KEGG   Halioglobus maricola: EY643_00235
Entry
EY643_00235       CDS       T06250                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
halc  Halioglobus maricola
Pathway
halc00290  Valine, leucine and isoleucine biosynthesis
halc00620  Pyruvate metabolism
halc01100  Metabolic pathways
halc01110  Biosynthesis of secondary metabolites
halc01210  2-Oxocarboxylic acid metabolism
halc01230  Biosynthesis of amino acids
Module
halc_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:halc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    EY643_00235 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    EY643_00235 (leuA)
Enzymes [BR:halc01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     EY643_00235 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: QFU74200
UniProt: A0A5P9NEQ3
LinkDB
Position
50492..52165
AA seq 557 aa
MSSFDHSKYKPFQAIAKPDRRWPDQRIEAAPLWCSVDLRDGNQALIEPMTARQKSRLWDQ
LVKVGFKEIEVGFPSASSHDFNFVRELIENDRIPEDVTIQVLVQARQELIEKTFEALKGA
RRAVVHVYNSTSTVQREQVFGLDRQGIIDIAVNGAELVQACADKYPETEWVFEYSPESFT
GTEIDFALEVVNAVTAVWQPTPEKPVIINLPATVEMSTPNVYADQIEWFCDNVARRDSLL
ISLHTHNDRGCGVAAAELGVMAGADRVEGTLMGNGERTGNMDVVTMAMNLYSQGVDPKLN
LANMDEIIQTVKECTQLPVHPRHPWAGELVFTAFSGSHQDAIKKCLAQQEGRDHWDVAYL
PIDPADIGRSYQEVIRINSQSGKGGIAYVLQRDYGYEIPRWLSVDFSGSVQAHAEESEAE
VGPEAIFDLFQKTYLNGEGRWQLGNYTVSREDHVDKLQAELSREGVQQQITGTGNGVVAS
FVNAMEAFTGKQIVLVEYSEHALSQSADAEAVCYIQLNIEGDRYCGVGRSHDIVQASLDG
ILRAINKSADRDAEAAA
NT seq 1674 nt   +upstreamnt  +downstreamnt
atgagcagtttcgaccacagcaagtacaagccttttcaagcgattgccaagcccgaccgc
cgctggcctgaccagcgtattgaagctgccccactgtggtgcagtgtcgatctgcgcgat
ggcaaccaggctttgatcgaacccatgacagcgcgccagaagtcgcgtttgtgggaccag
ctggtaaaggtggggttcaaggaaatcgaggtgggattcccctccgcgtccagtcatgac
ttcaactttgtgcgcgagctgatcgaaaacgaccgtattcccgaggatgtcaccatccag
gtgctggtgcaggctcgacaggagctgatcgaaaagacgtttgaggccctcaaaggtgcc
cgccgcgccgtggtccatgtctacaactccacttccacagtgcagcgcgagcaggtcttc
gggctggatcgccagggaattattgatatagcggtcaacggggcggaattggtccaggcc
tgcgccgataaataccctgaaactgagtgggtctttgagtactctccggagagctttact
ggtactgagatcgacttcgccctggaggttgtcaatgccgtaaccgcggtgtggcagccc
acgccggagaagccggtcattatcaacttgcctgccaccgtggagatgagcacaccgaac
gtctacgccgatcagattgagtggttttgtgacaatgtcgcccgccgcgatagcctgctg
atttctctgcacacccacaatgaccggggctgtggtgtcgcggctgccgagctcggtgtg
atggccggggcggaccgggtcgaaggcaccctgatgggcaatggtgagcgcaccggtaat
atggatgtggtcacgatggctatgaacctgtacagccagggcgtcgatccaaaactgaat
ctcgccaatatggacgagatcatccagaccgtgaaggagtgcacccagttgccggtgcac
cctcgtcacccctgggcgggagaactggtgttcactgcgttctccggcagtcaccaggac
gcgatcaagaaatgcctggcgcagcaagaaggccgcgatcattgggacgtggcctacctg
ccgatcgacccggcggacatcgggcgctcttatcaggaagtgatccgtatcaacagccaa
tccggcaagggcggcatcgcctatgtattgcagcgtgactacggttatgaaataccccgc
tggctgtcggtggacttctccggttcagtgcaggcgcatgccgaagagtcggaggcggaa
gtcggccctgaagcgattttcgatttgttccagaaaacttatctgaacggcgagggccgc
tggcaattgggcaactacacagtgagtcgtgaggaccatgtcgacaagttgcaggctgaa
ctgagccgggaaggggtgcagcagcagatcaccggtacagggaacggcgttgtcgcgtca
ttcgttaatgcgatggaggcattcaccggcaaacagattgtgctggtcgaatattccgag
catgcgctcagccagagtgcagatgcggaagcggtgtgctacatccagctgaatattgaa
ggcgatcgctactgcggcgttggtcgtagccacgacattgtgcaggcttcattggacggc
attctgcgcgcgatcaacaaatctgctgaccgtgacgcggaagctgcagcctga

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