KEGG   Enhydra lutris kenyoni (northern sea otter): 111151241
Entry
111151241         CDS       T05871                                 

Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
elk  Enhydra lutris kenyoni (northern sea otter)
Pathway
elk01521  EGFR tyrosine kinase inhibitor resistance
elk04062  Chemokine signaling pathway
elk04066  HIF-1 signaling pathway
elk04068  FoxO signaling pathway
elk04217  Necroptosis
elk04550  Signaling pathways regulating pluripotency of stem cells
elk04630  JAK-STAT signaling pathway
elk04659  Th17 cell differentiation
elk04917  Prolactin signaling pathway
elk04920  Adipocytokine signaling pathway
elk04931  Insulin resistance
elk04933  AGE-RAGE signaling pathway in diabetic complications
elk04935  Growth hormone synthesis, secretion and action
elk05145  Toxoplasmosis
elk05160  Hepatitis C
elk05161  Hepatitis B
elk05162  Measles
elk05163  Human cytomegalovirus infection
elk05167  Kaposi sarcoma-associated herpesvirus infection
elk05169  Epstein-Barr virus infection
elk05200  Pathways in cancer
elk05203  Viral carcinogenesis
elk05205  Proteoglycans in cancer
elk05206  MicroRNAs in cancer
elk05212  Pancreatic cancer
elk05221  Acute myeloid leukemia
elk05223  Non-small cell lung cancer
elk05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
elk05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:elk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    111151241
   04066 HIF-1 signaling pathway
    111151241
   04068 FoxO signaling pathway
    111151241
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    111151241
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    111151241
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    111151241
   04062 Chemokine signaling pathway
    111151241
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    111151241
   04917 Prolactin signaling pathway
    111151241
   04935 Growth hormone synthesis, secretion and action
    111151241
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111151241
   05206 MicroRNAs in cancer
    111151241
   05205 Proteoglycans in cancer
    111151241
   05203 Viral carcinogenesis
    111151241
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    111151241
  09162 Cancer: specific types
   05212 Pancreatic cancer
    111151241
   05221 Acute myeloid leukemia
    111151241
   05223 Non-small cell lung cancer
    111151241
  09163 Immune disease
   05321 Inflammatory bowel disease
    111151241
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    111151241
   04933 AGE-RAGE signaling pathway in diabetic complications
    111151241
  09172 Infectious disease: viral
   05162 Measles
    111151241
   05161 Hepatitis B
    111151241
   05160 Hepatitis C
    111151241
   05163 Human cytomegalovirus infection
    111151241
   05167 Kaposi sarcoma-associated herpesvirus infection
    111151241
   05169 Epstein-Barr virus infection
    111151241
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    111151241
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    111151241
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:elk03000]
    111151241
Transcription factors [BR:elk03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    111151241
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 Baculo_PEP_C DUF4795 Syntaxin-6_N
Other DBs
NCBI-GeneID: 111151241
NCBI-ProteinID: XP_022364790
UniProt: A0A2Y9K559
LinkDB
Position
Unknown
AA seq 802 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAAWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRNIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKVGARPLETVVVPHVGPWAPLSHLTEQPCYFQQNVNFFTKPPIGTWDQVAEVL
SWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNI
IDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDI
SGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCR
PESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSA
GGQFESLTFDMELTSECATSPM
NT seq 2409 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctacagcagctcgacacgcggtacctggagcagcttcatcag
ctgtacagcgacagcttcccgatggagctgcggcagtttctggctgcttggatcgagagt
caggattgggcatatgcggccagcaaggaatcacatgcaactttggtgtttcataatctc
ctgggtgagattgaccagcaatacagccgtttcctgcaggagtcaaatgttctctatcag
cacaatctgcggagaatcaagcagttccttcagagcagatatctggagaagccaatggag
attgcccgaatcgtggcccggtgcctgtgggaagagtcccgcctgctccagactgcggcc
actgcagcccagcaagggggccaggccaaccaccccacagccgccgtggtgacagagaag
cagcagatgctagagcagcacctacaagatgttcggaagcgagtacaggatctagaacag
aaaatgaaagtggtcgagaatctccaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaggacctgaatggaaacaaccagtcagtgaccaggcagaagatg
cagcagctggagcagatgctcacggcgctggaccagatgcggcggaacatcgtgagtgag
ttggcggggctgttgtccgcgatggagtatgtgcagaaaactctcacggacgaagagctg
gctgactggaagaggcggcaacagattgcgtgcatcggaggccctcccaacatctgctta
gatcgcctcgaaaactggataacctcattagcggaatctcaacttcagacccgccaacaa
attaagaaactagaggagttgcagcagaaagtgtcctacaagggggatcccatcgtacag
caccggccaatgctggaggagaggattgtagagctgtttagaaacttaatgaaaagtgcc
tttgtggtcgagcggcagccctgtatgcccatgcaccctgaccggccattggtcatcaag
actggagtccagttcactaccaaagtcagattgctggtcaagttccctgagttaaattat
cagcttaaaattaaagtgtgcattgacaaagactccggggatgttgcagctctcagaggg
tcccggaagtttaacattctgggcacaaacacaaaagtgatgaacatggaagagtccaac
aatggcagcctgtctgcagaattcaaacacctgaccctgagagagcaaagatgtggtaac
gggggccgagccaattgtgacgcctccctgattgtcaccgaggagctgcacctgatcaca
tttgagactgaggtgtatcaccaaggcctcaagattgaccttgagacccattccttgcca
gttgtggtgatctccaacatctgtcagatgccaaacgcctgggcatcaatcctgtggtat
aacatgctgaccaacaaccccaaggtaggcgcccgtcctctggaaaccgttgttgtccct
catgtgggtccttgggcaccgctgtctcatctcactgagcaaccgtgttattttcaacag
aacgtgaacttcttcaccaagcccccgattggcacctgggatcaagtggccgaggtgctg
agctggcagttctcctccaccacaaagcgagggctgagcatcgagcagttgacgacattg
gctgagaaactcttaggacccggtgtgaactattcagggtgtcagattacgtgggctaaa
ttttgcaaagaaaacatggctggcaaaggcttctccttctgggtttggctggacaatatc
attgaccttgtgaaaaagtacatcctggctctttggaatgaagggtacataatgggtttt
atcagtaaggagcgggagcgggccatcttgagcaccaagcccccaggcaccttcctgcta
cggttcagtgaaagcagcaaagaaggaggtgtcaccttcacttgggtagagaaggacatc
agcggtaagacccagatccagtcagtggaaccatatactaagcagcagctgaacaacatg
tcatttgctgaaatcatcatgggctataagatcatggacgctaccaatatcctggtgtct
ccgctggtctatctctaccccgacattccgaaggaggaggcgtttggaaagtactgtcga
ccagagagccaggagcatcccgaagctgacccaggtagtgctgctccatacctgaagacc
aagtttatctgtgtgacaccaacgacgtgcagcaataccattgacctgccgatgtccccc
cgcactttagattcattgatgcagtttggaaataatggtgaaggtgctgagccctcagca
ggagggcagttcgagtccctcacgttcgacatggagttgacctcggagtgcgctacctcc
ccgatgtga

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