KEGG   Escherichia coli K-12 MDS42: ECMDS42_0085Help
Entry
ECMDS42_0085      CDS       T02541                                 

Gene name
ddlB
Definition
(GenBank) D-Alanine:D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
ecok  Escherichia coli K-12 MDS42
Pathway
ecok00473  D-Alanine metabolism
ecok00550  Peptidoglycan biosynthesis
ecok01100  Metabolic pathways
ecok01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:ecok00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00473 D-Alanine metabolism
    ECMDS42_0085 (ddlB)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    ECMDS42_0085 (ddlB)
 09160 Human Diseases
  09175 Drug resistance: Antimicrobial
   01502 Vancomycin resistance
    ECMDS42_0085 (ddlB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:ecok01011]
    ECMDS42_0085 (ddlB)
Enzymes [BR:ecok01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     ECMDS42_0085 (ddlB)
Peptidoglycan biosynthesis and degradation proteins [BR:ecok01011]
 Precursor biosynthesis
  Amino acid ligase
   ECMDS42_0085 (ddlB)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N CPSase_L_D2 ATP-grasp_4 ATP-grasp ATPgrasp_YheCD TTL ATPgrasp_ST GARS_A RimK
Motif
Other DBs
NCBI-ProteinID: BAL37404
LinkDB All DBs
Structure
PDB: 

Position
97058..97978
Genome map
AA seq 306 aa AA seqDB search
MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFI
ALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRA
EFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIE
KWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQAL
VLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVR
ILELAD
NT seq 921 nt NT seq  +upstreamnt  +downstreamnt
atgactgataaaatcgcggtcctgttgggtgggacctccgctgagcgggaagtttctctg
aattctggcgcagcggtgttagccggactgcgtgaaggcggtattgacgcgtatcctgtc
gacccgaaagaagtcgacgtgacgcaactgaagtcgatgggctttcagaaagtgtttatc
gcgctacacggtcgcggcggtgaagatggtacgctgcaggggatgctcgagctgatgggc
ttgccttataccggaagcggagtgatggcatctgcgctttcaatggataaactacgcagc
aaacttctatggcaaggtgccggtttaccggtcgcgccgtgggtagcgttaacccgcgca
gagtttgaaaaaggcctgagcgataagcagttagcagaaatttctgctctgggtttgccg
gttatcgttaagccgagccgcgaaggttccagtgtgggaatgtcaaaagtagtagcagaa
aatgctctacaagatgcattaagattggcatttcagcacgatgaagaagtattgattgaa
aaatggctaagtgggccggagttcacggttgcgatactcggtgaagaaattttaccgtca
atacgtattcaaccgtccggaaccttctatgattatgaggcgaagtatctctctgatgag
acacagtatttctgccccgcaggtctggaagcgtcacaagaggccaatttgcaggcatta
gtgctgaaagcatggacgacgttaggttgcaaaggatggggacgtattgacgttatgctg
gacagcgatggacagttttatctgctggaagccaatacctcaccgggtatgaccagccac
agcctggtgccgatggcggcacgtcaggcaggtatgagcttctcgcagttggtagtacga
attctggaactggcggactaa

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