Heterocephalus glaber (naked mole rat): 101701336
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Entry
101701336 CDS
T02812
Gene name
Ptpn11
Definition
(RefSeq) protein tyrosine phosphatase, non-receptor type 11
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
hgl
Heterocephalus glaber (naked mole rat)
Pathway
hgl04014
Ras signaling pathway
hgl04072
Phospholipase D signaling pathway
hgl04360
Axon guidance
hgl04625
C-type lectin receptor signaling pathway
hgl04630
JAK-STAT signaling pathway
hgl04650
Natural killer cell mediated cytotoxicity
hgl04670
Leukocyte transendothelial migration
hgl04722
Neurotrophin signaling pathway
hgl04920
Adipocytokine signaling pathway
hgl04931
Insulin resistance
hgl05168
Herpes simplex virus 1 infection
hgl05205
Proteoglycans in cancer
hgl05211
Renal cell carcinoma
hgl05220
Chronic myeloid leukemia
hgl05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
101701336 (Ptpn11)
04630 JAK-STAT signaling pathway
101701336 (Ptpn11)
04072 Phospholipase D signaling pathway
101701336 (Ptpn11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
101701336 (Ptpn11)
04650 Natural killer cell mediated cytotoxicity
101701336 (Ptpn11)
04670 Leukocyte transendothelial migration
101701336 (Ptpn11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
101701336 (Ptpn11)
09156 Nervous system
04722 Neurotrophin signaling pathway
101701336 (Ptpn11)
09158 Development and regeneration
04360 Axon guidance
101701336 (Ptpn11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
101701336 (Ptpn11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101701336 (Ptpn11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
101701336 (Ptpn11)
05211 Renal cell carcinoma
101701336 (Ptpn11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
101701336 (Ptpn11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
101701336 (Ptpn11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hgl01009
]
101701336 (Ptpn11)
Enzymes [BR:
hgl01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
101701336 (Ptpn11)
Protein phosphatases and associated proteins [BR:
hgl01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
101701336 (Ptpn11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
DSPc
Y_phosphatase3
PTPlike_phytase
Motif
Other DBs
NCBI-GeneID:
101701336
NCBI-ProteinID:
XP_004843821
UniProt:
A0A0P6JGT2
LinkDB
All DBs
Position
Un
AA seq
593 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF
RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR
EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH
EYTNIKYSLADQASGDQSPLPPCTPTPPCAEMREDNARVYENVGLMQQQKSFR
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaacatcactggagtggaggcagaaaatctactg
ttgaccagaggagttgatggcagttttttggcgaggcccagtaaaagtaaccccggagac
ttcacactttcagttagaagaaatggagctgtcacccacatcaagattcagaacacgggt
gactactatgatctgtacggaggggagaagtttgccactttggctgagctggtccagtat
tacatggaacatcatgggcagctgaaagagaagaatggagatgttatcgagctcaaatat
ccactgaactgtgcagatcctacctctgaaaggtggtttcatggtcacctctctgggaaa
gaagcagagaaattactaaccgagaagggaaaacatggtagctttcttgtccgagagagc
cagagccaccctggagattttgttctctctgtccgcacgggtgatgacaaaggggagagc
aatgatggcaaatctaaagtgacccacgtcatgatccgctgccaggaactgaaatatgat
gttggtggaggagaacggtttgattccttgacagatctggtggagcattacaagaagaat
ccgatggtagaaacattgggcacagtactccaactcaagcagcccctcaacacaactcgt
atcaatgctgctgaaattgaaagtcgggttcgagaattgagcaaattagccgagaccaca
gataaagtcaaacaaggcttctgggaagaatttgagacactacaacaacaggagtgcaaa
cttctctacagccgaaaagagggccagaggcaagaaaataaaaacaaaaatagatacaaa
aatatcctgccctttgatcacaccagggtggtcctccacgacggtgaccccaacgagccc
gtgtctgactacatcaacgcaaacatcatcatgcctgaattcgaaaccaagtgcaacaat
tcaaagcccaaaaagagctacattgccacacaaggctgcctgcaaaacacggtgaacgac
ttttggcgaatggtgttccaggagaattctcgagtgatcgtcatgacgacaaaagaagtg
gagcgaggaaagagcaaatgtgtcaagtactggccggatgagtacgctctcaaagagtat
ggggtcatgcgcgtcaggaatgtcaaagagagtgccgcacatgactacacgctaagagaa
ctgaaactctcgaaggttggacaagggaatacggagagaacggtctggcaataccacttt
cggacctggccggaccacggcgtgcccagtgaccccgggggcgtgttagacttcctggag
gaggtccaccacaagcaggagagcatcatggacgcgggccctgtcgtggtgcactgcagt
gctggaattggccggacaggaacattcattgtgattgatatccttattgacatcatcaga
gagaaaggtgtcgactgcgacatcgatgttcccaaaaccattcaaatggtacggtctcag
aggtcagggatggtccagacagaagcacagtaccggtttatctacatggctgtccagcat
tatattgaaacactacagcgaaggattgaagaagagcagaaaagcaagaggaaagggcac
gaatataccaatattaagtattccctagcggaccaggcaagtggcgatcagagtcccctc
ccaccgtgtacgccaacaccaccctgtgcagaaatgagagaagacaatgccagagtctat
gagaacgtgggcttgatgcagcagcagaagagcttcagatga
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