Enhydra lutris kenyoni (northern sea otter): 111144322
Help
Entry
111144322 CDS
T05871
Definition
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase isoform X1
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk01521
EGFR tyrosine kinase inhibitor resistance
elk01522
Endocrine resistance
elk04010
MAPK signaling pathway
elk04012
ErbB signaling pathway
elk04014
Ras signaling pathway
elk04015
Rap1 signaling pathway
elk04022
cGMP-PKG signaling pathway
elk04024
cAMP signaling pathway
elk04062
Chemokine signaling pathway
elk04068
FoxO signaling pathway
elk04071
Sphingolipid signaling pathway
elk04072
Phospholipase D signaling pathway
elk04140
Autophagy - animal
elk04150
mTOR signaling pathway
elk04151
PI3K-Akt signaling pathway
elk04210
Apoptosis
elk04218
Cellular senescence
elk04270
Vascular smooth muscle contraction
elk04360
Axon guidance
elk04370
VEGF signaling pathway
elk04371
Apelin signaling pathway
elk04510
Focal adhesion
elk04540
Gap junction
elk04550
Signaling pathways regulating pluripotency of stem cells
elk04613
Neutrophil extracellular trap formation
elk04625
C-type lectin receptor signaling pathway
elk04630
JAK-STAT signaling pathway
elk04650
Natural killer cell mediated cytotoxicity
elk04660
T cell receptor signaling pathway
elk04662
B cell receptor signaling pathway
elk04664
Fc epsilon RI signaling pathway
elk04666
Fc gamma R-mediated phagocytosis
elk04720
Long-term potentiation
elk04722
Neurotrophin signaling pathway
elk04726
Serotonergic synapse
elk04730
Long-term depression
elk04810
Regulation of actin cytoskeleton
elk04910
Insulin signaling pathway
elk04912
GnRH signaling pathway
elk04914
Progesterone-mediated oocyte maturation
elk04915
Estrogen signaling pathway
elk04916
Melanogenesis
elk04917
Prolactin signaling pathway
elk04919
Thyroid hormone signaling pathway
elk04921
Oxytocin signaling pathway
elk04926
Relaxin signaling pathway
elk04928
Parathyroid hormone synthesis, secretion and action
elk04929
GnRH secretion
elk04935
Growth hormone synthesis, secretion and action
elk05010
Alzheimer disease
elk05022
Pathways of neurodegeneration - multiple diseases
elk05034
Alcoholism
elk05132
Salmonella infection
elk05152
Tuberculosis
elk05160
Hepatitis C
elk05161
Hepatitis B
elk05163
Human cytomegalovirus infection
elk05164
Influenza A
elk05165
Human papillomavirus infection
elk05167
Kaposi sarcoma-associated herpesvirus infection
elk05170
Human immunodeficiency virus 1 infection
elk05200
Pathways in cancer
elk05205
Proteoglycans in cancer
elk05206
MicroRNAs in cancer
elk05210
Colorectal cancer
elk05211
Renal cell carcinoma
elk05212
Pancreatic cancer
elk05213
Endometrial cancer
elk05214
Glioma
elk05215
Prostate cancer
elk05218
Melanoma
elk05219
Bladder cancer
elk05220
Chronic myeloid leukemia
elk05221
Acute myeloid leukemia
elk05223
Non-small cell lung cancer
elk05224
Breast cancer
elk05225
Hepatocellular carcinoma
elk05226
Gastric cancer
elk05230
Central carbon metabolism in cancer
elk05231
Choline metabolism in cancer
elk05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111144322
04012 ErbB signaling pathway
111144322
04014 Ras signaling pathway
111144322
04015 Rap1 signaling pathway
111144322
04370 VEGF signaling pathway
111144322
04371 Apelin signaling pathway
111144322
04630 JAK-STAT signaling pathway
111144322
04068 FoxO signaling pathway
111144322
04072 Phospholipase D signaling pathway
111144322
04071 Sphingolipid signaling pathway
111144322
04024 cAMP signaling pathway
111144322
04022 cGMP-PKG signaling pathway
111144322
04151 PI3K-Akt signaling pathway
111144322
04150 mTOR signaling pathway
111144322
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
111144322
09143 Cell growth and death
04210 Apoptosis
111144322
04218 Cellular senescence
111144322
09144 Cellular community - eukaryotes
04510 Focal adhesion
111144322
04540 Gap junction
111144322
04550 Signaling pathways regulating pluripotency of stem cells
111144322
09142 Cell motility
04810 Regulation of actin cytoskeleton
111144322
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
111144322
04625 C-type lectin receptor signaling pathway
111144322
04650 Natural killer cell mediated cytotoxicity
111144322
04660 T cell receptor signaling pathway
111144322
04662 B cell receptor signaling pathway
111144322
04664 Fc epsilon RI signaling pathway
111144322
04666 Fc gamma R-mediated phagocytosis
111144322
04062 Chemokine signaling pathway
111144322
09152 Endocrine system
04910 Insulin signaling pathway
111144322
04929 GnRH secretion
111144322
04912 GnRH signaling pathway
111144322
04915 Estrogen signaling pathway
111144322
04914 Progesterone-mediated oocyte maturation
111144322
04917 Prolactin signaling pathway
111144322
04921 Oxytocin signaling pathway
111144322
04926 Relaxin signaling pathway
111144322
04935 Growth hormone synthesis, secretion and action
111144322
04919 Thyroid hormone signaling pathway
111144322
04928 Parathyroid hormone synthesis, secretion and action
111144322
04916 Melanogenesis
111144322
09153 Circulatory system
04270 Vascular smooth muscle contraction
111144322
09156 Nervous system
04726 Serotonergic synapse
111144322
04720 Long-term potentiation
111144322
04730 Long-term depression
111144322
04722 Neurotrophin signaling pathway
111144322
09158 Development and regeneration
04360 Axon guidance
111144322
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111144322
05206 MicroRNAs in cancer
111144322
05205 Proteoglycans in cancer
111144322
05230 Central carbon metabolism in cancer
111144322
05231 Choline metabolism in cancer
111144322
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
111144322
09162 Cancer: specific types
05210 Colorectal cancer
111144322
05212 Pancreatic cancer
111144322
05225 Hepatocellular carcinoma
111144322
05226 Gastric cancer
111144322
05214 Glioma
111144322
05221 Acute myeloid leukemia
111144322
05220 Chronic myeloid leukemia
111144322
05218 Melanoma
111144322
05211 Renal cell carcinoma
111144322
05219 Bladder cancer
111144322
05215 Prostate cancer
111144322
05213 Endometrial cancer
111144322
05224 Breast cancer
111144322
05223 Non-small cell lung cancer
111144322
09164 Neurodegenerative disease
05010 Alzheimer disease
111144322
05022 Pathways of neurodegeneration - multiple diseases
111144322
09165 Substance dependence
05034 Alcoholism
111144322
09171 Infectious disease: bacterial
05132 Salmonella infection
111144322
05152 Tuberculosis
111144322
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
111144322
05161 Hepatitis B
111144322
05160 Hepatitis C
111144322
05164 Influenza A
111144322
05163 Human cytomegalovirus infection
111144322
05167 Kaposi sarcoma-associated herpesvirus infection
111144322
05165 Human papillomavirus infection
111144322
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111144322
01522 Endocrine resistance
111144322
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
elk01001
]
111144322
Enzymes [BR:
elk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
111144322
Protein kinases [BR:
elk01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
111144322
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
111144322
NCBI-ProteinID:
XP_022354272
UniProt:
A0A2Y9J054
LinkDB
All DBs
Position
Unknown
AA seq
668 aa
AA seq
DB search
MEHIQGAWKTISNGFGFKDTVFDGPSCISPTIVQPFGFQRRASDDGKLTDSSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTF
NSSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIENNSLNASPRAWSRRFCLRGRDA
IRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPGSGTQEKNKIRPRGQRDSSY
YWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKT
RHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLH
AKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQ
DNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKA
MKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLT
TSPRLPVF
NT seq
2007 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggggcctggaagacgatcagcaacggttttggattcaaagacaca
gtgtttgacggccccagctgcatctcgcctacaatagttcagccatttggctttcagcgt
cgggcgtcagatgatggcaaacttacggactcgtctaagacaagcaacactatccgtgtt
ttcttgccaaacaagcaaagaacagtggtcaatgtgcgaaatggaatgagcttgcacgat
tgccttatgaaggcactcaaggtgaggggcctacagccggagtgctgtgctgtgttcaga
cttctccatgaacataaaggtaaaaaggcacgtttagattggaatactgatgctgcctcg
ttgattggagaagaacttcaagtagatttcctggatcacgttcccctcacaacacacaac
tttgcacggaagacctttctgaagcttgcgttctgtgacatctgtcagaagttcctgcta
aatggatttcgttgtcagacttgtggctacaaatttcatgagcactgtagcaccaaagtt
cctactatgtgtgtggattggagtaatatcagacagctcttattgtttccaaattctact
attggtgatagtggggtcccagcactgccttctttgactatgcgtcggatgcgagagtct
gtttcccggatgcctgttagttcccagcacagatattccacaccccatgccttcacattc
aactcctccagcccttcctctgaaggttccctttcccagaggcagaggtccacatccaca
cctaatgtccacatggtcagcaccaccctgcctgtggacagcaggatgattgagaataac
agcctgaatgcttctcccagggcgtggtccagacgattttgtttgaggggaagagatgca
attcgaagccacagtgaatcagcctcaccttcagccttgtccagcagccctaacaatctg
agcccaacaggctggtcacagcccaaaacccctgtgccagcacagagagagcgggcacca
ggatctgggacccaggagaaaaacaaaattaggcctcgtggacagagagattcaagctat
tactgggaaatagaagccagcgaagtgatgctctccactcggattgggtcaggctccttt
ggaacggtgtataagggcaagtggcacggagatgttgcagtaaaaatcctaaaggttgtc
gaccccacaccagagcagttccaggccttcaggaacgaggtggctgtcctccgcaaaaca
cggcatgtgaacatcctgctcttcatggggtacatgacaaaggacaacctggcgattgtg
acccagtggtgtgaaggcagcagcctctacaaacacctgcatgtccaggagactaaattc
cagatgttccagttgattgacatcgcccgccagactgctcagggaatggactatttgcat
gcaaagaacatcatccatagagacatgaaatccaacaatatatttctccatgaaggcctg
acggtgaaaattggagattttggtttggcaacagtaaagtcgcgctggagtggttctcag
caagttgaacaacccactggctctgtcctgtggatggcgcctgaggtgatccgaatgcag
gataacaacccgttcagcttccagtctgatgtctactcctacggcattgtgctctatgag
ctcatgacaggggagcttccttactcccacatcaataaccgtgatcagatcatcttcatg
gtgggccgagggtatgcctccccagacctcagtaagctatataagaactgccccaaagca
atgaagaggcttgtagccgactgtgtgaagaaggttaaggaagagaggcctctttttccc
cagatactgtcttccatcgagctgctccaacattctctgccgaaaatcaaccggagcgct
tctgagccatccctgcaccgggcggcccacactgaggatatcaacgcctgcacactgact
acgtcccctagactgcctgtcttctag
Enhydra lutris kenyoni (northern sea otter): 111150582
Help
Entry
111150582 CDS
T05871
Definition
(RefSeq) serine/threonine-protein kinase A-Raf isoform X1
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk01521
EGFR tyrosine kinase inhibitor resistance
elk01522
Endocrine resistance
elk04010
MAPK signaling pathway
elk04012
ErbB signaling pathway
elk04068
FoxO signaling pathway
elk04270
Vascular smooth muscle contraction
elk04650
Natural killer cell mediated cytotoxicity
elk04720
Long-term potentiation
elk04726
Serotonergic synapse
elk04730
Long-term depression
elk04810
Regulation of actin cytoskeleton
elk04910
Insulin signaling pathway
elk04914
Progesterone-mediated oocyte maturation
elk04928
Parathyroid hormone synthesis, secretion and action
elk05010
Alzheimer disease
elk05022
Pathways of neurodegeneration - multiple diseases
elk05034
Alcoholism
elk05160
Hepatitis C
elk05161
Hepatitis B
elk05200
Pathways in cancer
elk05205
Proteoglycans in cancer
elk05210
Colorectal cancer
elk05211
Renal cell carcinoma
elk05212
Pancreatic cancer
elk05213
Endometrial cancer
elk05214
Glioma
elk05215
Prostate cancer
elk05218
Melanoma
elk05219
Bladder cancer
elk05220
Chronic myeloid leukemia
elk05221
Acute myeloid leukemia
elk05223
Non-small cell lung cancer
elk05224
Breast cancer
elk05225
Hepatocellular carcinoma
elk05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111150582
04012 ErbB signaling pathway
111150582
04068 FoxO signaling pathway
111150582
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
111150582
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
111150582
09152 Endocrine system
04910 Insulin signaling pathway
111150582
04914 Progesterone-mediated oocyte maturation
111150582
04928 Parathyroid hormone synthesis, secretion and action
111150582
09153 Circulatory system
04270 Vascular smooth muscle contraction
111150582
09156 Nervous system
04726 Serotonergic synapse
111150582
04720 Long-term potentiation
111150582
04730 Long-term depression
111150582
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111150582
05205 Proteoglycans in cancer
111150582
09162 Cancer: specific types
05210 Colorectal cancer
111150582
05212 Pancreatic cancer
111150582
05225 Hepatocellular carcinoma
111150582
05226 Gastric cancer
111150582
05214 Glioma
111150582
05221 Acute myeloid leukemia
111150582
05220 Chronic myeloid leukemia
111150582
05218 Melanoma
111150582
05211 Renal cell carcinoma
111150582
05219 Bladder cancer
111150582
05215 Prostate cancer
111150582
05213 Endometrial cancer
111150582
05224 Breast cancer
111150582
05223 Non-small cell lung cancer
111150582
09164 Neurodegenerative disease
05010 Alzheimer disease
111150582
05022 Pathways of neurodegeneration - multiple diseases
111150582
09165 Substance dependence
05034 Alcoholism
111150582
09172 Infectious disease: viral
05161 Hepatitis B
111150582
05160 Hepatitis C
111150582
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111150582
01522 Endocrine resistance
111150582
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
elk01001
]
111150582
Enzymes [BR:
elk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
111150582
Protein kinases [BR:
elk01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
111150582
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
TUG-UBL1
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
111150582
NCBI-ProteinID:
XP_022363789
UniProt:
A0A2Y9JWA3
LinkDB
All DBs
Position
Unknown
AA seq
628 aa
AA seq
DB search
MTGAPWHLLSPTSTRLDKVLGSMEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDG
MSVYDSLDKALKVRGLNQDCCVVYRLIEGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTM
HNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNCRQFYHSV
QDLSGGSRQHEVPSNRPLNEPLTPQGPSSCTPHRDPEHFPFPAPANAPLQRIRSTSTPNV
HMVSTTAATDSSLIQLTTRSFGTDAAGSRGGGDGAPRGSPSPASVPSGRKSPHSKSPSEQ
RERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVL
KVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVAD
TRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNSIFLHEGLTVKIGDFGLATVKTRWS
GAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQI
IFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIE
RSASEPSLHRTQADELPACLLSAARLVP
NT seq
1887 nt
NT seq
+upstream
nt +downstream
nt
atgacaggagccccatggcacctgctcagccccacctcaacccgtcttgacaaagtccta
ggctccatggagccaccacggggcccccctgccaacggggccgagccgtcccgggcagtg
ggcactgtcaaagtatatttgcccaacaagcaacgcacggtggtgactgtccgggatggc
atgagtgtctacgactctctagacaaggccctcaaggtacggggtctcaatcaggattgc
tgtgtggtctaccggctcatcgaggggcgaaagacagtcaccgcctgggacacggccatt
gcccccctggatggagaggagctcattgtagaggtcctcgaagatgttccactgaccatg
cacaattttgtacggaagacgttcttcagcctggcattctgtgacttctgccttaaattt
ctgttccacggcttccgctgccaaacctgtggctacaagttccaccagcattgttcctct
aaagtccccacagtctgtgttgacatgagcaccaactgccgacagttctaccacagtgtc
caggatttgtccggaggctccagacagcacgaggttccctcgaaccgtcccctgaatgag
ccactaacccctcagggtcccagctcctgcaccccacaccgagaccccgagcactttccc
ttccccgcgccggccaacgccccgctccagcgcatccgctccacatccactcccaacgtc
cacatggtcagcaccacagccgccacggactccagcctcatccagctcactacccggagt
ttcggcaccgatgctgctggtagtagaggtggtggtgatggagccccccgggggagcccc
agcccagccagcgtgccctcggggaggaagtccccccattccaagtccccgtcggagcag
cgggagcggaagtccttggccgatgacaagaagaaagtgaagaatctggggtaccgggac
tcgggctattactgggaggtgccgcccagcgaggtgcagctgctgaagaggatcgggaca
ggctcgttcggcactgtgtttcgtgggcggtggcatggcgatgtggccgtgaaggtgctc
aaggtggcccaacccacagctgagcaggcccaggccttcaagaacgagatgcaggtgctc
aggaagacccgtcacgtcaacatcttgctgttcatgggcttcatgacgcggccgggattt
gccatcatcacgcagtggtgtgagggctccagcctctaccaccacctgcacgtggccgac
actcgcttcgacatggtccagctcatcgacgtggcccggcagactgcccagggcatggac
tacctccacgccaagaacatcattcatcgagatctcaagtctaacagtatcttcctacat
gaggggctcacagtgaagattggtgactttggcctggccacagtgaagacacggtggagt
ggggcccagcccttggagcagccctcgggctccgtgctatggatggcggctgaggtgatc
cgtatgcaggacccgaacccctacagcttccagtcggatgtctacgcctatggggttgtg
ctctatgagctcatgaccggctcgctgccttacagccacattggcagccgtgaccagatt
atctttatggtgggccgtggctatctgtccccggacctcagcaaaatctccagcaactgc
cccaaggccatgcggcgcctgctgtctgactgcctcaagttccagcgggaggaacgtccc
ctcttcccccagatcctggccacgattgagctgctgcagcggtcactccccaagattgag
cggagtgcctctgaaccctccttgcaccgcacccaggccgatgagttgcctgcctgcctc
ctcagcgcggcccgcctcgtgccttag
Enhydra lutris kenyoni (northern sea otter): 111151941
Help
Entry
111151941 CDS
T05871
Definition
(RefSeq) serine/threonine-protein kinase B-raf isoform X1
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk01521
EGFR tyrosine kinase inhibitor resistance
elk01522
Endocrine resistance
elk04010
MAPK signaling pathway
elk04012
ErbB signaling pathway
elk04015
Rap1 signaling pathway
elk04024
cAMP signaling pathway
elk04062
Chemokine signaling pathway
elk04068
FoxO signaling pathway
elk04150
mTOR signaling pathway
elk04270
Vascular smooth muscle contraction
elk04510
Focal adhesion
elk04650
Natural killer cell mediated cytotoxicity
elk04720
Long-term potentiation
elk04722
Neurotrophin signaling pathway
elk04726
Serotonergic synapse
elk04730
Long-term depression
elk04810
Regulation of actin cytoskeleton
elk04910
Insulin signaling pathway
elk04914
Progesterone-mediated oocyte maturation
elk04928
Parathyroid hormone synthesis, secretion and action
elk04934
Cushing syndrome
elk05010
Alzheimer disease
elk05022
Pathways of neurodegeneration - multiple diseases
elk05034
Alcoholism
elk05160
Hepatitis C
elk05161
Hepatitis B
elk05200
Pathways in cancer
elk05205
Proteoglycans in cancer
elk05210
Colorectal cancer
elk05211
Renal cell carcinoma
elk05212
Pancreatic cancer
elk05213
Endometrial cancer
elk05214
Glioma
elk05215
Prostate cancer
elk05216
Thyroid cancer
elk05218
Melanoma
elk05219
Bladder cancer
elk05220
Chronic myeloid leukemia
elk05221
Acute myeloid leukemia
elk05223
Non-small cell lung cancer
elk05224
Breast cancer
elk05225
Hepatocellular carcinoma
elk05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111151941
04012 ErbB signaling pathway
111151941
04015 Rap1 signaling pathway
111151941
04068 FoxO signaling pathway
111151941
04024 cAMP signaling pathway
111151941
04150 mTOR signaling pathway
111151941
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
111151941
09142 Cell motility
04810 Regulation of actin cytoskeleton
111151941
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
111151941
04062 Chemokine signaling pathway
111151941
09152 Endocrine system
04910 Insulin signaling pathway
111151941
04914 Progesterone-mediated oocyte maturation
111151941
04928 Parathyroid hormone synthesis, secretion and action
111151941
09153 Circulatory system
04270 Vascular smooth muscle contraction
111151941
09156 Nervous system
04726 Serotonergic synapse
111151941
04720 Long-term potentiation
111151941
04730 Long-term depression
111151941
04722 Neurotrophin signaling pathway
111151941
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111151941
05205 Proteoglycans in cancer
111151941
09162 Cancer: specific types
05210 Colorectal cancer
111151941
05212 Pancreatic cancer
111151941
05225 Hepatocellular carcinoma
111151941
05226 Gastric cancer
111151941
05214 Glioma
111151941
05216 Thyroid cancer
111151941
05221 Acute myeloid leukemia
111151941
05220 Chronic myeloid leukemia
111151941
05218 Melanoma
111151941
05211 Renal cell carcinoma
111151941
05219 Bladder cancer
111151941
05215 Prostate cancer
111151941
05213 Endometrial cancer
111151941
05224 Breast cancer
111151941
05223 Non-small cell lung cancer
111151941
09164 Neurodegenerative disease
05010 Alzheimer disease
111151941
05022 Pathways of neurodegeneration - multiple diseases
111151941
09165 Substance dependence
05034 Alcoholism
111151941
09167 Endocrine and metabolic disease
04934 Cushing syndrome
111151941
09172 Infectious disease: viral
05161 Hepatitis B
111151941
05160 Hepatitis C
111151941
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111151941
01522 Endocrine resistance
111151941
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
elk01001
]
111151941
Enzymes [BR:
elk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
111151941
Protein kinases [BR:
elk01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
111151941
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
C1_2
Pkinase_fungal
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
111151941
NCBI-ProteinID:
XP_022365887
UniProt:
A0A2Y9JXN1
LinkDB
All DBs
Position
Unknown
AA seq
817 aa
AA seq
DB search
MAALSGGGGGSGAEQGQALFNGDMEPEAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHI
EALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASTDTVT
SSSSSSLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSL
KKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKT
FFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIP
QEEASIAETALSSGSSPSAPPSDSTGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRD
RSSSAPNVHINTIEPVNIDDLIRDQGFRSDGGSTTGLSATPPASLPGSLTNVKALQKSPG
PQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVA
VKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHL
HIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVK
SRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINN
RDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL
PKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYDTEFSMHKLVWNRMEFPIHQK
REECFRNQNSLLPVFLLQHKYHVHTSLPTPRKEEERA
NT seq
2454 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagcggcggcggcggcggcagcggcgcggagcagggccaggctctgttc
aacggggatatggagcccgaggccggcgccggcgccgcggcctcttcggctgcggaccct
gccattcccgaggaggtgtggaatatcaaacaaatgattaagttgacacaggaacatata
gaagccctattggacaaatttggtggggagcataatccaccatcaatatatctggaggcc
tatgaagaatacaccagcaagctagatgccctccaacagcgagaacaacagttattggaa
tccctggggaatggaactgatttttctgtttctagctctgcatcaacagacaccgttaca
tcttcttcctcctctagcctttcagtgctaccttcatctctttcagtttttcaaaatccc
acagatgtatcacggagcaatccaaagtcaccacaaaaacctatcgttagagtcttcctg
cccaataaacagaggacagtggtacctgcaagatgtggagttacagtccgagacagtcta
aagaaagctctgatgatgagaggtctaatcccagagtgctgtgctgtttacagaattcag
gatggagagaagaaaccgattggctgggacactgatatttcctggctcactggagaggaa
ctacatgtagaagtgttggaaaatgtcccgcttaccacacacaactttgtacggaaaact
tttttcaccttagcattttgtgacttttgtcgaaagctgcttttccagggttttcgctgt
caaacatgtggttataaatttcaccagcgttgtagtacagaggtcccactgatgtgtgtt
aattatgaccaacttgatttgctgtttgtctccaagttctttgaacaccacccaatacca
caggaggaggcctccatagcagagactgccctttcgtccggatcatccccttctgctccc
ccctccgattctactgggccccaaatcctcaccagtccgtctccttcaaaatccattcca
attccacagcctttccgaccagcagatgaagatcatcgaaatcaatttggacaacgagac
cggtcctcatcagctccaaatgtgcatataaacacaatagaacctgtcaatattgatgac
ttgattagagaccaagggtttcgtagtgacggaggatcaaccactggtttgtctgccacc
ccccctgcctcattgcctggctcactcactaatgtgaaagcattacagaaatctccagga
cctcagcgggaaaggaaatcatcttcatcctcagaagataggaatcgaatgaaaacactt
ggtagacgggattcaagtgatgattgggagattcctgatgggcagatcacagtgggacag
agaatcggatccgggtcatttgggacagtctacaagggaaagtggcatggtgatgtggca
gtgaaaatgttgaatgtgacagcgcccacacctcagcagttacaggccttcaaaaatgaa
gtaggagtactcaggaaaactcgacatgtgaacatcctacttttcatgggctattcaaca
aagccccaactagctattgttacccagtggtgtgagggctccagcttatatcaccatctc
cacatcatcgagaccaaatttgagatgatcaagcttatagatattgcacggcagactgcg
cagggcatggattacttacacgccaagtcaatcatccacagagacctcaagagtaataat
atttttcttcatgaagacctcacagtaaaaataggtgattttggtctagccacagtgaaa
tctcgatggagtgggtcccatcagtttgaacagttgtctggatccattttgtggatggcg
ccagaagtgatccgaatgcaagataaaaacccatatagctttcagtcagatgtctatgca
tttgggattgttctatatgaattgatgaccggacagttaccttattcaaacatcaacaac
agggaccagataatttttatggttggacgaggatatctttctccagatctcagtaaggta
cggagtaactgtccaaaagccatgaagagattgatggcagagtgcctaaaaaagaaaaga
gatgagaggccactctttccccaaattctcgcctctattgagctgctggcccgctcattg
ccaaaaattcaccgcagtgcatcagaaccctccttgaatcgggctggcttccaaacagag
gattttagtctatatgcttgtgcttctccaaaaacacccatccaggcagggggatatgat
acagaattttcaatgcataagctggtgtggaacagaatggaatttcccatccaccaaaag
agggaagaatgttttaggaaccagaattctctgctgccagtgtttcttcttcaacacaaa
taccacgtgcatacaagtctgcccactcccaggaaggaagaggagagagcctga
DBGET
integrated database retrieval system
