Enhydra lutris kenyoni (northern sea otter): 111151268
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Entry
111151268 CDS
T05871
Definition
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk01521
EGFR tyrosine kinase inhibitor resistance
elk01522
Endocrine resistance
elk01524
Platinum drug resistance
elk04010
MAPK signaling pathway
elk04012
ErbB signaling pathway
elk04020
Calcium signaling pathway
elk04066
HIF-1 signaling pathway
elk04151
PI3K-Akt signaling pathway
elk04510
Focal adhesion
elk04520
Adherens junction
elk04530
Tight junction
elk05200
Pathways in cancer
elk05205
Proteoglycans in cancer
elk05206
MicroRNAs in cancer
elk05212
Pancreatic cancer
elk05213
Endometrial cancer
elk05215
Prostate cancer
elk05219
Bladder cancer
elk05223
Non-small cell lung cancer
elk05224
Breast cancer
elk05226
Gastric cancer
elk05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111151268
04012 ErbB signaling pathway
111151268
04066 HIF-1 signaling pathway
111151268
04020 Calcium signaling pathway
111151268
04151 PI3K-Akt signaling pathway
111151268
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
111151268
04520 Adherens junction
111151268
04530 Tight junction
111151268
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111151268
05206 MicroRNAs in cancer
111151268
05205 Proteoglycans in cancer
111151268
05230 Central carbon metabolism in cancer
111151268
09162 Cancer: specific types
05212 Pancreatic cancer
111151268
05226 Gastric cancer
111151268
05219 Bladder cancer
111151268
05215 Prostate cancer
111151268
05213 Endometrial cancer
111151268
05224 Breast cancer
111151268
05223 Non-small cell lung cancer
111151268
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111151268
01524 Platinum drug resistance
111151268
01522 Endocrine resistance
111151268
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
elk01001
]
111151268
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
elk04147
]
111151268
04090 CD molecules [BR:
elk04090
]
111151268
Enzymes [BR:
elk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
111151268
Protein kinases [BR:
elk01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
111151268
Exosome [BR:
elk04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
111151268
CD molecules [BR:
elk04090
]
Proteins
111151268
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Kinase-like
CBP_BcsF
Motif
Other DBs
NCBI-GeneID:
111151268
NCBI-ProteinID:
XP_022364850
UniProt:
A0A2Y9K5K2
LinkDB
All DBs
Position
Unknown
AA seq
1268 aa
AA seq
DB search
MELAAWCRWGLLLALLPSGVVGTQVCTGTDMKLRLPASPETHLDMLRHLYQACQVVQGNL
ELTYLPANASLSFLQDIQEVQGYVLIAHSQVRQVPLQRLRIVRGTQLFEDHYALAVLDNG
DPPEGGPSVAGAAPEGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LTLIDTNRSRACQPCSPACKDPHCWGASSGDCQSLTRTVCAGGCARCKGPKPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLP
DLSVFQNLRVIRGRVLHDGAYSLTLRGLGISSLGLRSLRELGSGLALIHRNAHLCFIHTV
PWDQLFRNPHQALLHSANRPEAECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRYCLPCHSECRPQNGSVTCFGSEADQCVACAHYKDTPFCVSRC
PSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDERGCPAEQRASPVTSIIAAVVG
ILLAVLVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGPAHRRHRSSSTRVSALGHTVSGGGELTMGLEPSEEEPPK
SPRAPSEGAGSDVFDGDLGMGAAKGLQSLPPQDPSPLQRYSEDPTAPLAPETDGYVAPLT
CSPQPEYVNQPEVWPQPPSPLEGPLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDVFAF
GSAVENPEYLVPQGRAAPQPHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPE
YLGLDVPV
NT seq
3807 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctgctcgccctcctgccctccggagtc
gtgggcacccaagtgtgcaccggcacagacatgaagctgcggctcccagccagtcccgag
acccacctggatatgctccgccacctctaccaggcctgtcaagtggtgcagggtaacctg
gagctcacctacctgcctgccaatgctagcctgtccttcctgcaggatatccaggaggtg
cagggctacgtgctcatcgctcacagccaagtgagacaggtcccgctgcagaggctccga
atcgtgcggggcacccagctctttgaggaccactatgccctggccgtgctggacaatgga
gatccgcccgaggggggcccctctgtggcaggggctgccccagaagggctgcgggagctg
cagcttcgaagcctcacagagatcctgaagggcggggtcttgattcagcggaacccacag
ctctgccaccaggacacgatcctgtggaaggacatcttccacaagaacaaccagctggcc
ctcacgctgatagacaccaaccgctctcgggcctgccagccctgttctccagcttgtaaa
gacccccactgctggggagcaagttccggggactgtcagagcttgacgcgaaccgtctgt
gctggcggctgtgcccgatgcaagggcccgaaacccacggactgctgccacgagcagtgt
gcggctggctgcacgggccccaagcactcggactgcctggcctgccttcacttcaaccac
agtggcatctgtgagctgcactgtccagctctggtcacctacaacacagacaccttcgaa
tccatgcccaaccctgagggccggtacaccttcggagccagctgtgtgaccgcctgtccc
tacaattacctgtcaacggatgtgggatcctgcaccctggtctgtcccctgaacaaccaa
gaggtgaccgctgaggacggaacgcagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctatggcctgggcatggagcacctgcgggaggtgagggcggtcaccagcgccaac
atccaagagtttgctggctgcaagaagatctttgggagcctggcatttctgccagaaagc
tttgagggagacccagcctccaacactgcccccctccagcctgagcagctcagagtgttt
gaggctctggaggagatcacaggttacctgtacatctcagcatggccagacagcctgcct
gacctcagtgtcttccagaacctgcgagtcatccggggacgagttctgcatgacggcgcc
tactcactgaccctgcgagggctgggcatcagctcgctggggctgcgctcgctgcgggaa
ctgggtagtgggctggccctcatccaccgcaacgcccacctgtgcttcatacacacggtg
ccctgggaccagctcttccggaacccgcaccaggccctgctccatagcgccaaccggcca
gaggccgagtgtgtgggcgagggcctggcctgctacccgctgtgtgcccatgggcactgc
tggggtccggggcccacccagtgcgtcaactgcagccaattccttcggggccaggagtgc
gtggaggaatgccgagtactgcaggggctaccccgggagtatgtgaaggacaggtactgt
ctcccgtgccactccgagtgtcggccgcagaacggctcagtgacctgctttgggtcggaa
gctgaccagtgtgtggcctgcgcccactacaaggacactcccttctgcgtgtctcgctgc
cccagtggcgtgaaacctgacctctccttcatgcccatttggaagttcgccgatgaggag
ggcacgtgccagccgtgccccatcaactgcacccactcctgtgcggatctggacgagagg
ggctgccctgccgagcagagagccagccctgtgacgtccattattgcggctgtggtgggc
attctgctggccgtgcttgtggggctggtcctcggcatcctaatcaagcgaaggcggcag
aagatccgcaagtacacgatgcggaggctgctgcaggaaaccgagctggtggagccgctg
acgcctagcggagccatgcccaaccaggctcagatgcggatcctgaaagagacagaactg
aggaaggtgaaagtgcttggatccggagcctttggcaccgtctacaagggcatctggatc
cctgatggggaaaatgtgaagatcccagtggccattaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggacgaagcatatgtgatggctggcgtgggctcccca
tatgtgtcccgccttctgggcatctgcctgacatccacggtgcagctggtgacacagctt
atgccctatggctgcctcttagaccacgtccgagagcaccgtgggcgcctgggctcccag
gacctgctgaactggtgtgtgcagatcgctaaggggatgagctacttggaggacgttcgg
ctggtgcacagggacctggctgcccggaacgtgctggtcaagagtcctaaccatgtcaag
ataacagactttgggctggctcggttgctggacattgacgagaccgagtaccatgcagat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
caccagagtgacgtgtggagctatggtgtgactgtgtgggaactgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggaaaagggggaacgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
atagactctgaatgtcgaccacggttccgggagttggtggccgaattctcccgcatggcc
agggacccccagcgcttcgtggtcatccagaatgaagacttgggccccgccagtccactg
gacagcaccttctaccgctcgctgctggaagatgatgacatgggggacctggtggatgct
gaggagtacctggtgccccagcaggggttcttctgccccgaccctgccccaggtgctggg
ggcccggcccaccgcaggcaccgcagctcatccacgagggtcagtgcgctcggtcacacc
gtgagtggcggtggtgagctgacaatgggactggagccctccgaggaggagcccccaaag
tctccacgggcaccctcagagggggctggctctgacgtgtttgatggcgacttgggaatg
ggggcagccaaggggctgcagagtcttcccccacaggaccccagccctctacagcggtac
agcgaggaccctactgcacccctggccccagagactgatggctatgttgcccccctgacc
tgcagcccccagcctgaatacgtgaaccagccggaggtttggccgcagcccccctcgccc
ctggaaggccctctgcctccttctcgacctgccggtgccactctggaaaggcccaagact
ctgtcccccaagactctctcccctggcaagaatggggttgtcaaagacgtttttgccttt
gggagtgctgtggagaaccctgagtacttggtaccccagggcagggctgcccctcagccc
caccctcctccagccttcagtccagcctttgacaacctctattactgggaccaggaccca
tcagagcggggctctccacccagcacctttgaagggacccctacagcagagaatcctgag
tacctgggcctggatgtgccagtgtga
DBGET
integrated database retrieval system
