Heterocephalus glaber (naked mole rat): 101702687 Help Entry 101702687         CDS       T02812                                  Gene name Mapk3 Definition (RefSeq) mitogen-activated protein kinase 3   KO K04371   mitogen-activated protein kinase 1/3 [EC:2.7.11.24] Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl01521   EGFR tyrosine kinase inhibitor resistance hgl01522   Endocrine resistance hgl01524   Platinum drug resistance hgl04010   MAPK signaling pathway hgl04012   ErbB signaling pathway hgl04014   Ras signaling pathway hgl04015   Rap1 signaling pathway hgl04022   cGMP-PKG signaling pathway hgl04024   cAMP signaling pathway hgl04062   Chemokine signaling pathway hgl04066   HIF-1 signaling pathway hgl04068   FoxO signaling pathway hgl04071   Sphingolipid signaling pathway hgl04072   Phospholipase D signaling pathway hgl04114   Oocyte meiosis hgl04140   Autophagy - animal hgl04150   mTOR signaling pathway hgl04151   PI3K-Akt signaling pathway hgl04210   Apoptosis hgl04218   Cellular senescence hgl04261   Adrenergic signaling in cardiomyocytes hgl04270   Vascular smooth muscle contraction hgl04350   TGF-beta signaling pathway hgl04360   Axon guidance hgl04370   VEGF signaling pathway hgl04371   Apelin signaling pathway hgl04380   Osteoclast differentiation hgl04510   Focal adhesion hgl04520   Adherens junction hgl04540   Gap junction hgl04550   Signaling pathways regulating pluripotency of stem cells hgl04611   Platelet activation hgl04613   Neutrophil extracellular trap formation hgl04620   Toll-like receptor signaling pathway hgl04621   NOD-like receptor signaling pathway hgl04625   C-type lectin receptor signaling pathway hgl04650   Natural killer cell mediated cytotoxicity hgl04657   IL-17 signaling pathway hgl04658   Th1 and Th2 cell differentiation hgl04659   Th17 cell differentiation hgl04660   T cell receptor signaling pathway hgl04662   B cell receptor signaling pathway hgl04664   Fc epsilon RI signaling pathway hgl04666   Fc gamma R-mediated phagocytosis hgl04668   TNF signaling pathway hgl04713   Circadian entrainment hgl04720   Long-term potentiation hgl04722   Neurotrophin signaling pathway hgl04723   Retrograde endocannabinoid signaling hgl04724   Glutamatergic synapse hgl04725   Cholinergic synapse hgl04726   Serotonergic synapse hgl04730   Long-term depression hgl04810   Regulation of actin cytoskeleton hgl04910   Insulin signaling pathway hgl04912   GnRH signaling pathway hgl04914   Progesterone-mediated oocyte maturation hgl04915   Estrogen signaling pathway hgl04916   Melanogenesis hgl04917   Prolactin signaling pathway hgl04919   Thyroid hormone signaling pathway hgl04921   Oxytocin signaling pathway hgl04926   Relaxin signaling pathway hgl04928   Parathyroid hormone synthesis, secretion and action hgl04929   GnRH secretion hgl04930   Type II diabetes mellitus hgl04933   AGE-RAGE signaling pathway in diabetic complications hgl04934   Cushing syndrome hgl04935   Growth hormone synthesis, secretion and action hgl04960   Aldosterone-regulated sodium reabsorption hgl05010   Alzheimer disease hgl05020   Prion disease hgl05022   Pathways of neurodegeneration - multiple diseases hgl05034   Alcoholism hgl05132   Salmonella infection hgl05133   Pertussis hgl05135   Yersinia infection hgl05140   Leishmaniasis hgl05142   Chagas disease hgl05145   Toxoplasmosis hgl05152   Tuberculosis hgl05160   Hepatitis C hgl05161   Hepatitis B hgl05163   Human cytomegalovirus infection hgl05164   Influenza A hgl05165   Human papillomavirus infection hgl05166   Human T-cell leukemia virus 1 infection hgl05167   Kaposi sarcoma-associated herpesvirus infection hgl05170   Human immunodeficiency virus 1 infection hgl05171   Coronavirus disease - COVID-19 hgl05200   Pathways in cancer hgl05203   Viral carcinogenesis hgl05205   Proteoglycans in cancer hgl05206   MicroRNAs in cancer hgl05210   Colorectal cancer hgl05211   Renal cell carcinoma hgl05212   Pancreatic cancer hgl05213   Endometrial cancer hgl05214   Glioma hgl05215   Prostate cancer hgl05216   Thyroid cancer hgl05218   Melanoma hgl05219   Bladder cancer hgl05220   Chronic myeloid leukemia hgl05221   Acute myeloid leukemia hgl05223   Non-small cell lung cancer hgl05224   Breast cancer hgl05225   Hepatocellular carcinoma hgl05226   Gastric cancer hgl05230   Central carbon metabolism in cancer hgl05231   Choline metabolism in cancer hgl05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101702687 (Mapk3)    04012 ErbB signaling pathway     101702687 (Mapk3)    04014 Ras signaling pathway     101702687 (Mapk3)    04015 Rap1 signaling pathway     101702687 (Mapk3)    04350 TGF-beta signaling pathway     101702687 (Mapk3)    04370 VEGF signaling pathway     101702687 (Mapk3)    04371 Apelin signaling pathway     101702687 (Mapk3)    04668 TNF signaling pathway     101702687 (Mapk3)    04066 HIF-1 signaling pathway     101702687 (Mapk3)    04068 FoxO signaling pathway     101702687 (Mapk3)    04072 Phospholipase D signaling pathway     101702687 (Mapk3)    04071 Sphingolipid signaling pathway     101702687 (Mapk3)    04024 cAMP signaling pathway     101702687 (Mapk3)    04022 cGMP-PKG signaling pathway     101702687 (Mapk3)    04151 PI3K-Akt signaling pathway     101702687 (Mapk3)    04150 mTOR signaling pathway     101702687 (Mapk3)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101702687 (Mapk3)   09143 Cell growth and death    04114 Oocyte meiosis     101702687 (Mapk3)    04210 Apoptosis     101702687 (Mapk3)    04218 Cellular senescence     101702687 (Mapk3)   09144 Cellular community - eukaryotes    04510 Focal adhesion     101702687 (Mapk3)    04520 Adherens junction     101702687 (Mapk3)    04540 Gap junction     101702687 (Mapk3)    04550 Signaling pathways regulating pluripotency of stem cells     101702687 (Mapk3)   09142 Cell motility    04810 Regulation of actin cytoskeleton     101702687 (Mapk3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101702687 (Mapk3)    04613 Neutrophil extracellular trap formation     101702687 (Mapk3)    04620 Toll-like receptor signaling pathway     101702687 (Mapk3)    04621 NOD-like receptor signaling pathway     101702687 (Mapk3)    04625 C-type lectin receptor signaling pathway     101702687 (Mapk3)    04650 Natural killer cell mediated cytotoxicity     101702687 (Mapk3)    04660 T cell receptor signaling pathway     101702687 (Mapk3)    04658 Th1 and Th2 cell differentiation     101702687 (Mapk3)    04659 Th17 cell differentiation     101702687 (Mapk3)    04657 IL-17 signaling pathway     101702687 (Mapk3)    04662 B cell receptor signaling pathway     101702687 (Mapk3)    04664 Fc epsilon RI signaling pathway     101702687 (Mapk3)    04666 Fc gamma R-mediated phagocytosis     101702687 (Mapk3)    04062 Chemokine signaling pathway     101702687 (Mapk3)   09152 Endocrine system    04910 Insulin signaling pathway     101702687 (Mapk3)    04929 GnRH secretion     101702687 (Mapk3)    04912 GnRH signaling pathway     101702687 (Mapk3)    04915 Estrogen signaling pathway     101702687 (Mapk3)    04914 Progesterone-mediated oocyte maturation     101702687 (Mapk3)    04917 Prolactin signaling pathway     101702687 (Mapk3)    04921 Oxytocin signaling pathway     101702687 (Mapk3)    04926 Relaxin signaling pathway     101702687 (Mapk3)    04935 Growth hormone synthesis, secretion and action     101702687 (Mapk3)    04919 Thyroid hormone signaling pathway     101702687 (Mapk3)    04928 Parathyroid hormone synthesis, secretion and action     101702687 (Mapk3)    04916 Melanogenesis     101702687 (Mapk3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     101702687 (Mapk3)    04270 Vascular smooth muscle contraction     101702687 (Mapk3)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     101702687 (Mapk3)   09156 Nervous system    04724 Glutamatergic synapse     101702687 (Mapk3)    04725 Cholinergic synapse     101702687 (Mapk3)    04726 Serotonergic synapse     101702687 (Mapk3)    04720 Long-term potentiation     101702687 (Mapk3)    04730 Long-term depression     101702687 (Mapk3)    04723 Retrograde endocannabinoid signaling     101702687 (Mapk3)    04722 Neurotrophin signaling pathway     101702687 (Mapk3)   09158 Development and regeneration    04360 Axon guidance     101702687 (Mapk3)    04380 Osteoclast differentiation     101702687 (Mapk3)   09159 Environmental adaptation    04713 Circadian entrainment     101702687 (Mapk3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101702687 (Mapk3)    05206 MicroRNAs in cancer     101702687 (Mapk3)    05205 Proteoglycans in cancer     101702687 (Mapk3)    05203 Viral carcinogenesis     101702687 (Mapk3)    05230 Central carbon metabolism in cancer     101702687 (Mapk3)    05231 Choline metabolism in cancer     101702687 (Mapk3)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     101702687 (Mapk3)   09162 Cancer: specific types    05210 Colorectal cancer     101702687 (Mapk3)    05212 Pancreatic cancer     101702687 (Mapk3)    05225 Hepatocellular carcinoma     101702687 (Mapk3)    05226 Gastric cancer     101702687 (Mapk3)    05214 Glioma     101702687 (Mapk3)    05216 Thyroid cancer     101702687 (Mapk3)    05221 Acute myeloid leukemia     101702687 (Mapk3)    05220 Chronic myeloid leukemia     101702687 (Mapk3)    05218 Melanoma     101702687 (Mapk3)    05211 Renal cell carcinoma     101702687 (Mapk3)    05219 Bladder cancer     101702687 (Mapk3)    05215 Prostate cancer     101702687 (Mapk3)    05213 Endometrial cancer     101702687 (Mapk3)    05224 Breast cancer     101702687 (Mapk3)    05223 Non-small cell lung cancer     101702687 (Mapk3)   09164 Neurodegenerative disease    05010 Alzheimer disease     101702687 (Mapk3)    05020 Prion disease     101702687 (Mapk3)    05022 Pathways of neurodegeneration - multiple diseases     101702687 (Mapk3)   09165 Substance dependence    05034 Alcoholism     101702687 (Mapk3)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101702687 (Mapk3)    04933 AGE-RAGE signaling pathway in diabetic complications     101702687 (Mapk3)    04934 Cushing syndrome     101702687 (Mapk3)   09171 Infectious disease: bacterial    05132 Salmonella infection     101702687 (Mapk3)    05135 Yersinia infection     101702687 (Mapk3)    05133 Pertussis     101702687 (Mapk3)    05152 Tuberculosis     101702687 (Mapk3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101702687 (Mapk3)    05170 Human immunodeficiency virus 1 infection     101702687 (Mapk3)    05161 Hepatitis B     101702687 (Mapk3)    05160 Hepatitis C     101702687 (Mapk3)    05171 Coronavirus disease - COVID-19     101702687 (Mapk3)    05164 Influenza A     101702687 (Mapk3)    05163 Human cytomegalovirus infection     101702687 (Mapk3)    05167 Kaposi sarcoma-associated herpesvirus infection     101702687 (Mapk3)    05165 Human papillomavirus infection     101702687 (Mapk3)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     101702687 (Mapk3)    05140 Leishmaniasis     101702687 (Mapk3)    05142 Chagas disease     101702687 (Mapk3)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101702687 (Mapk3)    01524 Platinum drug resistance     101702687 (Mapk3)    01522 Endocrine resistance     101702687 (Mapk3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hgl01001]     101702687 (Mapk3)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:hgl03036]     101702687 (Mapk3)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hgl04147]     101702687 (Mapk3) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.24  mitogen-activated protein kinase      101702687 (Mapk3) Protein kinases [BR:hgl01001]  Serine/threonine kinases: CMGC group   MAPK family [OT]    101702687 (Mapk3) Chromosome and associated proteins [BR:hgl03036]  Eukaryotic type   Centromeric chromatin formation proteins    SAC (spindle assembly checkpoint) factors     Protein kinases      101702687 (Mapk3) Exosome [BR:hgl04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    101702687 (Mapk3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr APH Choline_kinase FTA2 Kdo Motif Other DBs NCBI-GeneID:  101702687 NCBI-ProteinID:  XP_004856331 LinkDB All DBs Position Un AA seq 378 aa AA seqDB search MAAAAQGGGGGEPRGAGGVGPGVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYD HVLKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIV QDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLK ICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN RPIFPGKHYLDQLNHILGILGSPSQEDLNCIINTKARNYLQSLPSKTKVAWAKLFPKSDS KALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPKERLK ELIFQETARFQPGAQDVP NT seq 1137 nt NT seq  +upstreamnt  +downstreamnt atggcggcggctgctcaggggggcgggggcggggagccccggggagccggcggggtgggc ccgggggtcccgggggaagtggaggtggtgaagggccagccgttcgacgtgggcccgcgc tacacgcagctgcagtacatcggcgagggagcctacggcatggtcagctcagcgtatgac cacgtgctcaagactcgagtggccataaagaaaatcagccccttcgagcatcagacctac tgccagcgaacactacgggagatccagatcttgctgcgcttccgccacgagaatgtcata ggcatccgagatattcttcgggcgcctaccctggaagccatgagagatgtgtacattgtg caggacctgatggagacagacctgtacaagttgctcaaaagccagcagctgagcaatgac catatctgctacttcctctaccagatccttcggggcctcaagtatatccactcagccaat gtactccaccgggatctaaagccctccaacctgctcatcaacaccacctgcgaccttaag atctgtgatttcggcctggcccggattgctgatcctgagcatgaccacactggctttctg accgaatatgtggccacacgctggtaccgggctccggagatcatgcttaactccaagggc tataccaaatccattgacatctggtctgtgggctgcattctggctgagatgctctccaac cgacccatcttccccggcaagcactacctggaccagctcaaccacattctgggtatcctg ggctccccatcccaggaggacctgaattgtatcattaacacgaaggcccggaactaccta cagtctctgccctctaagaccaaggtggcctgggccaagctttttcccaagtcagactcc aaagctcttgacctcctggacaggatgttaaccttcaaccccaataagcggatcacagtg gaggaggccctggctcacccctacctggagcagtactatgaccccacagatgagccagtg gctgaggagcccttcactttcgacatggagctggatgatctgcccaaggagcggctgaag gagcttatcttccaagagacagcccgctttcagccaggggcgcaagacgtcccctaa

Heterocephalus glaber (naked mole rat): 101706099 Help Entry 101706099         CDS       T02812                                  Gene name Mapk1 Definition (RefSeq) mitogen-activated protein kinase 1   KO K04371   mitogen-activated protein kinase 1/3 [EC:2.7.11.24] Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl01521   EGFR tyrosine kinase inhibitor resistance hgl01522   Endocrine resistance hgl01524   Platinum drug resistance hgl04010   MAPK signaling pathway hgl04012   ErbB signaling pathway hgl04014   Ras signaling pathway hgl04015   Rap1 signaling pathway hgl04022   cGMP-PKG signaling pathway hgl04024   cAMP signaling pathway hgl04062   Chemokine signaling pathway hgl04066   HIF-1 signaling pathway hgl04068   FoxO signaling pathway hgl04071   Sphingolipid signaling pathway hgl04072   Phospholipase D signaling pathway hgl04114   Oocyte meiosis hgl04140   Autophagy - animal hgl04150   mTOR signaling pathway hgl04151   PI3K-Akt signaling pathway hgl04210   Apoptosis hgl04218   Cellular senescence hgl04261   Adrenergic signaling in cardiomyocytes hgl04270   Vascular smooth muscle contraction hgl04350   TGF-beta signaling pathway hgl04360   Axon guidance hgl04370   VEGF signaling pathway hgl04371   Apelin signaling pathway hgl04380   Osteoclast differentiation hgl04510   Focal adhesion hgl04520   Adherens junction hgl04540   Gap junction hgl04550   Signaling pathways regulating pluripotency of stem cells hgl04611   Platelet activation hgl04613   Neutrophil extracellular trap formation hgl04620   Toll-like receptor signaling pathway hgl04621   NOD-like receptor signaling pathway hgl04625   C-type lectin receptor signaling pathway hgl04650   Natural killer cell mediated cytotoxicity hgl04657   IL-17 signaling pathway hgl04658   Th1 and Th2 cell differentiation hgl04659   Th17 cell differentiation hgl04660   T cell receptor signaling pathway hgl04662   B cell receptor signaling pathway hgl04664   Fc epsilon RI signaling pathway hgl04666   Fc gamma R-mediated phagocytosis hgl04668   TNF signaling pathway hgl04713   Circadian entrainment hgl04720   Long-term potentiation hgl04722   Neurotrophin signaling pathway hgl04723   Retrograde endocannabinoid signaling hgl04724   Glutamatergic synapse hgl04725   Cholinergic synapse hgl04726   Serotonergic synapse hgl04730   Long-term depression hgl04810   Regulation of actin cytoskeleton hgl04910   Insulin signaling pathway hgl04912   GnRH signaling pathway hgl04914   Progesterone-mediated oocyte maturation hgl04915   Estrogen signaling pathway hgl04916   Melanogenesis hgl04917   Prolactin signaling pathway hgl04919   Thyroid hormone signaling pathway hgl04921   Oxytocin signaling pathway hgl04926   Relaxin signaling pathway hgl04928   Parathyroid hormone synthesis, secretion and action hgl04929   GnRH secretion hgl04930   Type II diabetes mellitus hgl04933   AGE-RAGE signaling pathway in diabetic complications hgl04934   Cushing syndrome hgl04935   Growth hormone synthesis, secretion and action hgl04960   Aldosterone-regulated sodium reabsorption hgl05010   Alzheimer disease hgl05020   Prion disease hgl05022   Pathways of neurodegeneration - multiple diseases hgl05034   Alcoholism hgl05132   Salmonella infection hgl05133   Pertussis hgl05135   Yersinia infection hgl05140   Leishmaniasis hgl05142   Chagas disease hgl05145   Toxoplasmosis hgl05152   Tuberculosis hgl05160   Hepatitis C hgl05161   Hepatitis B hgl05163   Human cytomegalovirus infection hgl05164   Influenza A hgl05165   Human papillomavirus infection hgl05166   Human T-cell leukemia virus 1 infection hgl05167   Kaposi sarcoma-associated herpesvirus infection hgl05170   Human immunodeficiency virus 1 infection hgl05171   Coronavirus disease - COVID-19 hgl05200   Pathways in cancer hgl05203   Viral carcinogenesis hgl05205   Proteoglycans in cancer hgl05206   MicroRNAs in cancer hgl05210   Colorectal cancer hgl05211   Renal cell carcinoma hgl05212   Pancreatic cancer hgl05213   Endometrial cancer hgl05214   Glioma hgl05215   Prostate cancer hgl05216   Thyroid cancer hgl05218   Melanoma hgl05219   Bladder cancer hgl05220   Chronic myeloid leukemia hgl05221   Acute myeloid leukemia hgl05223   Non-small cell lung cancer hgl05224   Breast cancer hgl05225   Hepatocellular carcinoma hgl05226   Gastric cancer hgl05230   Central carbon metabolism in cancer hgl05231   Choline metabolism in cancer hgl05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101706099 (Mapk1)    04012 ErbB signaling pathway     101706099 (Mapk1)    04014 Ras signaling pathway     101706099 (Mapk1)    04015 Rap1 signaling pathway     101706099 (Mapk1)    04350 TGF-beta signaling pathway     101706099 (Mapk1)    04370 VEGF signaling pathway     101706099 (Mapk1)    04371 Apelin signaling pathway     101706099 (Mapk1)    04668 TNF signaling pathway     101706099 (Mapk1)    04066 HIF-1 signaling pathway     101706099 (Mapk1)    04068 FoxO signaling pathway     101706099 (Mapk1)    04072 Phospholipase D signaling pathway     101706099 (Mapk1)    04071 Sphingolipid signaling pathway     101706099 (Mapk1)    04024 cAMP signaling pathway     101706099 (Mapk1)    04022 cGMP-PKG signaling pathway     101706099 (Mapk1)    04151 PI3K-Akt signaling pathway     101706099 (Mapk1)    04150 mTOR signaling pathway     101706099 (Mapk1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101706099 (Mapk1)   09143 Cell growth and death    04114 Oocyte meiosis     101706099 (Mapk1)    04210 Apoptosis     101706099 (Mapk1)    04218 Cellular senescence     101706099 (Mapk1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     101706099 (Mapk1)    04520 Adherens junction     101706099 (Mapk1)    04540 Gap junction     101706099 (Mapk1)    04550 Signaling pathways regulating pluripotency of stem cells     101706099 (Mapk1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     101706099 (Mapk1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101706099 (Mapk1)    04613 Neutrophil extracellular trap formation     101706099 (Mapk1)    04620 Toll-like receptor signaling pathway     101706099 (Mapk1)    04621 NOD-like receptor signaling pathway     101706099 (Mapk1)    04625 C-type lectin receptor signaling pathway     101706099 (Mapk1)    04650 Natural killer cell mediated cytotoxicity     101706099 (Mapk1)    04660 T cell receptor signaling pathway     101706099 (Mapk1)    04658 Th1 and Th2 cell differentiation     101706099 (Mapk1)    04659 Th17 cell differentiation     101706099 (Mapk1)    04657 IL-17 signaling pathway     101706099 (Mapk1)    04662 B cell receptor signaling pathway     101706099 (Mapk1)    04664 Fc epsilon RI signaling pathway     101706099 (Mapk1)    04666 Fc gamma R-mediated phagocytosis     101706099 (Mapk1)    04062 Chemokine signaling pathway     101706099 (Mapk1)   09152 Endocrine system    04910 Insulin signaling pathway     101706099 (Mapk1)    04929 GnRH secretion     101706099 (Mapk1)    04912 GnRH signaling pathway     101706099 (Mapk1)    04915 Estrogen signaling pathway     101706099 (Mapk1)    04914 Progesterone-mediated oocyte maturation     101706099 (Mapk1)    04917 Prolactin signaling pathway     101706099 (Mapk1)    04921 Oxytocin signaling pathway     101706099 (Mapk1)    04926 Relaxin signaling pathway     101706099 (Mapk1)    04935 Growth hormone synthesis, secretion and action     101706099 (Mapk1)    04919 Thyroid hormone signaling pathway     101706099 (Mapk1)    04928 Parathyroid hormone synthesis, secretion and action     101706099 (Mapk1)    04916 Melanogenesis     101706099 (Mapk1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     101706099 (Mapk1)    04270 Vascular smooth muscle contraction     101706099 (Mapk1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     101706099 (Mapk1)   09156 Nervous system    04724 Glutamatergic synapse     101706099 (Mapk1)    04725 Cholinergic synapse     101706099 (Mapk1)    04726 Serotonergic synapse     101706099 (Mapk1)    04720 Long-term potentiation     101706099 (Mapk1)    04730 Long-term depression     101706099 (Mapk1)    04723 Retrograde endocannabinoid signaling     101706099 (Mapk1)    04722 Neurotrophin signaling pathway     101706099 (Mapk1)   09158 Development and regeneration    04360 Axon guidance     101706099 (Mapk1)    04380 Osteoclast differentiation     101706099 (Mapk1)   09159 Environmental adaptation    04713 Circadian entrainment     101706099 (Mapk1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101706099 (Mapk1)    05206 MicroRNAs in cancer     101706099 (Mapk1)    05205 Proteoglycans in cancer     101706099 (Mapk1)    05203 Viral carcinogenesis     101706099 (Mapk1)    05230 Central carbon metabolism in cancer     101706099 (Mapk1)    05231 Choline metabolism in cancer     101706099 (Mapk1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     101706099 (Mapk1)   09162 Cancer: specific types    05210 Colorectal cancer     101706099 (Mapk1)    05212 Pancreatic cancer     101706099 (Mapk1)    05225 Hepatocellular carcinoma     101706099 (Mapk1)    05226 Gastric cancer     101706099 (Mapk1)    05214 Glioma     101706099 (Mapk1)    05216 Thyroid cancer     101706099 (Mapk1)    05221 Acute myeloid leukemia     101706099 (Mapk1)    05220 Chronic myeloid leukemia     101706099 (Mapk1)    05218 Melanoma     101706099 (Mapk1)    05211 Renal cell carcinoma     101706099 (Mapk1)    05219 Bladder cancer     101706099 (Mapk1)    05215 Prostate cancer     101706099 (Mapk1)    05213 Endometrial cancer     101706099 (Mapk1)    05224 Breast cancer     101706099 (Mapk1)    05223 Non-small cell lung cancer     101706099 (Mapk1)   09164 Neurodegenerative disease    05010 Alzheimer disease     101706099 (Mapk1)    05020 Prion disease     101706099 (Mapk1)    05022 Pathways of neurodegeneration - multiple diseases     101706099 (Mapk1)   09165 Substance dependence    05034 Alcoholism     101706099 (Mapk1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101706099 (Mapk1)    04933 AGE-RAGE signaling pathway in diabetic complications     101706099 (Mapk1)    04934 Cushing syndrome     101706099 (Mapk1)   09171 Infectious disease: bacterial    05132 Salmonella infection     101706099 (Mapk1)    05135 Yersinia infection     101706099 (Mapk1)    05133 Pertussis     101706099 (Mapk1)    05152 Tuberculosis     101706099 (Mapk1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101706099 (Mapk1)    05170 Human immunodeficiency virus 1 infection     101706099 (Mapk1)    05161 Hepatitis B     101706099 (Mapk1)    05160 Hepatitis C     101706099 (Mapk1)    05171 Coronavirus disease - COVID-19     101706099 (Mapk1)    05164 Influenza A     101706099 (Mapk1)    05163 Human cytomegalovirus infection     101706099 (Mapk1)    05167 Kaposi sarcoma-associated herpesvirus infection     101706099 (Mapk1)    05165 Human papillomavirus infection     101706099 (Mapk1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     101706099 (Mapk1)    05140 Leishmaniasis     101706099 (Mapk1)    05142 Chagas disease     101706099 (Mapk1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101706099 (Mapk1)    01524 Platinum drug resistance     101706099 (Mapk1)    01522 Endocrine resistance     101706099 (Mapk1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hgl01001]     101706099 (Mapk1)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:hgl03036]     101706099 (Mapk1)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hgl04147]     101706099 (Mapk1) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.24  mitogen-activated protein kinase      101706099 (Mapk1) Protein kinases [BR:hgl01001]  Serine/threonine kinases: CMGC group   MAPK family [OT]    101706099 (Mapk1) Chromosome and associated proteins [BR:hgl03036]  Eukaryotic type   Centromeric chromatin formation proteins    SAC (spindle assembly checkpoint) factors     Protein kinases      101706099 (Mapk1) Exosome [BR:hgl04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    101706099 (Mapk1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr APH FTA2 Choline_kinase Kdo Kinase-like Motif Other DBs NCBI-GeneID:  101706099 NCBI-ProteinID:  XP_004843379 LinkDB All DBs Position Un AA seq 360 aa AA seqDB search MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNINKVRVAIKKISPFE HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS NT seq 1083 nt NT seq  +upstreamnt  +downstreamnt atggcggcggcagcggcggcgggcgcgggcccggagatggtccgcgggcaggtgttcgac gtgggtccgcgctacaccaatctctcgtacattggcgagggcgcctacggcatggtgtgc tcagcatatgataacatcaacaaagttcgagtagctatcaagaaaatcagtcctttcgaa caccagacttactgccagagaaccctgagggagataaaaatcttactgcgcttcagacat gagaacatcattggcatcaatgatattattcgtgcaccaaccatcgagcaaatgaaagat gtatatatagtacaggacctaatggaaacagatctttacaagctcttgaagacacaacac ctcagcaacgaccatatctgctattttctttaccagatcctcagagggttaaaatatatc cactcagctaatgttctgcaccgtgacctcaagccttccaacctgctgcttaacaccacc tgtgatctcaagatctgtgactttggcctggctcgtgttgcagatccagatcatgatcac acagggttcctgacagagtatgtagccacacgttggtacagagctccagaaataatgttg aattccaagggctataccaagtccattgatatttggtcagtgggctgcatcctggcagag atgctgtccaacagacccatctttccagggaagcattatctcgaccagctgaaccacatt ctaggtattcttggatccccatcacaggaagacctgaattgtataataaatttaaaagct agaaactatttgctttctcttccacacaaaaataaggtgccatggaacaggctgttccca aatgctgactccaaagctctggacttactggacaaaatgttgacattcaatcctcacaag aggattgaggttgaacaagctctagcccacccatatctggagcagtattatgacccaagt gatgagcccattgctgaagcaccattcaagtttgacatggaattggatgacttgcctaag gaaaagctcaaagaactcatttttgaagagactgctagattccagccaggatacagatct taa

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