KEGG   Heterocephalus glaber (naked mole rat): 101696396Help
Entry
101696396         CDS       T02812                                 

Definition
(RefSeq) glutathione S-transferase P
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101696396
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101696396
   00982 Drug metabolism - cytochrome P450
    101696396
   00983 Drug metabolism - other enzymes
    101696396
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101696396
   05204 Chemical carcinogenesis
    101696396
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101696396
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101696396
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101696396
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101696396
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101696396
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101696396
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_C_3 GST_C GST_N GST_C_2
Motif
Other DBs
NCBI-GeneID: 101696396
NCBI-ProteinID: XP_012930494
UniProt: A0A0N8ESH7
LinkDB All DBs
Position
Un
AA seq 210 aa AA seqDB search
MAPYTIVYFPVRGRCEAIRMLLADQGQSWKEEVVTMESWMQGQLRASCLYGQLPKFQDGD
LTLYQSNAILRHLGRSLGLYGKDQREAALVDMVNDGVEDLRCKYVTFIYTNYEAGKNEYV
KALPGHLKPFETLLSKNQGGKAFIVGDQISFADYNLLGLLLNHQVLAPGCLDAFPLLSAY
VARLSARPKLKAFLASPDHVNRPINGNGKQ
NT seq 633 nt NT seq  +upstreamnt  +downstreamnt
atggctccctacaccattgtctacttcccagttcgagggcgctgtgaggccattcgcatg
ctgctggctgaccagggccagagctggaaggaggaggtggtgaccatggagtcctggatg
cagggccagctcagggcttcctgtctgtatgggcagctccccaagttccaggacggagac
ctcaccctgtaccagtctaatgccatcctgcgccacctgggccgttcccttgggctctac
gggaaggaccagcgggaagcagccctggtggacatggtgaatgacggtgtggaggacctc
cgctgcaaatatgttaccttcatctacaccaactacgaggcaggcaagaatgaatatgtg
aaggcactgcctgggcatctgaaacctttcgagactctgctgtccaagaaccaggggggc
aaggctttcattgtgggtgaccagatctccttcgctgactacaacctgctggggttgctg
ctgaaccaccaggttctggcccctggctgcctggatgctttccccctgctctcggcctat
gtggcacgcctcagtgccaggcccaaactcaaggccttcctggcctccccagatcacgtg
aaccggcccatcaatggaaatggcaaacagtga

KEGG   Heterocephalus glaber (naked mole rat): 101703755Help
Entry
101703755         CDS       T02812                                 

Definition
(RefSeq) glutathione S-transferase Mu 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101703755
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101703755
   00982 Drug metabolism - cytochrome P450
    101703755
   00983 Drug metabolism - other enzymes
    101703755
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101703755
   05204 Chemical carcinogenesis
    101703755
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101703755
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101703755
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101703755
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101703755
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101703755
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101703755
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_C GST_C_3 GST_N GST_C_6 GST_N_3
Motif
Other DBs
NCBI-GeneID: 101703755
NCBI-ProteinID: XP_004854560
LinkDB All DBs
Position
Un
AA seq 188 aa AA seqDB search
VIGTSAGYDRSQWLNEKFKLGLDFPNLPYLIDGTHKLTQSNAIMHYIARKHNLCGETEEE
RIHVDIWENQLMDTCMQLVKVCYSPDFEKKKPEFLEGLPDKMKLFSQFLGEQPWFAGNKI
TIKDFLAYDVLDLHHIFEPKCLDAFPKLKDFISRFEGLKKSSAYMKSSLFLPGLLFLKLA
TWEISRTM
NT seq 567 nt NT seq  +upstreamnt  +downstreamnt
gttattgggacatctgcgggctatgacagaagccagtggctgaatgagaaattcaagctg
ggcctggactttcccaatctgccctacttaattgatgggactcacaagctcacccagagc
aacgctatcatgcactatattgcccgtaaacacaacctgtgtggggagacagaagaggaa
aggattcatgtggacatttgggagaaccagcttatggacacctgcatgcagctcgtcaag
gtctgctacagccctgattttgagaaaaagaagccagagttcttggagggactccctgac
aagatgaagctcttctcacagttcctgggggagcagccttggtttgcagggaacaagatc
accatcaaggatttccttgcttatgatgtccttgacctgcaccatatatttgaacctaag
tgtctggatgcattccccaagctgaaggacttcatatcccgctttgagggtctgaagaag
agctcagcctacatgaagtcgagcctcttccttccaggtcttttgtttctaaaattggcc
acatgggaaataagtaggaccatgtga

KEGG   Heterocephalus glaber (naked mole rat): 101705794Help
Entry
101705794         CDS       T02812                                 

Definition
(RefSeq) glutathione S-transferase B
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101705794
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101705794
   00982 Drug metabolism - cytochrome P450
    101705794
   00983 Drug metabolism - other enzymes
    101705794
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101705794
   05204 Chemical carcinogenesis
    101705794
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101705794
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101705794
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101705794
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101705794
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101705794
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101705794
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_C GST_C_3 GST_N GST_C_6 GST_C_2 GST_N_3
Motif
Other DBs
NCBI-GeneID: 101705794
NCBI-ProteinID: XP_004853707
LinkDB All DBs
Position
Un
AA seq 220 aa AA seqDB search
MPMILGYWDLRGISHPIRLILEYTNSSYEEKRYTMGGGNAPDYDRSQWLNEKFKLGLDFP
NLPYLIDGTHKVTQSNAILRYIARKHNLCGQTEEEKIRVDILENQVMDTRMQLINLSYSP
DFEKKKPEFLEGLPDKMKLFSQFLGKQPWFAGNKITFVDFLAYDILDQHRMFDPKCLEAF
PNLKDFMSRFEGLEKISAYMKSSRFLPRPVFSQSAVWGSK
NT seq 663 nt NT seq  +upstreamnt  +downstreamnt
atgcccatgatactgggttactgggacttgcgcgggatatctcatcccatccgcttgatc
ctggaatacacaaactccagctatgaagagaagagatacaccatggggggcggtaatgct
ccggactatgacagaagccagtggctgaatgagaagttcaagctgggcctggactttccc
aatctgccctacttaattgatgggactcacaaggtcacccagagcaacgccatcctgcgc
tacattgcccgcaagcacaacctgtgtgggcagacagaagaggagaagattcgtgtggac
attttggagaaccaggttatggacacccgcatgcagctcatcaatctctcctacagccct
gattttgagaaaaagaagccagaattcttggagggcctccctgacaagatgaagctcttc
tcacagttcctggggaagcagccttggtttgcagggaacaagatcaccttcgtggatttc
cttgcttatgatatccttgaccagcaccgtatgtttgaccccaagtgcctggaggccttc
cctaacttgaaagacttcatgtcccgctttgagggcctggagaagatctctgcctacatg
aagtccagccgcttccttccaagacctgtgttttcacagagtgcagtgtggggcagcaag
tag

KEGG   Heterocephalus glaber (naked mole rat): 101706734Help
Entry
101706734         CDS       T02812                                 

Gene name
Hpgds
Definition
(RefSeq) hematopoietic prostaglandin D synthase
  KO
K04097  prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00590  Arachidonic acid metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl01100  Metabolic pathways
hgl05204  Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    101706734 (Hpgds)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101706734 (Hpgds)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101706734 (Hpgds)
   00982 Drug metabolism - cytochrome P450
    101706734 (Hpgds)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis
    101706734 (Hpgds)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101706734 (Hpgds)
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.99  Other intramolecular oxidoreductases
    5.3.99.2  prostaglandin-D synthase
     101706734 (Hpgds)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_C_3 GST_N GST_N_3 GST_C GST_C_6 GST_C_2 GST_N_4 GST_N_2
Motif
Other DBs
NCBI-GeneID: 101706734
NCBI-ProteinID: XP_004848142
UniProt: G5BXP7
LinkDB All DBs
Position
Un
AA seq 199 aa AA seqDB search
MPNYKLIYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPEIKSTLPFGKIPILEVDGLK
LHQSLAIARYLTKTTDLAGKTATEQWQVDAMVDTLDDFMSRFPWAEKKQEVKNQIFNELL
TCEAPHLLQDLETYLGDKEWFIGDSVTWADFYWDICSTTLLVFKPGLLNNCPRLQTLRKK
VQAIPAIADWLQRRPQTKL
NT seq 600 nt NT seq  +upstreamnt  +downstreamnt
atgccaaactacaaactgatttattttaatatgagaggaagagcagaaattattcgttac
atatttgcttatttggacataaagtatgaagatcacaggatagaacaagctgactggccg
gaaatcaaatcaactcttccatttggcaaaattcccattttggaagtcgatggacttaag
cttcaccagagcctggcgatagcaagatacctgaccaaaaccacagatttggctggaaag
acagcaacagaacaatggcaagttgatgccatggtggacacactggatgatttcatgtca
cgttttccttgggcagagaaaaagcaagaagtaaaaaatcaaatttttaacgagctgctc
acatgtgaggccccccaccttctgcaagacttggagacatatttaggggacaaagagtgg
tttattggtgactctgtgacttgggcagatttctactgggacatctgcagcaccacactt
ctggtctttaaacctggcttgctgaacaactgccccaggttgcagactttgcgcaagaaa
gtccaagccatccctgccatcgctgactggttacagcggaggccccagaccaaactctag

KEGG   Heterocephalus glaber (naked mole rat): 101707238Help
Entry
101707238         CDS       T02812                                 

Gene name
Gstm2
Definition
(RefSeq) glutathione S-transferase mu 2
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101707238 (Gstm2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101707238 (Gstm2)
   00982 Drug metabolism - cytochrome P450
    101707238 (Gstm2)
   00983 Drug metabolism - other enzymes
    101707238 (Gstm2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101707238 (Gstm2)
   05204 Chemical carcinogenesis
    101707238 (Gstm2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101707238 (Gstm2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101707238 (Gstm2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101707238 (Gstm2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101707238 (Gstm2)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101707238 (Gstm2)
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101707238 (Gstm2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N GST_C GST_C_3 GST_C_6 GST_N_3 GST_C_2
Motif
Other DBs
NCBI-GeneID: 101707238
NCBI-ProteinID: XP_004853711
LinkDB All DBs
Position
Un
AA seq 218 aa AA seqDB search
MSVTLGYWDIRGLAHAIRLLLEYTDTSYEEKRYTMGDAPDYDRSQWLNEKFKLGLDFPNL
PYLIDGTHKLTQSNAIMRYIARKHNLCGETEEEKIRVDILENQLMDTGMQLARLCYNPEF
EKLKPEYLDQLPEMMKLFSQFLGKLPWFAGNKITFVDFLAYDIIEMNRVFEPTCLDAFPN
LKDFISRFEGLKKISAYMKSSRFLPRPVFTKMAIWGNK
NT seq 657 nt NT seq  +upstreamnt  +downstreamnt
atgtccgtgactctaggttactgggacatccgcgggctggctcacgccatccgcctgctc
ctggaatacacagacaccagctatgaggagaagagatacaccatgggggacgctcctgac
tatgacagaagccagtggctaaatgagaagttcaagctgggacttgacttccccaatctg
ccctacttaattgatgggactcacaagctcacccagagcaacgccatcatgcgctacatt
gcccgcaagcacaacctgtgtggggagacagaagaggagaagattcgtgtggacattttg
gagaaccagcttatggacacgggcatgcagctggccaggctttgctacaaccctgagttt
gagaaactgaaaccagaatacttggaccaactccctgaaatgatgaagctcttctcacag
ttcttagggaagctaccatggtttgcagggaacaagatcacttttgtggatttccttgct
tatgatatcattgagatgaaccgagtatttgagcctacatgtctggatgcattcccaaac
ctgaaggacttcatatcccgctttgagggtctaaagaagatctctgcctacatgaagtcc
agccgcttcctcccgagacctgtatttacaaagatggcaatatggggcaacaagtag

KEGG   Heterocephalus glaber (naked mole rat): 101708562Help
Entry
101708562         CDS       T02812                                 

Gene name
Gstm3
Definition
(RefSeq) glutathione S-transferase mu 3
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101708562 (Gstm3)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101708562 (Gstm3)
   00982 Drug metabolism - cytochrome P450
    101708562 (Gstm3)
   00983 Drug metabolism - other enzymes
    101708562 (Gstm3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101708562 (Gstm3)
   05204 Chemical carcinogenesis
    101708562 (Gstm3)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101708562 (Gstm3)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101708562 (Gstm3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101708562 (Gstm3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101708562 (Gstm3)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101708562 (Gstm3)
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101708562 (Gstm3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N GST_C GST_C_3 GST_N_3 GST_C_2 GST_C_6
Motif
Other DBs
NCBI-GeneID: 101708562
NCBI-ProteinID: XP_004853713
LinkDB All DBs
Position
Un
AA seq 225 aa AA seqDB search
MSCSSAMVLGYWDIRGLAHAIRLLLEFTDTAYEEKYYTCGEAPDYDRSQWLDVKFKLNLD
FPNLPYLIDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIMENQIMDFRIQLVRLCY
DSDFEKMKPQYLEQLPGQLKQFSLFLGTYSWFAGEKLTFVDFLAYDVLDQNRIFEPKCLD
EFPNLKDFMCRFEALEKIASYLQSDRFFKMPINNKMAKWGNKCIC
NT seq 678 nt NT seq  +upstreamnt  +downstreamnt
atgtcttgcagttcggctatggttctgggttactgggatattcgcggactggcgcatgcc
atccgcctgctcctggagttcactgatacagcctatgaggagaagtattacacttgcggg
gaagctcctgactatgatcgaagccaatggctggatgtgaaattcaagctaaacctggac
tttcctaatcttccttacctgatagacggcaagaacaaaatcacccagagcaatgccatc
ttgcgctacatcgctcgcaagcacaacatgtgtggtgagactgaggaagaaaagattagg
gtggacataatggaaaatcaaataatggatttccgcatccaactggtgcggctttgctac
gactctgactttgaaaagatgaaacctcagtacttggaacagctacctggacaattaaaa
caattttccttattcctggggacgtactcatggtttgcaggggaaaagctcacctttgtg
gattttctcgcctatgatgtcttagaccagaaccgtatatttgaacccaagtgcctggat
gagttcccaaatctgaaggatttcatgtgccgttttgaggctttggagaaaatagcttcc
tatctgcagtctgaccgcttctttaagatgcctatcaataacaagatggccaagtggggg
aacaagtgtatatgctga

KEGG   Heterocephalus glaber (naked mole rat): 101712139Help
Entry
101712139         CDS       T02812                                 

Gene name
Gsto1
Definition
(RefSeq) glutathione S-transferase omega 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101712139 (Gsto1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101712139 (Gsto1)
   00982 Drug metabolism - cytochrome P450
    101712139 (Gsto1)
   00983 Drug metabolism - other enzymes
    101712139 (Gsto1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101712139 (Gsto1)
   05204 Chemical carcinogenesis
    101712139 (Gsto1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101712139 (Gsto1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101712139 (Gsto1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101712139 (Gsto1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101712139 (Gsto1)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101712139 (Gsto1)
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101712139 (Gsto1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N_3 GST_N_2 GST_N GST_C_3 GST_C_2 GST_C Glutaredoxin
Motif
Other DBs
NCBI-GeneID: 101712139
NCBI-ProteinID: XP_004866561
UniProt: G5C8J3
LinkDB All DBs
Position
Un
AA seq 239 aa AA seqDB search
MAARSLSAGSPPPGPVPAGGLRVYSMRFCPYAQRTLLVLEAKGIGHEVVNINLKSKPEWF
FKKNPLGLVPVLENSQGQLICESVITCEYLDEVYPGKKLLPDDPYEKACQKMTFELFSKV
PSLLFRVFMLQQSKGDYSDIKEELKNELNKLEEVLTKKRTTFLGGSSVSMIDYLIWPWFE
RLEVMELQECVDKTPKLKLWMAAMREDPAVKALLLDRKIYQNFVRLYMENSPEAYDCGL
NT seq 720 nt NT seq  +upstreamnt  +downstreamnt
atggcagctcggagcctctctgcaggcagcccgcccccgggcccggtccccgccggcggg
ctgcgcgtctacagcatgcgcttctgcccgtacgcccagaggacgctgctggtgctggag
gccaaagggatcgggcatgaagtcgtcaacatcaacctgaaaagtaagcccgagtggttc
tttaagaagaatccccttggtctggtgccagtgctggaaaacagccagggccagttgatc
tgtgagtctgtcatcacatgtgaatacctggacgaagtgtatcccgggaagaagctgctg
ccagatgacccttatgagaaagcttgccaaaagatgacctttgagttgttttctaaggtg
ccatctttgttattcagggttttcatgctacagcaaagtaaaggagactactctgacata
aaagaggaattgaagaacgaactgaacaagctagaagaggttctgactaagaagaggaca
accttccttggtggcagttctgtctctatgatcgattacctcatctggccctggtttgaa
cggctggaagtaatggagctccaagagtgtgtggacaaaactccaaaacttaagctctgg
atggcagccatgagggaagatcctgcagttaaagccctcctcttggataggaagatctat
caaaatttcgtcagactttacatggagaacagtcctgaagcctacgactgtgggctctga

KEGG   Heterocephalus glaber (naked mole rat): 101712717Help
Entry
101712717         CDS       T02812                                 

Gene name
Gsto2
Definition
(RefSeq) glutathione S-transferase omega 2
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101712717 (Gsto2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101712717 (Gsto2)
   00982 Drug metabolism - cytochrome P450
    101712717 (Gsto2)
   00983 Drug metabolism - other enzymes
    101712717 (Gsto2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101712717 (Gsto2)
   05204 Chemical carcinogenesis
    101712717 (Gsto2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101712717 (Gsto2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101712717 (Gsto2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101712717 (Gsto2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101712717 (Gsto2)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101712717 (Gsto2)
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101712717 (Gsto2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N_3 GST_N_2 GST_N GST_C_2 Glutaredoxin GST_C_3 GST_C
Motif
Other DBs
NCBI-GeneID: 101712717
NCBI-ProteinID: XP_012921545
LinkDB All DBs
Position
Un
AA seq 209 aa AA seqDB search
MSGDATRTLRKGSCPPGPVPEGLVRDYSMRFCPYSHRTRLVLKAKGIRHEVVNIILQSKP
YWYYRKHPFGXIPVLENSQCQLIYESVGHHLDDTYPGRKLFPYDTYERACQKMLLELFCK
ILGYQNTTFFGGDHITMIDDLFWPWFERLDVYGIADCVDYTPKLXLWMAAMKQDPMVSFV
LLIDKQIFLGFLNLYFQNSPNGFDFGLIC
NT seq 630 nt NT seq  +upstreamnt  +downstreamnt
atgtccggggatgcaaccaggaccttgaggaaaggaagctgtcccccaggcccagtcccc
gaggggctcgtccgagactacagcatgaggttctgcccctactcacacaggaccaggctg
gtcctcaaggccaaaggcatcagacatgaagttgtcaacattatcctgcaaagcaagccc
tactggtactacagaaaacacccttttggctaaattcctgtcctggagaatagtcagtgc
caactgatctatgagtcagtcggtcatcacctggacgacacgtacccgggaaggaagctg
tttccgtatgacacttatgaacgggcatgccaaaagatgttactggagctgttctgtaag
atccttggctatcagaacaccaccttcttcggcggagaccacataaccatgatcgatgac
ctcttctggccctggttcgagcggctggatgtgtacgggatcgcagactgtgtggactac
accccaaagctgtagctctggatggcagccatgaagcaggaccccatggtctccttcgtg
ctgctcatagataagcagattttcttgggcttcttgaatctctatttccaaaacagcccc
aatggctttgattttgggctcatttgctga

KEGG   Heterocephalus glaber (naked mole rat): 101712988Help
Entry
101712988         CDS       T02812                                 

Gene name
Gstp1
Definition
(RefSeq) glutathione S-transferase P
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101712988 (Gstp1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101712988 (Gstp1)
   00982 Drug metabolism - cytochrome P450
    101712988 (Gstp1)
   00983 Drug metabolism - other enzymes
    101712988 (Gstp1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101712988 (Gstp1)
   05204 Chemical carcinogenesis
    101712988 (Gstp1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101712988 (Gstp1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101712988 (Gstp1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101712988 (Gstp1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101712988 (Gstp1)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101712988 (Gstp1)
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101712988 (Gstp1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_C_3 GST_C GST_N
Motif
Other DBs
NCBI-GeneID: 101712988
NCBI-ProteinID: XP_004852687
LinkDB All DBs
Position
Un
AA seq 216 aa AA seqDB search
MARQQGRVPPYTIVYFLSRGHCEAMRMLLADQGQSWKEEVVTLETWGRGPLKASCLFEQL
PKFQDRDLALYQSNAILCYLDRSFGLYSKDQQEAALVDMVNDGVEDLIRCCSHLLHNYEK
GKAQCAQELPGDLKPFEFLLAQNKGGQGFIVGEQISFANYNLLDLLLNHQVLAPGCLDAF
PLLLAYMMCLSAWPKLKAFLASSYHVNWPIFSLIKI
NT seq 651 nt NT seq  +upstreamnt  +downstreamnt
atggccagacaacaggggagggtgccgccttacaccattgtctacttcctctccaggggg
cactgtgaggccatgcgcatgctgctggctgaccagggccagagctggaaggaggaggtg
gtgaccttggagacctggggccgaggtccgctgaaggcctcctgtttatttgagcagctc
cccaagttccaggacagagaccttgccctataccagtccaatgccatcctgtgctacctg
gaccgctcctttgggctctatagcaaagaccagcaggaggctgcccttgtggacatggtg
aatgatggggtggaggacctcatcaggtgctgtagccacctcctccataactatgagaag
ggcaaagcccagtgtgcacaggagcttccaggggatctgaaaccttttgaatttttgctg
gcccagaacaagggaggacagggctttatcgtgggggaacagatctccttcgctaactac
aacctgctggacttgctgctgaaccaccaggtcctggctcctggctgcctggatgctttc
cccctgctcttggcctacatgatgtgccttagtgcttggcccaagctcaaggcattcctg
gcctcctcataccatgtgaactggcccatcttttctcttatcaagatatga

KEGG   Heterocephalus glaber (naked mole rat): 101713569Help
Entry
101713569         CDS       T02812                                 

Gene name
Mgst1
Definition
(RefSeq) microsomal glutathione S-transferase 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101713569 (Mgst1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101713569 (Mgst1)
   00982 Drug metabolism - cytochrome P450
    101713569 (Mgst1)
   00983 Drug metabolism - other enzymes
    101713569 (Mgst1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101713569 (Mgst1)
   05204 Chemical carcinogenesis
    101713569 (Mgst1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101713569 (Mgst1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101713569 (Mgst1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101713569 (Mgst1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101713569 (Mgst1)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101713569 (Mgst1)
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101713569 (Mgst1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MAPEG GCP5-Mod21
Motif
Other DBs
NCBI-GeneID: 101713569
NCBI-ProteinID: XP_004845872
UniProt: G5BV57
LinkDB All DBs
Position
Un
AA seq 152 aa AA seqDB search
MADLMDNKVLMAFASYATIVVSKMMFMSTATAFFRITKKVFANPEDCASFGKGENAKKYL
RTDESVERVRRAHLNDLENIVPFLGIGLLYSLSGPDLSTALLHFRIFVGARIYHTIAYLL
PLPQPNRGLAFFAGYGVTLSMAYSLLRNKLYL
NT seq 459 nt NT seq  +upstreamnt  +downstreamnt
atggctgatctgatggataataaagttctcatggcctttgcctcctatgcaacaattgtt
gtttcaaagatgatgtttatgagtactgcaactgcattctttagaataacgaaaaaggtt
tttgccaacccagaagactgtgcaagctttggcaaaggagagaatgccaagaaatatctt
cgaacagatgagagtgtggagcgcgtacgaagagcccacctgaatgatctggaaaatatt
gtgccatttcttggtattggccttctgtattccctgagtggtccagatctctccacagct
ctcctgcacttcagaatctttgtcggagcacggatctaccacaccatagcttatctgctg
ccccttccccagccaaacaggggcctggccttttttgctggatatggagttactctttca
atggcttacagcttgctgaggaacaaattgtatctgtaa

KEGG   Heterocephalus glaber (naked mole rat): 101713648Help
Entry
101713648         CDS       T02812                                 

Gene name
Gstk1
Definition
(RefSeq) glutathione S-transferase kappa 1
  KO
K13299  glutathione S-transferase kappa 1 [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl01100  Metabolic pathways
hgl04146  Peroxisome
hgl05204  Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101713648 (Gstk1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101713648 (Gstk1)
   00982 Drug metabolism - cytochrome P450
    101713648 (Gstk1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    101713648 (Gstk1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis
    101713648 (Gstk1)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101713648 (Gstk1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DSBA Helicase_C_3
Motif
Other DBs
NCBI-GeneID: 101713648
NCBI-ProteinID: XP_004860560
UniProt: G5C2L7
LinkDB All DBs
Position
Un
AA seq 226 aa AA seqDB search
MGPSPRTLELFYDVLSPYSWLGFEVLCRYRNIWNIKLQFRPTYIAGIMKDSGNKPPAMVP
RKAQYMANDLRRLKEHFQVPLRFPKDFNSAVLEKGSLSAMRFLTAVNMEHPESLEKVSRE
LWMRIWSQDEDIVESQSILAAAQKAGLSAEKAQGLLEKSSTAQVKNQLKETTEAACKYGA
FGLPITVVHVDRQTHMLFGSDRMELLAYLLGEKWMGPVPPTLNAKL
NT seq 681 nt NT seq  +upstreamnt  +downstreamnt
atggggccctcgccacgcaccctggagctcttctatgatgtgctatccccctactcctgg
ctgggcttcgaggtcctgtgcaggtatcggaacatctggaacatcaagctgcagtttcgg
cccacctatattgcagggatcatgaaagacagcggaaacaagccaccagctatggttcct
cgaaaagctcagtacatggcaaatgaccttagacgcctgaaagagcatttccaggtcccc
ctcagatttcccaaggatttcaactctgcggttctcgaaaaaggaagtttgtctgccatg
cggttcctcactgccgtgaacatggaacaccccgagagcctggaaaaggtgtccagggag
ctatggatgcgcatctggtcacaggatgaagacatcgtggagtcccagagcatcctggct
gcagcgcagaaggctggtttatctgcagagaaagcccaaggccttctggagaagagctcc
acagcacaagtgaagaatcagctcaaggagaccactgaggcagcctgcaaatatggggcc
ttcgggttgcccatcactgtggtccacgtggatcgccagacgcacatgttatttggctct
gaccgaatggaattgctagcgtacttgctaggagagaagtggatgggccctgtgcctccc
accctgaatgccaaactttag

KEGG   Heterocephalus glaber (naked mole rat): 101714128Help
Entry
101714128         CDS       T02812                                 

Gene name
Gstt2
Definition
(RefSeq) glutathione S-transferase theta-2
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101714128 (Gstt2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101714128 (Gstt2)
   00982 Drug metabolism - cytochrome P450
    101714128 (Gstt2)
   00983 Drug metabolism - other enzymes
    101714128 (Gstt2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101714128 (Gstt2)
   05204 Chemical carcinogenesis
    101714128 (Gstt2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101714128 (Gstt2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101714128 (Gstt2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101714128 (Gstt2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101714128 (Gstt2)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101714128 (Gstt2)
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101714128 (Gstt2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N GST_N_3 GST_N_2 GST_C GST_C_3
Motif
Other DBs
NCBI-GeneID: 101714128
NCBI-ProteinID: XP_004921134
LinkDB All DBs
Position
Un
AA seq 303 aa AA seqDB search
MRGASAREPPPETPPTPGAPALEAAGKDGATVPAEILVTVACGNRLLTDQCEAVGPVISP
VRVIGGELYLDLLSQPCRAIYLFAEKNGIPFQLRTVDLLXGQHLNKKFFQVNSLQKVPVL
KDGDFLLTESSAILIYQSYKCQVADHWYPPDLQASARIHEYLGWHADNILDTFGVTLWTW
MITPLMGTQVPEEKIEXNKTSVAWALQHXEEKFLGNKAFLMGQQVTLADLMSLEEMMQPM
GGDHNVFLSSSKLVEWRMRVELYIGSGLFWEAHDRLVKLAEWDVSTLDPVVKERICKFLE
TYK
NT seq 912 nt NT seq  +upstreamnt  +downstreamnt
atgcgaggggcgagtgcgagggagccccctccggaaaccccgcccacccccggagcgccg
gccctagaggctgcaggcaaagatggagccacggtgcccgcagagatcctggtcacagtg
gcctgtggtaaccgcctcctaactgaccaatgcgaggctgttggtccggtcatcagcccc
gtccgagtcataggcggggagctctacctggacctgctgtcccagccctgccgcgccatc
tacctcttcgccgagaagaatggcatccccttccagctgcgaaccgtggatctgctctaa
ggacagcatttgaacaagaagttcttccaagttaacagcctgcagaaggtgcctgtcctc
aaagacggggacttcctcctgaccgaaagctcagccatcctgatttaccagagttataag
tgccaggtggcagaccactggtacccacctgacctgcaggcctctgcccgaatccatgag
tacctgggctggcatgctgacaacatccttgacacctttggtgtgaccctgtggacctgg
atgatcacaccactcatggggacccaggtgcctgaggagaagatagaatgaaataagacc
agtgtggcctgggctctgcagcatncggaagagaagttcttggggaacaaggccttcctc
atgggccagcaggtgacgctggctgatctcatgtcactggaggagatgatgcagcccatg
gggggcgatcataatgtcttcctcagcagctccaagctggtggagtggcgcatgcgggtg
gagctgtacatcggctctggcctcttctgggaggcccatgaccggttggtgaagttagca
gagtgggatgtctcgacattggatccagtggtcaaggagaggatctgcaaatttctggag
acttacaagtga

KEGG   Heterocephalus glaber (naked mole rat): 101714626Help
Entry
101714626         CDS       T02812                                 

Gene name
Gsta4
Definition
(RefSeq) glutathione S-transferase alpha 4
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101714626 (Gsta4)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101714626 (Gsta4)
   00982 Drug metabolism - cytochrome P450
    101714626 (Gsta4)
   00983 Drug metabolism - other enzymes
    101714626 (Gsta4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101714626 (Gsta4)
   05204 Chemical carcinogenesis
    101714626 (Gsta4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101714626 (Gsta4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101714626 (Gsta4)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101714626 (Gsta4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101714626 (Gsta4)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101714626 (Gsta4)
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101714626 (Gsta4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_C_3 GST_C GST_N GST_C_2
Motif
Other DBs
NCBI-GeneID: 101714626
NCBI-ProteinID: XP_012922539
LinkDB All DBs
Position
Un
AA seq 261 aa AA seqDB search
MAARLKLHCPNGRGCMEPVRWVLAAARVEVPCPWAFILGNHLLSQQVPMVEIDGXKLVQT
RSILHNIAEKHQLFSRDFKDRTLYCGLLWHCCYALADYLPSAARPICFIRIDMYVEGTLD
LLELLIMYPFLKSEDQQKEVFHMGQKAIIRYFLVFEKVGGREAQEHSITIPQEYILQVLR
GHGQNFLVGNQLSLADVILLQTILALEEKIPNVLSAFPFLQEYTVKLSNIPTIKRFLEPG
SKKKPSPDDFYVRTVHNIFVP
NT seq 786 nt NT seq  +upstreamnt  +downstreamnt
atggcagcgaggctcaagctgcactgccccaacgggagaggctgcatggagcccgtcaga
tgggtcctggccgccgccagagtagaggtaccctgcccctgggctttcatcctaggtaac
cacctgctctcccaacaagtgcccatggttgaaatcgatgggnataagttggtgcagacc
cgaagcatcctccacaacatagctgaaaagcaccagctcttcagcagggacttcaaggac
agaaccctgtactgtggcctcctttggcactgctgttatgccttggctgattatctacct
tctgcagcacgtcccatctgctttataaggattgacatgtacgtggaggggacgctggat
ctcttggaactgcttatcatgtatcctttcttaaaatcagaggatcaacaaaaggaagtg
tttcacatgggccagaaggctataattagatacttcctagtgtttgaaaaggtgggtggc
agagaagcccaagagcacagcataaccataccacaagagtatatcctacaggttttaagg
ggtcatggacaaaactttcttgttggtaatcagctgagccttgcagacgtgattctactc
caaaccattttggctctggaagagaaaattcctaatgtcctatctgcatttcctttcctc
caggaatacacagtgaaattaagtaatatccctacaattaagagatttcttgaacctgga
agcaagaagaagccttcccctgatgacttctatgtgagaactgtccacaacatctttgtg
ccatga

KEGG   Heterocephalus glaber (naked mole rat): 101714852Help
Entry
101714852         CDS       T02812                                 

Gene name
Gsta1
Definition
(RefSeq) glutathione S-transferase A1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101714852 (Gsta1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101714852 (Gsta1)
   00982 Drug metabolism - cytochrome P450
    101714852 (Gsta1)
   00983 Drug metabolism - other enzymes
    101714852 (Gsta1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101714852 (Gsta1)
   05204 Chemical carcinogenesis
    101714852 (Gsta1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101714852 (Gsta1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101714852 (Gsta1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101714852 (Gsta1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101714852 (Gsta1)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101714852 (Gsta1)
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101714852 (Gsta1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N GST_C_3 GST_C GST_N_3
Motif
Other DBs
NCBI-GeneID: 101714852
NCBI-ProteinID: XP_004869083
UniProt: G5BC72
LinkDB All DBs
Position
Un
AA seq 222 aa AA seqDB search
MAGKPVLHYFNGRGRMESIRWLLAAAGVEFEEKLIKCPEDFEKLKNEGLLMFQQVPMVEM
DGMKLVQSRAILNYIATKYNLYGKDMKERLLIDMYIEGIMDLYEMISHLALTPPDQTDTK
MALIRDKTKNCYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYCVEEVDASLLAAFPL
LQALKTRISNLPNVKKFLQPGSQRKPPTTAKMIEEARKVFKF
NT seq 669 nt NT seq  +upstreamnt  +downstreamnt
atggcagggaagccggtgcttcactacttcaatggacggggcaggatggagtccatccgg
tggctcttggctgcagctggagtagagtttgaagagaagcttataaaatgtccagaagat
tttgaaaagttaaaaaatgaagggcttttgatgttccagcaagtacccatggtggagatg
gatgggatgaagctggtgcagtccagagccattctcaactacattgccaccaaatacaac
ctctatgggaaagatatgaaagagagactcctgattgatatgtacatagaaggcatcatg
gatttatatgaaatgatctcacatctggcactgactcctccagatcaaacagataccaag
atggctttgatcagagacaaaacaaagaattgctacttccctgcctttgaaaaagtgtta
aagagtcatggacaagactaccttgttggcaacaagctgagcagggctgacattcacctg
gttgaacttctctactgtgttgaagaggttgatgcgagtcttttggctgctttccctctg
ctgcaggctctaaaaaccagaatcagtaacctgcccaatgtgaagaagtttctgcagcct
ggcagccagaggaagcctcccactactgcaaaaatgatagaagaagccagaaaggttttc
aagttttag

KEGG   Heterocephalus glaber (naked mole rat): 101716174Help
Entry
101716174         CDS       T02812                                 

Gene name
Mgst2
Definition
(RefSeq) microsomal glutathione S-transferase 2
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101716174 (Mgst2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101716174 (Mgst2)
   00982 Drug metabolism - cytochrome P450
    101716174 (Mgst2)
   00983 Drug metabolism - other enzymes
    101716174 (Mgst2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101716174 (Mgst2)
   05204 Chemical carcinogenesis
    101716174 (Mgst2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101716174 (Mgst2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101716174 (Mgst2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101716174 (Mgst2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101716174 (Mgst2)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101716174 (Mgst2)
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101716174 (Mgst2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MAPEG
Motif
Other DBs
NCBI-GeneID: 101716174
NCBI-ProteinID: XP_004855049
UniProt: A0A0P6J319
LinkDB All DBs
Position
Un
AA seq 147 aa AA seqDB search
MAGNVILLAAISVLSACQQSYFAFQVGRARFKCKVIPPAVTGSLEFERVFRAQQNCVEFY
PVFLITLWMAGWYFNQVFATCLGLVYIYSRHKYFWGYSEAAEKRISGFRLSLGTLGLLGV
LGALGIANSFLDEYLDIHVAKQLRRYF
NT seq 444 nt NT seq  +upstreamnt  +downstreamnt
atggccgggaatgtgattctgctggctgccatctctgtcctctctgcttgtcagcaaagt
tattttgcttttcaggttggaagggcaagattcaaatgcaaggtgatccccccggcagtc
actgggtccctggagtttgaaagagtgtttcgtgcacaacaaaactgtgtggagttttac
cccgtattcctgattacactgtggatggctggatggtatttcaatcaagtttttgctact
tgtctggggctggtgtacatatatagccgtcacaagtacttctggggatattcagaagct
gctgaaaaaaggatcagtggtttccgattgagcctgggaactttgggcttgttgggggtc
ctcggcgccctggggattgcgaacagctttctggatgaatacctggacatccatgttgcc
aagcaactgaggcgatacttctaa

KEGG   Heterocephalus glaber (naked mole rat): 101717166Help
Entry
101717166         CDS       T02812                                 

Gene name
Mgst3
Definition
(RefSeq) microsomal glutathione S-transferase 3
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101717166 (Mgst3)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101717166 (Mgst3)
   00982 Drug metabolism - cytochrome P450
    101717166 (Mgst3)
   00983 Drug metabolism - other enzymes
    101717166 (Mgst3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101717166 (Mgst3)
   05204 Chemical carcinogenesis
    101717166 (Mgst3)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101717166 (Mgst3)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101717166 (Mgst3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101717166 (Mgst3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101717166 (Mgst3)
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101717166 (Mgst3)
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101717166 (Mgst3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MAPEG
Motif
Other DBs
NCBI-GeneID: 101717166
NCBI-ProteinID: XP_004865241
UniProt: G5AQ31
LinkDB All DBs
Position
Un
AA seq 158 aa AA seqDB search
MAVLSKEYGFVILTGAASFVMVLHLAINVNKARKKYKVEYPVMYSTDPENGHLFNCIQRA
HQNTLEVYPPFLFFLAVGGVYHPRIASGLGMAWIVGRVLYAYGYYTGDPRKRYRGSVGSI
ALFALMGTTVCSAFQHLGWVKSGLGGGSKSCHGKITGV
NT seq 477 nt NT seq  +upstreamnt  +downstreamnt
atggccgtcctctcgaaggaatatggtttcgtgatcctgacgggtgctgccagctttgtc
atggtactgcacctcgccatcaatgttaacaaggcccgcaagaagtacaaggtggagtat
cctgtcatgtacagcacagaccctgagaacgggcacctcttcaactgcattcagcgggcc
caccagaacacgttggaagtgtaccccccgttcctgtttttcttagctgttggaggtgtt
taccacccgcgtatagcttctggcttgggcatggcctggattgttggacgagttctttat
gcctatggctactacacgggtgatcccagaaagcggtaccgaggatccgtggggtctatc
gccctctttgccttgatgggcacaactgtgtgctctgctttccagcatcttggctgggtt
aaatctggcttgggcggtggctccaaaagctgccatggaaaaattacaggggtttaa

KEGG   Heterocephalus glaber (naked mole rat): 101719471Help
Entry
101719471         CDS       T02812                                 

Definition
(RefSeq) glutathione S-transferase Mu 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101719471
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101719471
   00982 Drug metabolism - cytochrome P450
    101719471
   00983 Drug metabolism - other enzymes
    101719471
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101719471
   05204 Chemical carcinogenesis
    101719471
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101719471
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101719471
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101719471
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101719471
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101719471
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101719471
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N GST_C_3 GST_C GST_C_6 GST_C_2
Motif
Other DBs
NCBI-GeneID: 101719471
NCBI-ProteinID: XP_004845098
LinkDB All DBs
Position
Un
AA seq 218 aa AA seqDB search
MPMIFGYWDIHGLAHAIPLLLEYTDTSYEEKRYTMGDAPDYDRSQWLNEKFKLGLDFPNL
HYLIDGTHKLTQSNAIMHYIARKHNLCGETEEERIRVDILENQLTNTHMQLVMVCYSPDF
EKKKPEFLEGLPDKMKLFSQFLGEQPWFAGNKITFVDFLAYDVLDLHCIFEPKCLDAFPK
LKVFISHFEGLKKISAYMKSSCFLPDPLFLKKATWGNK
NT seq 657 nt NT seq  +upstreamnt  +downstreamnt
atgcccatgatatttggttattgggacatccacgggctggctcacgccatccccctgctc
ctggaatacacagacaccagctatgaggagaagagatacaccatgggggatgctcccgac
tatgacagaagccagtggctgaatgagaagttcaagctgggcctggactttcccaatctg
cactacttaattgatgggactcacaagctcacccagagcaatgccatcatgcactacatt
gcccgcaaacacaacctgtgtggggagacagaagaggaaaggattcgtgtggacattttg
gagaaccagcttacgaacacccacatgcagctcgtcatggtctgctacagccctgatttt
gagaaaaagaagccagagttcttggaagggctccctgacaagatgaagctcttctcacag
ttcctgggggagcaaccttggtttgcagggaacaagatcaccttcgtggatttccttgct
tatgatgtccttgacctgcactgtatatttgaacccaagtgtctggatgcattccccaag
ctgaaggtcttcatatcccactttgagggcctgaagaagatatcagcctacatgaagtcc
agctgcttccttccagatcctttatttctaaaaaaggccacatggggaaacaagtag

KEGG   Heterocephalus glaber (naked mole rat): 101725364Help
Entry
101725364         CDS       T02812                                 

Definition
(RefSeq) glutathione S-transferase theta-1-like
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101725364
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101725364
   00982 Drug metabolism - cytochrome P450
    101725364
   00983 Drug metabolism - other enzymes
    101725364
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101725364
   05204 Chemical carcinogenesis
    101725364
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101725364
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101725364
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101725364
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101725364
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101725364
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101725364
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N GST_N_3 GST_N_2 GST_C GST_C_2 GST_C_3
Motif
Other DBs
NCBI-GeneID: 101725364
NCBI-ProteinID: XP_004843623
LinkDB All DBs
Position
Un
AA seq 241 aa AA seqDB search
MGLDLYLDLMSQPCRAVYIFAKKNGIPFQLRTVELLKGQHYTDSFAQVNPLRKVPALKDE
DFILAESVAILLYLSHKYKTPDHWYPQDLQARAWVDEYLSWQHTALRSCCTWAMWQKMMF
PVVLHQLVPQETLSYTLAELDSCLQLLETKFLRDQAFLTGPQISVADLMAITELMHPVST
GCQVFECRPKLDAWRRHVEAVVREDLFQEAHTVVLKAKDMPPLPAPTLKEKLLHSVWILL
Q
NT seq 726 nt NT seq  +upstreamnt  +downstreamnt
atgggcctggatctctacctcgaccttatgtcccagccctgccgcgcagtctacatcttt
gccaagaaaaacggcatccctttccagctgcgcacggtggagctgctcaaaggccagcac
tacacagattcctttgctcaggtcaaccccctgaggaaggtgccagccttgaaggatgag
gacttcatcttggctgagagtgtggccattctgctgtatctgagtcacaagtacaagacc
cctgaccactggtacccccaggacctgcaggccagagcctgggtggatgagtacctgtcc
tggcagcacacggccttgcggagttgctgcacttgggccatgtggcagaagatgatgttc
cctgttgtgctgcatcagctggtgccccaggagacattgtcgtacactttggctgagctg
gacagttgcctgcagctgcttgagaccaagttccttcgggatcaggccttcctcactggt
ccccaaatctctgtggctgacttgatggccatcacggaactgatgcatcctgtcagtact
ggctgccaagtctttgaatgccgacccaagttggatgcatggcgccggcatgtggaggct
gtggtgcgggaggacctcttccaggaggcccacacagttgtcctgaaggccaaggacatg
cctcctctaccggcccctaccttgaaggagaaattgctgcactcagtgtggattttgttg
cagtga

KEGG   Heterocephalus glaber (naked mole rat): 101726608Help
Entry
101726608         CDS       T02812                                 

Definition
(RefSeq) glutathione S-transferase theta-1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00480  Glutathione metabolism
hgl00980  Metabolism of xenobiotics by cytochrome P450
hgl00982  Drug metabolism - cytochrome P450
hgl00983  Drug metabolism - other enzymes
hgl01100  Metabolic pathways
hgl01524  Platinum drug resistance
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis
hgl05225  Hepatocellular carcinoma
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101726608
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101726608
   00982 Drug metabolism - cytochrome P450
    101726608
   00983 Drug metabolism - other enzymes
    101726608
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101726608
   05204 Chemical carcinogenesis
    101726608
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101726608
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101726608
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101726608
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hgl02000]
    101726608
Enzymes [BR:hgl01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101726608
Transporters [BR:hgl02000]
 Other Transporters
  Pores ion channels [TC:1]
   101726608
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N GST_N_3 GST_C GST_N_2 GST_C_3 GST_C_2 GST_N_4
Motif
Other DBs
NCBI-GeneID: 101726608
NCBI-ProteinID: XP_004843627
LinkDB All DBs
Position
Un
AA seq 240 aa AA seqDB search
MGLELYLDLLSQPCRAIYIFAKKNGIPFQLRTVDLLKGQHLSDAFVQVNPLKKVPALKDG
DFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTALRRNCLRALWHKVMF
PVFLGEQVSSELLAATLAELDDTLQVFEDKFLQNKAFLIGSQISLADLVAITELMHPIGA
GCQVFEGRPKLAAWHRQVEAAVGENLFQEAHEIILKVKDSPPADPTIKQKVMPGVLAMIR
NT seq 723 nt NT seq  +upstreamnt  +downstreamnt
atgggcctggagctctacctggacctgctgtcccagccctgccgagccatctacatcttc
gccaagaagaacggcatccccttccagctgagaaccgtggatctgctcaagggccagcac
ctcagtgatgctttcgtccaggtgaaccccctgaagaaggtgccagccttgaaagatggg
gacttcaccttgactgagagtgtggccatcctactctacctgacgcgcaagtataaggtt
cctgactactggtaccctcaggacctgcaggcgcgtgcccgtgtggatgagtacctggca
tggcagcacaccgccctgaggagaaactgcctccgggccctctggcacaaggtgatgttc
cctgttttcctgggtgagcaagtatcttctgagctgctggcagccaccttggcagagtta
gatgacaccctgcaggtcttcgaggacaagttcctccagaacaaagctttcctcattgga
tcccaaatctccctggctgacctggtagccatcacggagctgatgcatcccattggtgct
ggctgccaagtctttgaaggccgacccaagctggctgcctggcacaggcaagtggaggct
gcagtaggggagaacctcttccaggaggcccatgaaatcatcctgaaggtgaaggactct
ccacctgctgaccccaccataaagcagaaggtgatgcctggggtgctggccatgatccgg
tga

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