Gorilla gorilla gorilla (western lowland gorilla): 101126190
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Entry
101126190 CDS
T02442
Gene name
EGFR
Definition
(RefSeq) epidermal growth factor receptor isoform X1
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
ggo
Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo01521
EGFR tyrosine kinase inhibitor resistance
ggo01522
Endocrine resistance
ggo04010
MAPK signaling pathway
ggo04012
ErbB signaling pathway
ggo04014
Ras signaling pathway
ggo04015
Rap1 signaling pathway
ggo04020
Calcium signaling pathway
ggo04066
HIF-1 signaling pathway
ggo04068
FoxO signaling pathway
ggo04072
Phospholipase D signaling pathway
ggo04144
Endocytosis
ggo04151
PI3K-Akt signaling pathway
ggo04510
Focal adhesion
ggo04520
Adherens junction
ggo04540
Gap junction
ggo04630
JAK-STAT signaling pathway
ggo04810
Regulation of actin cytoskeleton
ggo04912
GnRH signaling pathway
ggo04915
Estrogen signaling pathway
ggo04921
Oxytocin signaling pathway
ggo04926
Relaxin signaling pathway
ggo04928
Parathyroid hormone synthesis, secretion and action
ggo04934
Cushing syndrome
ggo05160
Hepatitis C
ggo05163
Human cytomegalovirus infection
ggo05165
Human papillomavirus infection
ggo05171
Coronavirus disease - COVID-19
ggo05200
Pathways in cancer
ggo05205
Proteoglycans in cancer
ggo05206
MicroRNAs in cancer
ggo05210
Colorectal cancer
ggo05212
Pancreatic cancer
ggo05213
Endometrial cancer
ggo05214
Glioma
ggo05215
Prostate cancer
ggo05218
Melanoma
ggo05219
Bladder cancer
ggo05223
Non-small cell lung cancer
ggo05224
Breast cancer
ggo05225
Hepatocellular carcinoma
ggo05226
Gastric cancer
ggo05230
Central carbon metabolism in cancer
ggo05231
Choline metabolism in cancer
ggo05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ggo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101126190 (EGFR)
04012 ErbB signaling pathway
101126190 (EGFR)
04014 Ras signaling pathway
101126190 (EGFR)
04015 Rap1 signaling pathway
101126190 (EGFR)
04630 JAK-STAT signaling pathway
101126190 (EGFR)
04066 HIF-1 signaling pathway
101126190 (EGFR)
04068 FoxO signaling pathway
101126190 (EGFR)
04020 Calcium signaling pathway
101126190 (EGFR)
04072 Phospholipase D signaling pathway
101126190 (EGFR)
04151 PI3K-Akt signaling pathway
101126190 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101126190 (EGFR)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101126190 (EGFR)
04520 Adherens junction
101126190 (EGFR)
04540 Gap junction
101126190 (EGFR)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101126190 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
101126190 (EGFR)
04915 Estrogen signaling pathway
101126190 (EGFR)
04921 Oxytocin signaling pathway
101126190 (EGFR)
04926 Relaxin signaling pathway
101126190 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
101126190 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101126190 (EGFR)
05206 MicroRNAs in cancer
101126190 (EGFR)
05205 Proteoglycans in cancer
101126190 (EGFR)
05230 Central carbon metabolism in cancer
101126190 (EGFR)
05231 Choline metabolism in cancer
101126190 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101126190 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
101126190 (EGFR)
05212 Pancreatic cancer
101126190 (EGFR)
05225 Hepatocellular carcinoma
101126190 (EGFR)
05226 Gastric cancer
101126190 (EGFR)
05214 Glioma
101126190 (EGFR)
05218 Melanoma
101126190 (EGFR)
05219 Bladder cancer
101126190 (EGFR)
05215 Prostate cancer
101126190 (EGFR)
05213 Endometrial cancer
101126190 (EGFR)
05224 Breast cancer
101126190 (EGFR)
05223 Non-small cell lung cancer
101126190 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101126190 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
101126190 (EGFR)
05171 Coronavirus disease - COVID-19
101126190 (EGFR)
05163 Human cytomegalovirus infection
101126190 (EGFR)
05165 Human papillomavirus infection
101126190 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101126190 (EGFR)
01522 Endocrine resistance
101126190 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ggo01001
]
101126190 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ggo04147
]
101126190 (EGFR)
Enzymes [BR:
ggo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101126190 (EGFR)
Protein kinases [BR:
ggo01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
101126190 (EGFR)
Exosome [BR:
ggo04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
101126190 (EGFR)
Exosomal proteins of pancreatic cancer cells
101126190 (EGFR)
Exosomal proteins of bladder cancer cells
101126190 (EGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
Kinase-like
APH
GAPT
Kdo
Motif
Other DBs
NCBI-GeneID:
101126190
NCBI-ProteinID:
XP_030868665
Ensembl:
ENSGGOG00000007623
LinkDB
All DBs
Position
7
AA seq
1210 aa
AA seq
DB search
MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEV
VLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALA
VLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDF
QNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGC
TGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYV
VTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDTLSINATNIKHFK
NCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAF
ENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKL
FGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCN
ILEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVM
GENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVV
ALGIGLFMRRRHIIRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGS
GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI
CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAA
RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY
GVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK
FRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQ
QGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTED
SIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLN
TVQPTCVNSTFDGPSHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRV
APQSSEFIGA
NT seq
3633 nt
NT seq
+upstream
nt +downstream
nt
atgcgaccctccgggaccgccggggcagcgctcctggcgctgctggctgcgctctgcccg
gcgagtcgggctctggaggaaaagaaagtttgccaaggcacgagtaacaagctcacgcag
ttgggcacttttgaagatcattttctcagcctccagaggatgttcaataactgtgaggtg
gtccttgggaatttggaaattacctatgtgcagaggaattatgatctttccttcttaaag
accatccaggaggtggctggttatgtcctcattgccctcaacacagtggagcggattcct
ttagaaaacctgcagatcatcagaggaaatatgtactacgaaaattcctacgccttagca
gtcttatctaactatgatgcaaataaaaccggactgaaggagctgcccatgagaaattta
caggaaatcctgcatggcgccgtgcggttcagcaacaaccctgccctgtgcaacgtggag
agcatccagtggcgggacatagtcagcagtgactttctcagcaacatgtcgatggacttc
cagaaccacctgggcagctgccaaaagtgtgatccaagctgtcccaatgggagctgctgg
ggtgcaggagaggagaactgccagaaactgaccaaaatcatctgtgcccagcagtgctcc
gggcgctgccgtggcaagtcccccagtgactgctgccacaaccagtgtgccgcaggctgc
acgggcccccgggagagcgactgcctggtctgccgcaaattccgagacgaagccacgtgc
aaggacacctgccccccactcatgctctacaaccccaccacgtaccagatggatgtgaac
cccgagggcaaatacagctttggtgccacctgcgtgaagaagtgtccccgtaattatgtg
gtgacagatcacggctcgtgcgtccgagcctgtggggccgacagctatgagatggaggaa
gacggcgtccgcaagtgtaagaagtgcgaagggccttgccgcaaagtgtgtaacggaata
ggtattggtgaatttaaagacacactctccataaatgctacgaatattaaacacttcaaa
aactgcacctccatcagtggcgatctccacatcctgccggtggcatttaggggtgactcc
ttcacacatactccgcctctggatccacaggaactggatattctgaaaaccgtaaaggaa
atcacagggtttttgctgattcaggcttggcctgaaaacaggacggacctccatgctttt
gagaacctagaaatcatacgcggcaggaccaagcaacatggtcagttttctcttgcggtc
gtcagcctgaacataacatccttgggattacgctccctcaaggagataagtgatggagat
gtgataatttcaggaaacaaaaatttgtgctatgcaaatacaataaactggaaaaaactg
tttgggacctccggtcagaaaaccaaaattataagcaacagaggtgaaaacagctgcaag
gccacaggccaggtctgccatgccttgtgctcccccgagggctgctggggcccggagccc
agggactgcgtctcttgccggaatgtcagccgaggcagggaatgcgtggacaagtgcaac
attctggagggcgagccaagggagtttgtggagaactctgagtgcatacagtgccaccca
gagtgcctgcctcaggccatgaacatcacctgcacaggacggggaccagacaactgtatc
cagtgtgcccactacattgacggcccccactgcgtcaagacctgcccggcaggagtcatg
ggagaaaacaacaccctggtctggaagtacgcagatgccggccatgtgtgccacctgtgc
catccaaactgcacctacggatgcactgggccaggtcttgaaggctgtccaacgaatggg
cctaagatcccgtccattgccactgggatggtgggggccctcctcttgctgctggtggtg
gccctggggattggcctcttcatgcgaaggcgccacatcattcggaagcgcacgctgcgg
aggctgctgcaggagagggagcttgtggagcctcttacacccagtggagaagctcccaac
caagctctcttgaggatcttgaaggaaactgaattcaaaaagatcaaagtgctgggctcc
ggcgcgttcggcacggtgtataagggactctggatcccagaaggtgagaaagttaaaatt
cccgtcgctatcaaggaattaagagaagcaacgtctccgaaagccaacaaggaaatcctc
gatgaagcctacgtgatggccagcgtggacaacccccacgtgtgccgcctgctgggcatc
tgcctcacctccaccgtgcagctcatcacgcagctcatgcccttcggctgcctcctggac
tatgtccgggaacacaaagacaatattggctcccagtacctgctcaactggtgtgtgcag
atcgcaaagggcatgaactacttggaggaccgtcgcttggtgcaccgcgacctggcagcc
aggaacgtactggtgaaaacaccgcagcatgtcaagatcacagattttgggctggccaaa
ctgctgggtgcagaagagaaagaataccatgcagaaggaggcaaagtgcctatcaagtgg
atggcattggaatcaattttacacagaatctatacccaccagagtgatgtctggagctac
ggggtgaccgtttgggagttgatgacctttggatccaagccatatgacggaatccctgcc
agcgagatctcctccatcctggagaaaggagaacgcctccctcagccacccatatgtacc
atcgatgtctacatgatcatggtcaaatgctggatgatagacgcagatagtcgcccaaag
ttccgtgagttgatcatcgaattctccaaaatggcccgagacccccagcgctaccttgtc
attcagggggatgaaagaatgcatttgccaagccctacagactccaacttctaccgtgcc
ctgatggatgaagaagacatggacgatgtggtggatgccgacgagtacctcatcccacag
cagggcttcttcagcagcccctccacgtcacggactcccctcctgagctctctgagtgca
accagcaacaattccactgtggcttgcattgatagaaatgggctgcaaagctgtcccatc
aaggaagacagcttcttgcagcgatacagctcagaccccacaggcgccttgactgaggac
agcatagacgacaccttcctcccagtgcctgaatacataaaccagtccgttcccaaaagg
cccgctggctctgtgcagaatcctgtctatcacaatcagcctctgaaccccgcacccagc
agagacccacactaccaggacccccacagcactgcagtgggcaaccccgagtatctcaac
actgtccagcccacctgtgtcaacagcacattcgacggcccttcccactgggcccagaaa
ggcagccaccaaattagcctggacaaccctgactaccagcaggacttctttcccaaggaa
gccaagccaaatggcatctttaagggctccacagctgaaaatgcagaatacctaagggtc
gcgccacaaagcagtgaatttattggagcatga
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integrated database retrieval system
