Haemophilus influenzae 477: NTHI477_00956
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Entry
NTHI477_00956 CDS
T03720
Symbol
purL
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
hiw
Haemophilus influenzae 477
Pathway
hiw00230
Purine metabolism
hiw01100
Metabolic pathways
hiw01110
Biosynthesis of secondary metabolites
Module
hiw_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
hiw00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NTHI477_00956 (purL)
Enzymes [BR:
hiw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NTHI477_00956 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AJO87979
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All DBs
Position
complement(973948..977841)
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AA seq
1297 aa
AA seq
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MTVKTFRGSPALSEFRLTQLQQKCQQYQLPITSVYAEYLHFVEQKTSLVEDEIVKLQALL
HYGSMFSELKPAGYCLIVTPRVGTISSWSSKATDIAHNCGLSKVNRIERGIAYYFNIERD
LTEAELATLKDLLHDRMLETVLNHETEAALLFTQQEPKALTTIDILNGGRQALEQANIAL
GLALADDEMDYLVESFTALKRNPQDVELYMFAQANSEHCRHKIFNADWIIDGKKQDKSLF
KMIKNTFEQTPDFVLSAYKDNAAVMEGSKVGRWFPDPDGQYRVHQEDAHILMKVETHNHP
TAISPFPGAATGSGGEIRDEGATGRGAKPKAGLTGFSVSNLVIPNFEQPWENPLSKPNRI
ASALDIMIDAPLGSAAFNNEFGRPALLGYFRTYEEKVNSFAGKEVRGYHKPIMLAGGIGN
IRGEQVQKGEIPIGAKLIVLGGAAMNIGLGGGAASSMDSGKSKEDLDFASVQRENPEMER
RCQEVIDRCWQLGEENPILFIHDVGAGGLSNAMPELVHDGKRGGKFDLRSILCDEKGMSP
LEIWCNESQERYVLAVAPENLELFTALCERERAPFAVIGEATQAEHLILHDSHFDNNPID
LPMNVLLGKTPKMTREVLSKTVENQPLKTECIQLKEAFHRVLRLPVVAEKTFLITIGDRS
VTGMVARDQMVGPWQIPVSDVAVTTASLDSYHGEAMAMGERSPVALLNFSASARLAVAEA
ITNIAGTHIGEMKRIKLSANWMSAAGHTGEDAGLYEAVKAVGEELCPALGLTIPVGKDSM
SMKTTWIDNGEKKSVTAPLSLVISAFARVEDVRKTLTPQLRTDKGFSSLLLIDLGEGHNR
LGATALAQVYKQLGDKPADVVKVQRLKDFYNAMQILVAEDKLLAYHDRSDGGLITTLAEM
AFAGHCGVEVDISALGDNDLAVLFNEELGAVIQVADSQLESVREVLKAHNLLGITHQLGT
VTVDDRFEISRSSHKLFSEKRSELRSIWAELTYQMQRLRDNPECAEQEFEAKKNPDDKGL
SAFLTYDVNEDITAPFINKGVKPTIAILREQGVNSHYEMAAAFDRAGFNAIDVHMSDLMI
GRRNLAEFNAMVACGGFSYGDVLGAGGGWAKSILFNPKLHEQFSQFFINPNTLILGVCNG
CQMISNLAEIIPGTENWPHFVRNKSERFEARVSLVKINEVDSVWFAGMAGSHMPIAVSHG
EGQVKFKSVEQFAGLKAQGIIAAQYIDNNGSPTELYPANPNGSAEGITAITNLDGRVAIM
MPHPERVFRAVSNSWHPENWTEDGAWMRLFRNARMVF
NT seq
3894 nt
NT seq
+upstream
nt +downstream
nt
atgactgtcaaaacctttcgtggctcgcctgctctttctgaatttcgtttaactcaactt
caacaaaaatgccagcaatatcaattgcctattacgtcagtttatgcagagtatttgcat
tttgttgaacaaaaaacatcgcttgtagaagatgaaatcgttaaattacaagcattattg
cattatggatcaatgttttctgaactcaagcctgcaggatattgtttaattgtgactcca
cgagtggggacaatttcctcttggtcttcaaaagcgacagacatcgctcacaattgtggt
ttgtcgaaggtaaatcgtattgaacgtggtatagcctattacttcaatattgagcgtgat
ttaaccgaagcagaattggctacgctgaaagatttattacacgaccgtatgttagaaacc
gtgttaaatcacgaaacagaagcagccttgctttttactcaacaagaacccaaagcatta
actaccattgatattttaaatggtggccgtcaagcattagaacaggcgaatattgccttg
ggtttagcgttggcagatgatgagatggattatttagtggaaagttttactgccttaaag
cgtaatccacaggatgtggagctttatatgtttgcacaagcgaattcagagcattgtcgc
cataaaatttttaatgccgattggattattgatggcaaaaaacaggataaatcgctgttt
aaaatgatcaaaaatacctttgagcaaacgcctgattttgtgctttctgcttataaagat
aatgctgcagtaatggaaggttcgaaagtcgggcgttggtttcctgatcctgatggacaa
tatcgtgttcatcaagaagatgcgcacattttaatgaaagtggaaacacataaccatccc
acagcaatttcgccatttcctggtgccgcaacaggctctggcggggagattcgtgatgaa
ggggcaacggggcgtggggcaaaacccaaagcaggtttaacaggtttctcggtgtctaac
ctcgttattccaaactttgaacaaccttgggaaaatccattgtctaaaccaaatcgcatt
gcttctgccttagatattatgatagatgcgcctttaggtagtgcggcatttaataatgaa
tttggtcgcccagcattattaggttatttccgtacttatgaagaaaaagtaaatagtttt
gcaggaaaagaagtacgcggttatcacaagccgattatgttagcgggaggaatcggtaat
attcgtggcgaacaggttcaaaaaggcgaaattccaatcggtgctaaattgatcgtgttg
ggtggggcagcaatgaacatcggtttaggtggtggtgctgcttcttcgatggacagtggt
aaatcaaaagaagatttagattttgcttctgttcaacgtgaaaatccggaaatggaacgc
cgctgccaagaagttattgaccgctgttggcaattaggcgaagaaaatccaatcctgttt
attcacgatgtgggtgcgggtggtttatctaatgcaatgcctgaattggtacacgatggc
aagcgtggaggaaaattcgatctgcgttctattctttgtgatgaaaaaggtatgtcgcca
ttggaaatttggtgtaatgaatcgcaagaacgttatgtattagccgttgcgccagaaaac
ctcgaattatttaccgcactttgtgagcgtgaacgtgccccttttgcagtgattggcgaa
gcaacacaagcagaacatttaatcttgcacgatagtcatttcgataataatccaattgat
ttaccaatgaatgtgttattaggcaaaacgccgaaaatgacgcgtgaggttttgtcaaaa
acagtggaaaatcaaccacttaaaacagaatgtattcaattaaaagaagcattccaccgt
gtattacgtttacccgttgttgcagaaaaaactttcttaattactattggcgaccgttct
gtaacaggtatggtggcacgagatcaaatggtgggtccttggcaaatccccgtgtctgat
gtggctgttactactgcttcactggatagctaccacggcgaagcaatggcaatgggcgaa
cgttctccagttgccttgctaaatttctcggcttcggcacgtttagctgtggcggaggcc
attactaacattgctggcacccacattggcgagatgaaacgtattaaactttctgccaac
tggatgagtgcagcaggtcacacaggcgaagatgcgggactttatgaagcagtaaaagct
gtgggcgaagaactttgtcctgcgttaggcttaactattcctgtgggtaaagactcaatg
tcgatgaaaaccacttggatcgataatggcgagaaaaaatcagtgactgccccactttca
ttagtaatttccgcttttgctcgtgtagaagatgtacgtaaaacgcttacgccacaactt
cgtaccgacaaaggtttctcgagtttattgctaattgatttaggcgaagggcataatcga
ttaggtgcgaccgcacttgctcaagtgtacaaacagttaggagacaagcctgccgatgtg
gtaaaggttcaacgcttaaaagatttttacaatgcaatgcaaattttagtggcagaagat
aaattgttggcttatcacgaccgttcggacggcggtttaatcacaactcttgcggaaatg
gcgtttgcagggcattgtggggtagaagttgatatttcagctttaggcgacaacgattta
gcggtattatttaacgaagaattgggagcggttatccaagttgccgatagccaattagaa
agcgtacgtgaggtgttgaaagctcacaatttgcttggtattacccaccaacttggtacg
gtaactgttgatgatcgctttgaaatcagccgcagcagccataaattattcagcgaaaaa
cgctctgaattacgtagtatttgggcagaattaacttaccaaatgcaacgcttacgcgat
aatccagagtgtgctgagcaagagtttgaagctaagaaaaaccctgacgacaaaggctta
tccgcatttttgacttacgatgtgaatgaagatattactgcgccatttatcaataaaggt
gtaaaaccaaccattgcaattttacgtgaacaaggtgtaaatagccattatgaaatggca
gcagcgtttgatcgtgcaggctttaatgcaattgacgtgcatatgtctgatttaatgatt
ggtcgtcgtaatttagccgaattcaatgcaatggttgcttgtggcggtttctcttacggc
gatgtgcttggcgcagggggcggttgggcaaaatccatcttatttaacccgaaattacac
gagcaattcagccagttttttatcaatccaaacacactgatcttaggcgtatgtaacggt
tgtcaaatgatctctaacttggcggaaattatcccaggtacagaaaactggccgcatttt
gtacgcaacaaatctgaacgctttgaagcgcgtgtgagtttagtgaaaattaatgaagtg
gattcagtttggtttgcaggaatggcaggctcacatatgcccattgcggtttctcacggg
gaagggcaagttaagtttaaatcagttgaacagtttgcaggcttaaaagcacaaggcatc
attgccgcacaatatattgacaacaacggtagccccactgaactatatcctgctaatccg
aatggttctgcggagggcattactgcaattacaaatcttgatgggcgagttgctattatg
atgccacaccctgaacgtgtgttccgtgctgtgagtaactcttggcacccagaaaactgg
acagaagacggtgcgtggatgagattattcagaaatgcaagaatggtattttag
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