Haemophilus influenzae 10810 (serotype b): HIB_11260
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Entry
HIB_11260 CDS
T01720
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
hiu
Haemophilus influenzae 10810 (serotype b)
Pathway
hiu00290
Valine, leucine and isoleucine biosynthesis
hiu00620
Pyruvate metabolism
hiu01100
Metabolic pathways
hiu01110
Biosynthesis of secondary metabolites
hiu01210
2-Oxocarboxylic acid metabolism
hiu01230
Biosynthesis of amino acids
Module
hiu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hiu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
HIB_11260
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HIB_11260
Enzymes [BR:
hiu01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
HIB_11260
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
NAD_binding_10
RdfA
Motif
Other DBs
NCBI-ProteinID:
CBW29313
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All DBs
Position
1150413..1151960
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AA seq
515 aa
AA seq
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MTDRVIIFDTTLRDGEQALKASLTVKEKLQIALALERLGVDVMEVGFPVSSQGDFESVQT
IARHIKNARVAALSRAVDKDIDAAYEALKVAEAFRIHTFIASSALHVEAKLKRSFDDVVG
MAVAAVKRARNYTDDVEFSCEDAGRTGIDNICRIVEAAINAGATTVNIPDTVGFCLPNEY
GNIIAQVRNCVPNIDKAVISVHCHNDLGMATANSLTAVQNGARQIECTINGIGERAGNTS
LEEVVMAMKVRQDFMGVDTRINTQEIHRISQMVSQLCNMPIQPNKAIVGSNAFAHSSGIH
QDGMLKNKNTYEIMSPETIGLKKEKLNLTARSGRAAVKGHMADMGYTEQDYDLDKLYDSF
LKLADKKGQVFDYDLEALAFIDMQQGDEDRLVLDKLSAHSTKEYPATAFVQLKLDGEKLS
TSSIGGNGPVDAVYNAILNLTGLEIKMSHYNLTAKGEGAEALGQVDIVVEHKGRKFHGVG
LATDIVESSALALVHAINAIYRAHKVADIKNHKHH
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgacagatcgcgttattatttttgataccaccttgcgtgatggggaacaggcattaaaa
gcaagtttgacggtaaaagaaaaattacagatcgctttagcacttgaacgcttaggtgtg
gatgtaatggaagtagggtttcctgtttcttctcaaggggattttgaatctgttcaaacc
attgctcgccatattaaaaacgctcgtgttgccgcgttatctcgagcggtagataaagac
attgatgccgcatacgaggcattgaaagttgctgaagcattccgtattcatacgtttatt
gcaagttccgcattgcacgttgaagcgaaattaaaacgttcttttgatgatgtggtagga
atggcagttgcagcagtgaaacgcgcacgtaattatacggatgatgttgagttttcttgc
gaagatgcggggcgtacaggcattgataatatctgtcgtattgtagaggcggcaattaat
gcgggtgcaactacggtaaatattcccgatacagtcggtttttgcttaccaaatgaatac
ggcaatatcattgctcaagtgcgtaattgcgtgccgaatattgataaagcagtgatttcc
gtgcattgccacaatgacttaggtatggcaaccgctaattctttaacggcagtacaaaat
ggtgcgcgccaaattgaatgtaccattaatggaattggtgaacgtgcaggcaatacttcc
cttgaagaagtggttatggcaatgaaagtgcgtcaggattttatgggtgtggatacccgt
attaatacccaagaaattcaccgtatcagccaaatggttagccaactttgtaatatgccg
attcagccgaataaagccattgtgggttcgaatgcttttgcccattcttctggtatccat
caagatggtatgttgaaaaacaaaaatacctacgaaattatgtctccagaaaccattgga
ttgaaaaaagaaaaattaaatttaaccgcacgttctggtcgtgcagctgtgaaaggtcat
atggcagatatgggttacaccgaacaagattatgatttggataaattgtatgactctttc
ttaaaattggcggataaaaaaggtcaagtgtttgattatgatttggaagcattggcgttt
atcgatatgcaacaaggggatgaggatcgtttggtattagataaactttcggcacactcc
accaaagaatatccagcaactgcgtttgttcaattgaagttggatggcgaaaaattaagt
acgtcttcaattggcggtaatggcccagtggatgcggtttataacgccatcttaaattta
acgggtttagaaatcaaaatgtctcactataacttaactgctaaaggcgagggcgcagaa
gcattagggcaagtggatattgtggtggaacacaaagggcgtaaattccacggcgtcggt
ttagcaacagacattgttgaatcttccgcacttgctttagtccacgccatcaatgccatt
tatcgagcgcataaagtggcagatattaagaatcataaacatcattaa
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