KEGG   Escherichia coli K-12 W3110: JW3359Help
Entry
JW3359            CDS       T00068                                 

Gene name
mrcA
Definition
(GenBank) fused penicillin-binding protein 1a murein transglycosylase and murein transpeptidase
  KO
K05366  penicillin-binding protein 1A [EC:2.4.1.129 3.4.16.4]
Organism
ecj  Escherichia coli K-12 W3110
Pathway
ecj00550  Peptidoglycan biosynthesis
ecj01100  Metabolic pathways
ecj01501  beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:ecj00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    JW3359 (mrcA)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    JW3359 (mrcA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:ecj01003]
    JW3359 (mrcA)
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:ecj01011]
    JW3359 (mrcA)
Enzymes [BR:ecj01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.129  peptidoglycan glycosyltransferase
     JW3359 (mrcA)
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.16  Serine-type carboxypeptidases
    3.4.16.4  serine-type D-Ala-D-Ala carboxypeptidase
     JW3359 (mrcA)
Glycosyltransferases [BR:ecj01003]
 Polysaccharide
  Bacterial polysaccharide
   JW3359 (mrcA)
Peptidoglycan biosynthesis and degradation proteins [BR:ecj01011]
 Peptidoglycan biosynthesis and degradation
  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
   JW3359 (mrcA)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Transgly PCB_OB Transpeptidase DUF3502 Tudor_4
Motif
Other DBs
NCBI-ProteinID: BAE77895
UniProt: P02918
LinkDB All DBs
Position
complement(4114993..4117545)
Genome map
AA seq 850 aa AA seqDB search
MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQIYSADGELIAQ
YGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGAST
ITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAA
QVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQF
DQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQ
QAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNNKITDTLKALPTYGPLLPAAVTSANPQ
QATAMLADGSTVALSMEGVRWARPYRSDTQQGPTPRKVTDVLQTGQQIWVRQVGDAWWLA
QVPEVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL
TLASMLNDVPISRWDASAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDY
AAEYLQRFGFPAQNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQG
GVIFEAKPKVACPECDIPVIYGDTQKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQA
LVAKTGAQEYAPHVINTPLAFLIKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTGTT
NSSKDAWFSGYGPGVVTSVWIGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAY
MKAVLEGVPEQPLTPPPGIVTVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTI
IDNGEAQELF
NT seq 2553 nt NT seq  +upstreamnt  +downstreamnt
gtgaagttcgtaaagtattttttgatccttgcagtctgttgcattctgctgggagcaggc
tcgatttatggcctataccgctacatcgagccacaactgccggatgtggcgacattaaaa
gatgttcgcctgcaaattccgatgcagatttacagcgccgatggcgagctgattgctcaa
tacggtgagaaacgtcgtattccggttacgttggatcaaatcccaccggagatggtgaaa
gcctttatcgcgacagaagacagccgcttctacgagcatcacggcgttgacccggtgggg
atcttccgtgcagcaagcgtggcgctgttctccggtcacgcgtcacaaggggcaagtacc
attacccagcagctggcgagaaacttcttcctcagtccagaacgcacgctgatgcgtaag
attaaggaagtcttcctcgcgattcgcattgaacagctgctgacgaaagacgagatcctc
gagctttatctgaacaagatttaccttggttaccgcgcctatggtgtcggtgctgcggca
caagtctatttcggaaaaacggtcgaccaactgacgctgaacgaaatggcggtgatagcc
gggctgccgaaagcgccttccaccttcaacccgctctactcgatggatcgtgccgtcgcg
cggcgtaacgtcgtgctgtcgcggatgctggatgaagggtatatcacccaacaacagttc
gatcagacacgcactgaggcgattaacgctaactatcacgcgccggagattgctttctct
gcgccgtacctgagcgaaatggtgcgccaggagatgtataaccgttatggcgaaagtgcc
tatgaagacggttatcgcatttacaccaccatcacccgcaaagtgcagcaggccgcgcag
caggcggtacgtaataacgtgctggactacgacatgcgccacggctatcgcggcccggca
aatgtgctgtggaaagtgggcgagtcggcgtgggataacaacaagattaccgatacgctg
aaggcgctgccaacctatggtccgctgctgcctgccgcagtcaccagcgccaatcctcag
caagcgacggcgatgctggcggacgggtcgaccgtcgcattgagtatggaaggcgttcgc
tgggcgcgtccttaccgttcggatactcagcaaggaccgacgccgcgtaaagtgaccgat
gttctgcaaacgggtcagcaaatctgggttcgtcaggttggcgatgcatggtggctggca
caagtgccggaagtgaactcggcgctggtgtcgatcaatccgcaaaacggtgccgttatg
gcgctggtcggtggctttgatttcaatcagagcaagtttaaccgcgccacccaggcactg
cgtcaggtgggttccaacatcaaaccgttcctctacaccgcggcgatggataaaggtctg
acgctggcaagtatgttgaacgatgtgccaatttctcgctgggatgcaagtgccggttct
gactggcagccgaagaactcaccaccgcagtatgctggtccaattcgcttacgtcagggg
ctgggtcagtcgaaaaacgtggtgatggtacgcgcaatgcgggcgatgggcgtcgactac
gctgcagaatatctgcaacgcttcggcttcccggcacaaaacattgtccacaccgaatcg
ctggcgctgggttcagcgtccttcaccccaatgcaggtggcgcgcggctacgcggtcatg
gcgaacggcggcttcctggtggacccgtggtttatcagcaaaattgaaaacgatcagggc
ggcgtgattttcgaagcgaaaccgaaagtagcctgcccggaatgcgatattccggtgatt
tacggtgatacgcagaaatcgaacgtgctggaaaataacgatgttgaagatgtcgctatc
tcccgcgagcagcagaatgtttctgtaccaatgccgcagctggagcaggcaaatcaggcg
ttagtggcgaagactggcgcgcaggagtacgcaccgcacgtcatcaacactccgctggca
ttcctgattaagagtgctttgaacaccaatatctttggtgagccaggctggcagggtact
ggctggcgtgcaggtcgtgatttgcagcgtcgcgatatcggcgggaaaaccgggaccact
aacagttcgaaagatgcgtggttctcgggttacggtccgggcgttgtgacctcggtctgg
attggctttgatgatcaccgtcgtaatctcggtcatacaacggcttccggagcgattaaa
gatcagatctcaggttacgaaggcggtgccaagagtgcccagcctgcatgggacgcttat
atgaaagccgttcttgaaggtgtgccggagcagccgctgacgccgccaccgggtattgtg
acggtgaatatcgatcgcagcaccgggcagttagctaatggtggcaacagccgcgaagag
tatttcatcgaaggtacgcagccgacacaacaggcagtgcacgaggtgggaacgaccatt
atcgataatggcgaggcacaggaattgttctga

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