Heterocephalus glaber (naked mole rat): 101703084 Help Entry 101703084         CDS       T02812                                  Gene name Socs5 Definition (RefSeq) suppressor of cytokine signaling 5   KO K04698   suppressor of cytokine signaling 5 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04630   JAK-STAT signaling pathway hgl04917   Prolactin signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101703084 (Socs5)  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     101703084 (Socs5)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:hgl04121]     101703084 (Socs5) Ubiquitin system [BR:hgl04121]  Ubiquitin ligases (E3)   Multi subunit Ring-finger type E3    ECS complex     Target recognizing subunit (SOCS box)      101703084 (Socs5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  SOCS SOCS_box SH2 Motif Other DBs NCBI-GeneID:  101703084 NCBI-ProteinID:  XP_004839456 UniProt:  A0A0P6JWP7 LinkDB All DBs Position Un AA seq 536 aa AA seqDB search MDKVGKMWNTFKYKCQNLFGHEGGSHSENVDMNSNRCLPIKEKKISLVDSAPQQQSSPLR ENVALQLGLSPSKNSSRRNQNCATEIPQIVEISIEKDNDSCVTPGTRLTRRDSYSRHAPW GGKKKHSCSTKTQSSLDTDKKFGRARSGLQRRERRYGVSSVHDMDSVSSRTIGSRSLRQR LQDTVGLCFPMRTYTKQSKPLFSNKRKIHLSELMLEKCPFPAGSDLAQKWHLIKQHTAPV SPHSTFFDTFDPSLVSTEDEEDRLRERRRLSIEEGVDPPPNAQIHTFEATAQVNPLYKLG PKLAPGMTEMSGDSSAVPQGTCDSEEDTTTLCLQSRRQKQRQVSGDSHAHISRQGAWKVH TQIDYIHCLVPDLLQITGNPCYWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVSFR RYNRSLHARIEQWNHNFSFDAHDPCVFHSSTVTGLLEHYKDPSSCMFFEPLLTISLNRTF PFSLQYICRAVICRCTTYDGIDGLPLPSMLQDFLKEYHYKQKVRVRWLEREPVKAK NT seq 1611 nt NT seq  +upstreamnt  +downstreamnt atggataaagtggggaaaatgtggaataccttcaaatacaaatgtcagaatcttttcggt catgagggaggaagccatagtgaaaatgtggacatgaactccaacaggtgtttgcctatc aaagagaaaaagatcagtctggtagactctgctcctcagcagcaaagcagtcccttaaga gaaaatgttgccttacagctgggattaagtccttcaaagaattcttcaaggagaaaccaa aactgtgctactgaaatccctcaaattgttgaaataagcatcgagaaagataatgattca tgtgtcaccccaggaacaagactcacacgaagagattcctactctcgacatgccccatgg ggtgggaagaaaaagcattcctgttccacaaagacccagagttctttggacactgataaa aagtttggtagagctcgaagtggactgcaaaggcgagagaggcgctatggagtgagctca gtgcacgacatggacagtgtttccagcagaaccattgggagccgctctctgagacagagg ctacaggacaccgtgggcttgtgttttcccatgagaacttacaccaagcagtcaaagccc ctcttttccaataaaagaaaaatacatctttctgaattgatgcttgagaaatgccctttt cctgctggctcagatttagcccaaaaatggcatttgattaaacagcatacagctcctgtg agcccacattcaaccttttttgatacatttgatccgtccttggtttctacagaagatgaa gaagacagacttagagagagaagacggcttagtattgaagaaggggtggatccccctccc aatgcacaaatacatacatttgaagctactgcacaggttaatcccttatataaactggga ccaaagttagctcctggaatgacagaaatgagtggggacagttctgcagttccacagggt acttgtgactcagaagaggacacaaccaccctgtgtttgcagtcacggaggcagaagcag cgccaggtgtctggagacagccatgctcacattagcagacagggagcttggaaagtccat acacagattgattatatacactgccttgtgccggatttacttcagattacagggaatccc tgttactggggagtgatggatcggtatgaagcagaagcccttctggaagggaaacctgaa ggcacatttttgctcagggactctgcacaagaggactacctcttctctgtgagcttccgc cgctacaacagatccctgcatgcccgaattgaacagtggaatcacaacttcagttttgat gcccacgacccgtgtgtgtttcactcttctactgtaacaggacttctagaacattataaa gaccccagttcttgcatgttttttgaaccattgcttactatatctctgaataggaccttt ccttttagcctgcagtacatctgccgtgcagtcatctgcaggtgcactacgtatgatgga attgatgggctccctctaccgtcaatgttacaggattttttaaaggagtatcattataaa caaaaggttagggttcgctggttagaacgagaaccagtcaaggcaaagtaa

Heterocephalus glaber (naked mole rat): 101704157 Help Entry 101704157         CDS       T02812                                  Gene name Socs3 Definition (RefSeq) suppressor of cytokine signaling 3   KO K04696   suppressor of cytokine signaling 3 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04120   Ubiquitin mediated proteolysis hgl04380   Osteoclast differentiation hgl04630   JAK-STAT signaling pathway hgl04668   TNF signaling pathway hgl04910   Insulin signaling pathway hgl04917   Prolactin signaling pathway hgl04920   Adipocytokine signaling pathway hgl04930   Type II diabetes mellitus hgl04931   Insulin resistance hgl04932   Non-alcoholic fatty liver disease hgl04935   Growth hormone synthesis, secretion and action hgl05160   Hepatitis C hgl05164   Influenza A hgl05168   Herpes simplex virus 1 infection Brite KEGG Orthology (KO) [BR:hgl00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     101704157 (Socs3)  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101704157 (Socs3)    04668 TNF signaling pathway     101704157 (Socs3)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101704157 (Socs3)    04920 Adipocytokine signaling pathway     101704157 (Socs3)    04917 Prolactin signaling pathway     101704157 (Socs3)    04935 Growth hormone synthesis, secretion and action     101704157 (Socs3)   09158 Development and regeneration    04380 Osteoclast differentiation     101704157 (Socs3)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101704157 (Socs3)    04932 Non-alcoholic fatty liver disease     101704157 (Socs3)    04931 Insulin resistance     101704157 (Socs3)   09172 Infectious disease: viral    05160 Hepatitis C     101704157 (Socs3)    05164 Influenza A     101704157 (Socs3)    05168 Herpes simplex virus 1 infection     101704157 (Socs3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:hgl04121]     101704157 (Socs3) Ubiquitin system [BR:hgl04121]  Ubiquitin ligases (E3)   Multi subunit Ring-finger type E3    ECS complex     Target recognizing subunit (SOCS box)      101704157 (Socs3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  SH2 SOCS_box Motif Other DBs NCBI-GeneID:  101704157 NCBI-ProteinID:  XP_004860883 UniProt:  G5AVF0 LinkDB All DBs Position Un AA seq 226 aa AA seqDB search MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV LKLVHHYMPPPGASSSPPSEPSSPSEEPEQQPPAQPPPGSPPRKAYYIYSGGEKIPLVLS RPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL NT seq 681 nt NT seq  +upstreamnt  +downstreamnt atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag ttgcaggagagcggtttctactggagcgccgtgaccggcggcgaggcaaacctgctgctc agcgccgagccggccggcaccttcctcatccgcgacagctcggaccagcgccacttcttc acgctgagcgtcaagacccagtccgggacgaagaaccttcgcatccaatgcgagggtggc agcttctcgctccagagcgacccgcggagcacgcagcccgtgccccgcttcgactgcgtg ctcaaactggtgcaccactacatgccgccccccggcgcctcctcctcgcccccttccgaa ccctcctcgccctccgaggagcctgaacagcagccgcctgcccagccgcctccagggagc cctcccaggaaagcctattacatctactcggggggcgagaagatccccctggtgttgagc cggcccctctcctccaacgtggccacccttcagcatctctgtcggaagactgtcaatggg cacctggactcttacgagaaagtcacccagctgccggggcccatccgggagttcctggac cagtacgatgcgcccctttaa

Heterocephalus glaber (naked mole rat): 101704725 Help Entry 101704725         CDS       T02812                                  Gene name Socs4 Definition (RefSeq) suppressor of cytokine signaling 4   KO K04697   suppressor of cytokine signaling 4 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04630   JAK-STAT signaling pathway hgl04910   Insulin signaling pathway hgl04917   Prolactin signaling pathway hgl04930   Type II diabetes mellitus Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101704725 (Socs4)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101704725 (Socs4)    04917 Prolactin signaling pathway     101704725 (Socs4)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101704725 (Socs4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:hgl04121]     101704725 (Socs4) Ubiquitin system [BR:hgl04121]  Ubiquitin ligases (E3)   Multi subunit Ring-finger type E3    ECS complex     Target recognizing subunit (SOCS box)      101704725 (Socs4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  SOCS SOCS_box SH2 Motif Other DBs NCBI-GeneID:  101704725 NCBI-ProteinID:  XP_004835552 LinkDB All DBs Position Un AA seq 417 aa AA seqDB search MAESSDSSNKSADVRPKTSRSRSADRKDGYVWSGKKLSWSRRAEGPGAEVQDGDGDGERG PERKHSCSALELDLGHSCGQRFLGRSLKQKLQDAVGQCFPIKNCSSRHSPGLPSRRKIHI SELMLDKCPFPPRSDLAFRWHFIKRHTVPLSPKPDEWGRTDLAQRDLRAGQLPPSRAAAE APPCAPAPGCAASPASSSSVEDSDMDSDEDLVTLCASSRKRNKPKWEDEELLRLETPPKC HTQVDYVHCLVPDLLRINNNPCYWGVMDKYRAEALLEGKPEGTFLLRDSAQEDYLFSVSF RRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPGACMFFEPLLSTPLIRT FPFSLQHICRTVICNCTTYDGIDALPIPPPMKLYLKEYHYKSKVRVLRLDAPAASQC NT seq 1254 nt NT seq  +upstreamnt  +downstreamnt atggcagaaagtagtgacagtagtaataaaagcgcggacgtgaggcccaagacgagccgg agcaggagcgcggaccggaaggacggctacgtgtggagcggcaagaagctgtcgtggtcg cggagggccgagggcccgggtgccgaggtgcaggacggggacggcgacggcgagcggggc ccggagcggaagcacagctgctcggcgctcgagctggacctgggccactcgtgcgggcag cgcttccttggccgctctctgaagcagaagctgcaggacgccgtgggccagtgcttcccc atcaagaactgtagcagccgccactccccggggcttccgtcacggaggaagatccacatc agcgagctcatgctggataagtgtcctttcccaccgcgatcggacctggccttccggtgg cacttcatcaagcggcacaccgtgccgctgagtcccaagcccgacgagtggggccgcacg gacctcgcccagcgtgacctgcgggccggacagctgccgcccagcagagccgcggccgag gccccgccctgcgccccggcgcccggctgcgcagccagcccggcgtccagcagcagcgtg gaggacagcgacatggactcagacgaggacctcgtcacgctgtgcgccagctccaggaag aggaacaagcccaagtgggaggacgaggagctgctgcggctggagacaccgcccaagtgc cacacgcaggtggactacgtgcactgcctggtgcccgacctgctgcgcatcaacaacaac ccctgctactggggcgtgatggacaagtacagggccgaggcgctgctcgagggcaagccc gagggcaccttcctgctccgggactcagcgcaggaggactacctgttctccgtcagcttc cgccgctacagccgctcgctgcacgccaggatcgagcagtggaaccacaacttcagcttc gacgcgcacgacccctgcgtcttccactcccccgacatcaccgggctgttggagcactac aaggaccccggcgcctgcatgttcttcgagcccctcctgtccacgccgctcattcggact ttccccttctccctgcagcacatctgcaggacagtcatctgcaactgtaccacctatgac ggcatcgacgccctgcccatccctccgcccatgaagctgtacctgaaggagtatcattac aaatcaaaggtcagagtcctcaggctcgacgcgcccgcggccagccagtgctag

Heterocephalus glaber (naked mole rat): 101706091 Help Entry 101706091         CDS       T02812                                  Definition (RefSeq) suppressor of cytokine signaling 6   KO K04699   suppressor of cytokine signaling 6/7 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04630   JAK-STAT signaling pathway hgl04917   Prolactin signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101706091  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     101706091  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:hgl04121]     101706091 Ubiquitin system [BR:hgl04121]  Ubiquitin ligases (E3)   Multi subunit Ring-finger type E3    ECS complex     Target recognizing subunit (SOCS box)      101706091 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  SH2 SOCS_box Motif Other DBs NCBI-GeneID:  101706091 NCBI-ProteinID:  XP_004861473 LinkDB All DBs Position Un AA seq 537 aa AA seqDB search MKKISLKTFRKSFNLSKSKEETDFMVVQQPSIASDFGKDDALFGSCYGKDMASCDINSED EKGGKNRSKSESLMGTLKRWLSSKQKPKGKGSTPSGSCADEDTFSSSSAPMVFKDVRVKK PIRSTSLRSQHYTHTPWPRGPTNSEETYIKTEVRVKALVHSSSPSPALNAVRKDFHDLQS ETVCQEQNNSLKSSDSPNGDLHFHLDEHVPVVIERKPQDYIQYTVPLDERMYPLEGSRSY CLNSSLPMEVSAVPPQVGGSSFAEDENEVNQDLVVAPEIFVDQSVNGLLIGITGVMLQSP RASRDDVPPLSPLVPTMQNNQIQRNFSGLTGTDAHVAESMCCHLNFDPYPNSAPGVARVY DSVQSSGPRVVASLTEELKKLAKQGWYWGPLTRWEAEGKLANLPDGSFLVRDSSDDHYLL SLSFRSHGKTLHTRIEHSNGRFSFYEQPDVEGHRSIVDLIKHSIRDSENGAFCYSRSPLP GSATYPVRLTSPVSRFMQVRSLQYLCRFVIRQYTRIDLIQKLPLPNKMKDYLQEKHY NT seq 1614 nt NT seq  +upstreamnt  +downstreamnt atgaagaaaattagtcttaaaaccttccggaagtcttttaacttgagtaaaagtaaagaa gaaactgatttcatggtagtacaacaaccatcaatagccagtgactttggaaaagatgat gccttgtttggtagctgctatggtaaagatatggccagctgtgatatcaacagtgaagat gaaaaaggtgggaaaaacagatcaaaaagtgagagcctgatgggaaccttaaaaaggtgg ctttcttctaagcagaagccaaagggcaagggcagcacaccgtcaggaagctgtgccgat gaggacaccttctcctcctcctcagcccccatggtcttcaaagatgtcagagtgaaaaag ccaatcaggtctacttccctccgcagtcagcactacacccacacgccctggcctcgcggg cccacaaactccgaggagacttacatcaaaacggaggtcagggtcaaagccttggttcac tcttccagcccaagtcctgcactgaatgctgttcgaaaggattttcatgaccttcagtct gaaactgtatgccaagagcaaaataattctcttaagagttctgattctcccaatggagat ttgcatttccacctggatgaacatgtgcctgtagttattgaacgtaagccccaggactac attcagtatactgtgcctttagacgagaggatgtatcctttggaaggatcacgtagctat tgtctgaacagttctttgcccatggaggtctctgcagttcctcctcaagtgggagggagc tcttttgctgaagatgagaatgaggtaaaccaggacctagttgttgccccagagatcttt gtggatcagtctgtgaatggcttgttgattggcatcacgggagtcatgttgcagagcccc agagcaagtcgtgatgatgtccctccactttcacctttggtacctacaatgcagaataat caaatccaaaggaacttcagtggactcactggcacagatgcccacgtggctgaaagtatg tgttgtcatttgaattttgatccataccctaactctgctcctggggttgcaagagtttat gattcagtgcagagtagtggtcccagggttgtggcaagccttacagaggagctgaagaaa cttgcaaaacaaggatggtactggggaccactcacacgctgggaggcagaagggaaacta gcaaacttgccagatggttcttttcttgttcgggatagttctgatgatcattatctttta agcttgagctttcgttcccatggtaaaacacttcacactagaattgagcactcaaatggt aggtttagcttttatgaacaaccagatgtggaagggcacagatctatagttgatctaatt aagcattcaatcagggactctgaaaatggagctttttgttattcgaggtctccattgccc ggatctgcaacttaccctgtcagactgaccagtccagtgtcacggttcatgcaggtgcgt tctttgcagtacctgtgtcgttttgttatacgtcagtataccagaatagacttaattcag aaactgcctttgccaaacaaaatgaaggattatttacaggagaagcactactga

Heterocephalus glaber (naked mole rat): 101716336 Help Entry 101716336         CDS       T02812                                  Gene name Socs6 Definition (RefSeq) suppressor of cytokine signaling 6   KO K04699   suppressor of cytokine signaling 6/7 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04630   JAK-STAT signaling pathway hgl04917   Prolactin signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101716336 (Socs6)  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     101716336 (Socs6)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:hgl04121]     101716336 (Socs6) Ubiquitin system [BR:hgl04121]  Ubiquitin ligases (E3)   Multi subunit Ring-finger type E3    ECS complex     Target recognizing subunit (SOCS box)      101716336 (Socs6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  SH2 SOCS_box Motif Other DBs NCBI-GeneID:  101716336 NCBI-ProteinID:  XP_004862027 LinkDB All DBs Position Un AA seq 535 aa AA seqDB search MKKISLKTFRKSFNLSKSKEETDFMVVQQPSIASDFGKDDALFGSCYGKDMASCDINSED DKGGKNRSKSESLMGTLKRRLSSKQKPKGKGSTPSGSCADEDTFSSSSAPIVFKDVRAQR PIRSTSLRSHHYSPTPWPLRPTNSEETCIKMEVRVKALVHSSSPSPALNGVRKDFRDLQS ETVCQEQNNSLKSSDSPNGDLHLHLDEHVPVVIGLMPQDYIQYTVPLDEGMYPLEGSRSY CLDSSSPMEVSAVPPQVGGSSFAEDENQVDQDLVVAPEIFVDQSVNGLLIGTTGVMLQSP RASHDDVPPLSPLLPPMQNNQIQRNFSGLTGTDAHVAESMRCHLNFDPNSAPGVARVYDS VQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSL SFRSHGKTLHTRIEHSNGRFSFYEQPDVEGHTSIVDLIEHSIRDSENGAFCYSRSRLPGS ATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLIQKLPLPNKMKDYLQEKHY NT seq 1608 nt NT seq  +upstreamnt  +downstreamnt atgaagaaaattagtcttaaaaccttccgaaagtcttttaacttgagtaaaagtaaagaa gaaactgatttcatggtagtacaacaaccatcaatagccagtgactttggaaaagatgat gccttgtttggtagctgctatggtaaagatatggccagctgtgatatcaatagtgaagat gacaaaggtgggaaaaacagatcaaaaagtgagagcctgatgggaaccttaaaaaggcgg ctttcttctaagcagaagccaaagggcaagggcagcacaccgtcaggaagctgtgccgat gaggacaccttctcctcctcctcagcccccatcgtcttcaaagatgtcagagcgcaaagg ccgatcaggtccacttccctccgcagtcatcactacagccccacgccctggcctctccgg cccacaaactccgaggagacatgcatcaaaatggaggtcagagtcaaagccttggttcac tcttccagcccgagtcctgcattgaatggtgttcgaaaggattttcgtgaccttcagtct gaaactgtatgccaagagcaaaataattctcttaaaagttctgattctcccaatggagat ttacatctccacctggatgaacatgtgcctgtagttattggacttatgcctcaggactac attcagtataccgtgcctttagacgaggggatgtatcctttggaaggatcacgtagctat tgtctggacagttcttcacccatggaggtctctgcggttcctcctcaagtgggagggagc tcttttgctgaagatgagaatcaggtagaccaggacctagttgttgccccagagatcttt gtggatcagtctgtgaatggtttgttgattggcaccacgggagtcatgttgcagagcccc agagcaagtcatgatgatgtccctccactttcacctttgctacctccaatgcagaataat caaatccaaaggaacttcagtggactcactggcacagatgcccatgtggctgaaagtatg cgttgtcatttgaattttgatcctaattctgctcctggggttgcacgagtttatgactca gtgcagagtagtggtcccatggttgtgacaagccttacagaggagctgaagaaacttgca aaacaaggatggtactggggaccgatcacacgctgggaggcagaagggaaactagcaaat gtgccagatggttcttttcttgttcgggatagttctgatgatcgttatcttttaagcttg agctttcgttcccatggtaaaacacttcacactagaattgagcactcaaatggtaggttt agcttttatgaacaaccagatgtggaaggacatacatctatagttgatctaattgagcat tcaatcagggactctgaaaatggagctttttgttattcgaggtctcggttgcctggatct gcaacttaccctgtcagactgaccaatccagtgtcacggttcatgcaggtgcgttctttg cagtacctgtgtcgttttgttatacgtcagtataccagaatagacttaattcagaaactg cctttgccaaacaaaatgaaggattatttacaggagaagcactactga

Heterocephalus glaber (naked mole rat): 101716580 Help Entry 101716580         CDS       T02812                                  Gene name Socs2 Definition (RefSeq) suppressor of cytokine signaling 2   KO K04695   suppressor of cytokine signaling 2 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04630   JAK-STAT signaling pathway hgl04910   Insulin signaling pathway hgl04917   Prolactin signaling pathway hgl04930   Type II diabetes mellitus hgl04935   Growth hormone synthesis, secretion and action Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101716580 (Socs2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101716580 (Socs2)    04917 Prolactin signaling pathway     101716580 (Socs2)    04935 Growth hormone synthesis, secretion and action     101716580 (Socs2)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101716580 (Socs2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:hgl04121]     101716580 (Socs2) Ubiquitin system [BR:hgl04121]  Ubiquitin ligases (E3)   Multi subunit Ring-finger type E3    ECS complex     Target recognizing subunit (SOCS box)      101716580 (Socs2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  SOCS_box SH2 SH2_2 Condensation Motif Other DBs NCBI-GeneID:  101716580 NCBI-ProteinID:  XP_004845017 LinkDB All DBs Position Un AA seq 198 aa AA seqDB search MTLRCLEPSGNGAEGAHSQWGTSGSAEEPSPEAARLAKALRELGYTGWYWGNMTVNEAKE KLKEAPEGTFLIRDSSHSGYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFD SVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPSLQHLCRLTINKCTGTVWG LPLPTRLKDYLEEYKFQV NT seq 597 nt NT seq  +upstreamnt  +downstreamnt atgaccctgcggtgcctcgagccctccgggaatggtgcggaaggggcgcacagccagtgg gggacctcggggtcggccgaggagccgtccccggaggccgcgcgtctggccaaggccctg cgcgagctcggctacacaggatggtactggggaaatatgactgttaatgaagccaaagag aaattaaaagaagcaccagaaggaactttcttgattcgagatagttcgcattcaggctac ctgctaacaatatctgttaaaacatcagctggaccaactaatctgcgaattgagtaccaa gatgggaagttcagactggattctatcatatgtgtcaagtccaagcttaaacagttcgac agtgtggttcacctgattgactactatgtccagatgtgtaaggataagcggacgggcccg gaagctccccgaaacgggaccgttcacctttacctgaccaaaccgctgtacacatcagca ccctccctgcagcacctctgtcgactcaccattaacaaatgcaccggtactgtctgggga ctgcctttaccaacaagactcaaagattacttggaagaatataaattccaggtgtaa

Heterocephalus glaber (naked mole rat): 101723330 Help Entry 101723330         CDS       T02812                                  Gene name Socs1 Definition (RefSeq) suppressor of cytokine signaling 1   KO K04694   suppressor of cytokine signaling 1 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04120   Ubiquitin mediated proteolysis hgl04380   Osteoclast differentiation hgl04630   JAK-STAT signaling pathway hgl04910   Insulin signaling pathway hgl04917   Prolactin signaling pathway hgl04930   Type II diabetes mellitus hgl04935   Growth hormone synthesis, secretion and action hgl05145   Toxoplasmosis hgl05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     101723330 (Socs1)  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101723330 (Socs1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101723330 (Socs1)    04917 Prolactin signaling pathway     101723330 (Socs1)    04935 Growth hormone synthesis, secretion and action     101723330 (Socs1)   09158 Development and regeneration    04380 Osteoclast differentiation     101723330 (Socs1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     101723330 (Socs1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101723330 (Socs1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     101723330 (Socs1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:hgl04121]     101723330 (Socs1) Ubiquitin system [BR:hgl04121]  Ubiquitin ligases (E3)   Multi subunit Ring-finger type E3    ECS complex     Target recognizing subunit (SOCS box)      101723330 (Socs1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  SH2 SOCS_box Motif Other DBs NCBI-GeneID:  101723330 NCBI-ProteinID:  XP_004864951 LinkDB All DBs Position Un AA seq 211 aa AA seqDB search MVAHNQVAADNAISTAAEPRRRPEPSSSPSSSPAAPARPRPCLAAPAPTPGDTHFRTFRS HADYRRITRTSALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMA SGPTSIRVHFQAGRFHLDGSRESFDCLFELLEHYVAAPRRMLGTPLRQRRVRPLQELCRQ RIVATVGRENLARIPLNPVLRDYLSSFPFQI NT seq 636 nt NT seq  +upstreamnt  +downstreamnt atggtagcacacaaccaggtggcagccgacaatgcaatctccacggcagcagagccccga cggcggccagagccttcctcctctccctcctcctcgcccgcggcccccgcgcgccctcgg ccctgcctggcggccccggccccgacccccggagatacacacttccgcacgttccgctct cacgcggattaccggcgcatcacgcgcacgagcgcgctcctcgacgcttgcggcttctac tggggacccctgagcgtgcacggggcgcacgagcggctgcgagccgagcccgtgggcacc ttcctggtgcgcgacagtcgccagcggaactgcttcttcgccctcagcgtgaagatggcc tcgggccccacgagcatccgcgtgcacttccaggccggccgcttccacctggacggtagc cgcgagagcttcgactgcctcttcgagctgctggagcactacgtggcggcgccgcgccgc atgctgggcaccccgctgcgtcagcgccgcgtgcgccccctgcaggagctgtgccgccag cgcatcgtggccaccgtgggccgcgagaacctggcgcgcatccctctcaaccccgtcctc cgagactacctgagctccttccccttccagatctga

Heterocephalus glaber (naked mole rat): 101725097 Help Entry 101725097         CDS       T02812                                  Gene name Socs7 Definition (RefSeq) suppressor of cytokine signaling 7   KO K04699   suppressor of cytokine signaling 6/7 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04630   JAK-STAT signaling pathway hgl04917   Prolactin signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101725097 (Socs7)  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     101725097 (Socs7)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:hgl04121]     101725097 (Socs7) Ubiquitin system [BR:hgl04121]  Ubiquitin ligases (E3)   Multi subunit Ring-finger type E3    ECS complex     Target recognizing subunit (SOCS box)      101725097 (Socs7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  SOCS_box SH2 Motif Other DBs NCBI-GeneID:  101725097 NCBI-ProteinID:  XP_004859609 LinkDB All DBs Position Un AA seq 573 aa AA seqDB search MVFRNVGRPPEDEDAEAAPGPGPTELLCPRHRCALDPKALPPGLALEQAWGPAAGLEAQL AALGLGQPAGPGGKAAGGGCCPCPCPAQPPAPQPPPPAAAPQAGEDPTETSDALLVLEGL ESEAESLETNSCSEEELSSPGRGGGGGGRLVLQPSGPDLPPALFPLQDLVPSGRPSRAEQ QPPPPPAGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELATSAASL TDVGCSAGREVDSGRKPRLTRTQSAFSPASFSPLFTGETVSLVDVDISQRGLSSPHPPTP PPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRATESL HSQPPQHLQCPLDRPDSSSFTASLRELEQCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSS DPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFL YFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYI RKFYYYDPQEEVYLSLKEAQLISRQKQEVEPST NT seq 1722 nt NT seq  +upstreamnt  +downstreamnt atggtgttccgcaacgtggggcggccgccggaggacgaggacgcggaggcggcgccgggc ccgggacccacggagctgctgtgtccgcggcaccgctgcgccctggaccccaaggccctg ccgccgggcttggcgctcgagcaggcctggggcccggccgcgggactggaggcgcagctg gcggccctggggctcgggcagccggcgggcccggggggcaaggcagctggcgggggctgc tgcccgtgcccttgccccgcgcagccgcctgctccgcagcccccgccgccggccgccgcc ccgcaggccggggaggaccccacggagacgagtgacgcgctgctggtgctggagggctta gagtcggaggctgagagcctggaaaccaacagctgctcggaagaggagctcagcagcccg ggccgcggaggaggagggggcggccggctggtgctgcagccctcgggccccgatctgccc ccagcgctcttcccgctgcaggacttggtcccttcggggcggccgagccgagccgagcag cagccgccgccgccgcccgctgggcctctccggcccctcgcgggcccctctcggaagggc tccttcaagatccgcctcagccgcctcttccgcacgaagagctgcaacggcggctcgggc ggcggggacgggaccggcaagaggccttctggagagctggccacctcagccgcgagcctc accgacgtgggatgctctgcgggtcgggaggtggactcggggaggaaacccaggttgaca agaactcaaagtgccttttctccggcctccttcagccccctgttcacaggtgaaacagtg tcgcttgtggacgtggacatttctcagcggggcctgagctccccacaccctccaactccc cctcctcctccgagaagaagcctcagcctcctagatgatatcagtgggacgctgcctaca tctgtccttgtggctccgatggggtcttccctgcagtccttcccccttcctccgcctcct ccgccccatgccccagatgcatttccccggattgctcccatccgagccaccgagtccctg cacagccagcccccccagcacctgcagtgtcccctcgaccggccggactcgagcagcttc acggccagccttcgagagctggagcagtgtggttggtattgggggccaatgaattgggag gatgcagagatgaagctgaaagggaagccggatggttctttcctggtgcgagacagctcc gaccctcggtacatcctgagcctcagtttccggtcccagggcatcactcaccacactagg atggagcactaccgaggaacctttagcctgtggtgccatcccaagtttgaggatcgctgt cagtccgtggtggagttcatcaagagagccatcatgcactccaagaacgggaagttcctc tacttcctgagatccagggttccagggctgcctcccacgccagttcagctgctctacccc gtgtcccgattcagcaatgtcaagtccctccagcacctttgccgattccggatccgacag ctcgtgcggatagatcacatcccggatctcccattgcctaaacctctgatctcttatatc cgaaagttctactactatgatcctcaggaagaggtatacctttcgctaaaggaagcgcag ctcatttccagacagaagcaggaggtggaaccctccacgtag

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