KEGG   Hippocampus comes (tiger tail seahorse): 109527351
Entry
109527351         CDS       T04969                                 

Gene name
tsc2
Definition
(RefSeq) tuberin isoform X1
  KO
K07207  tuberous sclerosis 2
Organism
hcq  Hippocampus comes (tiger tail seahorse)
Pathway
hcq04115  p53 signaling pathway
hcq04140  Autophagy - animal
hcq04150  mTOR signaling pathway
hcq04218  Cellular senescence
hcq04910  Insulin signaling pathway
hcq05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:hcq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    109527351 (tsc2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    109527351 (tsc2)
  09143 Cell growth and death
   04115 p53 signaling pathway
    109527351 (tsc2)
   04218 Cellular senescence
    109527351 (tsc2)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    109527351 (tsc2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    109527351 (tsc2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hcq01009]
    109527351 (tsc2)
Protein phosphatases and associated proteins [BR:hcq01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     109527351 (tsc2)
SSDB
Motif
Pfam: Tuberin DUF3384 Rap_GAP
Other DBs
NCBI-GeneID: 109527351
NCBI-ProteinID: XP_019744781
LinkDB
Position
Unknown
AA seq 1891 aa
MNKQPSKESLKDKVKGIFGLGPPRPPSKQSDHKPSEFIITTEIIKELHPECGLSNRIRTM
NHICELAKTKRFEEHAVEAVWKSVEDMLTQEQPPEARHAVLQLLRAIIQGQGEHLGALRA
YFFKVIQDYQPCNEDLSDRLEVFKALTENGKDITYLEEDIARFVLLWMDIGLTSDFLHVL
VNLVKFNSCYLDQNVSIMVQKICFLCTRTTSSTDIEVALQVLDAVVCYNCLPSDSLCVFI
VTLCHTVNVKEFCESCWKLMRKVLGTHLGHSAIYRMCRIMEERVYMEDAPLLRGAVFFVG
MALWGAHRLPSLKNTPTLVLPSFYKAMSCANEVVSYEIVLSITRLIKKYGKELQVVTWDI
LLGIIERLLQQIQAIGSPELKAIVYELLTTVEELYEQNGYHGSTEKFFALVEKCADKRPD
ASVLTLISYRAQSIQPAKDGWIQSLHRLMEKFFRNESRSVIRIKVLHILSFVLSTNRQLY
EDELIEMVVIPQLSGIADDRDLAVRKQATQLLVDLAEGCNTHHFTSLLDIIERVASRPLV
CSGPVDVSEREHATESPMEDVKTAILGLLEILQSKLYSLPATHATRVYEMLISHLHLHYK
NKYCSAIASSIRLQVFDFFLMMRADSLHRVGVPNKDGAMRFSPYCYCDIGEPEKRANEKK
PPGPTSPPASGAPPSTAPPLPVTAPIRFAYLPYSPAFSVLLQCLKMETDWKVVKLVLEKL
PWTLQYKVLLLTSPCSLDHLCSTLCCMVTDRLISERLKKTPEGFSRTDVQLAVVPVLTAI
TSYHTYLEQSRQRELVQCLETGLIYRCAKQCVVALTMCTVEMPDIMIKLLPALIVKLTHI
SATVAMASPMLEFLSTLVRLPHLYANFVAEQYVSVFAISLPYTNPSKFNQYIVSLAHHVI
AMWFIRCRLAFRKDFVQYITKGLRSNALLPFDDGHEQSSFRARSTSLNERPKSLRAAKVA
KAAAVVANSSSSPVKELRDLSAMDAFRSRSISVSDHAVRRMQTSTTTCSLGSADENAVTL
ADEGLKTVHLELTETCLDMMARYVFSNFSALPKRSPIAEFLFAGGRSMTWLVGNKLVTIT
TSGGVRTQALLGLDVADRLGGGGEMTRSDPSLHTRITKEAPAKLESQSNQQQSRATRIRV
RSMSGGHALRSGPAQSLSPLVSPSEGELAAQLSPSSAPTLDGLSPPSTSATASAPPPLKD
NRHLAEFVPMLTQGWAEILIRRPSGNTSWLMCLENPPSPFSSELGNMPLQELSTVLMAME
GVKEPPPQTASAPASTATPAPAEPSSQTHSNAGGKPHLIQRSNTVSGSLWFLGQGCAPLG
PQAPIRLYRSISWADSAVVPEEGAGVTTAHTPTDWLESEEFEPMPSDPIFISADKFSKAP
LAGTLSRSSSTSSQEDEKSTLEEVSEGAIPIDQPTQGLSTPGSQELLFQGTNQSQGHGLN
KSSSSPELQTLSEAFSKVTLESETALGDAAQTRGPSEAKAQPPAERESAGGDLNGFTTQT
QMVEGSSSSGPPQSGAARMKLEFPPSGAQPGPISPSGGHRPRGHTISVSAPSSRRERRTE
RDSYHSRPGPSNTEKTSGLCPSFVFLQLYHSPFFGNEANKPLLLPKTQVIDRAVKVLDQM
PPYDTHKIGVIFVGAGQVNNEVAILSNEYGSNRYAAFLTGLGKLIHLKDCDPDQIFLGGL
DQYGDDGEFTYCWHDDIMQAIFHIATLMPNRESDKGCCNKKRHIGNDFVMVVYNDSGEEY
KLGTIKGQFNFVEVIIKPLDYKCNLVSLQCRKDLEGLVDTSVAKIVSDSNLPLLVRQMAL
HANMASLVHQYRANPSDAYASKWLARLRHIKRIRTRAHEDIQSRSTPGISLTQGHAQQNK
PFQQSTAAANPESSGQRKRLVSTVDDFTDFV
NT seq 5676 nt   +upstreamnt  +downstreamnt
atgaataaacaaccaagcaaagaaagcttaaaagacaaggtgaaggggatatttgggctc
ggacccccacgtcctcccagcaagcagagtgaccacaaaccgtctgagtttatcattaca
actgaaatcatcaaggagctccaccctgaatgcggcctaagtaaccgcattcgcacaatg
aatcatatttgtgagcttgccaaaaccaaaagatttgaagagcatgcggtggaggcagtg
tggaaatctgtagaggacatgctgacacaggaacagcctcccgaggcccggcatgctgtc
cttcagctgctcagggccattatccagggacagggtgagcacctcggggccctgagagct
tactttttcaaggtgatccaagactaccaaccatgcaacgaagatctttccgatagactg
gaggtcttcaaggccttaactgaaaacgggaaggacatcacataccttgaggaggacata
gctcgctttgtcctgttgtggatggacatcggtctcacctctgactttcttcatgttctt
gtcaatctggtgaaattcaacagctgttacttggaccaaaatgtctccatcatggtccag
aaaatctgttttctctgcaccagaacgacctcgtcaacagatattgaggttgctctccaa
gttcttgatgcagtggtgtgttacaactgtctcccctcagactctctttgtgtcttcatc
gtcacactgtgccatacagtcaatgtcaaggagttctgtgaatcctgctggaagttgatg
aggaaagtgctgggcactcaccttggccacagtgctatttacagaatgtgccgcataatg
gaagaaagggtgtacatggaagatgcaccattattgagaggagctgtgttctttgttgga
atggcactgtggggagcacacaggctgccttcccttaaaaacacccccacattggttctg
ccttctttttacaaggccatgtcgtgtgccaacgaggtagtatcctatgaaatcgtcctc
tctatcacccgtctgatcaagaaatacggcaaggagctgcaagttgttacttgggacatt
ctgctgggcatcatagagcggcttttgcagcagattcaggctataggcagtcctgaactg
aaggccatcgtatacgagctgttgacaacagtagaagagctttatgagcagaatggttac
catggttccacagagaagttcttcgcgctagtggagaagtgtgccgacaaaagaccggat
gcctcggtgctgaccctcatctcgtacagggcccagtccattcagcccgccaaggatggc
tggattcagagccttcaccgactgatggagaaattcttcagaaatgagagccgcagcgtg
atcaggatcaaagtgcttcacatcctgtcttttgttttaagcaccaaccgccaactgtat
gaggatgagttgatagaaatggtagtgatccctcagcttagtggaatcgctgacgaccga
gacctggccgtacgaaaacaagcgacccagcttttggtggacttggctgagggctgtaac
actcaccacttcactagcctgttggacattattgagcgggttgccagccgacctctggtg
tgttcaggccctgtggatgtttcggagagggagcacgcaacggagtctccaatggaggac
gtcaagactgcgatattgggactacttgagattctgcagagcaaactttacagtctacca
gccacccacgccactcgtgtttatgaaatgcttatcagccacctgcacctccactacaag
aacaagtactgttctgcaattgcgtcaagtatcagactgcaggtctttgacttcttcttg
atgatgcgagcagactctctccatcgcgttggtgttcccaacaaagatggtgccatgagg
ttcagcccttattgctactgtgatataggagagccagaaaaaagagcaaacgagaagaag
cctccaggtccaacgtccccccctgccagcggcgctcctccttccacagctcctcctctt
cctgtcactgcaccgatacgctttgcctacctgccctactcacctgctttcagtgttctc
ctgcagtgcctcaagatggaaacagattggaaggtggtgaaattggtcttggagaagttg
ccgtggacgctgcagtacaaagttctgctgctaacatcaccttgcagcttagatcacctt
tgttctactctgtgctgcatggtgacagaccggctgatttcagaacgcttgaagaagacc
ccagagggattttcaagaacagatgttcagctggcagtggttcccgtcttaacagcaatc
acctcctaccacacctacctggagcaatcaagacaaagggagttggtccagtgtcttgag
acgggcctcatttaccgctgcgccaagcaatgtgtggtggctctcacaatgtgcacggtg
gagatgcctgacatcatgatcaagctgctacccgctcttattgtcaagctcacccacatc
tctgcaacagttgccatggcatctccaatgcttgagttcctttcaactctggtgcgccta
cctcacctttacgccaactttgtagctgagcaatatgttagcgtgtttgcgatctcgcta
ccctacactaacccgtccaagttcaaccagtacatcgtatctctcgcccaccatgtgatt
gctatgtggtttatccgctgcagacttgccttccgtaaagattttgttcagtatatcaca
aagggtttgcgttccaatgccctgctgccattcgatgatggccacgagcagagttctttt
cgtgcccgaagcacaagcctcaatgaaagacccaaaagtcttcgggcggcaaaagtggcg
aaggcggcagcggtggtagccaatagcagcagctctccagttaaagagctgagggacctg
tcagccatggatgctttccgatcccgcagcatcagtgtctccgatcatgcggtccgcagg
atgcaaacgtccaccaccacctgcagtctgggatccgctgatgaaaatgcagtaactctg
gcagatgaggggctgaaaacagtccacttggaactcactgaaacatgtctggacatgatg
gcacgatatgtcttttccaatttctcagcattgcccaaaagatctccaatcgcagagttc
ctctttgccggaggtcgcagtatgacttggctggtgggcaataagctggtgaccatcacg
accagcggaggggttcgcactcaagcactgctgggcctggacgtggctgatcgactagga
ggaggaggggaaatgaccagatctgatccatcattacacacccgaataactaaagaggca
ccagccaaactcgagtcccaatcgaatcagcaacaaagcagagccacacgcatacgggtc
cgctccatgtcaggtggtcacgctcttcgttctggtcctgcccaaagtctcagccctctt
gtgtcaccttctgagggggagttagctgctcaactgtcaccctcttctgctcccacactg
gatggtctcagtcctccctccacatctgccactgcgtcggcccccccaccacttaaggac
aatcgccacctggctgagtttgtccccatgctcacgcagggctgggctgagatcctcatt
cgaagaccatctggtaacacaagctggttaatgtgtctggagaacccgcccagtcccttc
tcctccgagctgggcaacatgcccctgcaggagctttcgactgtcctgatggcgatggaa
ggtgtgaaggaacctcctccccagactgccagtgctccagctagcacagcgactcctgcg
ccggctgagccctctagccaaacgcacagcaatgctggagggaagcctcacctgatccag
cgctcaaacacagtgagcggctctctctggtttctgggtcagggctgcgctcccctaggc
cctcaagcccctatcaggttgtacaggagcatttcctgggcagactcggcagtggtgccg
gaagaaggcgcaggcgtgacaactgcacacaccccaaccgactggctagaaagcgaggaa
ttcgaacctatgccgtctgatcccatcttcatttctgctgataaattttcaaaagctcca
ctggccggaacacttagtaggtcctcctccacctctagtcaagaggatgaaaagtccact
ttggaggaagtgagtgagggggccatccccattgatcagccaactcaggggctctccacc
cctggcagccaggaactcctcttccagggcaccaaccaatcccagggtcatggactcaat
aagtccagctcctcaccggaacttcagaccttatcagaagccttctccaaagtgactctg
gagtcggagaccgcgctaggagatgcagcccagaccagagggccttccgaagccaaggcc
cagccgcccgctgagcgggagagtgcaggcggagacctcaatggattcacaacacagacg
caaatggtggaaggctcctcctcatcagggcctcctcaaagtggagcggcaagaatgaag
ttggagtttccaccaagtggagcgcagccgggacccatatcccccagcgggggtcacaga
ccacgagggcacaccatctcggtatcggcgccttcttccaggagagagaggaggactgag
agagattcataccacagtcgacctggacccagcaacactgagaagacgtctgggctgtgc
ccgagctttgtgttcctccagctgtaccactcgcctttctttgggaatgaagccaacaag
ccgttgctgctgcccaaaacccaagtaattgatcgtgctgtaaaggttctggatcagatg
cctccttatgacactcataagattggagtgatcttcgttggagcgggtcaggttaacaat
gaggtagccatcctttcaaacgagtatggttcaaaccgctatgctgccttcctgacgggg
ctcgggaaattaatccacttgaaagactgcgaccccgaccagatcttcctgggcgggctt
gatcagtatggagatgatggcgagttcacgtactgctggcatgatgacatcatgcaagct
atcttccatattgcgacactgatgccaaacagggagagcgacaagggctgctgcaataag
aagcgccacattggcaatgattttgtcatggtggtttacaacgattctggtgaagagtac
aaactgggcaccataaagggtcagtttaactttgtggaggtgatcataaaaccactggat
tataaatgtaacctcgtttccctgcagtgccgtaaagacctggagggcttagtcgatacg
tctgtggcaaaaatagtctctgacagcaacctcccgctattggtcagacagatggctctg
catgccaacatggcctccttggtgcatcagtacagagctaacccttcagacgcttatgcc
tccaagtggctggcaaggttacggcacatcaagaggatcaggacaagggctcatgaagac
attcagtcccgatcgactcctggcatctcgctgacgcagggacatgctcagcagaacaag
ccttttcagcagagcaccgcagccgcaaaccccgagagctcaggccagcgtaaaaggctt
gtttcaacggtcgatgacttcactgattttgtgtga

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