Heterocephalus glaber (naked mole rat): 101718090
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Entry
101718090 CDS
T02812
Gene name
Tgfbr1
Definition
(RefSeq) transforming growth factor beta receptor 1
KO
K04674
TGF-beta receptor type-1 [EC:
2.7.11.30
]
Organism
hgl
Heterocephalus glaber (naked mole rat)
Pathway
hgl04010
MAPK signaling pathway
hgl04060
Cytokine-cytokine receptor interaction
hgl04068
FoxO signaling pathway
hgl04144
Endocytosis
hgl04218
Cellular senescence
hgl04350
TGF-beta signaling pathway
hgl04371
Apelin signaling pathway
hgl04380
Osteoclast differentiation
hgl04390
Hippo signaling pathway
hgl04520
Adherens junction
hgl04659
Th17 cell differentiation
hgl04926
Relaxin signaling pathway
hgl04933
AGE-RAGE signaling pathway in diabetic complications
hgl05142
Chagas disease
hgl05161
Hepatitis B
hgl05166
Human T-cell leukemia virus 1 infection
hgl05200
Pathways in cancer
hgl05210
Colorectal cancer
hgl05212
Pancreatic cancer
hgl05220
Chronic myeloid leukemia
hgl05225
Hepatocellular carcinoma
hgl05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101718090 (Tgfbr1)
04350 TGF-beta signaling pathway
101718090 (Tgfbr1)
04390 Hippo signaling pathway
101718090 (Tgfbr1)
04371 Apelin signaling pathway
101718090 (Tgfbr1)
04068 FoxO signaling pathway
101718090 (Tgfbr1)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
101718090 (Tgfbr1)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101718090 (Tgfbr1)
09143 Cell growth and death
04218 Cellular senescence
101718090 (Tgfbr1)
09144 Cellular community - eukaryotes
04520 Adherens junction
101718090 (Tgfbr1)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
101718090 (Tgfbr1)
09152 Endocrine system
04926 Relaxin signaling pathway
101718090 (Tgfbr1)
09158 Development and regeneration
04380 Osteoclast differentiation
101718090 (Tgfbr1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101718090 (Tgfbr1)
09162 Cancer: specific types
05210 Colorectal cancer
101718090 (Tgfbr1)
05212 Pancreatic cancer
101718090 (Tgfbr1)
05225 Hepatocellular carcinoma
101718090 (Tgfbr1)
05226 Gastric cancer
101718090 (Tgfbr1)
05220 Chronic myeloid leukemia
101718090 (Tgfbr1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101718090 (Tgfbr1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101718090 (Tgfbr1)
05161 Hepatitis B
101718090 (Tgfbr1)
09174 Infectious disease: parasitic
05142 Chagas disease
101718090 (Tgfbr1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101718090 (Tgfbr1)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
101718090 (Tgfbr1)
Protein kinases [BR:
hgl01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR1 family [OT]
101718090 (Tgfbr1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
TGF_beta_GS
Activin_recp
Pkinase_fungal
APH
FTA2
Motif
Other DBs
NCBI-GeneID:
101718090
NCBI-ProteinID:
XP_004864998
LinkDB
All DBs
Position
Un
AA seq
500 aa
AA seq
DB search
MESAAAAPRHQLLLLMLVAAATTLLPGAKTLQCFCQLCTKDNYTCVTDGLCFVSVTETTD
RVIHNTMCIAEIDLIPRDRPFVCAPSSKTGAVTTTYCCNQDHCNKIELPTTEKQSPGLGP
VELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYD
MTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWF
REAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMI
KLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATD
TIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHED
YQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARL
TALRIKKTLSQLSQQEGIKM
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
atggagtcggcggccgctgctccgcgtcaccagctgcttctcctcatgctggtggcggcg
gcgacgacgctgctcccgggggcgaagacattacagtgtttctgccagctctgtacaaaa
gacaattatacctgtgtgacagatgggctctgctttgtctctgtcacagagaccacagac
agagttatacacaataccatgtgtatagctgaaatcgatctaattcctcgagatagacca
tttgtatgtgcaccctcttcaaaaactggggctgtgactacaacatattgttgcaatcag
gatcattgcaataaaatagaactcccaactactgaaaagcagtcacctggccttggtccc
gtggagctggcagccgtcattgctggaccagtctgctttgtttgcatctcactcatgttg
atggtctatatctgccataaccgaactgttattcaccatcgagtgccaaatgaagaagat
ccttcattagatcgcccttttatttcagagggtactaccttaaaagatttaatttatgat
atgacaacgtcagggtctggatcaggtttaccattgcttgttcagagaacaattgcaaga
acaattgtgttacaagaaagcattggcaaaggtcgatttggagaagtttggcgaggaaag
tggcgaggagaagaagttgctgttaagatattctcctccagagaagaacgttcatggttc
cgtgaggcagagatttatcagactgtaatgttacgccatgaaaacatcctgggatttata
gcagcagacaataaggacaacggtacatggactcagctctggttggtgtcagattatcat
gagcatgggtccctttttgattacttgaatagatacacagttactgtggaaggaatgatc
aagcttgctctgtccacagcaagtggtcttgcccacctacacatggagatagttggtacc
caaggaaagccagccattgctcatagagatttgaaatcaaagaatatcttggtaaagaag
aatggaacctgctgtattgcagacttaggactggcagtaagacatgattcagctacggat
acaattgatattgctccaaaccacagagtgggaacaaaaaggtacatggcccctgaagtt
ctagatgattccataaatatgaaacattttgaatcctttaaacgtgctgacatctatgca
atgggcttagtattctgggaaatagctcggcgctgctccattggtggaattcatgaagat
taccagctgccttactatgatcttgtaccttctgatccatcagttgaagaaatgagaaaa
gtagtttgtgaacagaagctgaggccaaatattccaaacagatggcagagctgtgaagcc
ctgagagtgatggctaaaattatgagagaatgttggtatgctaatggagcagctaggctg
acagctttgaggattaagaaaacattgtcacaactcagtcaacaggaaggcatcaaaatg
taa
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