Francisella philomiragia subsp. philomiragia ATCC 25017: Fphi_0316
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Entry
Fphi_0316 CDS
T00652
Name
(GenBank) D-alanyl-D-alanine-adding enzyme
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
fph
Francisella philomiragia subsp. philomiragia ATCC 25017
Pathway
fph00300
Lysine biosynthesis
fph00550
Peptidoglycan biosynthesis
fph01100
Metabolic pathways
fph01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
fph00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Fphi_0316
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Fphi_0316
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Fphi_0316
Enzymes [BR:
fph01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Fphi_0316
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABZ86532
UniProt:
B0TZH3
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Position
complement(339820..341178)
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AA seq
452 aa
AA seq
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MIKSLKQLATQAGLEYIGEDVSIQTVSINSNEIKQDALFVAIVANRDGHDFIPSALSYGA
KALLVSKKQDINIPQVVCSNTIKGLRALAKEYRKSLKMPIISLTGSCGKTTVKEMIVTLL
GGKKVHFTQGNFNNYLGVPMTVLETPQDVDFAVIETGTSVAGEIKAAAEIIQPNVAMITN
VGASHLENLKTLDGVMIEKGELLKALPKDGFCIVNLDDERIPAYADKLDCNKITCSMSNQ
DADIIILDYQVIPELYDVKIRIFDKEYSYQLPNIGKHNLSNSMLAIASVVAARLEPNDFL
QNTQNIKNYKGRFSTEKLNDKLTLVDDTYNASAGAVQAAIADLAEFDGKKVIAITSMREL
GDEGQNYHRKMGQWLNKAGLDNIFLFGEKNLIKFALEEYEGSNVKYYDDKQQLNNDLLKV
LDGYKSQNTKLTVKGARSFKMEEVVKFVKENL
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgatcaaatcactaaaacaattagcaacacaggctggcttagaatatatcggcgaagat
gtatcaattcaaacagttagcattaattctaatgaaattaaacaagatgctttatttgtt
gcgattgtagctaatcgtgatgggcatgattttattccaagtgctttgagttatggcgca
aaagctttgttggtatcaaaaaaacaagatataaatattccacaagtagtttgtagtaat
actattaagggactacgagcattggcaaaagagtaccgtaagtctctgaaaatgccaatt
atctccttaacaggtagttgtggtaaaacaacggttaaagaaatgattgtaactctactt
ggtggtaaaaaagttcattttacacaaggtaattttaacaactatcttggtgtgcctatg
acagttttagaaactccacaggatgtcgattttgctgtgattgaaactggtacaagcgtt
gcaggcgagataaaagctgctgctgaaattatccagcctaatgttgcgatgattacaaat
gttggcgctagtcatttagagaaccttaaaacactagatggtgtaatgattgaaaaaggt
gagcttcttaaagctttgccaaaagatggtttttgcattgtaaatcttgatgatgaaaga
atacccgcttatgcagataaattagactgtaacaaaattacttgctcaatgagtaatcaa
gatgcagatataatcattttagattatcaggttataccagagttatacgatgttaagatt
agaatctttgacaaagaatatagctatcagttaccaaacataggtaaacataatttgtct
aacagtatgcttgcaatagcaagtgtggttgctgcaagattagaacctaatgatttctta
caaaatacgcaaaatatcaaaaactataaaggcagattctcaaccgaaaaactaaatgat
aagttaactcttgtagacgatacatacaatgctagtgctggtgctgtccaagctgctata
gcagatttagctgaatttgatggtaaaaaagttatagcaattacttcaatgagagaatta
ggtgatgagggccagaattatcatcgtaaaatgggacaatggctcaataaggctggcttg
gataatatatttttatttggcgaaaaaaatttaataaagtttgctttagaagagtatgaa
ggttcaaatgttaaatattatgatgataaacaacagttaaataatgatctattaaaagta
cttgatgggtataaatctcaaaatactaaacttactgtcaaaggagctagaagctttaag
atggaagaagttgtcaaatttgttaaggaaaacttataa
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