Heterocephalus glaber (naked mole rat): 106007527 Help Entry 106007527         CDS       T02812                                  Gene name Egf Definition (RefSeq) epidermal growth factor   KO K04357   epidermal growth factor Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl01521   EGFR tyrosine kinase inhibitor resistance hgl04010   MAPK signaling pathway hgl04012   ErbB signaling pathway hgl04014   Ras signaling pathway hgl04015   Rap1 signaling pathway hgl04020   Calcium signaling pathway hgl04066   HIF-1 signaling pathway hgl04068   FoxO signaling pathway hgl04072   Phospholipase D signaling pathway hgl04151   PI3K-Akt signaling pathway hgl04510   Focal adhesion hgl04540   Gap junction hgl04630   JAK-STAT signaling pathway hgl04810   Regulation of actin cytoskeleton hgl05160   Hepatitis C hgl05165   Human papillomavirus infection hgl05200   Pathways in cancer hgl05210   Colorectal cancer hgl05212   Pancreatic cancer hgl05213   Endometrial cancer hgl05214   Glioma hgl05215   Prostate cancer hgl05218   Melanoma hgl05219   Bladder cancer hgl05223   Non-small cell lung cancer hgl05224   Breast cancer hgl05226   Gastric cancer hgl05231   Choline metabolism in cancer hgl05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     106007527 (Egf)    04012 ErbB signaling pathway     106007527 (Egf)    04014 Ras signaling pathway     106007527 (Egf)    04015 Rap1 signaling pathway     106007527 (Egf)    04630 JAK-STAT signaling pathway     106007527 (Egf)    04066 HIF-1 signaling pathway     106007527 (Egf)    04068 FoxO signaling pathway     106007527 (Egf)    04020 Calcium signaling pathway     106007527 (Egf)    04072 Phospholipase D signaling pathway     106007527 (Egf)    04151 PI3K-Akt signaling pathway     106007527 (Egf)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     106007527 (Egf)    04540 Gap junction     106007527 (Egf)   09142 Cell motility    04810 Regulation of actin cytoskeleton     106007527 (Egf)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     106007527 (Egf)    05231 Choline metabolism in cancer     106007527 (Egf)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     106007527 (Egf)   09162 Cancer: specific types    05210 Colorectal cancer     106007527 (Egf)    05212 Pancreatic cancer     106007527 (Egf)    05226 Gastric cancer     106007527 (Egf)    05214 Glioma     106007527 (Egf)    05218 Melanoma     106007527 (Egf)    05219 Bladder cancer     106007527 (Egf)    05215 Prostate cancer     106007527 (Egf)    05213 Endometrial cancer     106007527 (Egf)    05224 Breast cancer     106007527 (Egf)    05223 Non-small cell lung cancer     106007527 (Egf)   09172 Infectious disease: viral    05160 Hepatitis C     106007527 (Egf)    05165 Human papillomavirus infection     106007527 (Egf)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     106007527 (Egf)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     106007527 (Egf) Cytokines and growth factors [BR:hgl04052]  Growth factors   Growth factors (RTK binding)    106007527 (Egf) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ldl_recept_b FXa_inhibition EGF_CA cEGF EGF EGF_3 DUF5050 EGF_MSP1_1 hEGF Tr-sialidase_C Plasmod_Pvs28 Motif Other DBs NCBI-GeneID:  106007527 NCBI-ProteinID:  XP_004867639 LinkDB All DBs Position Un AA seq 853 aa AA seqDB search MKEAGPAQESRYSELASCPGSASECSHDCVLTLEGPHCFCPEGSVLEADGKTCSGCSSPG NGGCSQLCIPLGPVSWECGCFPGYDLQLDQKSCVASGPQPLLLFANSRDIRRMHFDGTDY EILLSQQMGTVLALDHDPVENKIYFAHTALKWIERANMDGSQRERLIEEAVDAPEGLAVD WIGRRLYWTDRGKSVIEGSDVNGKHREIIIKENISQPRGIAVHPMAKRLFWTDVGTNPRV ESASLQGADRRVIASSELAEPSGLTIDLLTDTLYWCDAQLSVVEMANLDGSRRQRLAQDD VGHPFAVAVFEDHLWLSDWAAPSVTRVHKRTGQNRVRLRGSVLKPSSLVVVHPLAKPGAD PCSHLGGACEQICQERFGTAQCSCLRGFRSALDGRTCLALRSLPPSAGGDADHSRQGTAP DHFSGTKASEDNTTGAQRLLVAEIMVSDEDDCSPVACAVHAQCTPEGDGATCRCSEGFAG DGELCSDVDECAADSTACPSPSSECINTEGGYVCRCSAGYRGDGLRCLDIDECQLQVHSC GPGANCTNTEGGYTCWCAGGPSAPGLPCPESTSTPPLGEDGGGLVRNGYPGCPPSHSGFC LHGGVCMYIEAVDTYACNCVIGYVGERCQHRDLRWWELRHAGHGQHRDVTVAAICVVALV LLLLLGLWGARCYRCRSLGLYSEPTAACRANSAAFTHSHSRASSLVFWKIPHVRMKKLAL KTPKNPYEESCRDVSSRRPADGEAGVSACPQPWFVVLKEDQNFRTVSHPTSGKNGQMADV GQLPSLEPDQLPLWRQEPHICGVGTEQGRWAPLSSDKEPGPQVMERSFHLPSYVAKPLAV GVQKPHPLQSADP NT seq 2562 nt NT seq  +upstreamnt  +downstreamnt atgaaagaagctgggccagcccaggaatcccgctactcagaattagcttcctgtccgggc agtgcatccgaatgcagccacgactgtgtcctaacattggagggcccccattgtttctgt cctgaaggttccgtgctggaggcagacggaaagacgtgtagcggctgctcgtcacctggt aacggtggctgtagccagctctgcattcccctcggcccggtgtcctgggagtgtggttgc tttcctgggtacgacctgcaactggaccagaagagttgtgtggcttcaggaccacagcca cttttgctctttgccaactctcgagacatccgacgcatgcactttgacgggacagactat gaaatcctgctcagccagcagatgggaacggttcttgcactggatcacgacccggtggag aataagatatattttgcccacacagccctgaagtggatagagagggctaacatggacggg tcccagagagaaaggctcattgaggaagcagtggatgcaccagaaggtcttgctgtggac tggattggccgtagactctactggacagacagagggaaatctgtcattgaagggagtgat gtaaatggaaaacatcgagaaataatcattaaggaaaatatctctcagccacgaggaatt gctgttcatcccatggccaagcgattgttctggaccgacgtggggacgaatccacgagtg gaaagcgcttccctgcagggcgctgaccggcgggttatcgccagctcagagctggcggag cctagcggactcactatcgacctcctgaccgacaccctgtactggtgcgatgcccagctg tctgtggtcgagatggccaatctggatggctccaggcgccagaggctggcccaggacgat gtaggccacccgtttgccgtggctgtgttcgaggaccacctgtggctgtcggactgggcc gcgccgtcggtaacgagggtgcacaagaggactggccaaaacagggtacgtctgcgaggc agcgtgctgaagccctcctcgctggttgtggttcacccactggcaaaaccaggcgcggac ccctgctctcacctgggtggcgcctgcgagcagatctgccaggagaggttcgggaccgct cagtgttcctgtctcagaggtttccggagcgccctggacgggaggacgtgcctggctctg aggagtctcccgccttcggccggtggtgacgctgatcacagtcggcaggggacagcacca gaccacttttctgggactaaggcatcagaagacaacaccacaggagctcagcgcctgcta gtggccgaaatcatggtgtcagatgaggatgactgttcccctgtggcgtgtgccgtgcac gctcagtgcactccggagggcgacggcgccacctgccggtgttcggaggggttcgctggg gatggagaactatgctcggatgtagacgaatgtgcggcggacagcaccgcctgcccttcc ccctcctccgagtgcatcaacacggaaggcggctacgtgtgcaggtgctcggccgggtac cgcggagacgggctacgctgtctggacatcgatgagtgccagctgcaggtgcacagctgc gggccaggagccaactgcacaaacacggagggtggctacacctgctggtgcgccggcggc ccttctgcgcccgggctgccctgtcctgagtcgacctcaacccctccccttggggaagat ggcggcggtctggtcagaaatggttacccgggatgtcccccctcacacagcgggttctgc ctccacggcggagtgtgcatgtacatcgaagcagtagacacctacgcctgcaactgtgtc atcggctacgtcggggagcgctgccagcaccgagacctcagatggtgggagctgcgccac gccggccacgggcagcatcgggacgtcacggtggcagccatctgtgtggtggcgctggtc ctgctgctcctcctggggctgtggggggcacgctgctacaggtgcaggtctctgggatta tacagtgaacccactgccgcctgcagagccaactcagccgcatttacccacagccactcc agggccagcagcctcgtgttctggaagattccacacgtcaggatgaagaagctggcgctg aaaaccccgaagaatccttatgaggagtcgtgcagagacgtgagcagtcggaggccggcc gacggcgaggctggggtgtctgcctgcccccaaccttggttcgtggtcttaaaggaagat cagaacttcaggactgtgagtcatcctacgtctggcaagaatggccagatggcagatgtt ggccagcttccctccctggagcctgatcaactgcctttgtggagacaggagccccacata tgtggagtgggcacagagcaaggccgctgggccccactgtccagcgataaggaacctggt ccccaggtcatggagcgaagctttcatctcccctcctatgtggcaaagcccctcgctgtg ggggttcagaagccccatcctctccagtcagctgacccatga

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