Gorilla gorilla gorilla (western lowland gorilla): 101126764 Help Entry 101126764         CDS       T02442                                  Gene name PLA2G4C Definition (RefSeq) cytosolic phospholipase A2 gamma   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism ggo  Gorilla gorilla gorilla (western lowland gorilla) Pathway ggo00564   Glycerophospholipid metabolism ggo00565   Ether lipid metabolism ggo00590   Arachidonic acid metabolism ggo00591   Linoleic acid metabolism ggo00592   alpha-Linolenic acid metabolism ggo01100   Metabolic pathways ggo04010   MAPK signaling pathway ggo04014   Ras signaling pathway ggo04072   Phospholipase D signaling pathway ggo04217   Necroptosis ggo04270   Vascular smooth muscle contraction ggo04370   VEGF signaling pathway ggo04611   Platelet activation ggo04664   Fc epsilon RI signaling pathway ggo04666   Fc gamma R-mediated phagocytosis ggo04724   Glutamatergic synapse ggo04726   Serotonergic synapse ggo04730   Long-term depression ggo04750   Inflammatory mediator regulation of TRP channels ggo04912   GnRH signaling pathway ggo04913   Ovarian steroidogenesis ggo04921   Oxytocin signaling pathway ggo05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ggo00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     101126764 (PLA2G4C)    00565 Ether lipid metabolism     101126764 (PLA2G4C)    00590 Arachidonic acid metabolism     101126764 (PLA2G4C)    00591 Linoleic acid metabolism     101126764 (PLA2G4C)    00592 alpha-Linolenic acid metabolism     101126764 (PLA2G4C)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101126764 (PLA2G4C)    04014 Ras signaling pathway     101126764 (PLA2G4C)    04370 VEGF signaling pathway     101126764 (PLA2G4C)    04072 Phospholipase D signaling pathway     101126764 (PLA2G4C)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101126764 (PLA2G4C)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101126764 (PLA2G4C)    04664 Fc epsilon RI signaling pathway     101126764 (PLA2G4C)    04666 Fc gamma R-mediated phagocytosis     101126764 (PLA2G4C)   09152 Endocrine system    04912 GnRH signaling pathway     101126764 (PLA2G4C)    04913 Ovarian steroidogenesis     101126764 (PLA2G4C)    04921 Oxytocin signaling pathway     101126764 (PLA2G4C)   09153 Circulatory system    04270 Vascular smooth muscle contraction     101126764 (PLA2G4C)   09156 Nervous system    04724 Glutamatergic synapse     101126764 (PLA2G4C)    04726 Serotonergic synapse     101126764 (PLA2G4C)    04730 Long-term depression     101126764 (PLA2G4C)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101126764 (PLA2G4C)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     101126764 (PLA2G4C) Enzymes [BR:ggo01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      101126764 (PLA2G4C) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLA2_B Motif Other DBs NCBI-GeneID:  101126764 NCBI-ProteinID:  XP_030859780 Ensembl:  ENSGGOG00000013321 LinkDB All DBs Position 19 AA seq 677 aa AA seqDB search MRTRPRPRLRRTENFLTAVHHGKTEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSG GGLRAHIACLGVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFT RQEWDVAKSLQKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYP IFAAIDNDLQPSWQEARAPETWFEFTPHHAGFPALGAYVSITHFGSKFKKGRLVRTHPER DLTFLRGLWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSTGCLIFARLLRLQES SQGEHPPPEDEGGEPEHTWLTEMLENWTRTSLEKQEQPHEDPERKGTLSNFMDFVKKTGI CASKWEWGTTHNFLYKHGGIRDTIMSSRKHLHLVDAGLAINTPFPLVLSPTREVHLILSF DFSAGDPFEVIEKGLGAGPGWEVGCGEADFAEELRTRAGKRAMGRCWLGSPETQINSPIA PKAPAVCHIQRASDPKPSQTFPGPSSWQMTLPASASCLPIHTSLNCDSLAPHLCTSFPRG ARLQPRTRVFLLIWVSWANMSHPVHPWAWRMPGCLSRSCMFMHVAASLCSLLVLPEYPTP STWTSHIPHPVSGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMN VAGLYYPKDSARSCCLA NT seq 2034 nt NT seq  +upstreamnt  +downstreamnt atgcgcacacgccccagacccaggctcaggaggactgagaattttctgaccgcagtgcac catgggaagacagaagaaaaggcggccgtggagagacgaagacttcatgtgctaaaagct ctgaagaagctaaggattgaggccgatgaggccccagttgttgctgtgctgggctcaggc ggaggactgcgggctcacattgcctgccttggggtcctgagtgagatgaaagaacagggc ctgttggatgctgtcacgtaccttgcaggggtctctggatccacttgggcaatatcttct ctctacaccaacgatggtgacatggaagctctcgaggctgacctgaaacatcgatttacc cgacaggagtgggacgtggctaagagcctacagaaaaccatccaagcagcgaggtctgag aattactctctgaccgacttctgggcctacatggttatctctaagcaaaccagagaactg ccggagtctcatttatccaatatgaagaagcccgtggaggaagggacactaccctacccg atatttgcagccattgacaatgacctgcaaccttcctggcaggaggcaagagcaccagag acctggttcgagttcacccctcaccacgctggcttccctgcactgggggcctatgtttcc ataacccacttcggaagcaaattcaagaagggaagactggtcagaactcaccctgagaga gacctgactttcctgagaggtttatggggaagtgctcttggtaacactgaagtcattagg gaatacatttttgaccagttaaggaatctgaccctgaaaggtttatggagaagggctgtt gctaatgctaaaagcactggatgccttatttttgcccgattactgaggctgcaagaaagt tcgcaaggggaacatcctcccccagaagatgaaggcggtgagcctgaacacacctggctg actgagatgctcgagaattggaccaggacctccctggaaaagcaggagcagccccatgag gaccctgaaaggaaaggcacactcagtaactttatggattttgtgaagaaaacaggcatt tgcgcttcgaagtgggaatgggggaccactcacaacttcctgtacaaacacggtggcatc cgggacacgataatgagcagccggaagcacctccacctggtggatgctggtttagccatc aacactcccttcccactcgtgctgtccccgacgcgggaggttcacctcatcctctccttc gacttcagtgccggagatcctttcgaggtaatcgagaagggccttggggccggtcctggg tgggaggtgggctgcggcgaagctgactttgcggaggaactgaggacacgggctgggaag cgggcaatggggaggtgctggctgggaagtccagagacccaaatcaactcacccatcgct cccaaagcacccgcagtctgccacatccaacgagcttctgatccaaagccatcccagacc ttcccgggcccctcttcctggcagatgactctccccgcttctgcatcctgcctgcccatt cataccagtttgaactgcgacagcctagctcctcacctgtgcacctccttccccaggggt gcacgtctccagccccgaacgcgtgtcttcctgctcatctgggtttcctgggcaaatatg agtcatcctgtccacccctgggcctggaggatgccaggctgcctctctcggtcttgcatg tttatgcatgttgctgcctctctctgcagccttcttgtcctacctgaatatccaacccct tccacctggacatcccacattcctcatccagtctcaggtgatattgaggcatggagtgac acatacgacacattcaagctcgctgacacctacactctagatgtggtggtgctactcttg gcattagccaagaagaatgtcagggaaaacaagaagaagatccttagagagttgatgaac gtggccgggctctactacccgaaggatagtgcccgaagttgctgcttggcatag

Gorilla gorilla gorilla (western lowland gorilla): 101137812 Help Entry 101137812         CDS       T02442                                  Gene name PLA2G4E Definition (RefSeq) cytosolic phospholipase A2 epsilon   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism ggo  Gorilla gorilla gorilla (western lowland gorilla) Pathway ggo00564   Glycerophospholipid metabolism ggo00565   Ether lipid metabolism ggo00590   Arachidonic acid metabolism ggo00591   Linoleic acid metabolism ggo00592   alpha-Linolenic acid metabolism ggo01100   Metabolic pathways ggo04010   MAPK signaling pathway ggo04014   Ras signaling pathway ggo04072   Phospholipase D signaling pathway ggo04217   Necroptosis ggo04270   Vascular smooth muscle contraction ggo04370   VEGF signaling pathway ggo04611   Platelet activation ggo04664   Fc epsilon RI signaling pathway ggo04666   Fc gamma R-mediated phagocytosis ggo04724   Glutamatergic synapse ggo04726   Serotonergic synapse ggo04730   Long-term depression ggo04750   Inflammatory mediator regulation of TRP channels ggo04912   GnRH signaling pathway ggo04913   Ovarian steroidogenesis ggo04921   Oxytocin signaling pathway ggo05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ggo00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     101137812 (PLA2G4E)    00565 Ether lipid metabolism     101137812 (PLA2G4E)    00590 Arachidonic acid metabolism     101137812 (PLA2G4E)    00591 Linoleic acid metabolism     101137812 (PLA2G4E)    00592 alpha-Linolenic acid metabolism     101137812 (PLA2G4E)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101137812 (PLA2G4E)    04014 Ras signaling pathway     101137812 (PLA2G4E)    04370 VEGF signaling pathway     101137812 (PLA2G4E)    04072 Phospholipase D signaling pathway     101137812 (PLA2G4E)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101137812 (PLA2G4E)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101137812 (PLA2G4E)    04664 Fc epsilon RI signaling pathway     101137812 (PLA2G4E)    04666 Fc gamma R-mediated phagocytosis     101137812 (PLA2G4E)   09152 Endocrine system    04912 GnRH signaling pathway     101137812 (PLA2G4E)    04913 Ovarian steroidogenesis     101137812 (PLA2G4E)    04921 Oxytocin signaling pathway     101137812 (PLA2G4E)   09153 Circulatory system    04270 Vascular smooth muscle contraction     101137812 (PLA2G4E)   09156 Nervous system    04724 Glutamatergic synapse     101137812 (PLA2G4E)    04726 Serotonergic synapse     101137812 (PLA2G4E)    04730 Long-term depression     101137812 (PLA2G4E)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101137812 (PLA2G4E)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     101137812 (PLA2G4E) Enzymes [BR:ggo01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      101137812 (PLA2G4E) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLA2_B cPLA2_C2 C2 Motif Other DBs NCBI-GeneID:  101137812 NCBI-ProteinID:  XP_004056088 Ensembl:  ENSGGOG00000011824 UniProt:  G3R844 LinkDB All DBs Position 15 AA seq 868 aa AA seqDB search MRLQASEGCPGLGTNVFVPQSPQRDEEGSRSGRSFSEFEDTQDLDTRGLPPFCPMAPWGS EEGLSPCHLLTVRVIRMKNVRQADMLSQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNE SFNFQIQSRVKNVLELSVCDEDTVTPDDHLLTVLYDLTKLCFRKKTHVKFPLNPQGMEEL EVEFLLEESPSPPETLVTNGVLVSRQVSCLEVHAQSRRRRKREKMKDLLVMVNESFENTQ RVQPCLEPCCPTSACFQTAACFHYPKYFQSQVHVEVPKSHWSCGLCCCSRKNGPISQPLD CLSDGQVMTLPVGESYELHMKSTPCPETLDVRLGFSLCPAELEFLQKRKVVVAKALKQVL QLEEDLQEDEVPLIAIMATGGGTRSMTSMYGHLLGLQKLNLLDCASYITGLSGATWTMAT LYRDPDWSSKNLEPAIFEARRHVVKDKLPSLFPDQLRKFQEELRQRSQEGYRVTFTDFWG LLIETCLGDERNECKLSDQRAALSCGQNPLPIYLTINVKDDVSNQDFREWFEFSPYEVGL QKYGAFIPSELFGSEFFMGRLVKRIPESRICYMLGLWSSIFSLNLLDAWNLSHTSEEFFH RWTREKVQDIEDEPILPEIPKCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLS GLQLHTNYLQNGQFSRWKDTVLDGFPNQLTESANHLCLLDTAFFVNSSYPPLLRPERKAD LIIHLNYCAGSQTKPLKQTCEYCTVQNIPFPKYELPDENENLKECYLMENPQEPDAPIVT FFPLINDTFRKYKAPGVERSPEELEQGQVDIYGPKTPYATKELTYTEATFDKLVKLSEYN ILNNKDTLLQALRLAVEKKKRLKGQCPS NT seq 2607 nt NT seq  +upstreamnt  +downstreamnt atgcgtctccaggcctcggaaggctgtcctggcctgggaactaatgtgtttgtcccacag agcccacagagggatgaagaaggcagcaggtcaggaagaagtttcagtgagttcgaggat acacaggacctggacactcgtggtctcccacctttctgtcctatggctccttggggctct gaggaggggctgtctccatgccacctgttgacagtgagggtcatccggatgaaaaatgtc cggcaggctgacatgctgagccagacagactgttttgtgagcctctggctgcccaccgcc tctcagaagaagctgaggacaaggaccatctccaactgcccaaatccagagtggaatgaa agcttcaacttccagatccagagccgagtgaagaacgtgctagagttgagtgtctgtgat gaagacacagtgacacctgatgaccatctcctgacagttctctatgacctcaccaagctc tgtttccgaaagaaaacccacgtgaagtttccactcaacccgcagggcatggaagagctg gaggtggagttcctgctggaggagagtccctctccacctgagaccctcgtcaccaatggc gtgctggtgtctcgacaagtctcctgcctggaggttcatgcacaatccaggaggcggagg aagagggagaaaatgaaggacctcctggtgatggtgaatgaatcctttgagaacacccag cgtgtccagccctgcttggaaccctgctgcccaacctctgcctgcttccaaaccgctgcc tgcttccactaccccaagtacttccagtcccaggtgcacgtggaagtgcccaagagtcac tggagctgtgggctttgctgctgctctcgcaagaacggccccatcagccagcccctcgac tgcctttccgatggtcaggtgatgaccctgcctgtgggtgagagttatgaattacacatg aagtctacaccctgccctgagacactggacgtgcggctgggcttcagcctgtgcccagca gagctggagtttctgcagaagcggaaggtcgtggtggccaaggccctgaagcaggtgctg cagctggaggaagacctgcaggaggatgaggtgccgctgatagccatcatggccactggg ggtggaacaagatccatgacctccatgtatggccacctgctggggctgcagaagctgaac ctcctggactgtgccagctacatcactggtctatcaggggccacctggaccatggctacc ttgtaccgtgaccctgactggtcctccaaaaacttggagcctgctatctttgaggctcgg agacacgtggtaaaggacaagctaccctccctgttcccagaccagctccgcaaattccag gaggagctccggcagcgcagccaggaaggctacagggtcacctttacagacttctggggc ctgctgatagagacctgcctgggggacgagagaaatgaatgcaaactgtcagatcagcgt gctgctttaagctgcggccagaaccccctgcccatctacctcaccatcaatgtcaaggat gatgtaagcaaccaggacttcagagagtggttcgagttctccccctacgaggtgggcctg cagaagtatggggccttcatcccctccgagctcttcggctccgagttcttcatggggcgg ctggtgaagaggatcccggagtctcgaatctgctacatgctaggcctgtggagcagcatc ttctccctgaatctgctggatgcctggaatctgtcacacacctcggaggagtttttccac aggtggacaagggagaaagtgcaggacatcgaagacgagccaatcctgcctgaaatcccc aaatgtgatgctaacatcctggagaccacggtagtgatcccagggtcatggctgtccaat tctttccgagaaatccttacccatcgttccttcgtatctgagtttcacaacttcctgtct gggctgcagctgcacaccaactacctccagaatggccagttctctaggtggaaagacaca gtgctggatggtttcccaaaccagctgaccgagtccgcgaaccacctgtgcctgctggac actgcgttctttgtcaactccagctacccgcccctcctcaggccagagcgaaaagccgac ctcatcatccacctcaactactgtgctgggtcccagacaaagcccctgaaacaaacttgt gagtactgcactgtgcagaacatccccttccccaaatacgagctgccagatgagaatgaa aatctcaaggaatgctacctgatggagaacccccaggaacccgatgcccccatcgtgact ttcttcccactcatcaatgacactttccgaaaatacaaggcaccaggtgtagagcgaagc cctgaggagctggagcagggccaggtggacatttatggtcccaaaactccctatgccacc aaggagctgacatacacagaggccacctttgacaagctggtgaaactctcagagtataac atcctgaataataaggacactctcctccaggctctgcggctcgcagtggagaagaagaag cgcctgaagggccagtgtccctcctag

Gorilla gorilla gorilla (western lowland gorilla): 101138793 Help Entry 101138793         CDS       T02442                                  Gene name PLA2G4F Definition (RefSeq) cytosolic phospholipase A2 zeta   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism ggo  Gorilla gorilla gorilla (western lowland gorilla) Pathway ggo00564   Glycerophospholipid metabolism ggo00565   Ether lipid metabolism ggo00590   Arachidonic acid metabolism ggo00591   Linoleic acid metabolism ggo00592   alpha-Linolenic acid metabolism ggo01100   Metabolic pathways ggo04010   MAPK signaling pathway ggo04014   Ras signaling pathway ggo04072   Phospholipase D signaling pathway ggo04217   Necroptosis ggo04270   Vascular smooth muscle contraction ggo04370   VEGF signaling pathway ggo04611   Platelet activation ggo04664   Fc epsilon RI signaling pathway ggo04666   Fc gamma R-mediated phagocytosis ggo04724   Glutamatergic synapse ggo04726   Serotonergic synapse ggo04730   Long-term depression ggo04750   Inflammatory mediator regulation of TRP channels ggo04912   GnRH signaling pathway ggo04913   Ovarian steroidogenesis ggo04921   Oxytocin signaling pathway ggo05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ggo00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     101138793 (PLA2G4F)    00565 Ether lipid metabolism     101138793 (PLA2G4F)    00590 Arachidonic acid metabolism     101138793 (PLA2G4F)    00591 Linoleic acid metabolism     101138793 (PLA2G4F)    00592 alpha-Linolenic acid metabolism     101138793 (PLA2G4F)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101138793 (PLA2G4F)    04014 Ras signaling pathway     101138793 (PLA2G4F)    04370 VEGF signaling pathway     101138793 (PLA2G4F)    04072 Phospholipase D signaling pathway     101138793 (PLA2G4F)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101138793 (PLA2G4F)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101138793 (PLA2G4F)    04664 Fc epsilon RI signaling pathway     101138793 (PLA2G4F)    04666 Fc gamma R-mediated phagocytosis     101138793 (PLA2G4F)   09152 Endocrine system    04912 GnRH signaling pathway     101138793 (PLA2G4F)    04913 Ovarian steroidogenesis     101138793 (PLA2G4F)    04921 Oxytocin signaling pathway     101138793 (PLA2G4F)   09153 Circulatory system    04270 Vascular smooth muscle contraction     101138793 (PLA2G4F)   09156 Nervous system    04724 Glutamatergic synapse     101138793 (PLA2G4F)    04726 Serotonergic synapse     101138793 (PLA2G4F)    04730 Long-term depression     101138793 (PLA2G4F)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101138793 (PLA2G4F)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     101138793 (PLA2G4F) Enzymes [BR:ggo01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      101138793 (PLA2G4F) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLA2_B cPLA2_C2 C2 Motif Other DBs NCBI-GeneID:  101138793 NCBI-ProteinID:  XP_004056091 Ensembl:  ENSGGOG00000000369 UniProt:  G3S105 LinkDB All DBs Position 15 AA seq 849 aa AA seqDB search MLWALWPRWLADKMLPLLGAVLLQKREKRGPLWRHWRRETYPYYDLQVKVLRATNIRGAD LLSKADCYVQLWLPTASPSPAQTRIVANCSDPEWNETFHYQIHGAVKNVLELTLYDKDIL GSDQLSLLLFDLRSLKCGQPHKHTFPLNHQDSQELQVEFVLEKSQVPASEVITNGVLVAH PCLRIQGTLRGDGTAPREEYGSRQLQLAVPGAYEKPQLLPLQPHTEPGLPPTFIFHVNPV LSSRLHVELMELLAAVQSGPSVELEAQTSKLGEGGILLSSLPLGQEEQCSVALGEGQEVA LSMKVEMSSGDLDLRLGFDLCDGEQEFLDRRKQVVSKALQQVLGLSEAPDSGQVPVVAVL GSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYRDPAWSQVALQGPIE RAQVHVCSSKMGALSTERLQYYTQELGVRERSGHSVSLIDLWGLLVEYFLYQEENPAKLS DQQEAVRQGQNPYPIYTSVNVRTNLSGEDFAEWCEFTPYEVGFPKYGAYVPTELFGSELF MGRLLQLQPEPRICYLQGMWGSAFATSLDEIFLKTAGSGLSFLEWYRGSVNITDDCQKPQ LHNPSRLRTRLLTPQGPFSQAVLDIFTSRFTSAQSFNFTRGLCLHKDYVAGREFVAWKDT HPDAFPNQLTPMRDCLYLVDGGFAINSPFPLALLPQRAVDLILSFDYSLEAPFEVLKMTE KYCLDRGIPFPSIEVGPEDMEEARECYLFAKAEDPRSPIVLHFPLVNRTFRTHLAPGVER QTAEEKAFGDFIINRPDTPYGMMNFTYEPQDFDRLVALSRYNVLNNVETLKCALQLALDR HQARERAGG NT seq 2550 nt NT seq  +upstreamnt  +downstreamnt atgctttgggcactctggccaaggtggctggcagacaagatgctgcccctcctgggggca gtgctgcttcagaagagagagaagaggggccctctgtggaggcactggcggcgggaaacc tacccatactatgacctccaggtgaaggtgctgagggccacaaacatccggggcgcagac ctgctgtccaaagctgactgctatgtgcaactgtggctgcccacggcgtccccaagccct gcccagactaggatagtggccaactgcagtgaccccgagtggaatgagaccttccactac cagatccatggtgctgtgaagaacgtcctggagctcaccctctatgacaaggacatcctg ggcagcgaccagctctctctgctcctgtttgacctgagaagcctcaagtgtggccaacct cacaaacacaccttcccactcaaccaccaggattcacaagagctgcaggtggaatttgtt ctggagaagagccaggtgcctgcatctgaagtcatcaccaacggggttctggtggctcac ccctgtctgagaatccagggcacgctccggggagatgggacagccccacgggaagagtac ggctctaggcagctccagctggcagtgcctggggcctacgagaagccacagctcttgccc ctgcagcctcacacagagccaggcctcccacccacctttatcttccacgtgaacccagtg ctgagctccaggctacacgtggagctgatggagctgctggcagctgtgcagagtggcccc agcgtggagctggaggctcagaccagcaagctgggcgaggggggcatcctgctctcctct ctgcccctaggccaggaggaacagtgttctgtggccctcggggagggccaggaggtggct ctgagcatgaaggtggaaatgagctccggggacctagacctacgccttggctttgacctc tgtgacggggagcaggagtttctggacaggaggaagcaggtcgtgtccaaggccctgcag caagtgctgggattgagtgaggctccggacagtggccaggtgcctgtagtggctgtgttg ggttccgggggtggaacccgagccatgtcttctctgtacggcagcctggcagggttgcag gagctcggccttctagacactgtgacctacctgagtggggtctctgggtctacctggtgc atctccacactctacagggacccagcctggtcccaggtggccttgcagggccccattgag cgtgcccaggttcacgtctgcagcagtaagatgggagctttgtccacggagcggctacag tactacactcaggaactgggggtccgggagcgcagtggccacagcgtgtccctcatcgac ctctggggcctccttgttgagtatttcctgtaccaggaggagaaccctgccaagctgtct gaccaacaggaggcggtccgccagggtcagaacccttaccccatttacaccagcgtcaac gtccgcaccaacttgagtggggaagattttgcagagtggtgcgagttcacgccctatgag gttggcttccccaagtacggggcttatgttcccaccgagctcttcggctcagaactcttt atgggacgattgctgcagctccagcctgaaccccggatctgttacctgcaaggtatgtgg ggcagcgcctttgccaccagcctggatgagatcttcctaaagaccgccggctcgggcctc agcttcctggagtggtacagaggcagtgtgaatatcacagacgactgccagaagcctcag ctgcacaacccctcgaggctgcgaacgaggctcctcaccccgcaggggcccttctcccag gctgtgctggacatattcacctcccgcttcacttccgcccagagctttaacttcacccgg ggtctctgcttgcacaaggactatgtggctggcagggagttcgtggcctggaaagacaca cacccggacgccttccccaaccagctcacccccatgcgggactgcctgtacctggtggac ggaggctttgccatcaactctccgttcccactggctctgctgcctcagagagcagtggac ctcattctgtcctttgactattccttggaagccccttttgaggtcttgaagatgacagag aagtactgcctggaccgaggaatccccttccctagcatcgaggtgggccctgaggacatg gaggaggcccgtgagtgctatctgtttgccaaggctgaggacccccgctcccccattgtg ctgcacttccctcttgttaaccgtaccttccgcacacacctggccccaggtgtggagcga caaacagctgaggagaaggcctttggggactttatcatcaacaggccagacaccccctat ggcatgatgaacttcacctatgagccccaggactttgatcggctggtggccctcagtcga tacaacgtcctgaacaatgtggagaccttgaagtgcgccctccagctggctctggaccgg caccaggctcgggagagggcagggggctga

Gorilla gorilla gorilla (western lowland gorilla): 101147399 Help Entry 101147399         CDS       T02442                                  Gene name PLA2G4A Definition (RefSeq) cytosolic phospholipase A2   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism ggo  Gorilla gorilla gorilla (western lowland gorilla) Pathway ggo00564   Glycerophospholipid metabolism ggo00565   Ether lipid metabolism ggo00590   Arachidonic acid metabolism ggo00591   Linoleic acid metabolism ggo00592   alpha-Linolenic acid metabolism ggo01100   Metabolic pathways ggo04010   MAPK signaling pathway ggo04014   Ras signaling pathway ggo04072   Phospholipase D signaling pathway ggo04217   Necroptosis ggo04270   Vascular smooth muscle contraction ggo04370   VEGF signaling pathway ggo04611   Platelet activation ggo04664   Fc epsilon RI signaling pathway ggo04666   Fc gamma R-mediated phagocytosis ggo04724   Glutamatergic synapse ggo04726   Serotonergic synapse ggo04730   Long-term depression ggo04750   Inflammatory mediator regulation of TRP channels ggo04912   GnRH signaling pathway ggo04913   Ovarian steroidogenesis ggo04921   Oxytocin signaling pathway ggo05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ggo00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     101147399 (PLA2G4A)    00565 Ether lipid metabolism     101147399 (PLA2G4A)    00590 Arachidonic acid metabolism     101147399 (PLA2G4A)    00591 Linoleic acid metabolism     101147399 (PLA2G4A)    00592 alpha-Linolenic acid metabolism     101147399 (PLA2G4A)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101147399 (PLA2G4A)    04014 Ras signaling pathway     101147399 (PLA2G4A)    04370 VEGF signaling pathway     101147399 (PLA2G4A)    04072 Phospholipase D signaling pathway     101147399 (PLA2G4A)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101147399 (PLA2G4A)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101147399 (PLA2G4A)    04664 Fc epsilon RI signaling pathway     101147399 (PLA2G4A)    04666 Fc gamma R-mediated phagocytosis     101147399 (PLA2G4A)   09152 Endocrine system    04912 GnRH signaling pathway     101147399 (PLA2G4A)    04913 Ovarian steroidogenesis     101147399 (PLA2G4A)    04921 Oxytocin signaling pathway     101147399 (PLA2G4A)   09153 Circulatory system    04270 Vascular smooth muscle contraction     101147399 (PLA2G4A)   09156 Nervous system    04724 Glutamatergic synapse     101147399 (PLA2G4A)    04726 Serotonergic synapse     101147399 (PLA2G4A)    04730 Long-term depression     101147399 (PLA2G4A)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101147399 (PLA2G4A)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     101147399 (PLA2G4A) Enzymes [BR:ggo01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      101147399 (PLA2G4A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLA2_B C2 Motif Other DBs NCBI-GeneID:  101147399 NCBI-ProteinID:  XP_004028114 Ensembl:  ENSGGOG00000012337 UniProt:  G3R9G5 LinkDB All DBs Position 1 AA seq 749 aa AA seqDB search MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRT RHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVGEKKEV PFIFNQVTEMVLEMSLEVCSCPDLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEG LHSARDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSH PDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIG ETLIHNRMNTTLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYG TFMAPDLFGSKFFMGTIVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEE LENITTKHIVSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFN TREGRAGKVHNFMLGLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFERIYEPLDV KSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMN KLPFPKIDPYVFDREGLKECYVFKPKNPDMEKDCPTIIHFVLANINFRKYKAPGVPRETE EEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKEAMVESIEYRR QNPSRCSVSLSNVEARRFFNKEFLSKPKA NT seq 2250 nt NT seq  +upstreamnt  +downstreamnt atgtcatttatagatccttaccagcacattatagtggagcaccagtattcccacaagttt acggtagtggtattacgtgccaccaaagtgacaaagggggcctttggtgacatgcttgat actccagatccctatgtggaactttttatctctacaacccctgacagcaggaagagaaca agacatttcaataatgacataaaccctgtgtggaatgagacctttgaatttattttggat cctaatcaggaaaatgttttggagattacgttaatggatgccaattatgtcatggatgaa actctagggacagcaacatttactgtatcttctatgaaggtgggagagaagaaagaagtt ccttttattttcaaccaagtcactgaaatggttctagaaatgtctcttgaagtttgctca tgcccagacctacgatttagtatggctctgtgtgatcaggagaagactttcagacaacag agaaaagaacacataagggagagcatgaagaaactcttgggtccaaagaatagtgaagga ttgcattctgcacgtgatgtgcctgtggtagccatattgggttcaggtgggggtttccga gccatggtgggattctctggtgtgatgaaggcattatacgaatcaggaattctggattgt gctacctacattgctggtctttctggctccacctggtatatgtcaaccttgtattctcac cctgattttccagagaaagggccagaggagattaatgaagaactaatgaaaaatgttagc cacaatccccttttacttctcacaccacagaaagttaaaagatatgttgagtctttatgg aagaagaaaagctctggacaacctgtcacctttactgatatctttgggatgttaatagga gaaacactaattcataatagaatgaatactactctgagtagtttgaaggaaaaagttaat actgcacaatgccctttacctcttttcacctgtcttcatgtcaaacctgacgtttcagag ctgatgtttgcagattgggttgaatttagtccatacgaaattggcatggctaaatatggt acttttatggctcctgacttatttggaagcaaattttttatgggaacaatcgttaagaag tatgaagaaaaccccttgcatttcttaatgggtgtctggggcagtgccttttccatattg ttcaacagagttttgggcgtttctggttcacaaagcagaggctccacaatggaggaagaa ttagaaaacattaccacaaagcatattgtgagtaatgatagctcggacagtgatgatgaa tcacacgaacccaaaggcactgaaaatgaagatgctggaagtgactatcaaagtgataat caagcaagttggattcatcgtatgataatggccttggtgagtgattcagctttattcaat accagagaaggacgtgctgggaaggtacacaacttcatgctgggcttgaatctcaataca tcttatccactgtctcctttgagtgactttgccacacaggactcctttgatgatgatgaa ctggatgcagctgtagcagatcctgatgaatttgagcgaatatatgagcctctggatgtc aaaagtaaaaagattcatgtagtggacagtgggctcacatttaacctgccgtatcccttg atactgagacctcagagaggggttgatctcataatctcctttgacttttctgcaaggcca agtgactctagtcctccgttcaaggaacttctacttgcagaaaagtgggctaaaatgaac aagctcccctttccaaagattgatccttatgtgtttgatcgggaagggctgaaggagtgc tatgtctttaaacccaagaatcctgatatggagaaagattgcccaaccatcatccacttt gttctggccaacatcaacttcagaaagtacaaggctccaggtgttccaagggaaactgag gaagagaaagaaatcgctgactttgatatttttgatgacccagaatcaccattttcaacc ttcaattttcaatatccaaatcaagcattcaaaagactacatgatcttatgcacttcaat actctgaacaacatcgatgtgataaaagaagccatggttgaaagcattgaatatagaaga cagaatccatctcgttgctctgtttcccttagtaatgttgaggcaagaagatttttcaac aaggagtttctaagtaaacccaaagcatag

Gorilla gorilla gorilla (western lowland gorilla): 109025233 Help Entry 109025233         CDS       T02442                                  Gene name PLA2G4D Definition (RefSeq) cytosolic phospholipase A2 delta   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism ggo  Gorilla gorilla gorilla (western lowland gorilla) Pathway ggo00564   Glycerophospholipid metabolism ggo00565   Ether lipid metabolism ggo00590   Arachidonic acid metabolism ggo00591   Linoleic acid metabolism ggo00592   alpha-Linolenic acid metabolism ggo01100   Metabolic pathways ggo04010   MAPK signaling pathway ggo04014   Ras signaling pathway ggo04072   Phospholipase D signaling pathway ggo04217   Necroptosis ggo04270   Vascular smooth muscle contraction ggo04370   VEGF signaling pathway ggo04611   Platelet activation ggo04664   Fc epsilon RI signaling pathway ggo04666   Fc gamma R-mediated phagocytosis ggo04724   Glutamatergic synapse ggo04726   Serotonergic synapse ggo04730   Long-term depression ggo04750   Inflammatory mediator regulation of TRP channels ggo04912   GnRH signaling pathway ggo04913   Ovarian steroidogenesis ggo04921   Oxytocin signaling pathway ggo05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ggo00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     109025233 (PLA2G4D)    00565 Ether lipid metabolism     109025233 (PLA2G4D)    00590 Arachidonic acid metabolism     109025233 (PLA2G4D)    00591 Linoleic acid metabolism     109025233 (PLA2G4D)    00592 alpha-Linolenic acid metabolism     109025233 (PLA2G4D)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     109025233 (PLA2G4D)    04014 Ras signaling pathway     109025233 (PLA2G4D)    04370 VEGF signaling pathway     109025233 (PLA2G4D)    04072 Phospholipase D signaling pathway     109025233 (PLA2G4D)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     109025233 (PLA2G4D)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109025233 (PLA2G4D)    04664 Fc epsilon RI signaling pathway     109025233 (PLA2G4D)    04666 Fc gamma R-mediated phagocytosis     109025233 (PLA2G4D)   09152 Endocrine system    04912 GnRH signaling pathway     109025233 (PLA2G4D)    04913 Ovarian steroidogenesis     109025233 (PLA2G4D)    04921 Oxytocin signaling pathway     109025233 (PLA2G4D)   09153 Circulatory system    04270 Vascular smooth muscle contraction     109025233 (PLA2G4D)   09156 Nervous system    04724 Glutamatergic synapse     109025233 (PLA2G4D)    04726 Serotonergic synapse     109025233 (PLA2G4D)    04730 Long-term depression     109025233 (PLA2G4D)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     109025233 (PLA2G4D)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     109025233 (PLA2G4D) Enzymes [BR:ggo01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      109025233 (PLA2G4D) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  cPLA2_C2 PLA2_B C2 Motif Other DBs NCBI-GeneID:  109025233 NCBI-ProteinID:  XP_030858200 LinkDB All DBs Position 15 AA seq 818 aa AA seqDB search MESLSPGGPPGHPYQGEASTCWQLTVRVLEARNLRWADLLSEADPYVILQLSTAPGMKFK TKTLTDTSHPVWNEAFHFLIQSQVKNVLELSIYDEDSVTEDDICFKVLYDVSEVLPGKLL RKTFSQSPQGEEELDVEFLMEETSDRPENLITNKVLVARELSCLDVHLDSTGSTAVVADQ DKLELELVLKGSYEDTQTSFLGTASAFRFHYMAALETELSGRLRSSTSNGWNGDNSARYL TVPLRPLNIGKEVTMDVPAPNAPGVRLQLKAEGCPEELAVHLGFNLCAEEQAFLSRRKQV VAKALKQALQLDRDLQEDEVPVVGIMATGGGARAMTSLYGHLLALQKLGLLDCVTYFSGI SGSTWTMAHLYGDAEWSQRDLEGPIRYAREHLTKSKLEVFSPERLASYRRELELRAEQGY PTTFVDLWALVLESMLHGQVMDQKLSGQRAALERGQNPLPLYLSLNVKENNLETLDFKEW VEFSPYEVGFLKYGAFVPPELFGSEFFMGRLMRRIPEPRICFLEAIWSNIFSLNLLDAWY DLTSSGESWKQHIKDKTRSLEKEPLTTSGTSSRLEASWLQPGMALAQAFKGFLTGRPLHQ RSPNFLQGLQLHQDYRSHKDFSTWADCQLDSMPSQLTPQEARLCLVDAGYFINTSCPSMF RPGRRLDLILSFDYSLSAPFEALQQTELYCRARGLPFPRVEPSPLDQHQPRECHLFSDPA CPEAPILLHFPLVNASFKDHSAPGVQRSPAELQGGQVDLTGATCPYTLSNMTYKEEDFER LLRLSDYNVQTSQGAILQALRTALKHRTLEARPPRAQT NT seq 2457 nt NT seq  +upstreamnt  +downstreamnt atggagagcctgtcacctgggggaccacctggccacccttaccagggggaggcctctacc tgctggcagctcaccgtgagggtcctggaggcgcggaacctgcgctgggctgacctgttg agtgaggccgacccttacgtgatcctacagctgtcgaccgcacctggaatgaagtttaag accaagacgctcaccgacaccagtcatcctgtgtggaatgaggccttccatttccttatc caaagtcaggtcaagaatgttctggagcttagcatctatgatgaggactcagtcacggag gatgatatctgcttcaaggttctctatgacgtctcagaagtcctccctggcaagctgctc cggaaaaccttctcccagagtccccagggagaggaggagctggatgtggagttcctgatg gaagaaacgtcagatcgcccagaaaacctcatcaccaacaaagtccttgtggctcgagag ctgtcatgcctggatgtgcatctggacagcacagggagcaccgctgtggttgcagatcag gacaagctggagctggagctggtgctgaaggggtcctatgaggacacacagacatccttc ctgggcacagcctctgccttccgcttccactacatggcagccctagagacagagctgagc gggcgcctgaggagctccacaagcaatggctggaatggggacaactcagctcggtacctc actgtgcccctgaggcccttgaacattgggaaggaggtgactatggatgttcctgctcca aatgccccaggagtgaggctgcagctgaaggcagagggctgccctgaggagctggccgtg cacctgggcttcaatctctgtgcagaggagcaggccttcctgagcaggaggaagcaggtg gtggccaaggccctgaagcaggccctgcagctggacagagacctgcaggaggatgaggta cccgtcgtgggcatcatggccacaggaggaggtgcccgggccatgacctcgctctacggc cacctattggccttgcagaagctgggcctcctagactgtgtgacctacttcagtggcatc tctggctctacgtggacaatggcccacctgtacggggacgctgagtggtcgcagagggac ctggagggacctatcagatacgcccgggagcacctgaccaagagcaagctggaggtcttt tccccagagcgcctggcgagctaccgccgggagctggagctgcgggctgagcagggctac cccacgacttttgtggacctgtgggcgctagtgctggagtccatgctgcacggccaggtg atggatcagaagctgtcaggacagagagccgccctggaacggggtcagaaccctctgccc ctctacttgagcctcaatgtcaaagagaacaatctggagacactggacttcaaggagtgg gttgagttctccccctatgaggtcggtttcctgaagtacggggccttcgtccctcctgag ctcttcggctccgagttcttcatgggacggctgatgaggaggatcccggagccccggatc tgctttctggaagccatctggagcaacattttctccctgaacctgctggacgcctggtat gacctcaccagttctggggagtcctggaaacagcacatcaaggacaagaccaggagctta gagaaggagcccctgaccacctcggggacctcctcgcggctggaggcctcgtggctgcag ccaggcatggcgctggcccaggcatttaaaggcttcctgaccggcaggcccctccaccag cgcagccccaacttcctccagggcctccagctgcaccaggactaccgtagccacaaagac ttctccacctgggcagactgccagcttgactccatgcccagccagctgaccccccaggag gcccggctctgcctggtggacgccggctacttcatcaacactagctgtccctccatgttc cggccaggccgcaggctggacctcatcctctccttcgactactccctatctgcgcccttc gaggcgctgcagcagacggagctgtactgccgggcccgggggctgcccttcccccgggtg gaacccagccctctggaccagcaccagccaagggagtgccacctcttctcagaccccgcc tgccccgaggccccaatcctgctgcacttcccgctggtcaatgcctccttcaaggaccac tcagcccccggtgtccagcgcagccccgcagagctccagggtggccaagtggatctcacc ggggccacctgcccctacaccctgtccaacatgacctacaaggaggaagacttcgagcgc ctgctgcggctcagtgactacaacgtgcagaccagccagggtgccatcctgcaggccctg aggaccgcgctgaagcaccggaccctagaggcgaggcctccaagggcacagacctga

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