KEGG   Enhydra lutris kenyoni (northern sea otter): 111159390
Entry
111159390         CDS       T05871                                 

Definition
(RefSeq) hypoxia-inducible factor 1-alpha isoform X1
  KO
K08268  hypoxia-inducible factor 1 alpha
Organism
elk  Enhydra lutris kenyoni (northern sea otter)
Pathway
elk04066  HIF-1 signaling pathway
elk04137  Mitophagy - animal
elk04140  Autophagy - animal
elk04659  Th17 cell differentiation
elk04919  Thyroid hormone signaling pathway
elk05167  Kaposi sarcoma-associated herpesvirus infection
elk05200  Pathways in cancer
elk05205  Proteoglycans in cancer
elk05211  Renal cell carcinoma
elk05230  Central carbon metabolism in cancer
elk05231  Choline metabolism in cancer
elk05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:elk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    111159390
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    111159390
   04137 Mitophagy - animal
    111159390
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    111159390
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    111159390
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111159390
   05205 Proteoglycans in cancer
    111159390
   05230 Central carbon metabolism in cancer
    111159390
   05231 Choline metabolism in cancer
    111159390
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    111159390
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    111159390
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    111159390
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:elk03000]
    111159390
Transcription factors [BR:elk03000]
 Eukaryotic type
  Basic helix-loop-helix (bHLH)
   Factors with PAS domain
    111159390
SSDB
Motif
Pfam: PAS_3 HIF-1a_CTAD PAS_11 HIF-1 PAS PAS_9 PAS_4 HLH DDRGK
Other DBs
NCBI-GeneID: 111159390
NCBI-ProteinID: XP_022377520
UniProt: A0A2Y9L7U8
LinkDB
Position
Unknown
AA seq 823 aa
MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK
TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV
LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET
DDQQLEEVPLYNDVMLPSSNEKLQNINLAMSPLPASETPKPLRSSADPALNQEVALKLEP
NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNEFKLELVEKLF
AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTSPQSASTITVFQ
PTQMQEPPVTTTSTTATTDELKTVTKDGIEDIKILIASPSPTHVPKVTTSATTSPYSDTG
SRTASPNRAGKGVIEQTEKSHPRSPNVLSVTLSQRTTIPEEELNPKILALQNAQRKRKIE
HDGSLFQAVGIGTLLQQPDDRATTTSLSWKRVKGCKSSEHSGMEQKTIILIPSDLACRLL
GQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq 2472 nt   +upstreamnt  +downstreamnt
atggagggcgccggcggcgcgaacgacaagaaaaagataagttctgaacgtcgaaaagaa
aagtctagagatgcagctagatctcggcgaagtaaagagtccgaagtgttttatgagctt
gctcatcagttgccactcccccataatgtgagctctcatcttgataaggcttctgttatg
aggctgaccatcagctatttgcgtgtaaggaaacttctggatgctggtgatttagatatt
gaagatgaaatgaaagcacagatgaattgcttttatttgaaagctctggatggttttgtt
atggtactcacagatgatggtgacatgatttatatttctgataatgtgaacaaatacatg
ggattgactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac
catgaggaaatgagagaaatgcttacacacagaaatggccttgtgaaaaagggtaaagag
cagaatacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgggggaga
actatgaacataaagtcagcaacttggaaggtacttcactgcacaggccatattcatgtc
tacgatactaatagtaaccaatctcagtgtgggtataagaaaccacctatgacgtgcttg
gtgctgatttgtgaacccattcctcatccatcaaatattgaaattcctttagatagcaag
acttttctcagtcgtcacagtctggatatgaaattttcttattgtgatgaaagaattact
gaattgatgggatatgagccagaagaacttttgggccgctcaatttatgaatattatcat
gctttggactctgaccatctgaccaaaactcatcatgatatgtttactaaaggacaagtc
accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa
gcaactgtcatatataacactaagaattctcaaccacagtgcattgtatgtgtaaattat
gtggtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc
ctcaaaccagttgaatcttcagatatgaaaatgactcagctattcaccaaagttgaatca
gaagatacaagtagtctctttgataaacttaagaaggaacctgatgctttaactttgctg
gccccagctgctggagacacaatcatatctttagatttcggcagcaatgacacagaaact
gatgaccagcaacttgaggaagttccattgtataatgatgtaatgctcccctcatccaat
gaaaaattacagaatataaatttggcaatgtctccattacctgcttctgaaactccaaag
ccacttcgaagtagtgctgaccctgcactcaatcaagaagttgcgttaaaattagagcca
aatccagagtcactggaactgtcttttactatgccccagattcaagatcagccagctagt
ccttctgatggaagcactagacaaagttcacctgagcctaacagtcccagtgaatattgt
tttgatgtggatagtgatatggtcaatgaatttaagctggaattggtagagaaacttttt
gctgaagacacagaagcaaagaatccattttccacccaggacactgatttagacctggag
atgttagctccttatatcccaatggatgatgacttccagttacgttccttcgatcagctg
tcgccactggaaagcagttctacaagccctcaaagtgcaagcacaattacagtattccag
ccgactcaaatgcaggaacctcctgttaccactaccagtaccactgctaccactgatgaa
ttaaaaacagtgacaaaagatggtatagaagacattaaaatattgattgcatccccatct
cctacccacgtacctaaagtaactactagtgccacaacatcaccttacagtgatactgga
agtcggacagcctcaccaaacagagcaggaaaaggagtcatagaacaaacagaaaaatct
catccaagaagccctaatgtgttatctgtcactttgagtcaaagaaccaccattcctgag
gaagaactaaatccaaagatactagctttgcagaatgctcagagaaagcgaaaaatagaa
catgatggttcactttttcaagcagtaggaattggaactttattacagcagccagacgat
cgtgcaactactacgtcactttcttggaaacgcgtaaaaggatgcaaatctagtgaacac
agtggaatggagcaaaagacaattattttaataccctctgatttagcatgtagactgctg
gggcaatcaatggatgagagtggattaccacaactgaccagttatgattgtgaagttaat
gctcctatacaaggcagcagaaacctactgcagggtgaagaattactcagagctttggat
caagttaactga

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