Enhydra lutris kenyoni (northern sea otter): 111142881
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Entry
111142881 CDS
T05871
Definition
(RefSeq) tyrosine-protein kinase JAK1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk01521
EGFR tyrosine kinase inhibitor resistance
elk04151
PI3K-Akt signaling pathway
elk04217
Necroptosis
elk04380
Osteoclast differentiation
elk04550
Signaling pathways regulating pluripotency of stem cells
elk04621
NOD-like receptor signaling pathway
elk04630
JAK-STAT signaling pathway
elk04658
Th1 and Th2 cell differentiation
elk04659
Th17 cell differentiation
elk05140
Leishmaniasis
elk05145
Toxoplasmosis
elk05152
Tuberculosis
elk05160
Hepatitis C
elk05161
Hepatitis B
elk05162
Measles
elk05163
Human cytomegalovirus infection
elk05164
Influenza A
elk05165
Human papillomavirus infection
elk05166
Human T-cell leukemia virus 1 infection
elk05167
Kaposi sarcoma-associated herpesvirus infection
elk05168
Herpes simplex virus 1 infection
elk05169
Epstein-Barr virus infection
elk05171
Coronavirus disease - COVID-19
elk05200
Pathways in cancer
elk05203
Viral carcinogenesis
elk05212
Pancreatic cancer
elk05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
111142881
04151 PI3K-Akt signaling pathway
111142881
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
111142881
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
111142881
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
111142881
04658 Th1 and Th2 cell differentiation
111142881
04659 Th17 cell differentiation
111142881
09158 Development and regeneration
04380 Osteoclast differentiation
111142881
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111142881
05203 Viral carcinogenesis
111142881
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
111142881
09162 Cancer: specific types
05212 Pancreatic cancer
111142881
09171 Infectious disease: bacterial
05152 Tuberculosis
111142881
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
111142881
05161 Hepatitis B
111142881
05160 Hepatitis C
111142881
05171 Coronavirus disease - COVID-19
111142881
05164 Influenza A
111142881
05162 Measles
111142881
05168 Herpes simplex virus 1 infection
111142881
05163 Human cytomegalovirus infection
111142881
05167 Kaposi sarcoma-associated herpesvirus infection
111142881
05169 Epstein-Barr virus infection
111142881
05165 Human papillomavirus infection
111142881
09174 Infectious disease: parasitic
05145 Toxoplasmosis
111142881
05140 Leishmaniasis
111142881
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111142881
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
elk01001
]
111142881
Enzymes [BR:
elk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
111142881
Protein kinases [BR:
elk01001
]
Non-receptor tyrosine kinases
JAK family [OT]
111142881
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
SH2
DUF4079
Motif
Other DBs
NCBI-GeneID:
111142881
NCBI-ProteinID:
XP_022351982
UniProt:
A0A2Y9ITG3
LinkDB
All DBs
Position
Unknown
AA seq
1153 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLSDREPLRLGSGEYTAEEI
CIRAAQECCISPLCHNLFALYDENSKLWYAPNRAITVDDKTSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
WFHPNDSGNVLYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR
EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLIDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSEVLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGT
LVDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL
LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI
MRDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS
GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD
YSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPLHCPDEVYQLMRKCWEFQPSNRTT
FQNLIEGFEALLK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaagacggaggtgaatctggaggcccctgagccaggagtggaagtgctcttc
tatctttctgatagggagcccctccggctgggcagcggagagtacaccgcggaggagatc
tgcatcagggcggcgcaggaatgctgtatctctccactgtgtcacaacctctttgccctg
tatgatgagaacagcaagctctggtatgccccgaatcgcgccatcactgttgacgacaag
acatccctccggctccactaccggatgaggttctatttcaccaactggcatgggaccaat
gataatgagcagtccgtatggcgacattctccaaagaagcagaaaaatggctatgagaaa
aaaaaagtcccagatgcaacccctctccttgatgccagttctttggaatatctgtttgct
cagggacagtatgatttggtcaaatgtctggctcccattcgagaccccaagaccgagcaa
gatgggcacgatattgagaatgagtgtctgggaatggctgtcctggccatctcccactac
gccatgatgaagaagatgcagttgccagaactgcccaaggacatcagctacaagcgatat
attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata
aataatgttttcaaggatttcctgaaggaatttaacaacaagactatttgtgacagcagt
gtatctactcatgacctaaaggtgaagtacttagccaccttggaaacactgacaaaacat
tatggcgcagaaatatttgagacttccatgttactgatttcatcagaaaatgagatgaat
tggtttcatccgaacgacagtggaaatgttctctactatgaagtgatggtaactggaaat
cttggaatccagtggagacagaaaccaaacgttgttcctgttgaaaaggaaaaaaacaaa
ctgaaacggaaaaaactggaaaataaacacaagaaggatgaggagaaaaacaaaatccgg
gaggagtggaacaatttttcttacttccctgaaatcactcacattgtaataaaggagtct
gtggtcagcatcaataaacaggacaacaaaaaaatggaactgaagctctcgtcccatgaa
gaggccttgtcctttgtgtccctgatagatggctacttccggctcacagcagatgcccat
cattacctctgcaccgatgtggctcccccattgatcgtccacaacatacagaatggttgt
cacggtccaatctgcacggaatatgccatcaataagttgcggcaagaaggaagcgaggag
gggatgtatgtgctgaggtggagctgtactgactttgacaatatcctcatgacggtcacc
tgctttgagaaatctgaggtgctgggaggccagaagcagttcaagaactttcagatcgaa
gtgcagaagggccgctatagcctgcacggctcggaccgcagcttccccagcctgggggac
ctgatgagccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtgctgaag
cgctgctgccagcccaagccccgagagatctccaatctgctggtggctacgaagaaagcc
caggagtggcagcctgtctaccccatgagccagctgagttttgaccgaatcctcaagaaa
gatatcgtgcaaggtgagcatctcgggagaggcacacggacacacatctactccggcacc
ctggtggattacaaggatgacgaagggacttccgaagagaagagaataaaagtgatcctc
aaagtcttagaccccagccacagggacatttctctggccttctttgaagcagccagcatg
atgaggcaggtctcccacaaacacatcgtgtacctctatggtgtctgtgtccgagatgtg
gagaatatcatggtggaggagtttgtggaaggggggccccttgatctcttcatgcatcgg
aaaagcgatgtcctcactacaccatggaagttcaaagttgccaaacagctagccagcgcc
ctcagttacttggaggacaaagacctggtccacggaaatgtgtgcacgaaaaaccttctc
ctggcccgtgagggcattgacagcgagtgtggcccgttcatcaagctcagtgaccctggc
atccccattaccgtgctgtccaggcaagagtgcatagaacgaatcccgtggattgctccc
gagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagctttggaacc
acactctgggaaatctgctacaatggcgagatccctctgaaagacaagaccctgattgag
aaagagagattctacgaaagccggtgccggccagtgacgccatcttgtaaggagctggct
gacctcatgacacgctgcatgaactatgaccccaaccagagacccttcttccgagccatc
atgagagacatcaacaaactagaagagcagaatccagacattgtttctgaaagaaagccg
gcaaccgaagtagatcccacacattttgaaaagcggttcttgaagaggatccgtgacttg
ggagagggccactttgggaaggttgagctctgcaggtatgaccctgagggggacaatact
ggggagcaagtggcggtgaagtccctgaagcccgagagtggaggcaaccacatagctgat
ctgaagaaggaaattgaaatcctaaggaacctctatcacgagaacattgtgaaatacaaa
ggcatctgtacggaagacggaggaaatggtattaagctcatcatggaatttctgccttca
ggaagccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcaatta
aaatacgccgttcagatttgtaaggggatggactatttgggttctcggcagtacgttcac
cgggacttggcagcaagaaatgtcctcgtcgagagtgagcaccaagtgaaaattggagac
tttggtttgaccaaagcaatcgaaactgacaaagagtactacaccgtcaaggatgatcgg
gacagccctgtgttttggtatgctcccgaatgtttaattcagtgtaaattttacatcgcc
tctgatgtctggtcgtttggagtgactctgcatgagttgcttacttactgcgactcagat
tacagccccatggcgttgttcctgaaaatgataggcccaactcatggccagatgacagtc
acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacttcactgtcca
gatgaggtttatcaacttatgagaaaatgctgggagttccaaccatccaatcggacaact
tttcagaaccttatcgaaggatttgaagcacttttaaaataa
DBGET
integrated database retrieval system
