Escherichia coli W: WFL_02225
Entry
WFL_02225 CDS
T02101
Gene name
ddlA
Definition
(GenBank) D-alanyl-alanine synthetase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
ell
Escherichia coli W
Pathway
ell00473
D-Alanine metabolism
ell00550
Peptidoglycan biosynthesis
ell01100
Metabolic pathways
ell01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ell00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00473 D-Alanine metabolism
WFL_02225 (ddlA)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
WFL_02225 (ddlA)
09160 Human Diseases
09175 Drug resistance: Antimicrobial
01502 Vancomycin resistance
WFL_02225 (ddlA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
ell01011
]
WFL_02225 (ddlA)
Enzymes [BR:
ell01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
WFL_02225 (ddlA)
Peptidoglycan biosynthesis and degradation proteins [BR:
ell01011
]
Precursor biosynthesis
Amino acid ligase
WFL_02225 (ddlA)
SSDB
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATPgrasp_ST
ATP-grasp_4
RimK
GARS_A
Other DBs
NCBI-ProteinID:
AFH10116
UniProt:
E0J0V3
LinkDB
Position
complement(475921..477015)
AA seq
364 aa
MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGIDKQGQWHVSDASNYLLN
ADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLLTVDVIFPIVHGTLGEDGSLQGML
RVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFITLTRANRHNISFAEVESKLGL
PLFVKPANQGSSVGVSKVTSEEQYAIAVDLAFEFDHKVIVEQGIKGREIECAVLGNDNPQ
ASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAPEINDKIRAIAVQAYQTLGCAGMAR
VDVFLTPENEVVINEINTLPGFTNISMYPKLWQASGLGYTDLITRLIELALERHAADNAL
KTTM
NT seq
1095 nt
+upstream
nt +downstream
nt
atggaaaaactgcgggtaggaatcgtttttggtggtaaatcagcggaacatgaagtgtct
ctgcaatcggcaaaaaacattgtcgatgccattgataaaagtcgcttcgacgttgtgctg
ctgggcattgataaacaagggcaatggcacgtcagcgatgccagcaattatctgctaaat
gcagacgatcctgcccatattgcgttacgcccttcggcgaccagccttgcgcaggtgcca
ggtaaacatgagcatcagcttatcgacgcgcaaaacggtcagccgttgctgacggtggat
gtcattttcccgattgtccacggtacgctgggcgaagatggttccttgcagggaatgctg
cgggtcgccaatttaccgtttgtaggttctgatgttctggcttcagcagcctgtatggat
aaagatgtcaccaaacgtctgctacgcgatgccgggctgaacattgcgccatttattact
ctgacgcgcgctaatcgtcacaacatcagttttgccgaagtggagtctaaactggggtta
ccactgtttgtaaaaccggctaatcagggctcttctgttggtgtcagcaaagtaaccagt
gaagaacagtacgcaattgccgtcgatctggcgttcgagttcgatcataaagtgatcgtt
gagcaagggatcaaaggtcgtgagatcgaatgcgcagttctgggcaacgacaatccgcaa
gccagcacctgtggcgagatcgtactcaccagcgatttctatgcctacgacaccaagtac
attgacgaagatggcgcgaaagtggtagttccggcagccattgcaccagagatcaacgat
aagatccgggcgattgccgttcaggcttatcagacgttgggatgcgcaggcatggcgcgt
gtagacgtgtttttaaccccagagaacgaagtggtgatcaacgagatcaacacactgcct
ggcttcaccaacatcagtatgtatccgaagctgtggcaagccagcggtctgggttacacc
gatctgatcacacgtttgattgagctggcgctggagcgtcacgctgcggataacgcattg
aaaaccacaatgtaa
DBGET
integrated database retrieval system
