KEGG   Gorilla gorilla gorilla (western lowland gorilla): 101135038
Entry
101135038         CDS       T02442                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
ggo  Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo01521  EGFR tyrosine kinase inhibitor resistance
ggo04062  Chemokine signaling pathway
ggo04066  HIF-1 signaling pathway
ggo04068  FoxO signaling pathway
ggo04217  Necroptosis
ggo04550  Signaling pathways regulating pluripotency of stem cells
ggo04630  JAK-STAT signaling pathway
ggo04659  Th17 cell differentiation
ggo04917  Prolactin signaling pathway
ggo04920  Adipocytokine signaling pathway
ggo04931  Insulin resistance
ggo04933  AGE-RAGE signaling pathway in diabetic complications
ggo04935  Growth hormone synthesis, secretion and action
ggo05145  Toxoplasmosis
ggo05160  Hepatitis C
ggo05161  Hepatitis B
ggo05162  Measles
ggo05163  Human cytomegalovirus infection
ggo05167  Kaposi sarcoma-associated herpesvirus infection
ggo05169  Epstein-Barr virus infection
ggo05200  Pathways in cancer
ggo05203  Viral carcinogenesis
ggo05205  Proteoglycans in cancer
ggo05206  MicroRNAs in cancer
ggo05212  Pancreatic cancer
ggo05221  Acute myeloid leukemia
ggo05223  Non-small cell lung cancer
ggo05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ggo05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:ggo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    101135038 (STAT3)
   04066 HIF-1 signaling pathway
    101135038 (STAT3)
   04068 FoxO signaling pathway
    101135038 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    101135038 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101135038 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    101135038 (STAT3)
   04062 Chemokine signaling pathway
    101135038 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    101135038 (STAT3)
   04917 Prolactin signaling pathway
    101135038 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    101135038 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101135038 (STAT3)
   05206 MicroRNAs in cancer
    101135038 (STAT3)
   05205 Proteoglycans in cancer
    101135038 (STAT3)
   05203 Viral carcinogenesis
    101135038 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101135038 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    101135038 (STAT3)
   05221 Acute myeloid leukemia
    101135038 (STAT3)
   05223 Non-small cell lung cancer
    101135038 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    101135038 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    101135038 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101135038 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    101135038 (STAT3)
   05161 Hepatitis B
    101135038 (STAT3)
   05160 Hepatitis C
    101135038 (STAT3)
   05163 Human cytomegalovirus infection
    101135038 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101135038 (STAT3)
   05169 Epstein-Barr virus infection
    101135038 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101135038 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101135038 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ggo03000]
    101135038 (STAT3)
Transcription factors [BR:ggo03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    101135038 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 DUF4795
Other DBs
NCBI-GeneID: 101135038
NCBI-ProteinID: XP_018883231
Ensembl: ENSGGOG00000017110
LinkDB
Position
5
AA seq 865 aa
MTACLGQAGVGRGLAEGAVIQRFPELRRRRLGGGAGGSDVAAEGTSPNRILDRHPGLALS
LPLGSERPFGLREPRRPSPAHAQPRPLGLCRRNSRMAQWNQLQQLDTRYLEQLHQLYSDS
FPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRR
IKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLE
QHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQ
MLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLEN
WITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVER
QPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFN
ILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEV
YHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVA
EVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWL
DNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVE
KDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGK
YCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAE
PSAGGQFESLTFDMELTSECATSPM
NT seq 2598 nt   +upstreamnt  +downstreamnt
atgacggcgtgcctcggccaggctggggttgggcgaggattggctgaaggggctgtaatt
cagcggtttccggagctgcggcggcgcagactgggagggggagccgggggttccgacgtc
gcagccgagggaacaagccccaaccggatcctggacaggcaccccggcttggcactgtct
ctccccctcggctcggagaggcccttcggcctgagggagcctcgccgcccgtccccggcg
cacgcgcagccccggcccctcggcctctgccggagaaacagcaggatggcccaatggaat
cagctacagcagcttgacacacggtacctggagcagctccatcagctctacagtgacagc
ttcccaatggagctgcggcagtttctggccccttggattgagagtcaagattgggcatat
gcggccagcaaagaatcacatgccactttggtgtttcataatctcctgggagagattgac
cagcagtatagccgcttcctgcaagagtcgaatgttctctatcagcacaatctacgaaga
atcaagcagtttcttcagagcaggtatcttgagaagccaatggagattgcccggattgtg
gcccggtgcctgtgggaagaatcacgccttctacagactgcagccactgcggcccagcaa
gggggccaggccaaccaccccacagcagccgtggtgacggagaagcagcagatgctggag
cagcaccttcaggatgtccggaagagagtgcaggatctagaacagaaaatgaaagtggta
gagaatctccaggatgacttcgatttcaactataaaaccctcaagagtcaaggagacatg
caagatctgaatggaaacaaccagtcagtgaccaggcagaagatgcagcagctggaacag
atgctcactgcgctggaccagatgcggagaagcatcgtgagtgagctggcggggcttttg
tcagcgatggagtacgtgcagaaaactctcacggacgaggagctggctgactggaagagg
cggcaacagattgcctgcattggaggcccacccaacatctgcctagatcggctagaaaac
tggataacgtcattagcagaatctcaacttcagacccgtcaacaaattaagaaactggag
gagttgcagcaaaaagtttcctacaaaggggatcccattgtacagcaccggccgatgcta
gaggagagaatcgtggagctgtttagaaacttaatgaaaagtgcctttgtggtggagcgg
cagccctgcatgcccatgcatcctgaccggcccctcgttatcaagaccggcgtccagttc
actactaaagtcaggttgctggtcaaattccctgagttgaattatcagcttaaaattaaa
gtgtgcattgacaaagactctggggacgttgcagctctcagaggatcccggaaatttaac
attctgggcacaaacacaaaagtgatgaacatggaagaatccaacaacggcagcctctct
gcagaattcaaacacttgaccctgagggagcagagatgtggcaatgggggccgagccaat
tgtgatgcttccttgattgtgactgaggagctgcacctgatcacctttgagaccgaggtg
tatcaccaaggcctcaagattgacctagagacccactccttgccagttgtggtgatctcc
aacatctgtcagatgccaaatgcctgggcgtccatcctgtggtacaacatgctgaccaac
aatcccaagaacgtaaacttttttaccaagcccccaattggaacctgggatcaagtggcc
gaggtcctgagctggcaattctcctccaccaccaagcgaggactgagcatcgagcagctg
actacactggcagagaaactcttgggacctggtgtgaattattcagggtgtcagatcaca
tgggctaaattttgcaaagaaaacatggctggcaagggcttctccttctgggtctggctg
gacaatatcattgaccttgtgaaaaagtacatcctggccctttggaacgaagggtacatc
atgggctttatcagtaaggagcgggagcgggccatcttgagcactaagcctccaggcacc
ttcctgctaagattcagtgaaagcagcaaagaaggcggcgtcactttcacttgggtggag
aaagacatcagcggtaagacccagatccagtccgtggaaccatacacaaagcagcagctg
aacaacatgtcatttgctgaaatcatcatgggctataagattatggatgctaccaatatc
ctggtgtctccactggtctatctctaccctgacattcccaaggaggaggcattcggaaag
tattgtcggccagagagccaggagcatcctgaagctgacccaggtagcgctgccccatac
ctgaagaccaagtttatctgtgtgacaccaacgacctgcagcaataccattgacctgccg
atgtccccccgcactttagattcattgatgcagtttggaaataatggtgaaggtgctgaa
ccctcagcaggagggcagtttgagtccctcacctttgacatggagttgacctcggagtgc
gctacctcccccatgtga

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