Haemophilus influenzae KR494 (serotype f): HifGL_000853
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Entry
HifGL_000853 CDS
T02839
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
hik
Haemophilus influenzae KR494 (serotype f)
Pathway
hik00260
Glycine, serine and threonine metabolism
hik00261
Monobactam biosynthesis
hik00270
Cysteine and methionine metabolism
hik00300
Lysine biosynthesis
hik01100
Metabolic pathways
hik01110
Biosynthesis of secondary metabolites
hik01120
Microbial metabolism in diverse environments
hik01230
Biosynthesis of amino acids
Module
hik_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
hik_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
hik00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
HifGL_000853 (thrA)
00270 Cysteine and methionine metabolism
HifGL_000853 (thrA)
00300 Lysine biosynthesis
HifGL_000853 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
HifGL_000853 (thrA)
Enzymes [BR:
hik01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
HifGL_000853 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
HifGL_000853 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AGV11674
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All DBs
Position
851927..854374
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AA seq
815 aa
AA seq
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MRVLKFGGTSLANPERFSQAAKLIEQAHLEEQAAGVLSAPAKITNHLVALSEKAALNQPT
DTHFNEAIEIFYNIINGLHTENNQFDLNGIKALIDAEFAQIKELLEEIRQAGKVEDAVKA
TIDCRGEKLSIAMMKAWFEARGYSVHIVDPVKQLLAKGGYLESSVEIEESTKRVDAASIE
KDKVVLMAGFTAGNEKGELVLLGRNGSDYSAACLAACLGASVCEIWTDVDGVYTCDPRLV
PDARLLPTLSYREAMELSYFGAKVIHPRTIGPLLPQNIPCVIKNTGNPSAPGSIIDGNVK
SEGLQVKGITNLDNLAMFNVSGPGMQGMVGMASRVFSAMSGAGISVILITQSSSEYSISF
CVPVKSAEVAKTVLETEFANELNEHQLEAIEVIKDLSIISVVGDGMKQAKGIAARFFSAL
AQANISIVAIAQGSSERSISAVVPQNKAIEAVKATHQALFNNKKVVDMFLVGVGGVGGEL
IEQVKSQKEYLAKKNVEIRVCAIANSNRMLLDENGLNLEDWKTDLENATQPSDFDVLLSF
IKLHHVVNPVFVDCTSAESVAGLYARALKEGFHVVTPNKKANTRELAYYNELRQNAQASH
HKFLYETNVGAGLPVIENLQNLLAAGDELEYFEGILSGSLSFIFGKLEEGLSLSEVTALA
REKGFTEPDPRDDLSGQDVARKLLILAREAGIELELSDVEVEGVLPKGFSEGKSADEFMA
MLPQLDEEFKARVSTAKAEGKVLRYVGKIREGKCKVSIVAVDQNNPLYKVKDGENALAFY
TRYYQPIPLLLRGYGAGNAVTAAGIFADILRTLQH
NT seq
2448 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgtacttaaatttggcggcacttcgcttgcaaatccagaacgtttttcccaagcg
gcgaaattgatcgagcaagctcatttagaagagcaggctgctggtgttttatcagcacca
gccaaaataactaatcatctcgtcgccctttctgaaaaagctgcattaaatcaaccaacc
gatacacatttcaacgaagcaatcgaaattttctataatatcatcaatggcttgcatacc
gaaaataatcaattcgacttaaatggcatcaaggcgcttattgatgctgaatttgctcaa
atcaaagaattattagaagaaattcgtcaggcaggaaaagtagaagatgcagttaaagcg
acgattgattgccgtggtgaaaaactttctatcgcaatgatgaaagcttggtttgaagcg
cgtggctatagtgtacatattgtggatcctgtcaaacaattattggcaaaaggcggttat
cttgagtcttctgttgaaattgaagaatcaacaaaacgtgttgatgcagcaagtatcgaa
aaagataaagtggtgttgatggcaggttttactgcgggtaatgaaaaaggtgagttggtg
ctgctcggtcgtaatggctcagactattctgcagcctgtttagccgcttgtttaggtgca
agcgtatgcgaaatttggaccgatgtggatggcgtttatacttgcgatccgcgtttagtg
cctgatgcccgtttattaccaaccctttcttatcgtgaagcaatggaactttcttatttc
ggcgcgaaagtcattcatcctcgtacgattggcccattgttgccacaaaatattccttgt
gtcattaaaaatacaggaaatccttctgcaccaggttctattattgatggcaatgtgaaa
tcagaaggtttacaagtcaaaggtatcactaacttagacaatttggcgatgtttaatgta
tcaggccctggtatgcaaggcatggtaggtatggcatctcgtgtattttcagctatgtca
ggcgcaggcatttcagttattttaattactcagtcttcatctgaatatagtattagtttc
tgcgtgccagtgaaatctgcagaagtagcgaaaactgtgttagaaactgagtttgctaat
gaattaaatgagcatcaattagaagcaattgaagtgattaaagatttatccattatttct
gttgtgggcgatggaatgaaacaagcgaagggcattgctgctcgtttcttctctgcgtta
gcacaggcaaatattagcattgtagcgattgcacagggttctagtgaacgttcaatttct
gcagttgtgccacaaaataaagcgatcgaagccgtaaaagctacccatcaggcacttttc
aataataaaaaagtcgtggatatgtttttagtgggcgttggtggagtaggcggagaatta
atagagcaggtaaagagccaaaaggagtatttagcaaagaagaatgttgaaattcgtgtc
tgcgctatagcaaattctaatcgtatgttgcttgatgaaaatggattaaatttagaggat
tggaaaaccgatttagaaaatgcgactcagccatcagattttgatgtattgctttctttc
attaaattacatcatgtggtaaaccctgtatttgtagattgtacttcggcggagtctgtt
gcagggctttatgctcgtgcgttaaaagaaggtttccatgtggttacaccaaataaaaaa
gcgaatacacgagaattagcatattacaatgaattacgtcaaaatgctcaagcaagccac
cataagtttttgtatgaaaccaatgtgggcgcaggtttaccagttattgaaaatcttcaa
aacttacttgccgcaggcgatgaacttgaatattttgaaggtattttatctggctcgctt
tcctttatttttggtaaattagaagagggactttctctttcagaagtcaccgcacttgcg
cgagaaaaaggctttactgagccagatccccgtgatgacctttcaggacaagatgtagcg
cgtaaattattaattctggctcgtgaagcaggaattgaacttgaactttccgatgttgaa
gttgaaggtgtattgccgaaaggcttttctgaaggaaaatctgcagatgaatttatggca
atgttgccgcagcttgatgaagagtttaaagctcgtgtttccaccgctaaagctgaaggc
aaagtattgcgttatgttggaaaaattcgtgaaggtaaatgtaaagtatctattgttgca
gtggatcagaataacccactttacaaagtaaaagatggcgaaaatgctttggcattttat
actcgttattaccaacctatcccacttttattacgtggttatggcgcaggcaatgcagtt
actgcggcaggtatctttgcagatattttaagaacattacaacattaa
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