KEGG   Heterocephalus glaber (naked mole rat): 101725029
Entry
101725029         CDS       T02812                                 

Gene name
Ptpn6
Definition
(RefSeq) protein tyrosine phosphatase, non-receptor type 6
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
hgl04520  Adherens junction
hgl04630  JAK-STAT signaling pathway
hgl04650  Natural killer cell mediated cytotoxicity
hgl04660  T cell receptor signaling pathway
hgl04662  B cell receptor signaling pathway
hgl05140  Leishmaniasis
hgl05205  Proteoglycans in cancer
hgl05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    101725029 (Ptpn6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    101725029 (Ptpn6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    101725029 (Ptpn6)
   04660 T cell receptor signaling pathway
    101725029 (Ptpn6)
   04662 B cell receptor signaling pathway
    101725029 (Ptpn6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101725029 (Ptpn6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101725029 (Ptpn6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    101725029 (Ptpn6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hgl01009]
    101725029 (Ptpn6)
Enzymes [BR:hgl01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     101725029 (Ptpn6)
Protein phosphatases and associated proteins [BR:hgl01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    101725029 (Ptpn6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc Y_phosphatase3 PTPlike_phytase
Other DBs
NCBI-GeneID: 101725029
NCBI-ProteinID: XP_004869529
UniProt: A0A0P6J0L6
LinkDB
Position
Un
AA seq 596 aa
MLSSGWFHRDLSGLDAETLLKGRGVDGSFLARPSSKNQGDFSLSVRVGDQVTHIRIQNSG
DFYDLYGGEKFATLTELVEFYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGM
QAEALLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKASMGSALKVTHIKVMCEGGRYTV
GGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKKEWED
TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHTRVILQRRDSSIPG
SDYINANYVKNQLLGLDESSKTYIASQGCLETTVNDFWQMVWQENTRVIVMTTREVEKGR
NKCVPYWPEVGTQHAYGHYSVTNCGEHDAAEYKLRTLQVSPLDNGDLIREIWHYQYLSWP
DHGVPSEPGGVLSFLDQINQRQEKLPHAGPIIVHCSAGIGRTGTIIVIDMLMESIATKGL
DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAMAQFIETTKKKLEVMQSQKGQESEYGN
ITYPPALKSAHAKAARTSSKHKEDVYENLHGKKKEEKVKKQRSSDKEKGKGSLRRK
NT seq 1791 nt   +upstreamnt  +downstreamnt
atgctgtccagcgggtggttccaccgggacctcagcgggctggacgcagagaccctgctc
aagggtcgcggtgtggatgggagcttcctggctcggcccagcagcaagaaccagggcgac
ttctcgctgtctgtcagggtaggggatcaggtgacccacattcggatccagaactcgggg
gacttctacgacctgtatggaggggagaagttcgccacgctgaccgagctggtggagttc
tacacgcagcagcagggtgtgctgcaggaccgggatggcaccatcatccacctcaagtac
ccactcaactgctccgaccccaccagcgagaggtggtaccatgggcacatgtcggggatg
caggcggaggcgctgctgcaggccaagggtgagccctggaccttcctggttcgcgagagc
ctcagccagcccggggacttcgtgctgtcagtgctcagtgaccagcccaaggccagcatg
ggctccgcactcaaggtcacccacatcaaggtcatgtgtgagggtggacgctacacggtg
ggcggctcggagacctttgacagcctcacagacctggtggagcatttcaagaagacgggg
attgaggaggcctcaggtgcctttgtctacctgcggcagccttactatgccactcgggtg
aatgcagccgacattgagaaccgggtcttggagctgaacaagaagaaggagtgggaggac
acggccaaggctggcttctgggaggagtttgagagtctgcagaagcaggaggtgaagaac
ttgcaccagcggctggaagggcagcggccggagaacaagagcaaaaaccgttacaagaac
attctcccctttgaccacacccgcgtgatcctgcagcgacgagacagtagcatccccggg
tccgactacataaatgccaactacgtcaagaaccagctgctaggcttggacgagagctct
aagacctacatcgccagccagggctgcctagagaccacggtcaacgacttctggcagatg
gtgtggcaggagaacacacgcgtcattgtcatgaccacccgggaggtggagaaaggccgg
aacaaatgtgtcccctactggccggaggtgggcactcagcacgcctatggacactactct
gtgaccaactgtggagagcacgacgcagccgagtacaaactccgcaccctgcaggtgtcc
ccgctggacaatggggacctgattcgggagatctggcactaccagtacctgagctggcct
gaccatggagtgcccagtgagcctgggggtgtcctcagcttcctggaccagatcaaccag
cggcaggagaagctgccccatgctgggcccatcattgtgcattgcagcgcgggcatcggc
cgcacgggcaccatcatcgtcatcgacatgctcatggagagcatcgccaccaaggggctg
gactgcgacatcgacatccagaagacgatccagatggtgcgggcacagcgctcgggcatg
gtgcagacagaggcgcagtacaagttcatctacgtggccatggcccagttcatcgagacc
acgaagaagaagctggaggtgatgcagtcccagaagggccaggagtcggagtacgggaac
atcacctacccgcccgccctgaagagcgcccacgccaaggccgcccggacctcctccaaa
cacaaggaggacgtctacgagaacctgcatggcaagaagaaggaggagaaggtgaagaag
cagcgatcctcggacaaggagaagggcaaaggttccctcaggaggaagtga

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