Edwardsiella sp. LADL05-105: AAZ33_02675
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Entry
AAZ33_02675 CDS
T04005
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
edl
Edwardsiella sp. LADL05-105
Pathway
edl00260
Glycine, serine and threonine metabolism
edl00261
Monobactam biosynthesis
edl00270
Cysteine and methionine metabolism
edl00300
Lysine biosynthesis
edl01100
Metabolic pathways
edl01110
Biosynthesis of secondary metabolites
edl01120
Microbial metabolism in diverse environments
edl01230
Biosynthesis of amino acids
Module
edl_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
edl_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
edl_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
edl00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
AAZ33_02675 (thrA)
00270 Cysteine and methionine metabolism
AAZ33_02675 (thrA)
00300 Lysine biosynthesis
AAZ33_02675 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
AAZ33_02675 (thrA)
Enzymes [BR:
edl01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
AAZ33_02675 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
AAZ33_02675 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
AKR76789
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All DBs
Position
583575..586037
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERVFSVADILESKASQGQVAAVLSAPARITNHLVALIERTIAGQDI
QPILGDAEKIFSDLIDGLALAQPGFDAAPLRLRVSQEFGQIRQVLHGIALLGQCPDGVNA
ALICRGEALSIAIMAALLRARGCPVTVIDPVNSLLARGGYLESSVDIAESARRIAAQVIP
TDSLILMAGFTAGNERGELVVLGRNGSDYSAAVLAACLRAECCEIWTDVDGVYTCDPRLV
PDARLLESMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTANPQAPGTLIGAQRR
ADDALPVKGITHLNHMAMLNVSGPGMKGMVGMAARVFAVMSRSGISVVLITQSSSEYSIS
FCVPQGELARACQALQDEFFLELKDGLLEPLDVIEHLAIISVVGDGMRTQRGISAKFFSA
LARANINIVAIAQGSSERSISVVVNNDAATTAVRVTHQMLFNTDQVIEVFVIGVGGVGGA
LLAQIERQQAWLKSKHIDLRVCGIANSRALLTHVHGIDMANWRGALEQASQPFNLGRLMR
LVNEYHLLNPVIVDCTSSQALADQYADFLGNGFHVVTPNKKANTASLDYYRLLRQKAAGS
QRKFLYDTNVGAGLPVIENLQNLLSAGDELQRFCGILSGSLSFIFGRLEEGATFSQATRE
ARQLGYTEPDPRDDLSGMDVARKLLILAREAGYALELDDICVEPVLPAAFDARGDVDTFL
ANLAQADDAFSARVAAAQARGCVLRYVGEIDQGRCAVRIAEVDSDDALYKVKNGENALTF
YSRYYQPLPMVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgagagtattaaaattcggtggcacgtcggtcgccaacgcggagcgggtcttcagcgtt
gccgatattttggagagtaaggcctcacagggacaggtcgccgccgtgctttccgccccg
gcccgtatcaccaaccatctggttgcgctgattgaacgcaccatcgctgggcaagatatc
cagccgatactcggcgacgccgagaagatttttagcgatctgatcgatggcttagccctg
gcgcagccgggcttcgacgccgcgccgctgcgtctgcgggtgtcccaggagtttggccag
atccgtcaggtgctgcacggcatcgccctgctgggtcagtgtccggacggcgtcaacgcg
gcgctgatttgccgcggagaggcgctctccatcgcgatcatggcggcgctgctgcgggcg
cgcggatgtccggtgaccgtgatcgatccggtcaacagcctgctggcccgcggtggctat
ctggagtccagcgtcgatatcgcggagtccgcccgccgtattgccgcccaggtgatcccg
accgacagcctgatcctgatggcgggcttcaccgccggtaacgagcgcggcgagctggtg
gtgctggggcgcaacggctcagactattcggcggcggtgttggccgcctgcctgcgcgca
gagtgctgtgagatctggacggacgttgacggcgtctatacctgcgatccgcgtctggtt
ccagacgcccgtctgctggagtcgatgtcctaccaagaggcgatggagctctcctacttt
ggcgccaaggtgctgcacccgcgcaccattgcaccgatcgcccagtttcaaatcccctgc
ctgatcaaaaatactgccaatccacaggcgcccggcaccctgatcggcgcgcagcgccgc
gccgacgacgcgctgccggtgaaggggatcacccatctgaaccatatggcgatgctcaac
gtctcgggcccggggatgaaggggatggtcggcatggcggcgcgggtcttcgctgtgatg
tcgcgcagcggtatttccgtggtgttgataacccagtcctcctctgaatacagcatcagc
ttttgtgtaccgcagggggagctggcgcgggcctgccaggcgctgcaggatgagttcttc
ctggagcttaaggatggcctgctggagccgctggatgttatcgagcatctggcgatcatc
tcggtggtcggcgacggtatgcggacccagcgcggcatctcggccaagttcttttcggct
ctggcgcgggcgaacatcaacattgtcgcgattgcgcagggctcctctgagcgctcgatc
tccgtcgtggtgaacaatgatgcggcgacgaccgccgtgcgtgtgacgcaccagatgctg
ttcaacaccgatcaggtgatcgaggtgtttgttatcggcgtgggcggcgtggggggcgcg
ctgctggcgcagattgagcgtcagcaggcctggctaaaaagtaagcatatcgatctgcgg
gtgtgcggcatcgcgaactcccgagcgctgctgacccatgtacacggtatcgatatggcg
aactggcgcggggcgctggagcaggcctcgcagccgtttaacctggggcgcctgatgcgc
ctggtgaacgagtatcacctgctgaatccggtgatcgtcgactgtacctccagccaggcg
ttggccgatcagtacgctgacttcctcggtaatggttttcacgtggtgacgccgaataaa
aaggccaatacggcttccctggattattaccgcctgctgcgtcagaaggcggcgggcagc
cagcgcaagtttctctacgataccaacgtcggggccgggctgccggtgattgaaaacctg
caaaatctgctgagcgccggcgatgagctgcagcggttctgcggcattctctccggttcg
ctgtcgtttatctttggccgcttggaggagggggcgaccttctcacaggcaacccgtgaa
gcgcgtcagctgggctataccgaaccggatccgcgtgacgatctctccggcatggacgtg
gcgcgcaagctgctgatcctggcacgtgaggcgggatatgccctggagctggacgatatc
tgcgtcgagccggtgctgccggcggcgttcgatgcccgcggtgacgtcgatacgttcctc
gccaatctggcgcaggcggatgacgcgtttagcgcgagggtcgccgctgcgcaagcgcgt
ggctgcgtgctgcgctacgtcggcgagatcgatcaggggcgctgcgcggtgcgcattgcg
gaggtggacagcgatgatgcgctgtataaggttaaaaatggcgaaaacgccctgacgttt
tacagccgttactatcagccgctgccgatggtgctacgcggctatggcgcgggtaacgat
gtcaccgccgccggcgtctttgccgatctgctgcggaccttgtcatggaagctgggagtt
taa
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