KEGG   Escherichia coli W: ECW_m0073
Entry
ECW_m0073         CDS       T02002                                 
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
  KO
K00052  3-isopropylmalate dehydrogenase [EC:1.1.1.85]
Organism
elw  Escherichia coli W
Pathway
elw00290  Valine, leucine and isoleucine biosynthesis
elw00660  C5-Branched dibasic acid metabolism
elw01100  Metabolic pathways
elw01110  Biosynthesis of secondary metabolites
elw01210  2-Oxocarboxylic acid metabolism
elw01230  Biosynthesis of amino acids
Module
elw_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:elw00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    ECW_m0073 (leuB)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    ECW_m0073 (leuB)
Enzymes [BR:elw01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.85  3-isopropylmalate dehydrogenase
     ECW_m0073 (leuB)
SSDB
Motif
Pfam: Iso_dh DUF6259
Other DBs
NCBI-ProteinID: ADT73624
UniProt: E0IYV4
LinkDB
Position
complement(82542..83633)
AA seq 363 aa
MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPA
TVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAF
CPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTELYHRFEIERIARIAF
ESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQF
DVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIA
QILSLALLLRYSLDADDAACAIERAINRALEEGIRTGDLARGAAAVSTDEMGDIIARYVA
EGV
NT seq 1092 nt   +upstreamnt  +downstreamnt
atgtcgaagaattaccatattgccgtattgccgggggacggtattggtccggaagtgatg
acccaggcgctgaaagtgctggatgccgtgcgcaaccgctttgcgatgcgcatcaccacc
agccattacgatgtaggcggcgcagccattgataaccacgggcaaccactgccgcctgcg
acggttgaaggttgtgagcaagccgatgccgtgctgtttggctcggtaggcggtccgaaa
tgggaacatttaccaccagaccagcaaccagaacgcggcgcgctgttgcctttgcgtaag
cacttcaaattattcagcaacctgcgcccggcaaaactgtatcaggggctggaagcattc
tgtccgctgcgtgcagacattgccgctaacggcttcgacatcctgtgcgtgcgcgaactg
accggcggcatctatttcggtcagccaaaaggccgcgaaggtagcggacaatatgaaaaa
gcgtttgataccgagttgtatcaccgttttgagatcgagcgtattgcccgcatcgcgttt
gaatctgctcgtaaacgtcgccacaaagtcacctcaatcgacaaagctaacgtgctgcaa
tcctctattttatggcgtgaaatcgtcaacgagatcgccacggaatacccggatgtcgaa
ctggcgcatatgtacatcgacaacgccaccatgcagctgattaaagatccatcacagttt
gacgttctgctgtgctccaacctgtttggcgacattctgtctgacgagtgcgcaatgatc
actggctcgatggggatgttgccttccgccagcctgaacgagcaaggttttggtctgtat
gaaccggcaggcggctcagcaccagatatcgcaggcaaaaacatcgccaacccgattgcg
caaattctgtcgctggcactgctgctgcgctacagcctggatgccgatgatgcggcttgc
gccattgaacgcgccattaaccgcgcattagaagaaggcattcgcaccggggatttagcc
cgtggcgctgccgccgttagtaccgatgaaatgggcgatatcattgcccgctatgtggca
gaaggggtgtaa

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