Heterocephalus glaber (naked mole-rat): 101726020
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Entry
101726020 CDS
T02812
Symbol
Shmt1
Name
(RefSeq) serine hydroxymethyltransferase 1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl00260
Glycine, serine and threonine metabolism
hgl00630
Glyoxylate and dicarboxylate metabolism
hgl00670
One carbon pool by folate
hgl01100
Metabolic pathways
hgl01200
Carbon metabolism
hgl01230
Biosynthesis of amino acids
hgl01240
Biosynthesis of cofactors
hgl01523
Antifolate resistance
Module
hgl_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
101726020 (Shmt1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
101726020 (Shmt1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101726020 (Shmt1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101726020 (Shmt1)
Enzymes [BR:
hgl01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
101726020 (Shmt1)
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Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
101726020
NCBI-ProteinID:
XP_004868733
UniProt:
G5BMY1
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All DBs
Position
Un
AA seq
483 aa
AA seq
DB search
MMTSVNGAHKNAALWSSHETMLAQPLKDSDIEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEILCQKRALQAYHLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADENGAYLMADMAHISGLVAAGV
VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVCSMDPKTGKETLYNLESIINSAVFPGL
QGGPHNHAIAGVAVALKQAMTTEFKIYQLQVVANSRALSEALTELGYKIVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTTRGLLEKDFQK
VAYFIHKGIELTLQIQNDMGSRATLKEFKEKLADEKHQRAVQALRDEVESFASLFPLPGL
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NT seq
1452 nt
NT seq
+upstream
nt +downstream
nt
atgatgacttcagtcaatggagcccataagaatgctgccctgtggtcctcccatgaaact
atgctagcacagcctctcaaggacagtgacattgaggtgtacaacatcattaagaaggag
agtaaccggcagcgagtgggattggagctgattgcctcagagaatttcgccagccgggca
gttctggaggcccttggctcctgtttaaataacaaatactctgaggggtacccaggccag
agatattatggcgggactgaatttattgatgaactggagatactgtgtcagaagcgagca
ctgcaagcctatcatctggacccacaatgctggggggtcaacgtccagccctactcaggc
tcccctgcaaactttgcagtgtatactgccctggtggagccccatgggcgcatcatgggc
ctggacctccctgatgggggccacctgacccatgggttcatgacagacaagaagaaaatc
tctgctacatccatcttctttgaatctatgccctataaggtgtatccagacactggctac
atcaactacgaccagctggaggaaaatgctcgcctcttccacccaaagctgatcatcgct
ggaaccagctgctattctcgaaacctggactatgcacgtttgcggaagattgcagatgag
aatggagcatatcttatggcagacatggcacacatcagtgggctggtggcagctggcgtg
gtcccctccccttttgagcactgccatgtggtgaccaccacaacccacaagaccctgaga
ggctgccgtgctggcatgatcttctacaggaaaggagtgtgcagcatggatcccaagact
ggcaaagagaccctatataatctggagtcgatcatcaattccgctgtgttcccaggcctg
cagggaggcccccacaaccacgccattgctggtgttgctgtggccctgaagcaagccatg
actacagaattcaaaatctatcagcttcaggtggtggccaactccagagctctgtctgag
gcccttacggagctgggttacaaaattgtcacaggtggctctgacaaccatttgatcctt
gtggatctacgttccaagggcacagatggtggaagggctgagaaggtgctagaagcctgt
tctattgcctgcaacaagaatacttgcccaggtgacagaagcgcactgaggcccagtgga
ctgcgactggggactccagcactgacaacccgaggacttttggaaaaagacttccaaaaa
gttgcatactttatccataagggtatagagctgactctacagattcagaacgacatgggc
tcaagggccacgctgaaggagttcaaggaaaagctggcagatgagaagcaccagagggct
gtacaggctctccgggatgaagtagagagctttgcttcgctcttcccactgcctggccta
cctgacttctga
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