Heterocephalus glaber (naked mole rat): 101710283
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Entry
101710283 CDS
T02812
Gene name
Jak1
Definition
(RefSeq) Janus kinase 1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
hgl
Heterocephalus glaber (naked mole rat)
Pathway
hgl01521
EGFR tyrosine kinase inhibitor resistance
hgl04151
PI3K-Akt signaling pathway
hgl04217
Necroptosis
hgl04380
Osteoclast differentiation
hgl04550
Signaling pathways regulating pluripotency of stem cells
hgl04621
NOD-like receptor signaling pathway
hgl04630
JAK-STAT signaling pathway
hgl04658
Th1 and Th2 cell differentiation
hgl04659
Th17 cell differentiation
hgl05140
Leishmaniasis
hgl05145
Toxoplasmosis
hgl05152
Tuberculosis
hgl05160
Hepatitis C
hgl05161
Hepatitis B
hgl05162
Measles
hgl05163
Human cytomegalovirus infection
hgl05164
Influenza A
hgl05165
Human papillomavirus infection
hgl05166
Human T-cell leukemia virus 1 infection
hgl05167
Kaposi sarcoma-associated herpesvirus infection
hgl05168
Herpes simplex virus 1 infection
hgl05169
Epstein-Barr virus infection
hgl05171
Coronavirus disease - COVID-19
hgl05200
Pathways in cancer
hgl05203
Viral carcinogenesis
hgl05212
Pancreatic cancer
hgl05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101710283 (Jak1)
04151 PI3K-Akt signaling pathway
101710283 (Jak1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101710283 (Jak1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
101710283 (Jak1)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
101710283 (Jak1)
04658 Th1 and Th2 cell differentiation
101710283 (Jak1)
04659 Th17 cell differentiation
101710283 (Jak1)
09158 Development and regeneration
04380 Osteoclast differentiation
101710283 (Jak1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101710283 (Jak1)
05203 Viral carcinogenesis
101710283 (Jak1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101710283 (Jak1)
09162 Cancer: specific types
05212 Pancreatic cancer
101710283 (Jak1)
09171 Infectious disease: bacterial
05152 Tuberculosis
101710283 (Jak1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101710283 (Jak1)
05161 Hepatitis B
101710283 (Jak1)
05160 Hepatitis C
101710283 (Jak1)
05171 Coronavirus disease - COVID-19
101710283 (Jak1)
05164 Influenza A
101710283 (Jak1)
05162 Measles
101710283 (Jak1)
05168 Herpes simplex virus 1 infection
101710283 (Jak1)
05163 Human cytomegalovirus infection
101710283 (Jak1)
05167 Kaposi sarcoma-associated herpesvirus infection
101710283 (Jak1)
05169 Epstein-Barr virus infection
101710283 (Jak1)
05165 Human papillomavirus infection
101710283 (Jak1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101710283 (Jak1)
05140 Leishmaniasis
101710283 (Jak1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101710283 (Jak1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101710283 (Jak1)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101710283 (Jak1)
Protein kinases [BR:
hgl01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101710283 (Jak1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
Kinase-like
RIO1
SH2
Motif
Other DBs
NCBI-GeneID:
101710283
NCBI-ProteinID:
XP_004841577
LinkDB
All DBs
Position
Un
AA seq
1154 aa
AA seq
DB search
MQYLNIKEDCSAMAFCAKMRSSKKAEVNQVAPKPGVEVTFYLPDRGPLRLGTGEYTAEEL
CIQAAQECCISPLCHNLFALYDENTKLWYAPNRVITVDDKMSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKSSYEKRKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKVQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNTTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLRISSENEMN
WFHSSEGASTLCYEVMVTGNLGIQWRQKPNAVPAEKEKNKLKRKKLENKHKKDEEKNKVR
EEWSNFSYFPEITHIVIKESLVSINKQDNKNMELQLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSEQVLGGQKQFKNFQIEVQKGRYSLHGSDRGFPSLEELMSHLKKQILRTDNISFVL
KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSG
TLVDYRDDEGTAEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
LLAREGVDSEIGPFIKLSDPGIPVTVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCLNYDPNQRPFFRA
IMRDINKLEEQNPDIVSEKTPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
SGSLKEYLPKNKNKINLKQQLKYAVQICKGMEYLGSRQYVHRDLAARNVLVESEHQVKIG
DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDS
DSSPMALFLKMIGPTHGQMTVTRLVNALKEGKRLPCPPNCPDEVYQLMRKCWEFQPSSRT
TFQSLIEGFEALLK
NT seq
3465 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcagtgccatggcgttctgtgctaaaatgagg
agctccaagaaggccgaggtgaaccaggtggcgcccaagccaggggtggaggtgaccttc
tacctgccggaccggggccccctccggctgggcacaggagagtacacagcggaggagctg
tgcatccaggcggcgcaggagtgctgtatctctcctctgtgtcacaacctcttcgccctg
tacgatgagaacaccaagctctggtacgcacccaaccgtgtcatcaccgtcgacgacaag
atgtctctccggctccactaccgcatgaggttctacttcaccaactggcatgggaccaac
gacaacgagcagtcagtgtggcgacactcgccaaagaagcagaagagcagctatgagaag
aggaaggttcccgacgcaaccccgctcctggacgccagctccctggagtacctgttcgcg
cagggacagtacgatctggtcaagtgcctggcgcccatccgggaccccaagacggagcag
gacggacatgacattgagaacgagtgcctgggcatggccgtgctggccatctcgcactac
gccatgatgaagaaggtgcagctgccagagctgcccaaggacatcagctacaagcggtat
attccagaaacgttgaataagtccatcagacagaggaacctcctcacccggatgcggata
aataatgttttcaaggatttcctaaaggagtttaacaacacgaccatctgcgacagcagc
gtgtccacacacgatctcaaggtgaagtacctggccaccttggaaaccttgaccaaacat
tacggggctgaaatattcgagacttccatgttgcggatttcatcagaaaatgagatgaat
tggtttcactcgtctgagggtgcaagcacgctctgctacgaagtgatggtgaccggaaat
ctcgggatccagtggcggcagaaaccaaacgctgttcctgctgaaaaggagaaaaacaaa
ctgaagcggaaaaaactggaaaacaaacacaagaaggatgaggagaaaaacaaagtccgc
gaagagtggagcaacttctcgtacttccccgagatcactcacatcgtcataaaggagtcc
ttggtcagcattaacaagcaggacaacaagaacatggaactgcagctctcttcgcacgaa
gaggccttgtccttcgtgtccctggtggacgggtacttccggctcacggcagacgcccac
cactacctctgcactgatgtggctcctccgctgatcgtccacaacatacagaacggctgc
cacggcccaatctgcacggagtacgccatcaacaagctgcgccaggagggcagcgaggag
ggcatgtatgtgctgaggtggagctgcacggactttgacaacatcctcatgacggtcacc
tgcttcgagaagtccgagcaggtgctgggtggccagaagcagttcaagaacttccagatc
gaggtgcagaagggccgctacagcttgcatggctcggaccgtggcttccccagcctggag
gagctcatgagccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtgctg
aagcgctgctgccagcccaagccccgggaaatctccaacctgctggtggccaccaagaaa
gcccaggagtggcagcccgtctaccccatgagccagctgagcttcgatcggatcctcaag
aaagatatcatgcaaggcgagcacctcggcaggggcacaaggacgcacatctactctggg
acgctggtggactacagggacgacgaggggactgcggaggagaagaggataaaagtgatc
ctgaaagtgctggaccccagccacagggacatctctctggccttcttcgaagcagccagc
atgatgaggcaggtgtcgcacaagcacatcgtgtacctgtacggcgtgtgcgtgcgggat
gtggagaacatcatggtggaggagtttgtcgagggcggccccctggacctcttcatgcac
cgcaagagcgacgtcctcaccacaccctggaagttcaaggttgccaagcagctggccagc
gccctgagttacttggaggacaaagacctggtccatggaaacgtgtgcaccaagaacctc
ctgctggcccgagaaggcgtagacagtgagatcggcccgttcatcaagctcagcgaccca
ggcatccctgtcaccgtgctgtccaggcaagagtgcatcgagcggatcccctggatcgcc
cccgagtgcgtggaggactccaagaacctgagcgtggccgctgacaagtggagctttggc
accaccctctgggagatctgctacaatggcgagatcccgctgaaggacaagacactgatc
gagaaggagaggttctacgagagccgctgccggccggtgacgccatcctgcaaggagctg
gccgacctgatgacccgctgcctgaactatgaccccaaccagaggcccttcttccgtgcc
atcatgagggacatcaacaagctggaggagcagaatccagacatcgtttcagaaaaaaca
ccagccaccgaggtggatcccacgcattttgagaagcgcttcctgaagaggatccgtgac
ctgggagagggccactttggcaaggtggagctctgcaggtacgaccccgagggggacaac
accggggagcaggtggccgtcaagtccctcaagcccgagagcggaggcaatcacatagcc
gacctgaagaaggagatcgagatcctgaggaacctctaccacgagaacattgtcaagtac
aagggcatctgcacggaggatggaggaaacggcatcaagctcatcatggagttcctgccc
tcgggaagcctgaaggagtaccttcctaagaacaagaacaaaattaacctcaagcagcag
ctcaagtacgccgtgcagatctgtaagggcatggagtacctgggctcccggcagtacgtt
caccgcgacctggcagccagaaacgtcctggttgaaagtgagcaccaggtgaagatcggg
gactttgggctcaccaaggccatcgagaccgacaaggagtactacacggtcaaggacgac
cgcgacagccccgtattctggtacgcgccggagtgcctcatccagtgtaagttttacatt
gcctcagacgtctggtctttcggagtgaccctgcacgagctgctcacgtactgcgactcg
gactccagccccatggccttgttcctgaaaatgataggcccgacccatggccagatgaca
gtaaccagacttgtgaacgccctgaaggaaggaaaacgcttgccttgtccgcctaactgc
ccagatgaggtttatcagcttatgagaaaatgctgggaattccagccatccagccggaca
accttccagagccttattgaaggatttgaagcacttttaaaataa
DBGET
integrated database retrieval system
