (PRKCG)    05206 MicroRNAs in cancer     100062549 (PRKCG)    05205 Proteoglycans in cancer     100062549 (PRKCG)    05231 Choline metabolism in cancer     100062549 (PRKCG)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100062549 (PRKCG)    05214 Glioma     100062549 (PRKCG)    05223 Non-small cell lung cancer     100062549 (PRKCG)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     100062549 (PRKCG)    05022 Pathways of neurodegeneration - multiple diseases     100062549 (PRKCG)   09165 Substance dependence    05031 Amphetamine addiction     100062549 (PRKCG)    05032 Morphine addiction     100062549 (PRKCG)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100062549 (PRKCG)    05161 Hepatitis B     100062549 (PRKCG)    05171 Coronavirus disease - COVID-19     100062549 (PRKCG)    05163 Human cytomegalovirus infection     100062549 (PRKCG)   09174 Infectious disease: parasitic    05146 Amoebiasis     100062549 (PRKCG)    05143 African trypanosomiasis     100062549 (PRKCG)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100062549 (PRKCG)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ecb01001]     100062549 (PRKCG) Enzymes [BR:ecb01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      100062549 (PRKCG) Protein kinases [BR:ecb01001]  Serine/threonine kinases: AGC group   PKC family [OT]    100062549 (PRKCG) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C Kinase-like Motif Other DBs NCBI-GeneID:  100062549 NCBI-ProteinID:  XP_001493745 Ensembl:  ENSECAG00000019249 VGNC:  21845 UniProt:  F7CH66 LinkDB All DBs Position 10 AA seq 697 aa AA seqDB search MSGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTADEIHVTVGEA RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRL SVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQ KFEACNYPLELYERVRMGPSSSPIPSPSPSPTDSKRCFFGASPGRLHISDFSFLMVLGKG SFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQL HSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRD LKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWS FGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPAKRLGS GPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCGRSGENFDKFFTRAAPALTPPDRL VLASIDQADFQGFTYVNPDFVHPDARSPISPTPVPVM NT seq 2094 nt NT seq  +upstreamnt  +downstreamnt atgtcaggcctcggccctggcggaggcgattcggaggggggaccccgacccctgttttgc agaaagggggctctgaggcagaaggtggtccacgaagtcaagagccacaagttcaccgct cgcttcttcaagcagccaaccttctgcagccactgcaccgacttcatctggggcattgga aaacagggcctgcaatgtcaagtctgcagctttgtggttcatcgacgatgccacgaattt gtgaccttcgagtgtccaggcgctgggaagggcccccagacggacgatccccggaacaag cacaagttccgtctgcacagctacagcagccccaccttctgcgaccactgtggctccctg ctttacgggctggtgcaccagggcatgaaatgctcctgctgcgagatgaacgtgcaccgg cgctgtgtgcgcagcgtgccctctctgtgcggcgtggaccacacggagcgccgcgggcgc ctgcagctggaaatccgggctccgactgccgatgagattcacgtcacggttggtgaggcc cgtaacctcatccccatggaccccaatggtctgtctgatccctatgtgaaactgaagctc atcccagaccctcggaacttgacaaaacagaagacccggacggtgaaagccacgctaaac cccgtgtggaacgagacctttgtgttcaacctgaagccgggggatgtggagcgcaggctc agcgtcgaggtgtgggactgggaccggacttcccgcaacgacttcatgggtgccatgtcc ttcggcgtctcggagctgctcaaggcgccggtggacggctggtacaagttactgaaccag gaggagggcgaatattacaatgtgccggtggctgatgctgacaactgcagcctcctccag aagtttgaggcctgtaactaccccctggaactgtatgagcgggtgcggatggggccgtcc tcctctcccatcccctccccatcccctagtcccacggactccaagcgctgtttcttcggg gcaagccctggacgtctgcacatctctgacttcagcttcctcatggttctaggaaaaggc agttttgggaaggtgatgctggctgagcgcaggggctctgatgagctctacgccatcaag atcctgaagaaagacgtgatcgtccaggatgacgacgtggactgcaccctggtggaaaaa cgcgtgctggccctcgggggccgaggcccgggaggccggccccactttctcacccagctc cactccaccttccagaccccggatcgcctgtattttgtgatggagtatgtcaccgggggc gacttgatgtaccacatccagcagttgggcaagtttaaggagccccacgcggcgttctat gcagcggaaattgccatcggcctcttcttccttcacaatcagggcatcatttaccgggac ctgaaactggacaacgtgatgctggatgccgaaggacatatcaaaatcactgactttggc atgtgtaaggagaatgtcttccccgggaccaccacccgcaccttctgcgggaccccagac tacatagcccccgagatcattgcctaccagccctatgggaagtctgtggattggtggtcc tttggggttctgttgtatgagatgttggcgggacagccccccttcgatggggaggatgag gaggagctgtttcaggccatcatggaacaaactgtcacctaccccaagtcgctttcccgg gaagccgtggccatctgcaaggggttcctaaccaagcaccccgccaagcgcctgggctca ggcccagacggggaacccaccatccgtgctcacggctttttccgctggatcgactgggag cggctggaacgattggagatcgcgcctccattcagaccccgcccgtgcggccgcagcggg gagaacttcgacaagttcttcacacgggccgcgccagcgctgacccctccagaccgccta gttctggccagcatcgaccaggcagatttccaaggcttcacctacgttaacccggatttt gtgcacccggatgcgcgcagccccatcagcccgacgccggtgccagtcatgtaa

Equus caballus (horse): 100063318 Help Entry 100063318         CDS       T01058                                  Gene name PRKCA Definition (RefSeq) protein kinase C alpha type isoform X1   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism ecb  Equus caballus (horse) Pathway ecb01521   EGFR tyrosine kinase inhibitor resistance ecb04010   MAPK signaling pathway ecb04012   ErbB signaling pathway ecb04014   Ras signaling pathway ecb04015   Rap1 signaling pathway ecb04020   Calcium signaling pathway ecb04066   HIF-1 signaling pathway ecb04070   Phosphatidylinositol signaling system ecb04071   Sphingolipid signaling pathway ecb04072   Phospholipase D signaling pathway ecb04150   mTOR signaling pathway ecb04151   PI3K-Akt signaling pathway ecb04261   Adrenergic signaling in cardiomyocytes ecb04270   Vascular smooth muscle contraction ecb04310   Wnt signaling pathway ecb04360   Axon guidance ecb04370   VEGF signaling pathway ecb04510   Focal adhesion ecb04540   Gap junction ecb04613   Neutrophil extracellular trap formation ecb04650   Natural killer cell mediated cytotoxicity ecb04664   Fc epsilon RI signaling pathway ecb04666   Fc gamma R-mediated phagocytosis ecb04670   Leukocyte transendothelial migration ecb04713   Circadian entrainment ecb04720   Long-term potentiation ecb04723   Retrograde endocannabinoid signaling ecb04724   Glutamatergic synapse ecb04725   Cholinergic synapse ecb04726   Serotonergic synapse ecb04727   GABAergic synapse ecb04728   Dopaminergic synapse ecb04730   Long-term depression ecb04750   Inflammatory mediator regulation of TRP channels ecb04911   Insulin secretion ecb04912   GnRH signaling pathway ecb04916   Melanogenesis ecb04918   Thyroid hormone synthesis ecb04919   Thyroid hormone signaling pathway ecb04921   Oxytocin signaling pathway ecb04925   Aldosterone synthesis and secretion ecb04926   Relaxin signaling pathway ecb04928   Parathyroid hormone synthesis, secretion and action ecb04929   GnRH secretion ecb04933   AGE-RAGE signaling pathway in diabetic complications ecb04935   Growth hormone synthesis, secretion and action ecb04960   Aldosterone-regulated sodium reabsorption ecb04961   Endocrine and other factor-regulated calcium reabsorption ecb04970   Salivary secretion ecb04971   Gastric acid secretion ecb04972   Pancreatic secretion ecb05017   Spinocerebellar ataxia ecb05022   Pathways of neurodegeneration - multiple diseases ecb05031   Amphetamine addiction ecb05032   Morphine addiction ecb05143   African trypanosomiasis ecb05146   Amoebiasis ecb05161   Hepatitis B ecb05163   Human cytomegalovirus infection ecb05164   Influenza A ecb05170   Human immunodeficiency virus 1 infection ecb05171   Coronavirus disease - COVID-19 ecb05200   Pathways in cancer ecb05205   Proteoglycans in cancer ecb05206   MicroRNAs in cancer ecb05214   Glioma ecb05223   Non-small cell lung cancer ecb05225   Hepatocellular carcinoma ecb05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ecb00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100063318 (PRKCA)    04012 ErbB signaling pathway     100063318 (PRKCA)    04014 Ras signaling pathway     100063318 (PRKCA)    04015 Rap1 signaling pathway     100063318 (PRKCA)    04310 Wnt signaling pathway     100063318 (PRKCA)    04370 VEGF signaling pathway     100063318 (PRKCA)    04066 HIF-1 signaling pathway     100063318 (PRKCA)    04020 Calcium signaling pathway     100063318 (PRKCA)    04070 Phosphatidylinositol signaling system     100063318 (PRKCA)    04072 Phospholipase D signaling pathway     100063318 (PRKCA)    04071 Sphingolipid signaling pathway     100063318 (PRKCA)    04151 PI3K-Akt signaling pathway     100063318 (PRKCA)    04150 mTOR signaling pathway     100063318 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100063318 (PRKCA)    04540 Gap junction     100063318 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     100063318 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     100063318 (PRKCA)    04664 Fc epsilon RI signaling pathway     100063318 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     100063318 (PRKCA)    04670 Leukocyte transendothelial migration     100063318 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     100063318 (PRKCA)    04929 GnRH secretion     100063318 (PRKCA)    04912 GnRH signaling pathway     100063318 (PRKCA)    04921 Oxytocin signaling pathway     100063318 (PRKCA)    04926 Relaxin signaling pathway     100063318 (PRKCA)    04935 Growth hormone synthesis, secretion and action     100063318 (PRKCA)    04918 Thyroid hormone synthesis     100063318 (PRKCA)    04919 Thyroid hormone signaling pathway     100063318 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     100063318 (PRKCA)    04916 Melanogenesis     100063318 (PRKCA)    04925 Aldosterone synthesis and secretion     100063318 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100063318 (PRKCA)    04270 Vascular smooth muscle contraction     100063318 (PRKCA)   09154 Digestive system    04970 Salivary secretion     100063318 (PRKCA)    04971 Gastric acid secretion     100063318 (PRKCA)    04972 Pancreatic secretion     100063318 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100063318 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     100063318 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     100063318 (PRKCA)    04727 GABAergic synapse     100063318 (PRKCA)    04725 Cholinergic synapse     100063318 (PRKCA)    04728 Dopaminergic synapse     100063318 (PRKCA)    04726 Serotonergic synapse     100063318 (PRKCA)    04720 Long-term potentiation     100063318 (PRKCA)    04730 Long-term depression     100063318 (PRKCA)    04723 Retrograde endocannabinoid signaling     100063318 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100063318 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     100063318 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     100063318 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100063318 (PRKCA)    05206 MicroRNAs in cancer     100063318 (PRKCA)    05205 Proteoglycans in cancer     100063318 (PRKCA)    05231 Choline metabolism in cancer     100063318 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100063318 (PRKCA)    05214 Glioma     100063318 (PRKCA)    05223 Non-small cell lung cancer     100063318 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     100063318 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     100063318 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     100063318 (PRKCA)    05032 Morphine addiction     100063318 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100063318 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100063318 (PRKCA)    05161 Hepatitis B     100063318 (PRKCA)    05171 Coronavirus disease - COVID-19     100063318 (PRKCA)    05164 Influenza A     100063318 (PRKCA)    05163 Human cytomegalovirus infection     100063318 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     100063318 (PRKCA)    05143 African trypanosomiasis     100063318 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100063318 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ecb01001]     100063318 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ecb04131]     100063318 (PRKCA) Enzymes [BR:ecb01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      100063318 (PRKCA) Protein kinases [BR:ecb01001]  Serine/threonine kinases: AGC group   PKC family [OT]    100063318 (PRKCA) Membrane trafficking [BR:ecb04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     100063318 (PRKCA) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C2 C1_1 Pkinase_C Motif Other DBs NCBI-GeneID:  100063318 NCBI-ProteinID:  XP_023507944 Ensembl:  ENSECAG00000006771 VGNC:  21843 LinkDB All DBs Position 11 AA seq 706 aa AA seqDB search MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVFICRKGFIKTDIIHSITVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKH KFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRI YLKAEVADEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQ WNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEE GEYYNVPIPEGDEEGNMELRQKFEKAKLGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFL MVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQ LHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYR DLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWW AYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLG CGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVTFCTKMHWLQWASRPSCGKGAENF DKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFLHPILQSAV NT seq 2121 nt NT seq  +upstreamnt  +downstreamnt atggctgacgttttcccggccaacgactccacggcgtctcaggacgtggccaaccgcttc gcccgcaaaggggcgctgagacagaagaacgtgcacgaggtgaaggaccacaaattcatc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt gggaaacaaggcttccagtgccaagtttttatatgcagaaagggcttcattaaaactgac atcattcattcaatcacagtttgctgctttgtggtccacaagaggtgccatgaatttgtt actttttcttgtccgggtgcggataagggacccgacactgatgaccccaggagcaagcac aagtttaaaatccacacttacggaagccccaccttctgtgatcactgtgggtcattgctg tatggacttatccatcaagggatgaaatgtgacacctgtgatatgaatgtgcacaagcag tgtgtgataaatgtccccagcctctgcgggatggaccacacagagaagagagggcggatc tacctgaaggcggaggttgccgatgaaaagctccatgtcacagtacgagatgcaaaaaat ctaattcctatggatccaaatgggctttcagatccttatgtgaagctgaaacttattcct gatcccaagaatgaaagcaaacaaaaaaccaaaaccatccgctccacactaaacccccag tggaatgagtcctttaccttcaaattaaaaccttcggacaaagaccgacgactctctgta gaaatctgggactgggaccgaacaaccaggaatgacttcatgggctccctttcctttgga gtttcggagctgatgaagatgccggccagtggatggtacaagttgctcaaccaagaagaa ggtgagtactacaacgtacccattccagaaggggacgaagaaggaaacatggagctcagg cagaaattcgagaaagccaagcttggccccgctggtaacaaagtgatcagtccttcagaa gacaggcgacaaccttctaacaaccttgacagagtgaaactcaccgacttcaatttcctc atggtgctggggaagggcagttttgggaaggtgatgcttgctgacaggaagggaacagaa gagctgtatgctatcaaaatcctgaagaaggacgtggtgattcaagatgacgatgtggag tgcaccatggtggaaaagcgagtcctggccctgcttgacaagcccccgttcctgacgcag ctgcactcctgcttccagacggtggatcgactatacttcgtcatggaatacgtcaatggc ggggacctcatgtaccacattcagcaagtaggaaaatttaaggaaccacaagcagtattc tatgcggctgagatttccattggattgttctttcttcataaaagaggaatcatttatagg gatctgaagttagacaatgtcatgctggattcggaaggacatatcaagattgctgatttt gggatgtgcaaggaacacatgatggatggagtcacgaccaggaccttctgtgggactcca gattatattgccccagagataatcgcttatcagccatatggaaaatccgtggactggtgg gcctatggcgtcctattgtatgaaatgctggcagggcagcctccatttgatggcgaagat gaagacgaactgtttcagtctataatggagcacaacgtttcttaccccaaatccttgtcc aaggaggccgtttccatctgcaaaggactgatgaccaaacaccccggcaagcggctgggc tgtgggcccgagggcgagagggacgtgcgagaacatgccttcttccggaggatcgactgg gagaaactggagaacagggagatccagccgccattcaagcccaaagtgactttctgtacc aaaatgcactggcttcagtgggcatccaggccttcgtgtggcaaaggagcagaaaacttc gacaagttcttcacacgagggcaacccgtgttaacgccgcctgatcagctggtcattgct aacatagatcagtctgattttgaagggttctcgtatgtcaacccccagtttctgcacccc atcttacaaagcgcagtatga

Equus caballus (horse): 100069215 Help Entry 100069215         CDS       T01058                                  Gene name PRKCB Definition (RefSeq) protein kinase C beta type isoform X1   KO K19662   classical protein kinase C beta type [EC:2.7.11.13] Organism ecb  Equus caballus (horse) Pathway ecb01521   EGFR tyrosine kinase inhibitor resistance ecb04010   MAPK signaling pathway ecb04012   ErbB signaling pathway ecb04014   Ras signaling pathway ecb04015   Rap1 signaling pathway ecb04020   Calcium signaling pathway ecb04062   Chemokine signaling pathway ecb04064   NF-kappa B signaling pathway ecb04066   HIF-1 signaling pathway ecb04070   Phosphatidylinositol signaling system ecb04071   Sphingolipid signaling pathway ecb04150   mTOR signaling pathway ecb04270   Vascular smooth muscle contraction ecb04310   Wnt signaling pathway ecb04370   VEGF signaling pathway ecb04510   Focal adhesion ecb04540   Gap junction ecb04613   Neutrophil extracellular trap formation ecb04650   Natural killer cell mediated cytotoxicity ecb04662   B cell receptor signaling pathway ecb04666   Fc gamma R-mediated phagocytosis ecb04670   Leukocyte transendothelial migration ecb04713   Circadian entrainment ecb04720   Long-term potentiation ecb04723   Retrograde endocannabinoid signaling ecb04724   Glutamatergic synapse ecb04725   Cholinergic synapse ecb04726   Serotonergic synapse ecb04727   GABAergic synapse ecb04728   Dopaminergic synapse ecb04730   Long-term depression ecb04750   Inflammatory mediator regulation of TRP channels ecb04911   Insulin secretion ecb04912   GnRH signaling pathway ecb04916   Melanogenesis ecb04918   Thyroid hormone synthesis ecb04919   Thyroid hormone signaling pathway ecb04921   Oxytocin signaling pathway ecb04925   Aldosterone synthesis and secretion ecb04928   Parathyroid hormone synthesis, secretion and action ecb04929   GnRH secretion ecb04931   Insulin resistance ecb04933   AGE-RAGE signaling pathway in diabetic complications ecb04935   Growth hormone synthesis, secretion and action ecb04960   Aldosterone-regulated sodium reabsorption ecb04961   Endocrine and other factor-regulated calcium reabsorption ecb04970   Salivary secretion ecb04971   Gastric acid secretion ecb04972   Pancreatic secretion ecb04973   Carbohydrate digestion and absorption ecb05017   Spinocerebellar ataxia ecb05022   Pathways of neurodegeneration - multiple diseases ecb05031   Amphetamine addiction ecb05032   Morphine addiction ecb05140   Leishmaniasis ecb05143   African trypanosomiasis ecb05146   Amoebiasis ecb05161   Hepatitis B ecb05163   Human cytomegalovirus infection ecb05164   Influenza A ecb05170   Human immunodeficiency virus 1 infection ecb05171   Coronavirus disease - COVID-19 ecb05200   Pathways in cancer ecb05205   Proteoglycans in cancer ecb05206   MicroRNAs in cancer ecb05214   Glioma ecb05223   Non-small cell lung cancer ecb05225   Hepatocellular carcinoma ecb05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ecb00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100069215 (PRKCB)    04012 ErbB signaling pathway     100069215 (PRKCB)    04014 Ras signaling pathway     100069215 (PRKCB)    04015 Rap1 signaling pathway     100069215 (PRKCB)    04310 Wnt signaling pathway     100069215 (PRKCB)    04370 VEGF signaling pathway     100069215 (PRKCB)    04064 NF-kappa B signaling pathway     100069215 (PRKCB)    04066 HIF-1 signaling pathway     100069215 (PRKCB)    04020 Calcium signaling pathway     100069215 (PRKCB)    04070 Phosphatidylinositol signaling system     100069215 (PRKCB)    04071 Sphingolipid signaling pathway     100069215 (PRKCB)    04150 mTOR signaling pathway     100069215 (PRKCB)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100069215 (PRKCB)    04540 Gap junction     100069215 (PRKCB)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     100069215 (PRKCB)    04650 Natural killer cell mediated cytotoxicity     100069215 (PRKCB)    04662 B cell receptor signaling pathway     100069215 (PRKCB)    04666 Fc gamma R-mediated phagocytosis     100069215 (PRKCB)    04670 Leukocyte transendothelial migration     100069215 (PRKCB)    04062 Chemokine signaling pathway     100069215 (PRKCB)   09152 Endocrine system    04911 Insulin secretion     100069215 (PRKCB)    04929 GnRH secretion     100069215 (PRKCB)    04912 GnRH signaling pathway     100069215 (PRKCB)    04921 Oxytocin signaling pathway     100069215 (PRKCB)    04935 Growth hormone synthesis, secretion and action     100069215 (PRKCB)    04918 Thyroid hormone synthesis     100069215 (PRKCB)    04919 Thyroid hormone signaling pathway     100069215 (PRKCB)    04928 Parathyroid hormone synthesis, secretion and action     100069215 (PRKCB)    04916 Melanogenesis     100069215 (PRKCB)    04925 Aldosterone synthesis and secretion     100069215 (PRKCB)   09153 Circulatory system    04270 Vascular smooth muscle contraction     100069215 (PRKCB)   09154 Digestive system    04970 Salivary secretion     100069215 (PRKCB)    04971 Gastric acid secretion     100069215 (PRKCB)    04972 Pancreatic secretion     100069215 (PRKCB)    04973 Carbohydrate digestion and absorption     100069215 (PRKCB)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100069215 (PRKCB)    04961 Endocrine and other factor-regulated calcium reabsorption     100069215 (PRKCB)   09156 Nervous system    04724 Glutamatergic synapse     100069215 (PRKCB)    04727 GABAergic synapse     100069215 (PRKCB)    04725 Cholinergic synapse     100069215 (PRKCB)    04728 Dopaminergic synapse     100069215 (PRKCB)    04726 Serotonergic synapse     100069215 (PRKCB)    04720 Long-term potentiation     100069215 (PRKCB)    04730 Long-term depression     100069215 (PRKCB)    04723 Retrograde endocannabinoid signaling     100069215 (PRKCB)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100069215 (PRKCB)   09159 Environmental adaptation    04713 Circadian entrainment     100069215 (PRKCB)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100069215 (PRKCB)    05206 MicroRNAs in cancer     100069215 (PRKCB)    05205 Proteoglycans in cancer     100069215 (PRKCB)    05231 Choline metabolism in cancer     100069215 (PRKCB)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100069215 (PRKCB)    05214 Glioma     100069215 (PRKCB)    05223 Non-small cell lung cancer     100069215 (PRKCB)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     100069215 (PRKCB)    05022 Pathways of neurodegeneration - multiple diseases     100069215 (PRKCB)   09165 Substance dependence    05031 Amphetamine addiction     100069215 (PRKCB)    05032 Morphine addiction     100069215 (PRKCB)   09167 Endocrine and metabolic disease    04931 Insulin resistance     100069215 (PRKCB)    04933 AGE-RAGE signaling pathway in diabetic complications     100069215 (PRKCB)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100069215 (PRKCB)    05161 Hepatitis B     100069215 (PRKCB)    05171 Coronavirus disease - COVID-19     100069215 (PRKCB)    05164 Influenza A     100069215 (PRKCB)    05163 Human cytomegalovirus infection     100069215 (PRKCB)   09174 Infectious disease: parasitic    05146 Amoebiasis     100069215 (PRKCB)    05140 Leishmaniasis     100069215 (PRKCB)    05143 African trypanosomiasis     100069215 (PRKCB)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100069215 (PRKCB)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ecb01001]     100069215 (PRKCB) Enzymes [BR:ecb01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      100069215 (PRKCB) Protein kinases [BR:ecb01001]  Serine/threonine kinases: AGC group   PKC family [OT]    100069215 (PRKCB) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 Kinase-like CEP76-C2 APH Motif Other DBs NCBI-GeneID:  100069215 NCBI-ProteinID:  XP_023471875 VGNC:  51219 LinkDB All DBs Position 13 AA seq 673 aa AA seqDB search MADPAAGPAPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIEREVLIVVVRDA KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL SVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGGEGSEE LRQKFERAKISQGTKTPEEKTTNTISKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF RYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFS FVNSEFLKPEVKS NT seq 2022 nt NT seq  +upstreamnt  +downstreamnt atggctgacccggctgcggggccggcgccgagcgagggcgaggagagcacggtgcgcttc gcccgcaaaggcgccctccggcagaagaacgtgcacgaggtgaagaaccacaaattcacc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttc gggaagcaaggattccagtgccaagtctgctgttttgtcgtgcacaagcggtgccatgaa tttgtcactttctcctgcccaggcgcggacaagggcccagcctctgatgatccccggagc aaacacaagtttaagatccacacgtactccagccccacattttgtgaccactgtgggtca ctgctgtatggactcatccaccaggggatgaaatgtgacacctgcatgatgaacgtccac aagcgctgcgtgatgaacgtccccagcctctgcggcacggaccacacggagcgccgcggc cgcatctacatccaggcccacatcgagagggaagtcctcatcgttgtcgtaagagatgct aaaaaccttgtacctatggatcccaatggcttgtcagatccttacgtgaaactgaaactg attcctgaccccaaaagtgagagcaagcagaagaccaaaaccatcaagtgctccctcaac cctgagtggaatgagacgtttagattccagctgaaagaatcggacaaagacaggagactg tctgtagagatttgggattgggatctgaccagcaggaatgacttcatgggatctttgtcg tttgggatttctgaattgcagaaagctggtgttgatggctggtttaagttactgagccag gaggaaggcgagtacttcaacgtgcctgtgccgccggaaggaggcgagggcagtgaagag ctgcggcagaagttcgagagggccaagatcagtcaggggactaagactccagaagaaaag acgaccaacaccatatccaaatttgacaacaatgggaacagggaccggatgaagctgacc gattttaacttcctgatggtgctggggaaaggcagctttggcaaggtcatgctctcagag cgaaagggcacagatgagctctatgctgtgaagatcctcaagaaggatgtggtgatccaa gatgacgatgtggaatgcacgatggtggagaagcgggtgctggccctgcccgggaagccg ccgttcctgacccagctgcactcctgctttcagaccatggaccgcctgtactttgtgatg gagtatgtcaacgggggtgacctcatgtaccacatccaacaagttggccggtttaaggag cctcatgctgtattttacgctgcagaaattgccatcggtctgttcttcttacagagcaag ggcatcatttaccgtgacctaaaacttgataacgtgatgctagattcggagggccacatc aagatcgctgattttggcatgtgtaaggaaaacatctgggacggagtgacgaccaagaca ttctgtggcactccagactatatcgcccctgagataattgcttatcagccctatgggaag tccgtggattggtgggcattcggagtcttgctgtatgaaatgttggctgggcaggctccc tttgaaggggaggatgaggatgaactcttccagtccatcatggaacacaatgtggcttat ccgaagtccatgtccaaggaggctgtggccatctgcaaagggctgatgaccaaacaccca ggcaagcgtctgggttgtggacctgaaggcgaacgtgacatcaaagagcatgcattcttc cggtatattgactgggagaaacttgaacgcaaagagattcagcccccgtataagccaaaa gcctgtgggcgaaatgctgaaaacttcgacagatttttcacccgccatccaccagtccta acacctcctgaccaggaagtcatcaggaatattgaccaatcagaattcgaaggattttcc tttgttaactctgaatttttaaaacctgaagtcaagagctaa

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