Gardnerella vaginalis 409-05: HMPREF0424_1233
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Entry
HMPREF0424_1233 CDS
T01146
Name
(GenBank) D-ala D-ala ligase N-terminal domain protein
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
gva
Gardnerella vaginalis 409-05
Pathway
gva00470
D-Amino acid metabolism
gva00550
Peptidoglycan biosynthesis
gva01100
Metabolic pathways
gva01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
gva00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
HMPREF0424_1233
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HMPREF0424_1233
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HMPREF0424_1233
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
gva01011
]
HMPREF0424_1233
Enzymes [BR:
gva01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
HMPREF0424_1233
Peptidoglycan biosynthesis and degradation proteins [BR:
gva01011
]
Precursor biosynthesis
Amino acid ligase
HMPREF0424_1233
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
ADB14041
LinkDB
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Position
complement(1466029..1467171)
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AA seq
380 aa
AA seq
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MTKKRVVFLYGGKADEHSISCISAAGVLSAVDENRFDIVRIAITKQGEWIVGGEDPRNFH
MEEGELPVITKTAGTRDVVLDPAKGADGFLARENDGTLTSLGHIDAVFPVLHGPNGEDGT
LQGLLEMMQVPYVGCGVLASAACMDKYYAKQLFKAAGIDVAPGIALDARKFASDAENRFD
AYAEEILAQVEAAKLEYPLFVKPSRAGSSFGVTKVESRDAKALAEAIFEASEHDWRVLVE
QGIDAREIECAVLAARDGEEPKASWPGEVVLDKREAGEDQFYDFDSKYMDSAASHVEVPA
NLPAETLERVRKTALAAFKAADGRGLSRVDSFVTKDGRVILNEINTMPGFTPISMYPKAW
EATGISYSDLITKLIEGVLK
NT seq
1143 nt
NT seq
+upstream
nt +downstream
nt
atgacgaaaaagcgtgtagtgttcttgtatggcggtaaggcagacgaacattcgatttct
tgcatatccgctgctggagtgctcagtgctgtagacgaaaatcgttttgacattgtgcgg
atcgcaatcacaaaacaaggcgaatggattgttggtggtgaagatcctcgtaacttccac
atggaagagggtgagttgccagtaatcacaaaaaccgctggaacgcgcgatgttgtgctt
gaccctgccaaaggcgcagacggatttttagcccgcgaaaatgacggtacacttacaagt
ttgggtcatattgacgcagttttcccagttcttcacggtccaaacggtgaagatggcact
ttgcaaggcttgctagaaatgatgcaagttccatacgttggttgtggagtgttggcttcg
gctgcgtgcatggataaatactatgcaaagcaactgtttaaagctgccggaattgatgtt
gctcctggaattgcacttgatgcgcgcaagtttgcaagcgacgcggaaaatcgctttgat
gcatacgcagaagaaattcttgctcaagttgaagcagcaaaactcgagtatccgcttttt
gtaaagccaagccgcgcaggatctagctttggagttacaaaagttgaatcgcgcgatgct
aaagccttagcagaagctatttttgaggcttcagagcacgattggcgagtgttagtagag
cagggaattgacgctcgagaaattgagtgcgcggttcttgcagctcgcgacggcgaagaa
ccgaaagcaagctggcctggagaagttgtgctagacaagcgcgaggctggtgaagaccag
ttctacgattttgacagcaaatacatggattccgcagcttcgcacgttgaagttccagca
aacttgccagcggaaactttagagcgcgttcgcaaaacggcgcttgcagcgttcaaagcg
gcagatgggcggggactaagtcgcgtagattcttttgtaactaaagatggtcgcgtaatt
cttaacgaaatcaacacgatgcctggatttacgccaatctccatgtatccaaaagcttgg
gaagcaactggaataagctacagcgatttaatcacaaagcttattgaaggcgttttgaaa
taa
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