KEGG   Heterocephalus glaber (naked mole rat): 101709487Help
Entry
101709487         CDS       T02812                                 

Gene name
Nsd2, Whsc1
Definition
(RefSeq) nuclear receptor binding SET domain protein 2
  KO
K11424  histone-lysine N-methyltransferase NSD2 [EC:2.1.1.43]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl00310  Lysine degradation
hgl05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:hgl00001]
 Metabolism
  Amino acid metabolism
   00310 Lysine degradation
    101709487 (Nsd2)
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    101709487 (Nsd2)
Enzymes [BR:hgl01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     101709487 (Nsd2)
Chromosome and associated proteins [BR:hgl03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     101709487 (Nsd2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PWWP SET PHD HMG_box HMG_box_2 zf-HC5HC2H zf-HC5HC2H_2
Motif
Other DBs
NCBI-GeneID: 101709487
NCBI-ProteinID: XP_004847458
LinkDB All DBs
Position
Un
AA seq 1366 aa AA seqDB search
MEFSIKKSSLSVQKVVKCIKMKQAPEILGNTNGKTQNCEMNRDCSVFLSKAQLSNSLQEG
VMQKFNGHDALPFIPAEKLKDLTSCVFNGEPGAPDAKLCFESQEGKGIGTPPNTTPIKNG
SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEEDGPKSESKVRRSRKRSIKYDSLLE
QGLVEAALVSKISSPADKKIPVKKESCPNTGRDKDHLLKYSVGDLVWSKVSGYPWWPCMV
SADPLLHNHTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESARQ
APTKAEKIKLLKPISGKLRAQWEMGIIQAEEAASLSVEERKAKFTFLYVGDQLHLNPQVA
KEAGIAAEGSGEVVEPAGVGEAAAADPQAAQEEGIPMKRRRRAKRSSSVENHESDACVEK
STPQKPTEAEPKRGVGSPPGRKKAAASTPRSRKGGAASQFLVFCQKHRDEVVAEHPDASG
EEIEELLGSQWNMLNEKQKARYNTKFALVTSAPSEEDPGNVNGKKRNHTKRTEDPPEDVD
IEDAPRKRLRTDKHGLRKRETSTDKMARTSSYKATEAAASLKSQAATKNLSDACKPLKKR
NRASAAASSTLGFSKSSSPSASLTENEVSDGPGDEPSESPYESADETQTEVSVSSKRSER
GVAAKKEYVCQLCEKTGSLLLCEGPCCSAFHLACLGLSRRPEGRFTCSQCTSGIHACFVC
KERKAEVKRCVVTQCGKFYHDACVRRYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG
KMMRCVRCPVAYHGGDACLAAGCSVIASHSIVCTAHFTARKEKRHHSHVNVSWCFVCSKG
GSLLCCEACPAAFHPDCLNIDMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH
PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYHGVRGIGRVFKN
ALQEAEARFREVKLQREARETQESERRPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP
TDENPCGFDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQYPETKIIKTDGKGWGLVAK
RDIRKGEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM
NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG
FLGDRPKTSASLSSEEKGKKTKKKTRRRRAKGEWKRQSEDECFRCGDGGQLVLCDRKLCT
KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSMSFCHLCPNSLCKEHQDGASFRTAQDGQ
TYCCEHDLGAQAGLRSGKAEKPLPEPVKSKGKRRKRRCWRRVTEGK
NT seq 4101 nt NT seq  +upstreamnt  +downstreamnt
atggaatttagtatcaaaaaaagttctctttctgtgcaaaaagttgtaaagtgcataaag
atgaagcaggcaccagaaatccttggcaatacaaatggaaagactcagaactgtgaaatg
aatcgcgactgttctgtattcctcagcaaagctcagctttctaacagcctacaggagggg
gtcatgcagaagtttaatggccacgatgcacttccctttattccagcagagaagttgaag
gatcttacttcctgtgtgttcaatggagaacctggtgctcccgatgccaaattgtgtttt
gagtcccaggaaggaaaaggaattgggacaccgcccaacactacccctatcaaaaatggc
tctccagaaatcaagctgaaaatcaccaaaacatacatgaatgggaaacctctctttgaa
tcttctatctgtggtgacagtgctgctgatgtgtctcagtcagaagaagatgggccgaag
tcggagagcaaggtgcggaggagcaggaaaaggagcataaagtacgactccttgctggag
cagggccttgtggaagcagctctggtgtccaagatctcgagtcctgcagataaaaagatt
ccagttaagaaagagtcctgcccaaacactggcagagacaaagaccacctgttgaaatac
agcgtgggtgacttggtgtggtccaaagtgtcgggttacccttggtggccttgcatggtt
tctgccgatccactccttcacaaccacaccaaacttaaaggtcagaaaaagagtgcacgc
cagtatcacgtccagttctttggtgatgccccagaaagagcatggatatttgagaagagc
cttgtggcttttgaaggagaaggccagtttgagaagttatgccaggaaagtgccaggcag
gcacccacgaaagctgagaaaatcaagctgttgaaacctatttcagggaaactgagggct
cagtgggagatgggcatcattcaggcggaggaagctgccagcctgtctgtggaagagcgg
aaagccaagttcaccttcctctatgtgggggaccagctgcacctcaacccccaggtagcc
aaggaggccggcattgctgctgagggctctggagaagtggtggagcctgccggggttggg
gaagcagctgctgcagaccctcaggctgctcaggaggagggcattcccatgaagaggagg
cggagagccaagcggtctagctctgtcgagaaccacgagagtgatgcctgcgtggagaag
agcactccacaaaagcccaccgaggccgagcccaaaagaggagtcgggtctccccctggg
aggaagaaggcagcagcctccactccaaggagccggaagggaggtgcggcgtctcagttt
ttggtcttctgtcaaaagcaccgggatgaggttgttgctgagcacccagatgcatcaggc
gaggagattgaagaactgctgggatcccagtggaatatgctcaatgaaaaacagaaagct
cgctataacaccaagtttgcccttgtgacctcagccccatctgaagaagatcccggtaat
gtaaatgggaaaaaaagaaatcatacaaagaggacagaggaccctccagaagatgttgac
atcgaggatgcacctagaaagagactcaggaccgacaagcatggtcttcggaagagagag
acaagcactgacaagatggccaggacaagctcttacaaggccacggaggcggctgcctca
ctcaagagccaggcagcaacaaaaaatctgtctgatgcgtgcaaaccactgaagaagcga
aatcgggcttctgcagcagcgtcttccactcttgggtttagcaaaagttcatctccttct
gcatccttaactgagaatgaggtctcagacggcccaggagacgagccctcggagtcccct
tacgaaagtgcggatgaaacacagactgaagtgtccgtctcgtctaaaaggtctgaacga
ggagtggccgccaaaaaggagtatgtgtgccagctgtgcgagaagacgggaagcctcctg
ctgtgcgaaggcccttgctgcagtgcattccacctcgcctgcctcgggctttccaggaga
ccagaggggaggttcacctgcagccagtgcacctcagggatccacgcgtgctttgtgtgc
aaggagaggaaggcggaggtgaagcgctgtgtcgtgacccagtgtgggaaattctaccac
gacgcctgtgtgagaagataccctctcactgtgtttgaaagcaggggctttcgctgcccc
ctgcatagctgcgtgagctgccacgcctcaaacccttcaaacccacggccctcaaaaggt
aaaatgatgcggtgcgtgcgctgccccgtagcatatcacggaggggacgcatgtctggca
gcaggctgctcggtgatcgcttcccacagcatcgtctgcacggcccacttcactgctcgg
aaggagaagcggcaccacagccacgtgaatgtgagctggtgcttcgtgtgctctaaaggg
gggagcctcctgtgctgcgaggcctgcccggcagccttccaccccgactgcctgaacatc
gacatgcctgacggcagctggttctgcaacgactgcagggctgggaagaagctgcacttc
caagacatcatctgggtcaaactcgggaactacagatggtggccggcagaagtttgccat
cccaaaaatgtccccccaaatattcagaaaatgaagcacgagattggagaattccctgtg
tttttctttgggtctaaagattattactggacgcatcaggcacgagtattcccgtacatg
gagggggaccggggcagccgctaccatggggtcagagggatcggaagagtcttcaaaaac
gcactgcaagaagctgaagctcgttttcgtgaagtcaaacttcagagggaagcccgagaa
acacaggagagcgagcgcaggcccccaccctacaagcacatcaaggtcaataagccttac
gggaaagttcagatctacacggccgatatctcggaaatcccaaagtgtaattgtaagccc
acagacgagaatccctgtggctttgactcagaatgtttgaacaggatgctgatgttcgag
tgccacccgcaggtgtgtcccgcgggcgagtactgccagaaccagtgcttcaccaagcgc
cagtacccagagaccaagatcatcaagacagatggcaaagggtggggcctggttgccaag
cgagacatcagaaagggagagtttgtgaatgagtatgtcggtgagctgattgatgaggag
gagtgtatggcaaggatcaagtacgcacacgagaacgacatcacgcacttttacatgctc
accatagacaaggaccgtataatcgacgctgggcccaaaggaaactattcccggtttatg
aaccacagctgccagcccaactgtgagaccctcaagtggacagtgaatggggacacccgc
gtaggcctgtttgctgtgtgtgacattcctgcagggacagagctgacttttaattataac
ctcgactgtttgggcaatgagaaaacagtctgtcggtgcggagcctccaactgcagtgga
tttcttggggacagaccaaagacctcagcatccctttcttcagaggaaaagggtaaaaag
accaagaagaaaaccaggaggcgcagagccaagggggagtggaagaggcagtcggaggat
gagtgtttccgctgtggtgacggtgggcagctggtgctgtgcgaccgcaagctctgcacc
aaggcttaccacctgtcctgcctgggcctgggcaagcggcccttcgggaagtgggagtgt
ccgtggcatcactgcgatgtgtgtggcaaaccttccatgtcgttctgccacctctgccca
aattcgctgtgtaaggagcaccaggacggggcatcattccgcactgcgcaggacgggcag
acctactgctgcgagcatgacttgggggcacaggcagggctgcgcagtggcaaggccgag
aagccccttccagagccggtgaagtccaaggggaagaggaggaaaaggcggtgctggcgg
cgggtcacggaggggaaatag

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