Halioglobus maricola: EY643_00235
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Entry
EY643_00235 CDS
T06250
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
halc
Halioglobus maricola
Pathway
halc00290
Valine, leucine and isoleucine biosynthesis
halc00620
Pyruvate metabolism
halc01100
Metabolic pathways
halc01110
Biosynthesis of secondary metabolites
halc01210
2-Oxocarboxylic acid metabolism
halc01230
Biosynthesis of amino acids
Module
halc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
halc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
EY643_00235 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
EY643_00235 (leuA)
Enzymes [BR:
halc01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
EY643_00235 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
QFU74200
UniProt:
A0A5P9NEQ3
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Position
50492..52165
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AA seq
557 aa
AA seq
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MSSFDHSKYKPFQAIAKPDRRWPDQRIEAAPLWCSVDLRDGNQALIEPMTARQKSRLWDQ
LVKVGFKEIEVGFPSASSHDFNFVRELIENDRIPEDVTIQVLVQARQELIEKTFEALKGA
RRAVVHVYNSTSTVQREQVFGLDRQGIIDIAVNGAELVQACADKYPETEWVFEYSPESFT
GTEIDFALEVVNAVTAVWQPTPEKPVIINLPATVEMSTPNVYADQIEWFCDNVARRDSLL
ISLHTHNDRGCGVAAAELGVMAGADRVEGTLMGNGERTGNMDVVTMAMNLYSQGVDPKLN
LANMDEIIQTVKECTQLPVHPRHPWAGELVFTAFSGSHQDAIKKCLAQQEGRDHWDVAYL
PIDPADIGRSYQEVIRINSQSGKGGIAYVLQRDYGYEIPRWLSVDFSGSVQAHAEESEAE
VGPEAIFDLFQKTYLNGEGRWQLGNYTVSREDHVDKLQAELSREGVQQQITGTGNGVVAS
FVNAMEAFTGKQIVLVEYSEHALSQSADAEAVCYIQLNIEGDRYCGVGRSHDIVQASLDG
ILRAINKSADRDAEAAA
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atgagcagtttcgaccacagcaagtacaagccttttcaagcgattgccaagcccgaccgc
cgctggcctgaccagcgtattgaagctgccccactgtggtgcagtgtcgatctgcgcgat
ggcaaccaggctttgatcgaacccatgacagcgcgccagaagtcgcgtttgtgggaccag
ctggtaaaggtggggttcaaggaaatcgaggtgggattcccctccgcgtccagtcatgac
ttcaactttgtgcgcgagctgatcgaaaacgaccgtattcccgaggatgtcaccatccag
gtgctggtgcaggctcgacaggagctgatcgaaaagacgtttgaggccctcaaaggtgcc
cgccgcgccgtggtccatgtctacaactccacttccacagtgcagcgcgagcaggtcttc
gggctggatcgccagggaattattgatatagcggtcaacggggcggaattggtccaggcc
tgcgccgataaataccctgaaactgagtgggtctttgagtactctccggagagctttact
ggtactgagatcgacttcgccctggaggttgtcaatgccgtaaccgcggtgtggcagccc
acgccggagaagccggtcattatcaacttgcctgccaccgtggagatgagcacaccgaac
gtctacgccgatcagattgagtggttttgtgacaatgtcgcccgccgcgatagcctgctg
atttctctgcacacccacaatgaccggggctgtggtgtcgcggctgccgagctcggtgtg
atggccggggcggaccgggtcgaaggcaccctgatgggcaatggtgagcgcaccggtaat
atggatgtggtcacgatggctatgaacctgtacagccagggcgtcgatccaaaactgaat
ctcgccaatatggacgagatcatccagaccgtgaaggagtgcacccagttgccggtgcac
cctcgtcacccctgggcgggagaactggtgttcactgcgttctccggcagtcaccaggac
gcgatcaagaaatgcctggcgcagcaagaaggccgcgatcattgggacgtggcctacctg
ccgatcgacccggcggacatcgggcgctcttatcaggaagtgatccgtatcaacagccaa
tccggcaagggcggcatcgcctatgtattgcagcgtgactacggttatgaaataccccgc
tggctgtcggtggacttctccggttcagtgcaggcgcatgccgaagagtcggaggcggaa
gtcggccctgaagcgattttcgatttgttccagaaaacttatctgaacggcgagggccgc
tggcaattgggcaactacacagtgagtcgtgaggaccatgtcgacaagttgcaggctgaa
ctgagccgggaaggggtgcagcagcagatcaccggtacagggaacggcgttgtcgcgtca
ttcgttaatgcgatggaggcattcaccggcaaacagattgtgctggtcgaatattccgag
catgcgctcagccagagtgcagatgcggaagcggtgtgctacatccagctgaatattgaa
ggcgatcgctactgcggcgttggtcgtagccacgacattgtgcaggcttcattggacggc
attctgcgcgcgatcaacaaatctgctgaccgtgacgcggaagctgcagcctga
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