Gemmatirosa kalamazoonensis: J421_3072
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Entry
J421_3072 CDS
T03025
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
gba
Gemmatirosa kalamazoonensis
Pathway
gba00300
Lysine biosynthesis
gba00550
Peptidoglycan biosynthesis
gba01100
Metabolic pathways
gba01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
gba00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
J421_3072
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
J421_3072
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
J421_3072
Enzymes [BR:
gba01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
J421_3072
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AHG90609
UniProt:
W0RHL2
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All DBs
Position
3572866..3574275
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AA seq
469 aa
AA seq
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MSTPTPAPGATDFWTLDRVAAALHDVLRGAVPRGDEPLRAVSTDTRAVTSGDLFVALVGD
RFDAHDFLPNAVEKGAAALVVSDARRTAGLGVPVYEVGDTLVALGRLGRYWRRAWGGTVV
GVAGSNGKTSTKELLKAALGAARRVSATSGNLNNLVGVPLTLLAIPPETEIAIVEMGTNM
PGEIARLRAIAEPSVTVMTSIGEEHLEGLGDLAGVLREESDAFDDVELAVVPADQPEVAE
AAAGRARRVVRAGLDDGDLKTERWSIGGDGAGTLLVDGVEVRPAVRGVHNLRNTMLALAV
ARALGVSLDDAARGVAGMPQPSMRSAWSQLGGVTLINDAYNANPGSTRAALDLLVHAGSG
RQRVAVLGTMRELGAHGDRLHEEIARRALDAGIEVVAGVGDFADALERVASRDARVVTAR
EVEALWPLLEPRVSSDAVILLKASRGVALERIVPSLERWAGGEPASQQV
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
gtgagcacgcccacgccggcgccgggcgccaccgacttctggaccctcgaccgcgtcgcc
gcggcgctgcatgacgtgctgcgcggggcggtgccgcgcggcgacgagccgctgcgcgcc
gtgagcacggacacgcgcgccgtgacgtcgggcgacctgttcgtcgcgctcgtcggcgac
cggttcgacgcgcacgacttcctgcctaacgccgtggagaagggcgccgccgcgctcgtc
gtctccgacgcgcgccgcaccgcgggactcggcgtgccggtgtacgaggtgggcgacacg
ctcgtcgcgctcggccggctcgggcgctactggcggcgcgcgtggggcggcacggtcgtc
ggcgtggcgggctccaacggcaagacgagcacgaaggagctgctgaaggcggcgctcggc
gccgcgcgccgcgtctcggcgacgagcggaaacctgaacaacctcgtcggcgtgccgctc
acgctgctcgccatcccgccggagacggagatcgcgatcgtcgagatgggcacgaacatg
cccggcgagatcgcccgcctgcgcgcgatcgccgagccgtccgtgaccgtgatgacgtcg
atcggcgaggagcatctcgagggcctcggcgacctcgccggcgtgctgcgcgaggagagc
gacgcgttcgacgacgtggagctggcggtcgtacccgccgatcagcccgaggtggccgag
gcggccgcgggccgtgcgcgccgcgtcgtgcgcgcggggctcgacgacggcgacctgaag
acggagcggtggtcgatcggcggcgacggcgccggcacgctgctcgtcgacggcgtcgag
gtgcgacctgccgtgcgcggcgtgcacaacctgcgcaacacgatgctcgcgctcgccgtg
gcgcgcgcgctcggcgtgtcgctcgacgatgcggcgcgcggcgtcgcgggcatgccccag
ccgagcatgcgctcggcgtggtcgcagctcggcggcgtgacgctcatcaacgacgcgtac
aacgcgaaccccggcagcacgcgggccgcgctcgacctgctcgtgcacgccggcagcggt
cgccagcgcgtcgcggtgctcggcaccatgcgcgagctcggtgcgcacggcgatcggctg
cacgaggagatcgcgcgccgcgcgctcgacgccggcatcgaggtggtggcgggcgtcggc
gacttcgcggatgcgctggagcgcgtcgcgtcgcgcgatgcacgcgtcgtcacggcgcgc
gaggtcgaggcgctgtggccgctgctcgagccgcgcgtgtcgtccgatgcagtgatcctg
ttgaaggcctcgcgcggcgtcgcgctcgagcgcatcgtgccgtcgctcgagcggtgggca
ggaggagagcccgcgtcgcagcaagtatag
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