Halobacillus litoralis: HLI_18375
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Entry
HLI_18375 CDS
T05828
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
hli
Halobacillus litoralis
Pathway
hli00790
Folate biosynthesis
hli01100
Metabolic pathways
hli01240
Biosynthesis of cofactors
Module
hli_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
hli00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HLI_18375
Enzymes [BR:
hli01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HLI_18375
6.3.2.17 tetrahydrofolate synthase
HLI_18375
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QAS54706
UniProt:
A0A410MJ52
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Position
3670346..3671641
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AA seq
431 aa
AA seq
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MNYQDAIDWIHSREKFKVKPGLKRMSWMMEKLGHPEAKLRVIHIAGTNGKGSTVSFLRHL
LQAQGYSVGTFTSPYIEKFNERISMNGLAISDESLALLVERMKPLAEELQRTPLGEPTEF
EIITAMAMVYFSHQHLNYVLIETGLGGRYDSTNIVTPILSAITNIGLDHMNILGSTIEQI
AEEKAGIIKKGVPVVTGVKQAEAWKVIHQQAEKCDADLYTLGKEFYVEHSGSIPDGEVFS
FKNKEYTTDELLSSMKGPHQVENAALALQTMEIMKSQGVLIDRSLYGIGVKQTTWPARFE
KVMNTPLTIIDGAHNEEGTRALVETVKSHYDGKKIALVYAALEDKPVKKMLKQLSDIADV
VYATTFDFPRSLSAPDLAELSPIKETFAVSQYSEAIELAAEEVGQNGVLLITGSLYFISN
VRKYFESRAAL
NT seq
1296 nt
NT seq
+upstream
nt +downstream
nt
atgaactaccaagatgcaattgactggatccactcaagagagaaattcaaagtaaaacct
gggttaaagcgaatgtcgtggatgatggaaaaactgggtcatccagaagcaaaactccgt
gtcatccatatcgctggtacaaacggtaaaggatcaacggtttcttttttgcgccacttg
ctccaagcacaaggctattcagttggcacgtttacgtcgccctatatagaaaaattcaat
gaaagaatcagtatgaacgggctggcgatttccgatgaatcccttgctctccttgtagaa
agaatgaagcctttagctgaagaactgcagcgtacaccacttggcgaaccaacagagttt
gaaatcatcacagctatggcgatggtttatttctcacaccagcatttaaattatgttctg
attgaaacgggcttaggaggaaggtatgattcgaccaatattgtaacgcctatcctttca
gctattacgaatatcggtcttgatcatatgaacatcctcgggtccacgatagaacagatt
gcagaagaaaaagctggcatcattaaaaaaggggtccctgttgtgacaggagtcaagcaa
gcggaggcttggaaagtcattcaccagcaagctgaaaaatgtgatgcagatttgtacacc
ttaggaaaagagttctatgttgaacatagcggaagcattcctgatggagaagtattctct
ttcaagaataaagaatatactacagacgaattgttaagttcaatgaaaggcccacatcaa
gtagagaatgctgcattagcactccagacaatggaaattatgaaatctcaaggtgtgctc
atagatcgtagcctgtatggaattggagtcaaacagacaacttggccggcacgatttgaa
aaagtgatgaacacgcctttgactatcatcgacggcgctcataatgaagaagggacccga
gcccttgttgagacagtgaaaagccactacgacggcaaaaaaatcgctttagtatatgcc
gctttagaggataaacccgtcaaaaaaatgttgaaacaactgagtgatatagcagatgtg
gtttatgctacgacctttgattttccgaggtctttatctgcccccgacttagctgaactt
tcccccattaaagagacttttgcagtatcgcaatattctgaggcgattgaactagctgca
gaagaggtgggacaaaatggtgtattattgattacaggctccttatatttcatctcaaat
gtaaggaaatattttgaatcaagagcagctctatga
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