KEGG   Heterocephalus glaber (naked mole rat): 101708442Help
Entry
101708442         CDS       T02812                                 

Gene name
Hdac6
Definition
(RefSeq) histone deacetylase 6
  KO
K11407  histone deacetylase 6 [EC:3.5.1.98]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl05034  Alcoholism
hgl05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09160 Human Diseases
  09161 Cancers: Overview
   05203 Viral carcinogenesis
    101708442 (Hdac6)
  09165 Substance dependence
   05034 Alcoholism
    101708442 (Hdac6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hgl01009]
    101708442 (Hdac6)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hgl03019]
    101708442 (Hdac6)
   04131 Membrane trafficking [BR:hgl04131]
    101708442 (Hdac6)
   03036 Chromosome and associated proteins [BR:hgl03036]
    101708442 (Hdac6)
Enzymes [BR:hgl01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     101708442 (Hdac6)
Protein phosphatases and associated proteins [BR:hgl01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     101708442 (Hdac6)
Messenger RNA biogenesis [BR:hgl03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     101708442 (Hdac6)
Membrane trafficking [BR:hgl04131]
 Autophagy
  Aggrephagy
   Other aggrephagy associated proteins
    101708442 (Hdac6)
Chromosome and associated proteins [BR:hgl03036]
 Eukaryotic Type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class II HDACs
     101708442 (Hdac6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Hist_deacetyl zf-UBP zf-UBP_var
Motif
Other DBs
NCBI-GeneID: 101708442
NCBI-ProteinID: XP_012923668
LinkDB All DBs
Position
Un
AA seq 1101 aa AA seqDB search
MTSTGQDSTTTRLRRSRHNPQSPLHDSSVTWKRSIKKGAVPRSSPSLAEVKKKGKMKKLG
QAAEDDLIMGLQGLDMNPEAKVLVGTGLVFDEQLNEFHCLWDDSFPERPERLHAIKEQLI
QEGLLDRCVSFQARFAEKEELMLVHSLEFIDLMETTQHMNERELRLLADTYDSVYLHPNS
YTCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQK
KHRIQRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
QGYTINVPWNQVGMRDADYIAAFLHILLPVAFEFQPQLVLVAAGFDAIQGDPKGEMATTP
AGFAQLTHLLMGLAGGKLILSLEGGYNLRSLAEGVSASLHILLGDPCPMLESPGAPCPSA
QASISSTLEALEPFWEVLVRPAETPEEDSVAEDGVQEIQEEGPWEPPVLPILTWPLLQAR
TGLIYDERMMSHCNLWDSHHPETPQRILRIMCHLEELGLAGRCVTLPVRPATEAELLTCH
SAEYVERLRATEKMKTRELHREGANFDSIYICPSTFTCAQLATGSACRLVEAVLSGEVLN
GVAVVRPPGHHAEQDTACGFCFFNSVAVAARHAQAISGHAMRILIVDWDIHHGNGTQHIF
EDDPSVLYVSLHRFDRGTFFPMGDEGASSQVGKAAGTGFTVNVAWNGPRVGDAEYLAAWH
RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLANGRIILILEG
GYNLTSISESMAACTHALLGDLSPQLALLRPPQSGALASITETIQVHRRYWRSLRVTRKV
LEAGMRKPTSALSTEESSPGQTKPEAAKVVLTRDQSSETATGRATLEKGPSASEDAVGGA
ELNQTPQASCTEKQTSAASPVPGATALLPPSQLTGNPKTLELGKEALETLEPQALGEESL
LGEAAGGQDVDDSQLTQGFQDLADTNQDILHAVTPLLWCPHLVAVRPMSAANLDVTQPCK
DCGTLQENWLCLSCYQVYCSRYVNAHMVRHHEVSGHPLVLSYIDLSTWCYPCQAYVHHQD
LLDVKNITHQKKFGEDMPHPH
NT seq 3306 nt NT seq  +upstreamnt  +downstreamnt
atgacctccaccggccaagattccaccacaaccaggcttcgaaggagtaggcacaacccc
cagtcgccccttcacgactccagtgtcacttggaagcgaagtattaagaagggtgctgta
ccccgctccagccccagtctagcagaggtgaagaagaagggcaaaatgaagaaactcggt
caagcagcggaagatgacctaatcatgggtcttcaagggctggatatgaaccctgaggcc
aaggtccttgttggcactgggctggtgttcgatgagcagctaaatgaattccattgcctc
tgggatgacagcttccctgaacgtcctgagcggctccatgccatcaaggagcagctgatc
caggaagggctcctggatcgctgtgtgtcctttcaggcccgctttgctgaaaaggaagag
ctgatgttggttcacagcctagaatttattgacctgatggaaacgacccagcatatgaat
gagagagaactccgactactagcggatacctatgactcagtttatctgcatccgaactct
tacacctgtgcctgcctggcctcaggctctgtccttaggctggtggatgcggtcctgggt
gctgagatacggaatggcatggccatcatcaggcctcctggacaccacgcccagcacagt
cttatggatgggtattgcatgttcaaccatgtggctgtggctgcccgctacgctcaaaag
aagcaccgcattcagagggtccttattgtggactgggatgtgcaccatggtcaaggaaca
cagttcacttttgatcaggaccccagtgtcctctatttttccatccatcgttatgagcag
ggtcggttctggccccaccttaaggcctctaactggtctactactggttttggccagggt
caaggttacaccatcaatgtgccttggaaccaggtggggatgcgggacgctgactacatt
gctgcttttctgcacatcctgctaccagttgcctttgagttccagcctcagctggtccta
gtggctgctggatttgatgccatacaaggggatcccaagggtgagatggccaccactccg
gcagggttcgcccagctaacccacttgctcatgggtctggcaggaggcaagctgatcctg
tctctggagggtggctacaaccttcgctccctggctgagggcgtcagtgcatcactccac
atccttctgggagatccttgccccatgctggagtcccccggtgccccctgccccagtgcc
caggcttcaatctcctccactctggaagcccttgagcctttctgggaggttcttgtgaga
ccagcagagaccccagaggaggacagtgtagcggaggatggtgtgcaggagatccaggag
gaaggaccctgggaaccccctgtgctgccaatcctgacctggcccttgctacaggcacga
actgggctgatttatgacgagcggatgatgagtcactgcaacttatgggacagccaccac
cctgagacaccccagcgcatcctgcggatcatgtgccacctggaggagctgggccttgcc
gggcgctgcgtcaccctgcctgtgcggcctgccacggaggcggagttgctcacctgccac
agtgccgaatatgtggagcgcctccgagcaactgagaagatgaaaacccgagagctgcac
cgggagggcgccaactttgactccatctacatctgccccagcaccttcacctgtgcacag
cttgctacgggctctgcctgccgccttgtggaggctgtgctctcaggagaggttctgaat
ggtgtggccgtggttcgccccccagggcaccatgcagagcaggacactgcctgcggtttc
tgctttttcaactctgtggctgtggctgctcgccatgcccaggccatcagtgggcatgcc
atgcgaatcctgatcgtggattgggacatccatcatggtaatggaactcagcacatattt
gaggatgaccccagcgtgttatatgtgtccctgcaccgctttgaccgaggcaccttcttt
cccatgggggacgagggtgccagcagccaggtgggcaaggctgcaggcacaggcttcacc
gtcaatgtggcctggaatgggccccgagtgggtgatgctgagtacctggctgcctggcat
cgcctggtgcttcccattgcctatgagtttaacccggaactggtactggtctcagctggc
tttgatgcggcacgaggggacccactagggggctgccaggtgtcacccgaaggttatgcc
catctcacccacctgttgatgggccttgccaatggtcgcatcatccttatcctagagggt
ggctacaatctgacatccatctcagaatccatggctgcctgtactcacgcacttcttgga
gacctgtcaccccagctggctctgctgcggcctccacagtctggggctctggcctccatc
actgagaccatccaagtccatcgaagatactggcgcagcttacgagtcacaaggaaggtt
ctggaagcaggcatgaggaagccaacctcagcattatctacagaagagtccagtccaggc
cagactaaaccagaggcagctaaagtggtgctcactcgggaccagtcctcagagacagcc
actggaagagccaccctggagaaaggcccatcagcctcagaggacgctgtgggaggagct
gagctgaaccaaactcctcaagcctcatgtacagaaaagcagacctcggcagcctcacct
gtgccaggagccacagccctgctccctcccagtcagctgactgggaatcctaagaccttg
gaactaggcaaggaagctctggagaccctggaacctcaggcccttggagaggagagccta
ctaggagaggcagctggaggtcaggatgtggatgactcacagctgacacagggatttcag
gaccttgctgacactaaccaggacatattacatgctgtgacaccactgctctggtgtccc
catctggtagcagtacgccccatgtctgcagcaaacctggacgtgacccaaccctgtaag
gactgtggaacactccaggagaactggttgtgtttgtcctgctatcaggtctactgcagt
cgttatgtcaacgctcatatggtccgacaccacgaagtatctggacacccgctagtcctc
agctacatcgatttgtctacctggtgttacccttgtcaggcctatgtccaccaccaggat
ctcctagatgtgaagaacatcacccatcagaagaagtttggggaggacatgcctcaccca
cactaa

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