| Entry |
|
|---|
| Name |
|
|---|
| Composition |
(Gal)1 (Glc)1 (Neu5Ac)1 (Cer)1
|
|---|
| Mass |
615.5 (Cer)
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Reaction |
|
|---|
| Pathway |
| map00604 | Glycosphingolipid biosynthesis - ganglio series |
|
|---|
| Module |
| M00069 | Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 |
|
|---|
| Enzyme |
|
|---|
| Orthology |
| K00725 | (N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase [EC:2.4.1.92] |
| K03370 | lactosylceramide alpha-2,3-sialyltransferase (sialyltransferase 9) [EC:2.4.99.9] |
| K03371 | alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8A) [EC:2.4.99.8] |
|
|---|
| Brite |
Compounds with biological roles [BR:br08001]
Lipids
Glycolipids
Glycosphingolipids
C04730 GM3
Lipids [BR:br08002]
SP Sphingolipids
SP06 Acidic glycosphingolipids
SP0601 Gangliosides
G00108 Neu5Ac-alpha2->3Gal-beta1->4Glc-beta1->1'Cer (GM3)
Cancer-associated carbohydrates [br08441.html]
G00108
Carbohydrates in viral and bacterial infections [br08431.html]
Viral infection
G00108
Bacterial infection
G00108
|
|---|
| Reference |
|
|---|
| Authors |
Larson G, Falk P, Hoskins LC. |
|---|
| Title |
Degradation of human intestinal glycosphingolipids by extracellular glycosidases from mucin-degrading bacteria of the human fecal flora. |
|---|
| Journal |
J Biol Chem 263:10790-8 (1988) |
|---|
| Reference |
|
|---|
| Authors |
Ideo H, Seko A, Yamashita K. |
|---|
| Title |
Galectin-4 binds to sulfated glycosphingolipids and carcinoembryonic antigen in patches on the cell surface of human colon adenocarcinoma cells. |
|---|
| Journal |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
NODE 4
1 Cer 13 0
2 Glc 5 0
3 Gal -3 0
4 Neu5Ac -13 0
EDGE 3
1 2:b1 1:1
2 3:b1 2:4
3 4:a2 3:3
|
|---|
