Heterocephalus glaber (naked mole rat): 101698286 Help Entry 101698286         CDS       T02812                                  Gene name Mapk9 Definition (RefSeq) mitogen-activated protein kinase 9   KO K04440   mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl01522   Endocrine resistance hgl04010   MAPK signaling pathway hgl04012   ErbB signaling pathway hgl04014   Ras signaling pathway hgl04024   cAMP signaling pathway hgl04068   FoxO signaling pathway hgl04071   Sphingolipid signaling pathway hgl04137   Mitophagy - animal hgl04140   Autophagy - animal hgl04141   Protein processing in endoplasmic reticulum hgl04210   Apoptosis hgl04215   Apoptosis - multiple species hgl04217   Necroptosis hgl04310   Wnt signaling pathway hgl04380   Osteoclast differentiation hgl04510   Focal adhesion hgl04530   Tight junction hgl04620   Toll-like receptor signaling pathway hgl04621   NOD-like receptor signaling pathway hgl04622   RIG-I-like receptor signaling pathway hgl04625   C-type lectin receptor signaling pathway hgl04657   IL-17 signaling pathway hgl04658   Th1 and Th2 cell differentiation hgl04659   Th17 cell differentiation hgl04660   T cell receptor signaling pathway hgl04664   Fc epsilon RI signaling pathway hgl04668   TNF signaling pathway hgl04722   Neurotrophin signaling pathway hgl04723   Retrograde endocannabinoid signaling hgl04728   Dopaminergic synapse hgl04750   Inflammatory mediator regulation of TRP channels hgl04910   Insulin signaling pathway hgl04912   GnRH signaling pathway hgl04914   Progesterone-mediated oocyte maturation hgl04917   Prolactin signaling pathway hgl04920   Adipocytokine signaling pathway hgl04926   Relaxin signaling pathway hgl04930   Type II diabetes mellitus hgl04931   Insulin resistance hgl04932   Non-alcoholic fatty liver disease hgl04933   AGE-RAGE signaling pathway in diabetic complications hgl04935   Growth hormone synthesis, secretion and action hgl05010   Alzheimer disease hgl05012   Parkinson disease hgl05016   Huntington disease hgl05017   Spinocerebellar ataxia hgl05020   Prion disease hgl05022   Pathways of neurodegeneration - multiple diseases hgl05132   Salmonella infection hgl05133   Pertussis hgl05135   Yersinia infection hgl05142   Chagas disease hgl05145   Toxoplasmosis hgl05152   Tuberculosis hgl05161   Hepatitis B hgl05162   Measles hgl05166   Human T-cell leukemia virus 1 infection hgl05167   Kaposi sarcoma-associated herpesvirus infection hgl05169   Epstein-Barr virus infection hgl05170   Human immunodeficiency virus 1 infection hgl05171   Coronavirus disease - COVID-19 hgl05200   Pathways in cancer hgl05210   Colorectal cancer hgl05212   Pancreatic cancer hgl05231   Choline metabolism in cancer hgl05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:hgl00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     101698286 (Mapk9)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101698286 (Mapk9)    04012 ErbB signaling pathway     101698286 (Mapk9)    04014 Ras signaling pathway     101698286 (Mapk9)    04310 Wnt signaling pathway     101698286 (Mapk9)    04668 TNF signaling pathway     101698286 (Mapk9)    04068 FoxO signaling pathway     101698286 (Mapk9)    04071 Sphingolipid signaling pathway     101698286 (Mapk9)    04024 cAMP signaling pathway     101698286 (Mapk9)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101698286 (Mapk9)    04137 Mitophagy - animal     101698286 (Mapk9)   09143 Cell growth and death    04210 Apoptosis     101698286 (Mapk9)    04215 Apoptosis - multiple species     101698286 (Mapk9)    04217 Necroptosis     101698286 (Mapk9)   09144 Cellular community - eukaryotes    04510 Focal adhesion     101698286 (Mapk9)    04530 Tight junction     101698286 (Mapk9)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     101698286 (Mapk9)    04621 NOD-like receptor signaling pathway     101698286 (Mapk9)    04622 RIG-I-like receptor signaling pathway     101698286 (Mapk9)    04625 C-type lectin receptor signaling pathway     101698286 (Mapk9)    04660 T cell receptor signaling pathway     101698286 (Mapk9)    04658 Th1 and Th2 cell differentiation     101698286 (Mapk9)    04659 Th17 cell differentiation     101698286 (Mapk9)    04657 IL-17 signaling pathway     101698286 (Mapk9)    04664 Fc epsilon RI signaling pathway     101698286 (Mapk9)   09152 Endocrine system    04910 Insulin signaling pathway     101698286 (Mapk9)    04920 Adipocytokine signaling pathway     101698286 (Mapk9)    04912 GnRH signaling pathway     101698286 (Mapk9)    04914 Progesterone-mediated oocyte maturation     101698286 (Mapk9)    04917 Prolactin signaling pathway     101698286 (Mapk9)    04926 Relaxin signaling pathway     101698286 (Mapk9)    04935 Growth hormone synthesis, secretion and action     101698286 (Mapk9)   09156 Nervous system    04728 Dopaminergic synapse     101698286 (Mapk9)    04723 Retrograde endocannabinoid signaling     101698286 (Mapk9)    04722 Neurotrophin signaling pathway     101698286 (Mapk9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101698286 (Mapk9)   09158 Development and regeneration    04380 Osteoclast differentiation     101698286 (Mapk9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101698286 (Mapk9)    05231 Choline metabolism in cancer     101698286 (Mapk9)   09162 Cancer: specific types    05210 Colorectal cancer     101698286 (Mapk9)    05212 Pancreatic cancer     101698286 (Mapk9)   09164 Neurodegenerative disease    05010 Alzheimer disease     101698286 (Mapk9)    05012 Parkinson disease     101698286 (Mapk9)    05016 Huntington disease     101698286 (Mapk9)    05017 Spinocerebellar ataxia     101698286 (Mapk9)    05020 Prion disease     101698286 (Mapk9)    05022 Pathways of neurodegeneration - multiple diseases     101698286 (Mapk9)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     101698286 (Mapk9)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101698286 (Mapk9)    04932 Non-alcoholic fatty liver disease     101698286 (Mapk9)    04931 Insulin resistance     101698286 (Mapk9)    04933 AGE-RAGE signaling pathway in diabetic complications     101698286 (Mapk9)   09171 Infectious disease: bacterial    05132 Salmonella infection     101698286 (Mapk9)    05135 Yersinia infection     101698286 (Mapk9)    05133 Pertussis     101698286 (Mapk9)    05152 Tuberculosis     101698286 (Mapk9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101698286 (Mapk9)    05170 Human immunodeficiency virus 1 infection     101698286 (Mapk9)    05161 Hepatitis B     101698286 (Mapk9)    05171 Coronavirus disease - COVID-19     101698286 (Mapk9)    05162 Measles     101698286 (Mapk9)    05167 Kaposi sarcoma-associated herpesvirus infection     101698286 (Mapk9)    05169 Epstein-Barr virus infection     101698286 (Mapk9)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     101698286 (Mapk9)    05142 Chagas disease     101698286 (Mapk9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     101698286 (Mapk9)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hgl01001]     101698286 (Mapk9) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.24  mitogen-activated protein kinase      101698286 (Mapk9) Protein kinases [BR:hgl01001]  Serine/threonine kinases: CMGC group   MAPK family [OT]    101698286 (Mapk9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Kdo Kinase-like RIO1 APH FTA2 Motif Other DBs NCBI-GeneID:  101698286 NCBI-ProteinID:  XP_004836798 UniProt:  G5C7A6 LinkDB All DBs Position Un AA seq 424 aa AA seqDB search MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESDRDKIKTSQARDLLSK MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL EGCR NT seq 1275 nt NT seq  +upstreamnt  +downstreamnt atgagtgacagcaaatgtgatagtcagttttacagtgtgcaagtggcagactcaactttc actgtcctgaaacggtaccagcagttgaaaccaattggctctggagcccaagggattgtt tgtgctgcttttgatacagttcttgggattaatgttgcagtcaagaaactaagccgtcct tttcaaaatcaaactcacgcaaagagagcttatcgtgaacttgtcctcttaaaatgtgtc aatcataaaaatatcattagtttgttaaatgtgttcacaccacaaaaaactctagaagaa tttcaagatgtgtatttggttatggaattaatggatgctaacttatgtcaggttattcat atggaattggaccatgaaagaatgtcctaccttctttaccagatgctttgtggtattaaa catctgcattcagctggtataattcatagagatttgaagcctagcaacattgtagtaaaa tcagattgtacccttaagatccttgactttggtctggcccggacggcatgtaccaacttt atgatgaccccctatgtggtaactcggtattaccgggcgcccgaagtcatcctgggcatg ggctacaaagagaacgttgatatctggtcagtgggttgcatcatgggcgagctggtgaaa ggttgtgtgatattccaaggcactgaccatattgatcagtggaataaagttattgagcaa ctgggaacaccatcagcagagttcatgaagaaacttcagccaactgtgagaaattatgta gaaaatcgaccaaagtatcctggaatcaaatttgaagaactctttccagattggatattc ccatcagaatccgatcgagacaaaataaaaacgagtcaagccagagatctgttatcaaaa atgttagtgatcgatcccgacaagcggatctctgtggacgaagccttgcgtcacccctac attactgtgtggtatgaccctgctgaagcagaagcgccaccacctcagatttacgatgcc cagttggaagaaagagaacatgcaattgaagagtggaaagaactaatttacaaagaagta atggactgggaagaaagaagcaagaatggcgttgtaaaagatcaaccttcagatgcagca gtaagtagcaacgccactccttctcagtcgtcctctatcaatgacatttcatccatgtcc actgagcagacactggcctcagacacagacagcagtcttgatgcctccacaggacccctc gaaggttgtcgatga

Heterocephalus glaber (naked mole rat): 101712980 Help Entry 101712980         CDS       T02812                                  Gene name Mapk10 Definition (RefSeq) mitogen-activated protein kinase 10   KO K04440   mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl01522   Endocrine resistance hgl04010   MAPK signaling pathway hgl04012   ErbB signaling pathway hgl04014   Ras signaling pathway hgl04024   cAMP signaling pathway hgl04068   FoxO signaling pathway hgl04071   Sphingolipid signaling pathway hgl04137   Mitophagy - animal hgl04140   Autophagy - animal hgl04141   Protein processing in endoplasmic reticulum hgl04210   Apoptosis hgl04215   Apoptosis - multiple species hgl04217   Necroptosis hgl04310   Wnt signaling pathway hgl04380   Osteoclast differentiation hgl04510   Focal adhesion hgl04530   Tight junction hgl04620   Toll-like receptor signaling pathway hgl04621   NOD-like receptor signaling pathway hgl04622   RIG-I-like receptor signaling pathway hgl04625   C-type lectin receptor signaling pathway hgl04657   IL-17 signaling pathway hgl04658   Th1 and Th2 cell differentiation hgl04659   Th17 cell differentiation hgl04660   T cell receptor signaling pathway hgl04664   Fc epsilon RI signaling pathway hgl04668   TNF signaling pathway hgl04722   Neurotrophin signaling pathway hgl04723   Retrograde endocannabinoid signaling hgl04728   Dopaminergic synapse hgl04750   Inflammatory mediator regulation of TRP channels hgl04910   Insulin signaling pathway hgl04912   GnRH signaling pathway hgl04914   Progesterone-mediated oocyte maturation hgl04917   Prolactin signaling pathway hgl04920   Adipocytokine signaling pathway hgl04926   Relaxin signaling pathway hgl04930   Type II diabetes mellitus hgl04931   Insulin resistance hgl04932   Non-alcoholic fatty liver disease hgl04933   AGE-RAGE signaling pathway in diabetic complications hgl04935   Growth hormone synthesis, secretion and action hgl05010   Alzheimer disease hgl05012   Parkinson disease hgl05016   Huntington disease hgl05017   Spinocerebellar ataxia hgl05020   Prion disease hgl05022   Pathways of neurodegeneration - multiple diseases hgl05132   Salmonella infection hgl05133   Pertussis hgl05135   Yersinia infection hgl05142   Chagas disease hgl05145   Toxoplasmosis hgl05152   Tuberculosis hgl05161   Hepatitis B hgl05162   Measles hgl05166   Human T-cell leukemia virus 1 infection hgl05167   Kaposi sarcoma-associated herpesvirus infection hgl05169   Epstein-Barr virus infection hgl05170   Human immunodeficiency virus 1 infection hgl05171   Coronavirus disease - COVID-19 hgl05200   Pathways in cancer hgl05210   Colorectal cancer hgl05212   Pancreatic cancer hgl05231   Choline metabolism in cancer hgl05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:hgl00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     101712980 (Mapk10)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101712980 (Mapk10)    04012 ErbB signaling pathway     101712980 (Mapk10)    04014 Ras signaling pathway     101712980 (Mapk10)    04310 Wnt signaling pathway     101712980 (Mapk10)    04668 TNF signaling pathway     101712980 (Mapk10)    04068 FoxO signaling pathway     101712980 (Mapk10)    04071 Sphingolipid signaling pathway     101712980 (Mapk10)    04024 cAMP signaling pathway     101712980 (Mapk10)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101712980 (Mapk10)    04137 Mitophagy - animal     101712980 (Mapk10)   09143 Cell growth and death    04210 Apoptosis     101712980 (Mapk10)    04215 Apoptosis - multiple species     101712980 (Mapk10)    04217 Necroptosis     101712980 (Mapk10)   09144 Cellular community - eukaryotes    04510 Focal adhesion     101712980 (Mapk10)    04530 Tight junction     101712980 (Mapk10)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     101712980 (Mapk10)    04621 NOD-like receptor signaling pathway     101712980 (Mapk10)    04622 RIG-I-like receptor signaling pathway     101712980 (Mapk10)    04625 C-type lectin receptor signaling pathway     101712980 (Mapk10)    04660 T cell receptor signaling pathway     101712980 (Mapk10)    04658 Th1 and Th2 cell differentiation     101712980 (Mapk10)    04659 Th17 cell differentiation     101712980 (Mapk10)    04657 IL-17 signaling pathway     101712980 (Mapk10)    04664 Fc epsilon RI signaling pathway     101712980 (Mapk10)   09152 Endocrine system    04910 Insulin signaling pathway     101712980 (Mapk10)    04920 Adipocytokine signaling pathway     101712980 (Mapk10)    04912 GnRH signaling pathway     101712980 (Mapk10)    04914 Progesterone-mediated oocyte maturation     101712980 (Mapk10)    04917 Prolactin signaling pathway     101712980 (Mapk10)    04926 Relaxin signaling pathway     101712980 (Mapk10)    04935 Growth hormone synthesis, secretion and action     101712980 (Mapk10)   09156 Nervous system    04728 Dopaminergic synapse     101712980 (Mapk10)    04723 Retrograde endocannabinoid signaling     101712980 (Mapk10)    04722 Neurotrophin signaling pathway     101712980 (Mapk10)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101712980 (Mapk10)   09158 Development and regeneration    04380 Osteoclast differentiation     101712980 (Mapk10)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101712980 (Mapk10)    05231 Choline metabolism in cancer     101712980 (Mapk10)   09162 Cancer: specific types    05210 Colorectal cancer     101712980 (Mapk10)    05212 Pancreatic cancer     101712980 (Mapk10)   09164 Neurodegenerative disease    05010 Alzheimer disease     101712980 (Mapk10)    05012 Parkinson disease     101712980 (Mapk10)    05016 Huntington disease     101712980 (Mapk10)    05017 Spinocerebellar ataxia     101712980 (Mapk10)    05020 Prion disease     101712980 (Mapk10)    05022 Pathways of neurodegeneration - multiple diseases     101712980 (Mapk10)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     101712980 (Mapk10)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101712980 (Mapk10)    04932 Non-alcoholic fatty liver disease     101712980 (Mapk10)    04931 Insulin resistance     101712980 (Mapk10)    04933 AGE-RAGE signaling pathway in diabetic complications     101712980 (Mapk10)   09171 Infectious disease: bacterial    05132 Salmonella infection     101712980 (Mapk10)    05135 Yersinia infection     101712980 (Mapk10)    05133 Pertussis     101712980 (Mapk10)    05152 Tuberculosis     101712980 (Mapk10)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101712980 (Mapk10)    05170 Human immunodeficiency virus 1 infection     101712980 (Mapk10)    05161 Hepatitis B     101712980 (Mapk10)    05171 Coronavirus disease - COVID-19     101712980 (Mapk10)    05162 Measles     101712980 (Mapk10)    05167 Kaposi sarcoma-associated herpesvirus infection     101712980 (Mapk10)    05169 Epstein-Barr virus infection     101712980 (Mapk10)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     101712980 (Mapk10)    05142 Chagas disease     101712980 (Mapk10)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     101712980 (Mapk10)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hgl01001]     101712980 (Mapk10) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.24  mitogen-activated protein kinase      101712980 (Mapk10) Protein kinases [BR:hgl01001]  Serine/threonine kinases: CMGC group   MAPK family [OT]    101712980 (Mapk10) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Kdo Kinase-like RIO1 APH FTA2 Motif Other DBs NCBI-GeneID:  101712980 NCBI-ProteinID:  XP_004870572 UniProt:  G5C950 LinkDB All DBs Position Un AA seq 464 aa AA seqDB search MSLHFLYYCSEPTLDVKVAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR NT seq 1395 nt NT seq  +upstreamnt  +downstreamnt atgagcctccatttcttatactactgcagtgaaccaaccttggatgtgaaagttgccttt tgtcagggattcgataaacaagtggatgtgtcatatatagccaaacattacaacatgagc aaaagcaaagtggacaaccagttctacagtgtggaagtgggagactcgaccttcacagtt ctcaagcgctaccagaatctaaagcctattggctctggggctcaggggatagtgtgtgct gcatatgatgctgtcctggacagaaatgtggccattaagaagctcagcagaccctttcag aaccaaacgcatgccaagagagcctaccgggagctggtcctcatgaagtgtgtgaaccat aaaaatattattagcttattaaatgtcttcacacctcagaaaacgctggaggagttccag gatgtttacttagtaatggaattgatggacgccaacctgtgtcaggtgattcagatggaa ttagaccatgagcggatgtcgtacctgctataccagatgttgtgtggcatcaaacatctg cactctgctggaattattcacagggatttaaaaccaagtaacattgtagtcaagtccgat tgcacgttgaaaatcctggactttggactggccaggacagcaggcacaagcttcatgatg acgccgtacgtggtgacacgttattacagagccccggaggtcatcctgggaatgggctac aaggagaacgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa atcctctttccaggaagggactatattgaccagtggaataaagtcattgagcaactagga acaccatgtccagaattcatgaagaaattgcagcccacagtaagaaactatgtggagaat cggccaaagtatgctggactcacctttcccaagctctttccagactccctcttcccagcg gactctgagcacaataaacttaaagccagccaagcccgggatttgttgtcaaagatgcta gtgattgacccagccaaaaggatatctgtggacgacgccttacagcacccctacatcaac gtttggtacgaccctgcagaggtggaggcgcctccacctcagatttatgacaaacagctg gatgaaagagaacacaccattgaagaatggaaagaacttatttacaaggaagtaatgaat tcagaagaaaagactaaaaatggtgtagtaaaaggacagccttctccttcaggtgcagca gtgaacagcagtgagagtctccctccatcttcgtccgtcaatgacatctcctccatgtcc accgaccagaccctggcatctgacactgacagcagcttggaagcctcagcgggacccctg ggttgttgcaggtga

Heterocephalus glaber (naked mole rat): 101715259 Help Entry 101715259         CDS       T02812                                  Gene name Mapk8 Definition (RefSeq) mitogen-activated protein kinase 8   KO K04440   mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl01522   Endocrine resistance hgl04010   MAPK signaling pathway hgl04012   ErbB signaling pathway hgl04014   Ras signaling pathway hgl04024   cAMP signaling pathway hgl04068   FoxO signaling pathway hgl04071   Sphingolipid signaling pathway hgl04137   Mitophagy - animal hgl04140   Autophagy - animal hgl04141   Protein processing in endoplasmic reticulum hgl04210   Apoptosis hgl04215   Apoptosis - multiple species hgl04217   Necroptosis hgl04310   Wnt signaling pathway hgl04380   Osteoclast differentiation hgl04510   Focal adhesion hgl04530   Tight junction hgl04620   Toll-like receptor signaling pathway hgl04621   NOD-like receptor signaling pathway hgl04622   RIG-I-like receptor signaling pathway hgl04625   C-type lectin receptor signaling pathway hgl04657   IL-17 signaling pathway hgl04658   Th1 and Th2 cell differentiation hgl04659   Th17 cell differentiation hgl04660   T cell receptor signaling pathway hgl04664   Fc epsilon RI signaling pathway hgl04668   TNF signaling pathway hgl04722   Neurotrophin signaling pathway hgl04723   Retrograde endocannabinoid signaling hgl04728   Dopaminergic synapse hgl04750   Inflammatory mediator regulation of TRP channels hgl04910   Insulin signaling pathway hgl04912   GnRH signaling pathway hgl04914   Progesterone-mediated oocyte maturation hgl04917   Prolactin signaling pathway hgl04920   Adipocytokine signaling pathway hgl04926   Relaxin signaling pathway hgl04930   Type II diabetes mellitus hgl04931   Insulin resistance hgl04932   Non-alcoholic fatty liver disease hgl04933   AGE-RAGE signaling pathway in diabetic complications hgl04935   Growth hormone synthesis, secretion and action hgl05010   Alzheimer disease hgl05012   Parkinson disease hgl05016   Huntington disease hgl05017   Spinocerebellar ataxia hgl05020   Prion disease hgl05022   Pathways of neurodegeneration - multiple diseases hgl05132   Salmonella infection hgl05133   Pertussis hgl05135   Yersinia infection hgl05142   Chagas disease hgl05145   Toxoplasmosis hgl05152   Tuberculosis hgl05161   Hepatitis B hgl05162   Measles hgl05166   Human T-cell leukemia virus 1 infection hgl05167   Kaposi sarcoma-associated herpesvirus infection hgl05169   Epstein-Barr virus infection hgl05170   Human immunodeficiency virus 1 infection hgl05171   Coronavirus disease - COVID-19 hgl05200   Pathways in cancer hgl05210   Colorectal cancer hgl05212   Pancreatic cancer hgl05231   Choline metabolism in cancer hgl05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:hgl00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     101715259 (Mapk8)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101715259 (Mapk8)    04012 ErbB signaling pathway     101715259 (Mapk8)    04014 Ras signaling pathway     101715259 (Mapk8)    04310 Wnt signaling pathway     101715259 (Mapk8)    04668 TNF signaling pathway     101715259 (Mapk8)    04068 FoxO signaling pathway     101715259 (Mapk8)    04071 Sphingolipid signaling pathway     101715259 (Mapk8)    04024 cAMP signaling pathway     101715259 (Mapk8)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101715259 (Mapk8)    04137 Mitophagy - animal     101715259 (Mapk8)   09143 Cell growth and death    04210 Apoptosis     101715259 (Mapk8)    04215 Apoptosis - multiple species     101715259 (Mapk8)    04217 Necroptosis     101715259 (Mapk8)   09144 Cellular community - eukaryotes    04510 Focal adhesion     101715259 (Mapk8)    04530 Tight junction     101715259 (Mapk8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     101715259 (Mapk8)    04621 NOD-like receptor signaling pathway     101715259 (Mapk8)    04622 RIG-I-like receptor signaling pathway     101715259 (Mapk8)    04625 C-type lectin receptor signaling pathway     101715259 (Mapk8)    04660 T cell receptor signaling pathway     101715259 (Mapk8)    04658 Th1 and Th2 cell differentiation     101715259 (Mapk8)    04659 Th17 cell differentiation     101715259 (Mapk8)    04657 IL-17 signaling pathway     101715259 (Mapk8)    04664 Fc epsilon RI signaling pathway     101715259 (Mapk8)   09152 Endocrine system    04910 Insulin signaling pathway     101715259 (Mapk8)    04920 Adipocytokine signaling pathway     101715259 (Mapk8)    04912 GnRH signaling pathway     101715259 (Mapk8)    04914 Progesterone-mediated oocyte maturation     101715259 (Mapk8)    04917 Prolactin signaling pathway     101715259 (Mapk8)    04926 Relaxin signaling pathway     101715259 (Mapk8)    04935 Growth hormone synthesis, secretion and action     101715259 (Mapk8)   09156 Nervous system    04728 Dopaminergic synapse     101715259 (Mapk8)    04723 Retrograde endocannabinoid signaling     101715259 (Mapk8)    04722 Neurotrophin signaling pathway     101715259 (Mapk8)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101715259 (Mapk8)   09158 Development and regeneration    04380 Osteoclast differentiation     101715259 (Mapk8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101715259 (Mapk8)    05231 Choline metabolism in cancer     101715259 (Mapk8)   09162 Cancer: specific types    05210 Colorectal cancer     101715259 (Mapk8)    05212 Pancreatic cancer     101715259 (Mapk8)   09164 Neurodegenerative disease    05010 Alzheimer disease     101715259 (Mapk8)    05012 Parkinson disease     101715259 (Mapk8)    05016 Huntington disease     101715259 (Mapk8)    05017 Spinocerebellar ataxia     101715259 (Mapk8)    05020 Prion disease     101715259 (Mapk8)    05022 Pathways of neurodegeneration - multiple diseases     101715259 (Mapk8)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     101715259 (Mapk8)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101715259 (Mapk8)    04932 Non-alcoholic fatty liver disease     101715259 (Mapk8)    04931 Insulin resistance     101715259 (Mapk8)    04933 AGE-RAGE signaling pathway in diabetic complications     101715259 (Mapk8)   09171 Infectious disease: bacterial    05132 Salmonella infection     101715259 (Mapk8)    05135 Yersinia infection     101715259 (Mapk8)    05133 Pertussis     101715259 (Mapk8)    05152 Tuberculosis     101715259 (Mapk8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101715259 (Mapk8)    05170 Human immunodeficiency virus 1 infection     101715259 (Mapk8)    05161 Hepatitis B     101715259 (Mapk8)    05171 Coronavirus disease - COVID-19     101715259 (Mapk8)    05162 Measles     101715259 (Mapk8)    05167 Kaposi sarcoma-associated herpesvirus infection     101715259 (Mapk8)    05169 Epstein-Barr virus infection     101715259 (Mapk8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     101715259 (Mapk8)    05142 Chagas disease     101715259 (Mapk8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     101715259 (Mapk8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hgl01001]     101715259 (Mapk8) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.24  mitogen-activated protein kinase      101715259 (Mapk8) Protein kinases [BR:hgl01001]  Serine/threonine kinases: CMGC group   MAPK family [OT]    101715259 (Mapk8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Kdo Kinase-like RIO1 APH FTA2 DUF530 Motif Other DBs NCBI-GeneID:  101715259 NCBI-ProteinID:  XP_004874593 UniProt:  G5B0W2 LinkDB All DBs Position Un AA seq 427 aa AA seqDB search MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQ LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA GPLGCCR NT seq 1284 nt NT seq  +upstreamnt  +downstreamnt atgagcagaagcaagcgtgacaacaatttttatagcgtagagattggagattctacattc acagtcctgaaacgataccagaatttaaaacctataggttcaggagctcaaggaatagta tgtgcagcttatgatgctattctggaaagaaatgttgcaatcaagaagctaagccggcca tttcagaatcaaactcatgccaagcgggcctacagagagctagttcttatgaaatgtgtt aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa tttcaagatgtttacatagtcatggagcttatggatgccaatctctgccaagtgattcag atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag caccttcactctgctggaattattcatcgggacttaaaacccagtaacatagtagtaaaa tcagactgcactttgaagattcttgactttggactggctaggactgcaggaacaagtttc atgatgacaccttacgtagtgactcgctactaccgagcacctgaggtcatcttaggcatg ggatacaaggaaaacgtggatttatggtctgtggggtgcattatgggcgaaatggtttgc cacaaaatcctctttccaggaagggactatattgatcagtggaataaagttattgaacag cttggaacaccatgtcctgaattcatgaagaaactacaaccaacagtaaggacttatgtt gaaaacagacctaaatatgctggatatagctttgagaaactcttccctgatgtacttttc ccagctgactcagaacacaacaaacttaaagccagtcaggcacgggatttgttatccaaa atgctggtaatagatgcatctaaaaggatctccgtggatgaagcactccagcacccatac atcaatgtctggtatgatccctccgaagcggaagctccaccaccaaagatccccgacaaa cagttagatgaaagggaacacacaatagaagagtggaaagaattgatatacaaggaagtg atggacttagaggagagaaccaagaatggagttatccgggggcagccttctcctttaggt gcagcagtgatcaatggctctcagcatccatcgtcatcatcatctgtcaatgatgtgtct tcaatgtccacagatccgactttggcctcggataccgacagcagtctagaagcatcagct ggacctctgggctgctgtagatga

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