KEGG   Escherichia coli O18 K1 H7 UTI89 (UPEC): UTI89_C0054
Entry
UTI89_C0054       CDS       T00338                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
eci  Escherichia coli O18:K1:H7 UTI89 (UPEC)
Pathway
eci00670  One carbon pool by folate
eci00790  Folate biosynthesis
eci01100  Metabolic pathways
eci01240  Biosynthesis of cofactors
Module
eci_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:eci00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    UTI89_C0054 (folA)
   00670 One carbon pool by folate
    UTI89_C0054 (folA)
Enzymes [BR:eci01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     UTI89_C0054 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: ABE05564
UniProt: Q1RGF0
Structure
LinkDB
Position
52324..52938
AA seq 204 aa
MRRVQGESVDSPAEYKIFLNIILAPVDDGLRFTYSGDNFFYREISMISLIAALAVDRVIG
MENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWV
KSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWES
VFSEFHDADAQNSHSYCFEILERR
NT seq 615 nt   +upstreamnt  +downstreamnt
atgcggcgagtccagggagagagcgtggactcgccagcagaatataaaattttcctcaac
atcatcctcgcaccagtcgacgacggtttacgctttacgtatagtggcgacaattttttt
tatcgggaaatctcaatgatcagtctgattgcggcgttagcggtagatcgcgttatcggc
atggaaaacgccatgccgtggaacctgcctgccgatctcgcctggtttaaacgcaacact
ttaaataaacccgtgattatgggccgccatacctgggaatccatcggtcgtccgttgcca
ggacgcaaaaatattatcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtg
aagtcggtggatgaagccattgcggcgtgtggtgacgtaccagaaatcatggtgattggc
ggcggtcgcgtttatgagcagttcctgccgaaagcgcaaaaactgtatctgacgcatatc
gacgcggaagtggaaggcgacacccatttcccggattacgagccggatgactgggaatcg
gtattcagtgaattccacgacgccgatgcgcagaactctcatagctattgctttgagatt
ctggagcggcggtaa

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