KEGG   Escherichia coli O45 K1 H7 S88 (ExPEC): ECS88_0095Help
Entry
ECS88_0095        CDS       T00830                                 

Gene name
ddlB
Definition
(GenBank) D-alanine:D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
ecz  Escherichia coli O45:K1:H7 S88 (ExPEC)
Pathway
ecz00473  D-Alanine metabolism
ecz00550  Peptidoglycan biosynthesis
ecz01100  Metabolic pathways
ecz01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:ecz00001]
 Metabolism
  Metabolism of other amino acids
   00473 D-Alanine metabolism
    ECS88_0095 (ddlB)
  Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    ECS88_0095 (ddlB)
 Human Diseases
  Drug resistance
   01502 Vancomycin resistance
    ECS88_0095 (ddlB)
Enzymes [BR:ecz01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     ECS88_0095 (ddlB)
Peptidoglycan biosynthesis and degradation proteins [BR:ecz01011]
 Precursor biosynthesis
  Amino acid ligase
   ECS88_0095 (ddlB)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N CPSase_L_D2 ATP-grasp_4 ATP-grasp ATPgrasp_Ter ATPgrasp_YheCD TTL ATPgrasp_ST GARS_A
Motif
Other DBs
NCBI-ProteinID: CAR01461
UniProt: B7MAL5
LinkDB All DBs
Structure
PDB: 

Position
104675..105595
Genome map
AA seq 306 aa AA seqDB search
MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFI
ALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRA
EFEKGLNDKQLAEISSLGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIE
KWLSGPEFTIAILGEEILPSIRIQPAGTFYDYEAKYLSDETQYFCPAGLEASQEANLQAL
VLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVR
ILELAD
NT seq 921 nt NT seq  +upstreamnt  +downstreamnt
atgactgataaaatcgcggtcctgttgggcgggacctccgctgagcgggaagtttctctg
aattctggcgcagcggtgttagccgggctgcgtgaaggcggtattgacgcgtatcctgtc
gacccgaaagaagtcgacgtgacgcaactgaagtcgatgggttttcagaaagtgtttatc
gcgctacacggtcgcggcggtgaagatggtacgctgcagggcatgctcgagctgatgggc
ttgccttataccggcagcggagtgatggcatctgcgctttcaatggataaactacgcagc
aaacttctgtggcagggtgccggtttaccggtcgcgccgtgggtagcgttaacccgcgca
gagtttgaaaaaggccttaacgataagcagttagcagaaatttcttctctgggtttgccg
gttatcgttaagccgagccgcgaaggttccagtgtgggaatgtcaaaagtagtagcagaa
aatgctctacaagatgcattaagattggcatttcagcacgatgaagaagtattgattgaa
aaatggctaagtgggccggagttcacgattgcgatactcggtgaagaaattttaccgtca
atacgtattcaaccggccggaaccttctatgattatgaggcgaagtatctctctgatgag
acacagtatttctgccccgcaggtctggaagcgtcacaagaggccaatttgcaggcatta
gtgctaaaagcatggacgacgttaggttgcaaaggatggggacgtattgacgttatgctg
gacagtgatggacagttttatctgctggaagccaatacctcaccgggtatgaccagccac
agtctggtgccgatggcggcacgtcaggcaggtatgagcttctcgcagttggtagtacga
attctggaactggcggactaa

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