KEGG   Felis catus (domestic cat): 101083686
Entry
101083686         CDS       T02385                                 

Gene name
HIF1A
Definition
(RefSeq) hypoxia-inducible factor 1-alpha
  KO
K08268  hypoxia-inducible factor 1 alpha
Organism
fca  Felis catus (domestic cat)
Pathway
fca04066  HIF-1 signaling pathway
fca04137  Mitophagy - animal
fca04140  Autophagy - animal
fca04659  Th17 cell differentiation
fca04919  Thyroid hormone signaling pathway
fca05167  Kaposi sarcoma-associated herpesvirus infection
fca05200  Pathways in cancer
fca05205  Proteoglycans in cancer
fca05211  Renal cell carcinoma
fca05230  Central carbon metabolism in cancer
fca05231  Choline metabolism in cancer
fca05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    101083686 (HIF1A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101083686 (HIF1A)
   04137 Mitophagy - animal
    101083686 (HIF1A)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    101083686 (HIF1A)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    101083686 (HIF1A)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101083686 (HIF1A)
   05205 Proteoglycans in cancer
    101083686 (HIF1A)
   05230 Central carbon metabolism in cancer
    101083686 (HIF1A)
   05231 Choline metabolism in cancer
    101083686 (HIF1A)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101083686 (HIF1A)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    101083686 (HIF1A)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    101083686 (HIF1A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:fca03000]
    101083686 (HIF1A)
Transcription factors [BR:fca03000]
 Eukaryotic type
  Basic helix-loop-helix (bHLH)
   Factors with PAS domain
    101083686 (HIF1A)
SSDB
Motif
Pfam: PAS_3 HIF-1a_CTAD PAS_11 HIF-1 PAS PAS_9 PAS_4 HLH DDRGK
Other DBs
NCBI-GeneID: 101083686
NCBI-ProteinID: XP_003987765
Ensembl: ENSFCAG00000003427
LinkDB
Position
B3
AA seq 824 aa
MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK
TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV
LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET
DDQQLEEVPLYNDVMLPSSNEKLQNINLAMSPLPASETPKPLRSSADPALNQEVVLKLEP
NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPTSPSEYCFDVDSDMVNEFKLELVEKLF
AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTSPQSVGTITVFQ
PAQMQEEPPVTTTSTTATTDELKTVTKDGIEDIKILIASPSPTHVPKVTTGATTSLYGDT
GSRTASPNRAGKGVIEQTEKSHPRSPNVLSVTLSQRTTIPEEELNPKILALQNAQRKRKI
EHDGSLFQAVGIGTLLQQPDDRATTTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRL
LGQSMDESGLPQLTSYDCEVNAPVQGSRNLLQGEELLRALDQVN
NT seq 2475 nt   +upstreamnt  +downstreamnt
atggagggcgccggcggcgcgaacgacaagaaaaagataagttctgaacgtcgaaaagaa
aagtctagagatgcagcgagatctcggcgaagtaaagagtctgaagttttctatgaactt
gctcatcagttgccacttccccataatgtgagctcgcatctcgataaggcttctgttatg
aggctcaccatcagctatttgcgtgtgaggaaacttctggatgctggtgatttagatatt
gaagatgaaatgaaggcacagatgaattgcttttatttgaaagccttggatggttttgtt
atggttctcacagatgatggtgacatgatctacatttctgataatgtgaataagtacatg
ggattaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac
catgaagaaatgagagaaatgcttacacatagaaatggccttgtgaagaagggtaaagag
cagaatacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgagggaga
accatgaacataaagtcagcaacatggaaagtacttcactgcacaggccatattcatgtc
tacgataccaatagtaaccaatctcagtgtgggtataagaaaccacccatgacgtgcttg
gtgctgatttgtgaacccattcctcatccatcaaatattgaaattcctttagatagcaag
acttttctgagtcgtcatagtctggatatgaaattttcttattgtgatgaaagaattact
gaattgatgggatacgagccagaggaacttttgggccgctcgatatatgaatattaccat
gctttggactctgaccatctgaccaaaactcatcatgacatgtttactaaaggccaagtc
accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa
gcgaccgtcatatataacactaagaactctcaaccacagtgcattgtatgtgtaaattac
gttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc
ctcaaaccagttgaatcttcagatatgaaaatgactcagctgttcaccaaagttgaatca
gaagacacaagtagtctgtttgataaacttaagaaggaacctgatgctttaactttgctg
gccccagctgctggagacacaatcatatctttagatttcggcagcaatgacacagaaact
gatgaccagcaacttgaggaagttccattgtataatgatgtaatgcttccctcatccaat
gaaaaattacagaacataaatttggcaatgtctccattacctgcttctgaaactccaaag
ccacttcgaagtagtgctgaccctgcactcaatcaagaagttgtactaaaattagagcca
aatccagagtcactggaactttcttttactatgccccagattcaagatcagccagctagt
ccttctgatggaagcactagacagagttcacctgagcctaccagtcccagtgaatattgt
tttgatgtggatagtgatatggtcaatgaatttaagctggaattggtagagaaacttttt
gctgaagacacagaagccaagaatccattttccacccaggacactgatttagacttggag
atgttagctccttacatcccaatggatgatgacttccagttacgttcctttgatcagttg
tcgccactggaaagcagttctacaagccctcaaagcgtgggcacaattacagtattccag
ccggctcaaatgcaggaggaacctcctgttaccactaccagtaccactgccaccactgat
gaattaaaaacagtgacaaaagatggtatagaagacattaaaatactgattgcatctcca
tctcctacccatgtacccaaagtaactactggtgccacaacatcactgtatggtgatact
ggaagtcggacagcctcaccaaacagagcaggaaaaggagtcatagaacagacagaaaaa
tctcatccaagaagccctaatgtgttatctgtcactttgagtcaaagaactaccattcct
gaagaagaactaaatccaaagatactagctttgcagaatgctcagagaaagcgaaaaata
gaacatgacggttcactttttcaagcagtaggaattggaacattattacagcagccagat
gatcgtgcaactactacatcactttcttggaaacgcgtaaaaggatgcaaatctagtgag
cagaatggaatggagcaaaagacaattattttaataccctctgatttagcatgtagactg
ctggggcaatcaatggatgagagtggattaccacaactgaccagttatgattgtgaagtt
aatgctcctgtacaaggcagcagaaacctactgcagggtgaagaattactcagagctttg
gatcaagttaactga

DBGET integrated database retrieval system