Heterocephalus glaber (naked mole rat): 101725029
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Entry
101725029 CDS
T02812
Gene name
Ptpn6
Definition
(RefSeq) protein tyrosine phosphatase, non-receptor type 6
KO
K05697
tyrosine-protein phosphatase non-receptor type 6 [EC:
3.1.3.48
]
Organism
hgl
Heterocephalus glaber (naked mole rat)
Pathway
hgl04520
Adherens junction
hgl04630
JAK-STAT signaling pathway
hgl04650
Natural killer cell mediated cytotoxicity
hgl04660
T cell receptor signaling pathway
hgl04662
B cell receptor signaling pathway
hgl05140
Leishmaniasis
hgl05205
Proteoglycans in cancer
hgl05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101725029 (Ptpn6)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
101725029 (Ptpn6)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
101725029 (Ptpn6)
04660 T cell receptor signaling pathway
101725029 (Ptpn6)
04662 B cell receptor signaling pathway
101725029 (Ptpn6)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
101725029 (Ptpn6)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101725029 (Ptpn6)
09174 Infectious disease: parasitic
05140 Leishmaniasis
101725029 (Ptpn6)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hgl01009
]
101725029 (Ptpn6)
Enzymes [BR:
hgl01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
101725029 (Ptpn6)
Protein phosphatases and associated proteins [BR:
hgl01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
101725029 (Ptpn6)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
DSPc
Y_phosphatase3
PTPlike_phytase
Motif
Other DBs
NCBI-GeneID:
101725029
NCBI-ProteinID:
XP_004869529
UniProt:
A0A0P6J0L6
LinkDB
All DBs
Position
Un
AA seq
596 aa
AA seq
DB search
MLSSGWFHRDLSGLDAETLLKGRGVDGSFLARPSSKNQGDFSLSVRVGDQVTHIRIQNSG
DFYDLYGGEKFATLTELVEFYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGM
QAEALLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKASMGSALKVTHIKVMCEGGRYTV
GGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKKEWED
TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHTRVILQRRDSSIPG
SDYINANYVKNQLLGLDESSKTYIASQGCLETTVNDFWQMVWQENTRVIVMTTREVEKGR
NKCVPYWPEVGTQHAYGHYSVTNCGEHDAAEYKLRTLQVSPLDNGDLIREIWHYQYLSWP
DHGVPSEPGGVLSFLDQINQRQEKLPHAGPIIVHCSAGIGRTGTIIVIDMLMESIATKGL
DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAMAQFIETTKKKLEVMQSQKGQESEYGN
ITYPPALKSAHAKAARTSSKHKEDVYENLHGKKKEEKVKKQRSSDKEKGKGSLRRK
NT seq
1791 nt
NT seq
+upstream
nt +downstream
nt
atgctgtccagcgggtggttccaccgggacctcagcgggctggacgcagagaccctgctc
aagggtcgcggtgtggatgggagcttcctggctcggcccagcagcaagaaccagggcgac
ttctcgctgtctgtcagggtaggggatcaggtgacccacattcggatccagaactcgggg
gacttctacgacctgtatggaggggagaagttcgccacgctgaccgagctggtggagttc
tacacgcagcagcagggtgtgctgcaggaccgggatggcaccatcatccacctcaagtac
ccactcaactgctccgaccccaccagcgagaggtggtaccatgggcacatgtcggggatg
caggcggaggcgctgctgcaggccaagggtgagccctggaccttcctggttcgcgagagc
ctcagccagcccggggacttcgtgctgtcagtgctcagtgaccagcccaaggccagcatg
ggctccgcactcaaggtcacccacatcaaggtcatgtgtgagggtggacgctacacggtg
ggcggctcggagacctttgacagcctcacagacctggtggagcatttcaagaagacgggg
attgaggaggcctcaggtgcctttgtctacctgcggcagccttactatgccactcgggtg
aatgcagccgacattgagaaccgggtcttggagctgaacaagaagaaggagtgggaggac
acggccaaggctggcttctgggaggagtttgagagtctgcagaagcaggaggtgaagaac
ttgcaccagcggctggaagggcagcggccggagaacaagagcaaaaaccgttacaagaac
attctcccctttgaccacacccgcgtgatcctgcagcgacgagacagtagcatccccggg
tccgactacataaatgccaactacgtcaagaaccagctgctaggcttggacgagagctct
aagacctacatcgccagccagggctgcctagagaccacggtcaacgacttctggcagatg
gtgtggcaggagaacacacgcgtcattgtcatgaccacccgggaggtggagaaaggccgg
aacaaatgtgtcccctactggccggaggtgggcactcagcacgcctatggacactactct
gtgaccaactgtggagagcacgacgcagccgagtacaaactccgcaccctgcaggtgtcc
ccgctggacaatggggacctgattcgggagatctggcactaccagtacctgagctggcct
gaccatggagtgcccagtgagcctgggggtgtcctcagcttcctggaccagatcaaccag
cggcaggagaagctgccccatgctgggcccatcattgtgcattgcagcgcgggcatcggc
cgcacgggcaccatcatcgtcatcgacatgctcatggagagcatcgccaccaaggggctg
gactgcgacatcgacatccagaagacgatccagatggtgcgggcacagcgctcgggcatg
gtgcagacagaggcgcagtacaagttcatctacgtggccatggcccagttcatcgagacc
acgaagaagaagctggaggtgatgcagtcccagaagggccaggagtcggagtacgggaac
atcacctacccgcccgccctgaagagcgcccacgccaaggccgcccggacctcctccaaa
cacaaggaggacgtctacgagaacctgcatggcaagaagaaggaggagaaggtgaagaag
cagcgatcctcggacaaggagaagggcaaaggttccctcaggaggaagtga
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