Escherichia sp. E4742: FEM44_02775
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Entry
FEM44_02775 CDS
T06276
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
esz
Escherichia sp. E4742
Pathway
esz00230
Purine metabolism
esz01100
Metabolic pathways
esz01110
Biosynthesis of secondary metabolites
Module
esz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
esz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
FEM44_02775 (purL)
Enzymes [BR:
esz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
FEM44_02775 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
QCT86234
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Position
complement(585228..589115)
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNEEAHAQLERLLK
YGPALASHAPEGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYVEAATLT
NEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDYHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGLGTNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFA
GHCGIEADIASLGDDHLAALFNEELGAVIQVRAADREAVEAVLAQHGLAECVHYVGQAVS
GDRFVITANGQSVYSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPFIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEDFHALVACGGFSYGDVLGAGEGWAKSILFNNRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcactgtcggcattccgaatcaataaactgctg
gcgcgttttcaggctgccaggctcccggttcacaacatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgaagaagcgcacgcgcaacttgaacgcctgttgaaa
tatggtccggcactcgccagccatgccccggaaggcaaattactgctggtgaccccgcgt
ccaggcaccatctctccctggtcttcaaaagcgaccgatatcgcccataactgcgggctg
caacaggtaaaccgccttgagcgcggcgtggcttactatgtagaagccgctacgctgacc
aatgaacagtggcagcaggttaccgctgaactgcacgaccgcatgatggaaacggtcttt
tttgctttagatgatgcagagcagctgtttgcccatcatcaaccgactccagtcaccagc
gttgatttactggggcagggccgtcaggcgctgatcgacgcaaacctgcgtcttggcctg
gcactggcggaagatgaaattgactatctgcaagatgctttcacaaagcttggtcgtaac
ccgaacgacatcgagttgtatatgttcgcccaggcgaactctgagcactgccgtcataag
atttttaacgccgactggattatcgacggtgaacagcagccgaaatcgctgttcaaaatg
atcaaaaataccttcgaaaccacgccggatcacgttctctctgcgtataaagataacgcc
gcggtgatggaaggttctgaagtgggccgctactttgctgaccacgaaacgggccgctac
gattatcatcaggaaccggctcacatcctgatgaaagtagaaactcacaaccacccgacg
gcgatttctccgtggccgggcgcggcgaccggttccggcggtgaaatccgcgatgaaggt
gccaccgggcgcggcgcgaagccgaaagccggtctggttggtttctccgtttccaacctg
cgaattcctggcttcgaacagccgtgggaagaagatttcggtaagcctgagcgcattgtc
accgcgctggacatcatgactgaaggtccgctgggcggcgcggcatttaacaacgaattt
ggtcgtccggcgctgaacggctacttccgtacttatgaagaaaaagtgaacagccacaac
ggcgaagagctgcgcggttatcacaaaccgatcatgctggcaggcgggatcggtaatatc
cgcgccgatcacgtacaaaaaggcgagatcaacgtcggtgcgaagctggtcgttctcggc
ggcccggcaatgaacatcggtcttggcggcggcgcggcgtcttctatggcgtctggtcag
tctgatgccgacctcgactttgcttccgtacagcgcgacaacccggagatggagcgtcgc
tgccaggaagtgatcgaccgttgctggcagcttggtgatgccaacccaatcctgtttatc
cacgacgttggtgcaggcggtctttctaacgccatgccggaactggtgagtgacggcggg
cgcggcggtaaatttgaactgcgcgatatcctgagcgacgaaccgggtatgagcccactg
gaaatctggtgtaacgaatcccaggaacgctacgtgctggcggttgctgccgatcagtta
ccgctgtttgacgaactgtgtaagcgtgaacgcgcgccatacgcggtgattggtgaagcg
accgaagagctgcatctttctctgcacgatcgtcattttgataatcagccgatcgatcta
ccgctggacgtactgcttggcaaaacgccgaagatgacccgcgatgtgcaaacgctgaaa
gcaaaaggcgatgcgctggcccgtgaagggatcaccattgctgatgcggtgaaacgtgtg
ctgcatctgccgaccgtggcggagaaaactttccttgtgaccattggcgaccgtagcgta
accggcatggtggcgcgcgatcagatggttggcccgtggcaggtgccggtcgctaactgt
gcggtcactactgccagcctcgacagctactacggtgaagcgatggcaattggcgaacgt
gcgccagttgcactgctggatttcgccgcttctgcccgtctggcggtcggtgaagcgtta
accaacatcgccgcaacacaaattggcgatatcaaacgcattaaactttccgccaactgg
atggcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagctgtg
ggcgaagagctttgcccggcgctgggcctgacgatcccggtgggtaaagattcaatgtcg
atgaaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgctgtcgctg
gtgatttctgcatttgcccgcgtggaagatgtacgtcacaccatcacgccgcagctttct
accgaagataatgcactgctgctgattgatctgggccttggcactaacgcgttgggtgca
acggcgctggcgcaggtttatcgtcagcttggcgacaaaccggctgatgtgcgcgacgtc
gcgcaactgaaaggtttctatgacgcgattcaggcgctggttgcacagcgtaagctgctc
gcgtaccacgaccgctctgacggtggcctgctggtaacgctggcggaaatggcatttgcc
ggtcattgcggcattgaagcggatatcgcctctctgggcgacgatcacctggcggcgctg
tttaacgaagaactgggagcggtgattcaggttcgtgccgctgaccgtgaagcggtcgaa
gcggtactggcacagcatggccttgctgagtgcgtccattatgtcggccaggcggtatct
ggcgatcgttttgtgattaccgccaacggccagtcggtatacagcgaaagccgtactacg
ttgcgcgtctggtgggcagaaaccacctggcagatgcagcgcctgcgtgacaacccggag
tgcgccgatcaggaacatcaggcgaaatccaacgacgctgatccgggcctgaatgtgaaa
ctgtcgttcgatatcaacgaagatgtggcagctccgtttatcgctactggcgcgcgcccg
aaagttgccgtactgcgtgagcaaggcgtgaactcgcatgttgaaatggcggcagctttc
catcgtgcgggcttcgacgctatcgacgtgcatatgagcgatctgctggctggacgcact
ggtctggaggatttccacgccctggtcgcgtgtggtggtttctcctacggtgatgtgctg
ggtgccggtgaaggttgggcgaagtctattctgttcaacaaccgtgtacgcgatgagttt
gcaaccttcttccatcgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaatctgcgtgagctgatcccaggtagcgagctgtggcctcgtttcgtgcgtaac
acctccgatcgctttgaagcgcgtttcagcttggttgaagtgacccaaagcccgtctctg
ctgttgcaggggatggtgggctcgcagatgccgattgctgtgtctcacggtgaagggcgc
gttgaagtacgcgacgcggcgcatctggcggcactggaaagcaaagggctggttgcgctg
cgctatgtcgataatttcggcaaagtcactgaaacctacccggctaacccgaacggttcc
ccgaacggtattacggcggtcactaccgaaagcggtcgtgtcaccattatgatgccgcac
ccggaacgtgttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggat
ggcccatggatgcgtattttccgtaatgcgcgtaagcagctggggtaa
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