Hipposideros armiger (great roundleaf bat): 109395605
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Entry
109395605 CDS
T04661
Gene name
BRAF
Definition
(RefSeq) B-Raf proto-oncogene, serine/threonine kinase
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
hai
Hipposideros armiger (great roundleaf bat)
Pathway
hai01521
EGFR tyrosine kinase inhibitor resistance
hai01522
Endocrine resistance
hai04010
MAPK signaling pathway
hai04012
ErbB signaling pathway
hai04015
Rap1 signaling pathway
hai04024
cAMP signaling pathway
hai04062
Chemokine signaling pathway
hai04068
FoxO signaling pathway
hai04150
mTOR signaling pathway
hai04270
Vascular smooth muscle contraction
hai04510
Focal adhesion
hai04650
Natural killer cell mediated cytotoxicity
hai04720
Long-term potentiation
hai04722
Neurotrophin signaling pathway
hai04726
Serotonergic synapse
hai04730
Long-term depression
hai04810
Regulation of actin cytoskeleton
hai04910
Insulin signaling pathway
hai04914
Progesterone-mediated oocyte maturation
hai04928
Parathyroid hormone synthesis, secretion and action
hai04934
Cushing syndrome
hai05010
Alzheimer disease
hai05022
Pathways of neurodegeneration - multiple diseases
hai05034
Alcoholism
hai05160
Hepatitis C
hai05161
Hepatitis B
hai05200
Pathways in cancer
hai05205
Proteoglycans in cancer
hai05210
Colorectal cancer
hai05211
Renal cell carcinoma
hai05212
Pancreatic cancer
hai05213
Endometrial cancer
hai05214
Glioma
hai05215
Prostate cancer
hai05216
Thyroid cancer
hai05218
Melanoma
hai05219
Bladder cancer
hai05220
Chronic myeloid leukemia
hai05221
Acute myeloid leukemia
hai05223
Non-small cell lung cancer
hai05224
Breast cancer
hai05225
Hepatocellular carcinoma
hai05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
hai00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
109395605 (BRAF)
04012 ErbB signaling pathway
109395605 (BRAF)
04015 Rap1 signaling pathway
109395605 (BRAF)
04068 FoxO signaling pathway
109395605 (BRAF)
04024 cAMP signaling pathway
109395605 (BRAF)
04150 mTOR signaling pathway
109395605 (BRAF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
109395605 (BRAF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
109395605 (BRAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
109395605 (BRAF)
04062 Chemokine signaling pathway
109395605 (BRAF)
09152 Endocrine system
04910 Insulin signaling pathway
109395605 (BRAF)
04914 Progesterone-mediated oocyte maturation
109395605 (BRAF)
04928 Parathyroid hormone synthesis, secretion and action
109395605 (BRAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
109395605 (BRAF)
09156 Nervous system
04726 Serotonergic synapse
109395605 (BRAF)
04720 Long-term potentiation
109395605 (BRAF)
04730 Long-term depression
109395605 (BRAF)
04722 Neurotrophin signaling pathway
109395605 (BRAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109395605 (BRAF)
05205 Proteoglycans in cancer
109395605 (BRAF)
09162 Cancer: specific types
05210 Colorectal cancer
109395605 (BRAF)
05212 Pancreatic cancer
109395605 (BRAF)
05225 Hepatocellular carcinoma
109395605 (BRAF)
05226 Gastric cancer
109395605 (BRAF)
05214 Glioma
109395605 (BRAF)
05216 Thyroid cancer
109395605 (BRAF)
05221 Acute myeloid leukemia
109395605 (BRAF)
05220 Chronic myeloid leukemia
109395605 (BRAF)
05218 Melanoma
109395605 (BRAF)
05211 Renal cell carcinoma
109395605 (BRAF)
05219 Bladder cancer
109395605 (BRAF)
05215 Prostate cancer
109395605 (BRAF)
05213 Endometrial cancer
109395605 (BRAF)
05224 Breast cancer
109395605 (BRAF)
05223 Non-small cell lung cancer
109395605 (BRAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
109395605 (BRAF)
05022 Pathways of neurodegeneration - multiple diseases
109395605 (BRAF)
09165 Substance dependence
05034 Alcoholism
109395605 (BRAF)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
109395605 (BRAF)
09172 Infectious disease: viral
05161 Hepatitis B
109395605 (BRAF)
05160 Hepatitis C
109395605 (BRAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
109395605 (BRAF)
01522 Endocrine resistance
109395605 (BRAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hai01001
]
109395605 (BRAF)
Enzymes [BR:
hai01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
109395605 (BRAF)
Protein kinases [BR:
hai01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
109395605 (BRAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
C1_2
Pkinase_fungal
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
109395605
NCBI-ProteinID:
XP_019522312
LinkDB
All DBs
Position
Un
AA seq
818 aa
AA seq
DB search
MAALSGGGGGGGGAEQGQALFNGDMEPEAGAGAAASSAADPAIPEEVWNIKQMIKLTQEH
IEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASTDTV
TSSSSSSLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS
LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRK
TFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPI
PQEEASLAETSLTSGSSPSAPPDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRD
RSSSAPNVHINTIEPVNIDEKFPEVELQDQRDLIRDQGFRSDGAPLNQLMRCLRKYQSRT
PSPLLHSVPSEIVFDFEPGPVFRGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSS
SSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTA
PTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFE
MIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQ
FEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMV
GRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSAS
EPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFAAFK
NT seq
2457 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagcggcggcggcggcggcggcggcggcgcggagcagggccaggctctg
ttcaacggggacatggagcccgaggccggcgccggcgccgcggcctcctcggctgcggac
cctgccatcccggaggaggtgtggaacatcaaacaaatgattaagttgacacaggaacat
atagaggccctattggacaaatttggtggagagcataatccaccatcaatatatctggag
gcctatgaagaatacaccagcaagctagatgccctccaacaaagagaacaacagttattg
gaatccctggggaatggaactgatttttctgtttctagctctgcatcaacggacaccgtt
acatcttcttcctcttctagcctttcagtgctaccttcatctctttcagtttttcaaaac
cccacagatgtgtcacggagcaaccctaagtcaccacaaaaacctattgttagagtcttc
ctgcccaacaaacagaggacagtggtacctgcgaggtgtggcgttacagtccgagacagt
ctaaagaaagcactgatgatgagaggtctaatcccagagtgctgtgccgtttacagaatt
caggatggagagaagaagccaattggctgggacactgatatttcctggcttaccggcgag
gagttgcatgtagaagtattggagaatgttccactgacaacacacaactttgtacggaaa
acttttttcaccttagctttttgtgacttttgtcgaaagctgcttttccagggtttccgc
tgtcaaacatgtggttataaatttcaccagcgctgtagcacagaagttcctctgatgtgt
gttaattatgaccaacttgatttgctgtttgtctccaagttctttgaacaccacccaata
ccacaggaggaggcctccttagcagagacttcccttacgtctggatcgtccccttctgca
ccccccgattctattgggccccaaattctcaccagtccgtctccttcaaaatccattcca
attccacagcctttccgaccagcagatgaagatcatcgaaatcagtttggacaacgagac
cggtcctcgtcggctccaaacgtgcatataaacacaatagaacctgtcaatattgatgaa
aaattcccagaagtggaattacaggatcaaagggacttgattagagaccaagggtttcgt
agtgatggagcccctttgaaccagctgatgcgctgtcttcggaaataccaatcccggact
cccagccccctcctccattctgtccccagtgaaatagtgtttgattttgagcctggccca
gtgttcagaggatcaaccacaggtttgtctgccacgccccctgcctcattacctggctca
ctcactaatgtgaaagcactacagaaatctccaggacctcagcgggaaaggaagtcatct
tcatcctcagaagacaggaatcgaatgaaaacacttggtagacgggattcaagtgatgat
tgggagattcctgatggccagatcacagtgggacaaagaattggatccgggtcatttggg
acagtctacaagggaaagtggcatggtgatgtcgcagtgaaaatgttgaatgtgacagca
cccacacctcagcagttacaggccttcaaaaatgaagtaggcgtactcaggaaaactcga
catgtgaatatcctactcttcatgggctattccacaaagccacaactggctattgttaca
cagtggtgtgagggctccagcttatatcaccatctccacatcattgagaccaaatttgag
atgatcaaacttatagatatcgcacggcagactgcacagggcatggattacttacacgcc
aagtcaatcatccacagagacctcaagagtaataatatttttcttcacgaagacctcaca
gtaaaaataggtgattttggtctagccacagtgaaatctcgatggagtgggtcccatcag
tttgaacagttgtctggatccatcttgtggatggcaccagaagtaatcagaatgcaagat
aaaaacccctatagctttcagtcagatgtgtatgcatttgggattgttctgtatgaattg
atgactggacagttaccttattcaaacatcaacaacagggaccagataatttttatggtg
ggacgaggatatctatctccagatctcagtaaggtacgaagtaactgtccaaaagccatg
aagagattaatggcagagtgcctgaaaaagaaaagagatgagagaccactctttccccaa
attctcgcctctattgagctgctggcccgctcattgccaaaaattcaccgcagtgcatca
gaaccctccttgaatcgggctggcttccaaacagaggactttagtctatatgcttgtgct
tctccaaaaacgcccatccaggcggggggatatggagaatttgcagccttcaagtag
DBGET
integrated database retrieval system
