KEGG   Escherichia coli O145 H28 RM13516 (EHEC): ECRM13516_4136Help
Entry
ECRM13516_4136    CDS       T03011                                 

Gene name
mrcA
Definition
(GenBank) Multimodular transpeptidase-transglycosylase
  KO
K05366  penicillin-binding protein 1A [EC:2.4.1.129 3.4.16.4]
Organism
ecoh  Escherichia coli O145:H28 RM13516 (EHEC)
Pathway
ecoh00550  Peptidoglycan biosynthesis
ecoh01100  Metabolic pathways
ecoh01501  beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:ecoh00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    ECRM13516_4136 (mrcA)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    ECRM13516_4136 (mrcA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:ecoh01003]
    ECRM13516_4136 (mrcA)
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:ecoh01011]
    ECRM13516_4136 (mrcA)
Enzymes [BR:ecoh01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.129  peptidoglycan glycosyltransferase
     ECRM13516_4136 (mrcA)
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.16  Serine-type carboxypeptidases
    3.4.16.4  serine-type D-Ala-D-Ala carboxypeptidase
     ECRM13516_4136 (mrcA)
Glycosyltransferases [BR:ecoh01003]
 Polysaccharide
  Bacterial polysaccharide
   ECRM13516_4136 (mrcA)
Peptidoglycan biosynthesis and degradation proteins [BR:ecoh01011]
 Peptidoglycan biosynthesis and degradation
  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
   ECRM13516_4136 (mrcA)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Transgly PCB_OB Transpeptidase DUF3502 Tudor_4
Motif
Other DBs
NCBI-ProteinID: AHG16754
LinkDB All DBs
Position
4075403..4077955
Genome map
AA seq 850 aa AA seqDB search
MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQIYSADGELIAQ
YGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGAST
ITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAA
QVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQF
DQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQ
QAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNNKITDTLKALPTYGPLLPAAVTSANPQ
EATAMLADGSTVALSMEGVRWARPYRSDTQQGPTPRKVTDVLQTGQQIWVRQVGDAWWLA
QVPEVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL
TLASMLNDVPISRWDAGAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDY
AAEYLQRFGFPAQNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQG
GVIFEAKPKVACPECDIPVIYGDTQKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQA
LVAKTGAQEYAPHVINTPLAFLIKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTGTT
NSSKDAWFSGYGPGVVTSVWIGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAY
MKAVLEGVPEQPLTPPPGIVTVKIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTI
IDNGEAQELF
NT seq 2553 nt NT seq  +upstreamnt  +downstreamnt
gtgaagttcgtaaagtattttttgatccttgcagtctgttgcattctgctgggagcaggc
tcgatttatggcctataccgctacatcgagccacaactgccggatgtggcgacattaaaa
gatgttcgcctgcaaattccgatgcagatttacagcgccgatggcgagctgattgctcaa
tacggtgagaaacgtcgtattccggttacgctggatcaaatcccaccggagatggtgaaa
gcctttatcgcgacggaagacagccgcttctacgagcatcacggcgttgacccggtgggg
atcttccgtgcagcaagcgtggcgctgttctccggccacgcgtcacaaggggcgagtacc
attacccagcagctggcgagaaacttcttcctaagtccagaacgcacgctgatgcgtaag
attaaggaagtcttcctcgcgattcgcattgaacagctgctgacgaaagacgagatcctc
gagctttatctgaacaagatttaccttggttaccgcgcctatggtgtcggtgctgcggca
caagtctatttcggaaaaacggtcgaccaactgacgctgaacgaaatggcggtgatagcc
gggctgccgaaagcgccttccaccttcaacccgctctactcgatggatcgtgccgtcgcg
cggcgtaacgtcgtgctatcgcggatgctggatgaagggtatatcacccaacaacagttc
gatcagacacgcactgaggcgattaacgctaactatcacgcgccggagattgctttttct
gcgccgtacctgagcgaaatggtgcgccaggagatgtataaccgttatggcgaaagtgcc
tatgaagacggttatcgcatttacaccaccatcacccgcaaagtgcagcaggccgcacag
caggcggtacgtaataacgtgctggactacgacatgcgccacggctatcgcggcccggca
aatgtgctgtggaaagtgggcgagtcggcgtgggataacaacaagattaccgatacgctg
aaggcgctgccgacctatggtccgctgctgcctgccgcagtcaccagcgccaatcctcag
gaagcgacggcgatgctggcggacgggtcgaccgtcgcattgagtatggaaggcgttcgc
tgggcgcgtccttaccgttcggatactcagcagggaccgacgccgcgtaaagtgaccgat
gttctgcaaacgggtcagcaaatctgggttcgtcaggttggcgatgcatggtggctggca
caagtgccggaagtgaactcggcgctggtgtcgatcaatccgcaaaatggtgccgttatg
gcgctggtcggtggctttgatttcaatcagagcaagtttaaccgcgccacccaggcactg
cgtcaggtaggttccaacatcaaaccgttcctctacaccgcggcgatggataaaggtctg
acgctggcaagtatgttgaacgatgtgccaatttctcgctgggatgcaggtgccggttct
gactggcagccgaagaactcaccacctcagtatgccggtccaattcgcttacgtcagggg
ctgggtcagtcgaaaaacgtggtgatggtacgcgcaatgcgggcgatgggcgtcgactac
gccgcagaatatctgcaacgcttcggcttcccggcgcaaaacattgtccacaccgaatcg
ctggcgctgggttcagcgtccttcactccaatgcaggtggcgcgcggctacgcggtcatg
gcgaacggcggcttcctggtggacccgtggtttatcagcaaaattgaaaacgatcagggc
ggcgtgattttcgaagcgaaaccgaaagtagcctgcccggaatgtgatattccggtgatt
tacggtgatacgcagaaatcgaacgtgctggaaaataacgatgttgaagatgtcgctatc
tcccgcgagcagcagaatgtttctgtaccaatgccgcagctggagcaggcaaaccaggcg
ttagttgcgaagactggcgcgcaggagtatgcaccgcacgtcatcaacactccgctggca
ttcctgattaagagtgctttgaacaccaatatctttggtgagccaggctggcagggtacc
ggctggcgtgcaggtcgtgatttgcagcgtcgcgatatcggcgggaaaaccgggaccact
aacagttcgaaagatgcgtggttctcgggttacggtccgggcgttgtgacctcggtctgg
attggctttgatgatcaccgtcgtaatctcggtcatacaacggcttccggagcgattaaa
gatcagatatcaggttacgaaggcggtgccaagagcgcccagcctgcatgggacgcttat
atgaaagccgttcttgaaggtgtgccggagcagccgctgacgccgccgccgggtattgtg
acggtgaaaatcgatcgcagcaccgggcagttagctaatggtggcaacagccgcgaagag
tatttcatcgaaggtacgcagccgacacaacaggcggtgcacgaggtgggaacgaccatt
atcgataatggcgaggcacaggaattgttctga

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